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5H-PYRROLO[3,2-d]PYRIMIDINE-2,4-DIAMINO COMPOUNDS AND ANTIBODY CONJUGATES THEREOF App 20220242871 - MADERNA; Andreas ;   et al. | 2022-08-04 |
Bifunctional cytotoxic agents containing the CTI pharmacophore Grant 11,365,263 - Maderna , et al. June 21, 2 | 2022-06-21 |
Cyclopentane-Based Modulators of STING (Stimulator of Interferon Genes) App 20210230196 - Wythes; Martin James ;   et al. | 2021-07-29 |
Cyclopentane-based modulators of STING (stimulator of interferon genes) Grant 10,968,242 - Wythes , et al. April 6, 2 | 2021-04-06 |
Bifunctional Cytotoxic Agents Containing The Cti Pharmacophore App 20210061923 - MADERNA; Andreas ;   et al. | 2021-03-04 |
Immunomodulator Antibody Drug Conjugates And Uses Thereof App 20200405813 - YAM; Alice ;   et al. | 2020-12-31 |
Bifunctional cytotoxic agents containing the CTI pharmacophore Grant 10,870,706 - Maderna , et al. December 22, 2 | 2020-12-22 |
Substituted quinazoline and pyridopyrimidine derivatives useful as anticancer agents Grant 10,662,204 - Planken , et al. | 2020-05-26 |
Cyclopentane-Based Modulators of STING (Stimulator of Interferon Genes) App 20200102334 - Wythes; Martin James ;   et al. | 2020-04-02 |
Tetrahydroquinazoline derivatives useful as anticancer agents Grant 10,590,115 - Planken , et al. | 2020-03-17 |
3-indol substituted derivatives, pharmaceutical compositions and methods for use Grant 10,544,095 - Ninkovic , et al. Ja | 2020-01-28 |
Cyclopentane-based modulators of STING (stimulator of interferon genes) Grant 10,538,542 - Wythes , et al. Ja | 2020-01-21 |
Cyclopentane-Based Modulators of STING (Stimulator of Interferon Genes) App 20190284216 - Wythes; Martin James ;   et al. | 2019-09-19 |
Bifunctional cytotoxic agents Grant 10,391,182 - Maderna , et al. A | 2019-08-27 |
Tetrahydroquinazoline Derivatives Useful as Anticancer Agents App 20190248767 - PLANKEN; Simon ;   et al. | 2019-08-15 |
Substituted Quinazoline and Pyridopyrimidine Derivatives Useful as Anticancer Agents App 20190233440 - PLANKEN; Simon ;   et al. | 2019-08-01 |
Bifunctional Cytotoxic Agents App 20180339060 - MADERNA; Andreas ;   et al. | 2018-11-29 |
Bifunctional cytotoxic agents Grant 10,086,085 - Maderna , et al. October 2, 2 | 2018-10-02 |
Novel 3-indol Substituted Derivatives, Pharmaceutical Compositions And Methods For Use App 20180222862 - Ninkovic; Sacha ;   et al. | 2018-08-09 |
3-indol substituted derivatives, pharmaceutical compositions and methods for use Grant 9,873,690 - Ninkovic , et al. January 23, 2 | 2018-01-23 |
Derivatives Of N-(arylamino) Sulfonamides As Inhibitors Of Mek App 20170183333 - Maderna; Andreas ;   et al. | 2017-06-29 |
Bifunctional Cytotoxic Agents Containing The Cti Pharmacophore App 20160271270 - MADERNA; Andreas ;   et al. | 2016-09-22 |
Novel 3-indol Substituted Derivatives, Pharmaceutical Compositions And Methods For Use App 20160272628 - Ninkovic; Sacha ;   et al. | 2016-09-22 |
Preparation of (R)-N-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxyphenyl)-1-(2,- 3-dihydroxypropyl)cyclopropane-1-sulfonamide and (S)-N-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxyphenyl)-1-(2,- 3-dihydroxypropyl)cyclopropane-1-sulfonamide Grant 9,296,686 - Maderna , et al. March 29, 2 | 2016-03-29 |
Cytotoxic peptides and antibody drug conjugates thereof Grant 9,249,186 - Doroski , et al. February 2, 2 | 2016-02-02 |
Cytotoxic Peptides And Antibody Drug Conjugates Thereof App 20150307551 - DOROSKI; Matthew David ;   et al. | 2015-10-29 |
Preparation Of (r)-n-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxyphenyl)-1-(2,- 3-dihydroxypropyl)cyclopropane-1-sulfonamide And (s)- N-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxyphenyl)-1-(2,3-di- Hydroxypropyl)cyclopropane-1-sulfonamide App 20150274651 - MADERNA; Andreas ;   et al. | 2015-10-01 |
Cytotoxic peptides and antibody drug conjugates thereof Grant 9,138,486 - Doroski , et al. September 22, 2 | 2015-09-22 |
Bifunctional Cytotoxic Agents App 20150209445 - MADERNA; Andreas ;   et al. | 2015-07-30 |
Derivatives Of N-(arylamino) Sulfonamides As Inhibitors Of Mek App 20140378466 - Maderna; Andreas ;   et al. | 2014-12-25 |
Cytotoxic Peptides And Antibody Drug Conjugates Thereof App 20140363452 - DOROSKI; Matthew David ;   et al. | 2014-12-11 |
Preparation of (R)-N-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxyphenyl)-1-(2,- 3-dihydroxypropyl)cyclopropane-1-sulfonamide and (S)-N-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxyphenyl)-1-(2,- 3-dihydroxypropyl)cyclopropane-1-sulfonamide Grant 8,884,058 - Maderna , et al. November 11, 2 | 2014-11-11 |
Derivatives of N-(arylamino)sulfonamides as inhibitors of MEK Grant 8,829,052 - Maderna , et al. September 9, 2 | 2014-09-09 |
Cytotoxic peptides and antibody drug conjugates thereof Grant 8,828,401 - Doroski , et al. September 9, 2 | 2014-09-09 |
Preparation Of (r)-n-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxyphenyl)-1-(2,- 3-dihydroxypropyl)cyclopropane-1-sulfonamide And (s)- N-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxyphenyl)-1-(2,3-di- Hydroxypropyl)cyclopropane-1-sulfonamide App 20130261320 - MADERNA; Andreas ;   et al. | 2013-10-03 |
Preparation of (R)-N-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxyphenyl)-1-(2,- 3-dihydroxypropyl)cyclopropane-1-sulfonamide and (S)-N-3,4-difluoro-2(2-fluoro-4-iodophenylamino)-6-methoxyphenyl)-1-(2,3-- dihydroxypropyl)cyclopropane-1-sulfonamide Grant 8,513,443 - Maderna , et al. August 20, 2 | 2013-08-20 |
Cytotoxic Peptides And Antibody Drug Conjugates Thereof App 20130129753 - DOROSKI; Matthew David ;   et al. | 2013-05-23 |
Preparation Of (r)-n-(3,4-difluoro-2-(2-fluoro-4-iodophenylamin0)-6-methoxyphenyl)-1-(2,- 3-dihydroxypropyl)cyclopropane-1-sulfonamide And (s)- N-(3,4-difluoro-2-(2-fluoro-4-iodophenylamin0)-6-methoxyphenyl)-1-(2,3-di- Hydroxypropyl)cyclopropane-1-sulfonamide App 20120178946 - Maderna; Andreas ;   et al. | 2012-07-12 |
Derivatives Of N-(arylamino)sulfonamides As Inhibitors Of Mek App 20120022076 - MADERNA; Andreas ;   et al. | 2012-01-26 |
Derivatives of N-(arylamino) sulfonamides as inhibitors of MEK Grant 8,101,799 - Maderna , et al. January 24, 2 | 2012-01-24 |
Inhibitors of MEK Grant 8,063,049 - Koh , et al. November 22, 2 | 2011-11-22 |
Inhibitors Of Mek App 20100331334 - Koh; Yung-hyo ;   et al. | 2010-12-30 |
Inhibitors of MEK Grant 7,820,664 - Vernier , et al. October 26, 2 | 2010-10-26 |
Derivatives of N-(arylamino) sulfonamides as inhibitors of MEK Grant 7,759,518 - Maderna , et al. July 20, 2 | 2010-07-20 |
Phenylamino isothiazole carboxamidines as MEK inhibitors Grant 7,652,047 - Abdellaoui , et al. January 26, 2 | 2010-01-26 |
Derivatives Of N-(arylamino) Sulfonamides As Inhibitors Of Mek App 20090082457 - MADERNA; Andreas ;   et al. | 2009-03-26 |
Phenylamino Isothiazole Carboxamidines As Mek Inhibitors App 20080306063 - Abdellaoui; Hassan ;   et al. | 2008-12-11 |
Benzo[C][2,7]Naphtyridine Derivatives, Methods of Making Thereof and Methods of Use Thereof App 20080293712 - WISSNER; Allan ;   et al. | 2008-11-27 |
Inhibitors of MEK App 20080255133 - Vernier; Jean-Michel ;   et al. | 2008-10-16 |
Phenylamino isothiazole carboxamidines as MEK inhibitors Grant 7,429,667 - Abdellaoui , et al. September 30, 2 | 2008-09-30 |
Derivatives Of N-(arylamino) Sulfonamides As Inhibitors Of Mek App 20080058340 - Maderna; Andreas ;   et al. | 2008-03-06 |
Phenylamino isothiazole carboxamidines as MEK inhibitors App 20060194802 - Abdellaoui; Hassan ;   et al. | 2006-08-31 |
Ether and ester derivatives of the perborate icosahedron Grant 6,664,426 - Hawthorne , et al. December 16, 2 | 2003-12-16 |