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Pharmaceutical composition comprising (1R,4R)-6'- fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro [cyclohexane-1,1'-pyrano- [3,4,b ]indol] -4-amine and paracetamol or propacetamol Grant 11,311,504 - Frosch , et al. April 26, 2 | 2022-04-26 |
3-((Hetero-)Aryl)-8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives App 20210214315 - Kuehnert; Sven ;   et al. | 2021-07-15 |
3-((Hetero-)Aryl)-8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives App 20210188860 - KUEHNERT; Sven ;   et al. | 2021-06-24 |
3-((hetero-)aryl)-alkyl-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane Derivatives App 20210179592 - Kuehnert; Sven ;   et al. | 2021-06-17 |
3-(Carboxymethyl)-8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives App 20210179627 - KUEHNERT; Sven ;   et al. | 2021-06-17 |
8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives App 20210179595 - KUEHNERT; Sven ;   et al. | 2021-06-17 |
3-((Hetero-)Aryl)-8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives App 20210032256 - KUEHNERT; Sven ;   et al. | 2021-02-04 |
3-(Carboxymethyl)-8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives App 20200399280 - KUEHNERT; Sven ;   et al. | 2020-12-24 |
8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives App 20200399255 - KUEHNERT; Sven ;   et al. | 2020-12-24 |
3-((Hetero-)Aryl)-8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives App 20200399226 - KUEHNERT; Sven ;   et al. | 2020-12-24 |
3-((hetero-)aryl)-alkyl-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane Derivatives App 20200399252 - KUEHNERT; Sven ;   et al. | 2020-12-24 |
3-((hetero-)aryl)-alkyl-8-amino-2-oxo-l,3-diaza-spiro-[4.5]-decane derivatives Grant 10,829,480 - Kuehnert , et al. November 10, 2 | 2020-11-10 |
3-(carboxymethyl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives Grant 10,807,989 - Kuehnert , et al. October 20, 2 | 2020-10-20 |
3-((hetero-)aryl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives Grant 10,807,988 - Kuehnert , et al. October 20, 2 | 2020-10-20 |
8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives Grant 10,793,556 - Kuehnert , et al. October 6, 2 | 2020-10-06 |
3-((hetero-)aryl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives Grant 10,793,528 - Kuehnert , et al. October 6, 2 | 2020-10-06 |
3-((hetero-)aryl)-alkyl-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane Derivatives App 20200002319 - KUEHNERT; Sven ;   et al. | 2020-01-02 |
3-(Carboxymethyl)-8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives App 20190382407 - KUEHNERT; Sven ;   et al. | 2019-12-19 |
3-((Hetero-)Aryl)-8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives App 20190375718 - KUEHNERT; Sven ;   et al. | 2019-12-12 |
3-((Hetero-)Aryl)-8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives App 20190375754 - KUEHNERT; Sven ;   et al. | 2019-12-12 |
8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives App 20190375738 - KUEHNERT; Sven ;   et al. | 2019-12-12 |
Pharmaceutical Composition Comprising (1r,4r)-6'-fluoro-n,n-dimethyl-4-phenyl-4',9'-dihydro-3'h-spiro [cyclohexane-1,1'-pyrano-[ App 20190350884 - FROSCH; Stefanie ;   et al. | 2019-11-21 |
Pharmaceutical composition comprising (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexa- ne-1,1'-pyrano[3,4,b]indo]-4-amine and antidepressants Grant 10,328,055 - Frosch , et al. | 2019-06-25 |
3-(carboxymethyl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane Derivatives App 20190106430 - KUEHNERT; Sven ;   et al. | 2019-04-11 |
3-((Hetero-)Aryl)-8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives App 20190106429 - Kuehnert; Sven ;   et al. | 2019-04-11 |
8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane Derivatives App 20190100515 - KUEHNERT; Sven ;   et al. | 2019-04-04 |
3-(carboxyethyl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane Derivatives App 20190100497 - KUEHNERT; Sven ;   et al. | 2019-04-04 |
Substituted azaspiro(4.5)decane derivatives Grant 10,214,520 - Wegert , et al. Feb | 2019-02-26 |
Substituted azaspiro(4.5)decane derivatives Grant 10,202,345 - Wegert , et al. Feb | 2019-02-12 |
3-((hetero-)aryl)-alkyl-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane Derivatives App 20180327392 - KUEHNERT; Sven ;   et al. | 2018-11-15 |
3-(carboxymethyl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane Derivatives App 20180282341 - KUEHNERT; Sven ;   et al. | 2018-10-04 |
8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane Derivatives App 20180273516 - KUEHNERT; Sven ;   et al. | 2018-09-27 |
3-(carboxyethyl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane Derivatives App 20180273491 - KUEHNERT; Sven ;   et al. | 2018-09-27 |
Pharmaceutical composition comprising (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexa- ne-1,1'-pyrano-[3,4,b]indol]-4-amine and a propionic acid derivative Grant 10,076,510 - Frosch , et al. September 18, 2 | 2018-09-18 |
3-((Hetero-)Aryl)-8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives App 20180201616 - Kuehnert; Sven ;   et al. | 2018-07-19 |
Pharmaceutical Composition Comprising (1r,4r)-6'-fluoro-N, N-dimethyl-4-phenyl-4',9' -dihydro-3'H-spiro[cyclohexane-1,1' -pyrano[3,4,b]indol]-4-amine and Paracetamol or Propacetamol App 20180092867 - FROSCH; Stefanie ;   et al. | 2018-04-05 |
Process or preparing spirocyclic cyclohexane compounds, compositions containing such compounds and method of using such compounds Grant 9,862,719 - Hinze , et al. January 9, 2 | 2018-01-09 |
Pharmaceutical composition comprising (1r,4r)-6'-fluoro-N,N-di methyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano-[3,4,b]in- dol]-4-amine and a salicylic acid component Grant 9,855,286 - Frosch , et al. January 2, 2 | 2018-01-02 |
Cis-tetrahydro-spiro(cyclohexane-1,1?-pyrido[3,4-b]indole)-4-amine Compounds App 20170313703 - LINZ; Klaus ;   et al. | 2017-11-02 |
Substituted Azaspiro(4.5)Decane Derivatives App 20170210734 - WEGERT; Anita ;   et al. | 2017-07-27 |
3-((Hetero-)Aryl)-8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives App 20170197970 - KUEHNERT; Sven ;   et al. | 2017-07-13 |
3-((Hetero-)Aryl)-Alkyl-8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives App 20170197947 - KUEHNERT; Sven ;   et al. | 2017-07-13 |
3-(Carboxymethyl)-8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives App 20170197971 - KUEHNERT; Sven ;   et al. | 2017-07-13 |
8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives App 20170197949 - KUEHNERT; Sven ;   et al. | 2017-07-13 |
3-(Carboxyethyl)-8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives App 20170197919 - KUEHNERT; Sven ;   et al. | 2017-07-13 |
Pharmaceutical composition comprising (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexa- ne-1,1'-pyrano[3,4,b]indol]-4-amine and a gabapentinoid Grant 9,629,825 - Frosch , et al. April 25, 2 | 2017-04-25 |
Pharmaceutical Composition Comprising (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexa- ne-1,1'-pyrano[3,4,b]indo]-4-amine and Antidepressants App 20170065560 - Frosch; Stefanie ;   et al. | 2017-03-09 |
Substituted 4-aminocyclohexane derivatives Grant 9,580,386 - Nolte , et al. February 28, 2 | 2017-02-28 |
Spirocyclic Cyclohexane Compounds Useful To Treat Substance Dependency App 20160271107 - FRIDERICHS; Elmar ;   et al. | 2016-09-22 |
Substituted 4-aminocyclohexane derivatives Grant 9,403,767 - Nolte , et al. August 2, 2 | 2016-08-02 |
Pharmaceutical Composition Comprising (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexa- ne-1,1'-pyrano-[3,4,b]indol]-4-amine and a Propionic Acid Derivative App 20160199349 - FROSCH; Stefanie ;   et al. | 2016-07-14 |
Pharmaceutical composition comprising (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexa- ne-1,1'-pyrano[3,4,b]indol]-4-amine and a gabapentinoid App 20160193183 - FROSCH; Stefanie ;   et al. | 2016-07-07 |
Cis-tetrahydro-spiro(cyclohexane-1, 1' -pyrido[3,4-b]indole)-4-amine Compounds App 20160159787 - LINZ; Klaus ;   et al. | 2016-06-09 |
Pharmaceutical composition comprising (1r,4r)-6'-fluoro-N, N-dimethyl-4-phenyl-4,9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano[3,4,b]- indol]-4-amine and an anticonvulsant Grant 9,345,689 - Frosch , et al. May 24, 2 | 2016-05-24 |
Pharmaceutical composition comprising (1r,4r)-6'-flouro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexa- ne-1,1'-pyrano-[3,4,b]indol]-4-amine and a propionic acid derivative Grant 9,320,729 - Frosch , et al. April 26, 2 | 2016-04-26 |
Pharmaceutical composition comprising (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4'9'-dihydro-3'H-spiro[cyclohexan- e-1,1'-pyrano[3,4,b]indol]-4-amine and a gabapentinoid Grant 9,320,725 - Frosch , et al. April 26, 2 | 2016-04-26 |
Pharmaceutical composition comprising (1 r,4r) -6'-fluoro-N ,N-dimethyl-4-phenyl-4',9'-d ihydro-3'H-spiro[cyclohexane-1,1'-pyrano-[3,4,b]indol]-4-amine and an oxicam Grant 9,308,196 - Frosch , et al. April 12, 2 | 2016-04-12 |
Substituted Azaspiro(4.5)Decane Derivatives App 20160016903 - WEGERT; Anita ;   et al. | 2016-01-21 |
Mixed ORL1/mu-agonists for the Treatment of Pain App 20150342929 - LINZ; Klaus ;   et al. | 2015-12-03 |
Process for Preparing Spirocyclic Cyclohexane Compounds, Compositions Containing Such Compounds and Method of Using Such Compounds App 20150322080 - HINZE; Claudia ;   et al. | 2015-11-12 |
Process for preparing spirocyclic cyclohexane compounds, compositions containing such compounds and method of using such compounds Grant 9,120,797 - Hinze , et al. September 1, 2 | 2015-09-01 |
Pharmaceutical composition comprising (1r,4r) -6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'- -pyrano[3,4,b]indol]-4-amine and a NSAR Grant 8,912,226 - Frosch , et al. December 16, 2 | 2014-12-16 |
Substituted 4-aminocyclohexane Derivatives App 20140357634 - NOLTE; BERT ;   et al. | 2014-12-04 |
Spirocyclic Cyclohexane Compounds Useful To Treat Substance Dependency App 20140303125 - FRIDERICHS; Elmar ;   et al. | 2014-10-09 |
Substituted 4-aminocyclohexane derivatives Grant 8,835,689 - Nolte , et al. September 16, 2 | 2014-09-16 |
Pharmaceutical Composition Comprising (1r,4r)-6'-flouro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexa- ne-1,1'-pyrano-[3,4,b]indol]-4-amine and a propionic acid derivative App 20130324581 - FROSCH; Stefanie ;   et al. | 2013-12-05 |
Pharmaceutical Composition Comprising (1r,4r)-6'-fluoro-N, N-dimethyl-4-phenyl-4,9' -dihydro-3'H-spiro[cyclohexane-1,1' -pyrano[3,4,b]indol]-4-amine and an Anticonvulsant App 20130317009 - FROSCH; Stefanie ;   et al. | 2013-11-28 |
Pharmaceutical Composition Comprising (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexa- ne-1,1'-pyrano-[3,4,b]indol]-4-amine and a Salicylic Acid Component App 20130317076 - FROSCH; Stefanie ;   et al. | 2013-11-28 |
Pharmaceutical Composition Comprising (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexa- ne-1,1'-pyrano[3,4,b]indol]-4-amine and a NSAR App 20130317075 - FROSCH; Stefanie ;   et al. | 2013-11-28 |
Pharmaceutical Composition Comprising (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexa- ne-1,1'-pyrano[3,4,b]indol]-4-amine and Antidepressants App 20130310385 - FROSCH; Stefanie ;   et al. | 2013-11-21 |
Pharmaceutical Composition Comprising (1r,4r)-6'-fluoro-N, N-dimethyl-4-phenyl-4,9' -dihydro-3'H-spiro[cyclohexane-1,1' -pyrano[3,4,b]indol]-4-amine and Paracetamol or Propacetamol App 20130310435 - FROSCH; Stefanie ;   et al. | 2013-11-21 |
Pharmaceutical composition comprising (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4'9'-dihydro-3'H-spiro[cyclohexan- e-1,1'-pyrano[3,4,b]indol]-4-amine and a gabapentinoid App 20130310434 - FROSCH; Stefanie ;   et al. | 2013-11-21 |
Pharmaceutical composition comprising (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexa- ne-1,1'-pyrano-[3,4,b]indol]-4-amine and an oxicam App 20130310371 - FROSCH; Stefanie ;   et al. | 2013-11-21 |
(1r,4r)-6'-Fluoro-(N-methyl- or N,N-dimethyl-)-4-phenyl-4',9'-dihydro-3'H-spiro-[cyclohexane-1,1'-pyrano[- 3,4,b]indol]-4-amine for Treating Fibromyalgia and Chronic Fatigue Syndrome App 20130202701 - FROSCH; Stefanie ;   et al. | 2013-08-08 |
Substituted 4-aminocyclohexane Derivatives App 20130197095 - NOLTE; Bert ;   et al. | 2013-08-01 |
Spirocyclic azaindole derivatives Grant 8,399,503 - Zemolka , et al. March 19, 2 | 2013-03-19 |
Substituted cyclohexyldiamines Grant 8,357,705 - Zemolka , et al. January 22, 2 | 2013-01-22 |
Substituted spirocyclic cyclohexane derivatives Grant 8,293,758 - Zemolka , et al. October 23, 2 | 2012-10-23 |
Hydroxymethylcyclohexylamines Grant 8,288,406 - Frormann , et al. October 16, 2 | 2012-10-16 |
Spiro(5.5)undecane derivatives Grant 8,288,430 - Zemolka , et al. October 16, 2 | 2012-10-16 |
Substituted 4-aminocyclohexane Derivatives App 20120202810 - NOLTE; Bert ;   et al. | 2012-08-09 |
Substituted heteroaryl derivatives Grant 8,138,187 - Zemolka , et al. March 20, 2 | 2012-03-20 |
Cis-tetrahydro-spiro(cyclohexane-1,1'-pyrido[3,4-b]indole)-4-amine Compounds App 20120029006 - Linz; Klaus ;   et al. | 2012-02-02 |
Process for Preparing Spirocyclic Cyclohexane Compounds, Compositions Containing Such Compounds and Method of Using Such Compounds App 20110319440 - HINZE; Claudia ;   et al. | 2011-12-29 |
Compositions containing spirocyclic cyclohexane compounds Grant 8,053,576 - Hinze , et al. November 8, 2 | 2011-11-08 |
Spirocyclic cyclohexane compounds useful to treat substance dependency Grant 8,034,936 - Friderichs , et al. October 11, 2 | 2011-10-11 |
(Hetero)aryl cyclohexane derivatives Grant 7,977,370 - Zemolka , et al. July 12, 2 | 2011-07-12 |
Spirocyclic cyclohexane compounds Grant 7,951,948 - Hinze , et al. May 31, 2 | 2011-05-31 |
Hydroxymethylcyclohexylamines App 20110059999 - Frormann; Sven ;   et al. | 2011-03-10 |
Spirocyclic Cyclohexane Compounds Useful To Treat Substance Dependency App 20110053970 - FRIDERICHS; Elmar ;   et al. | 2011-03-03 |
Mixed Orl1/mu-agonists For The Treatment Of Pain App 20110015220 - LINZ; KLAUS ;   et al. | 2011-01-20 |
Spirocyclic Cyclohexane Compounds App 20100240897 - Hinze; Claudia ;   et al. | 2010-09-23 |
Spirocyclic cyclohexane compounds Grant 7,799,931 - Hinze , et al. September 21, 2 | 2010-09-21 |
Spiro(5.5)undecane Derivatives App 20090247505 - ZEMOLKA; Saskia ;   et al. | 2009-10-01 |
Substituted 4-aminocyclohexane Derivatives App 20090247530 - NOLTE; Bert ;   et al. | 2009-10-01 |
(hetero)aryl Cyclohexane Derivatives App 20090247573 - Zemolka; Saskia ;   et al. | 2009-10-01 |
Substituted Spirocyclic Cyclohexane Derivatives App 20090247561 - Zemolka; Saskia ;   et al. | 2009-10-01 |
Substituted Cyclohexyldiamines App 20090247591 - Zemolka; Saskia ;   et al. | 2009-10-01 |
Substituted 4-aminocyclohexane derivatives App 20090215725 - SCHUNK; Stefan ;   et al. | 2009-08-27 |
Spirocyclic Cyclohexane Compounds App 20090163716 - HINZE; Claudia ;   et al. | 2009-06-25 |
Spirocyclic Azaindole Derivatives App 20090156593 - Zemolka; Saskia ;   et al. | 2009-06-18 |
Process for Preparing Spirocyclic Cyclohexane Compounds and Methods of Using Such Compounds App 20090156626 - Hinze; Claudia ;   et al. | 2009-06-18 |
Spirocyclic cyclohexane compounds Grant 7,547,707 - Hinze , et al. June 16, 2 | 2009-06-16 |
Spirocyclic Cyclohexane Compounds Useful To Treat Substance Dependency App 20080221141 - FRIDERICHS; Elmar ;   et al. | 2008-09-11 |
Mixed ORL1/mu-agonists for the treatment of pain App 20080125475 - LINZ; KLAUS ;   et al. | 2008-05-29 |
Spirocyclic cyclohexane compounds Grant 7,332,519 - Hinze , et al. February 19, 2 | 2008-02-19 |
Spirocyclic cyclohexane compounds App 20060004034 - Hinze; Claudia ;   et al. | 2006-01-05 |
Spirocyclic cyclohexane compounds App 20050192333 - Hinze, Claudia ;   et al. | 2005-09-01 |