Patent | Date |
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Process For Manufacturing Alkyl 7-amino-5-methyl- [1,2,5]oxadiazolo[3,4-b]pyridine-carboxylate App 20210363156 - LINZ; Guenter ;   et al. | 2021-11-25 |
Substituted naphthyridines and their use as medicaments Grant 9,187,478 - Hoffmann , et al. November 17, 2 | 2015-11-17 |
Substituted Naphthyridines And Their Use As Medicaments App 20150126503 - HOFFMANN; Matthias ;   et al. | 2015-05-07 |
Substituted naphthyridines and their use as medicaments Grant 8,969,568 - Hoffmann , et al. March 3, 2 | 2015-03-03 |
Selective synthesis of functionalized pyrimidines Grant 8,933,227 - Linz , et al. January 13, 2 | 2015-01-13 |
Regioselective Preparation Of 2-amino-5-trifluoromethylpyrimidine Derivatives App 20140213787 - LINZ; Guenter ;   et al. | 2014-07-31 |
Process for the preparation of acylguanidines and acylthioureas Grant 8,791,260 - Kley , et al. July 29, 2 | 2014-07-29 |
Regioselective preparation of 2-amino-5-trifluoromethylpyrimidine derivatives Grant 8,729,265 - Linz , et al. May 20, 2 | 2014-05-20 |
Specific salt, anhydrous and crystalline form of a dihydropteridione derivative Grant 8,664,222 - Linz , et al. March 4, 2 | 2014-03-04 |
Novel Process For The Preparation Of Acylguanidines And Acylthioureas App 20140039189 - KLEY; Joerg ;   et al. | 2014-02-06 |
Method of preparing chiral cyclic .beta.-aminocarboxamides Grant 8,466,318 - Linz , et al. June 18, 2 | 2013-06-18 |
Novel Process For The Preparation Of Acylguanidines And Acylthioureas App 20130109856 - KLEY; Joerg ;   et al. | 2013-05-02 |
Regioselective Preparation Of Substituted Pyrimidines App 20130079518 - LINZ; Guenter ;   et al. | 2013-03-28 |
Regioselective preparation of substituted pyrimidines Grant 8,372,974 - Linz , et al. February 12, 2 | 2013-02-12 |
Dihydropteridinones, method for production and use thereof App 20120329803 - Linz; Guenter ;   et al. | 2012-12-27 |
Crystalline form of the free base N-[trans-4-[4-(cyclopropylmethyl)-1-piperazinyl]cyclohexyl]-4-[[(7r)-7-et- hyl-5,6,7,8-tetrahydro-5-methyl-8-(1-methylethyl)-6-oxo-2-pteridinyl]amino- ]-3-methoxy-benzamide Grant 8,329,695 - Linz , et al. December 11, 2 | 2012-12-11 |
Process for the manufacture of an indolinone derivative Grant 8,304,541 - Merten , et al. November 6, 2 | 2012-11-06 |
Specific Salt, Anhydrous And Crystalline Form Of A Dihydropteridione Derivative App 20120214995 - Linz; Guenter ;   et al. | 2012-08-23 |
Regioselective Preparation Of 2-amino-5-trifluoromethylpyrimidine Derivatives App 20120172596 - Linz; Guenter ;   et al. | 2012-07-05 |
Methods of using hydrates and polymorphs of 4-[[(7R)-8-cyclopentyl-7-ethyl-5,6,7,8-tetrahydro-5-methyl-6-oxo-2-pterid- inyl]amino]-3-methoxy-N-(1-methyl-4-piperidinyl)-benzamide Grant 8,202,867 - Linz , et al. June 19, 2 | 2012-06-19 |
Specific salt, anhydrous and crystalline form of a dihydropteridione derivative Grant 8,188,086 - Linz , et al. May 29, 2 | 2012-05-29 |
Process for the manufacture of dihydropteridinones Grant 8,138,373 - Linz , et al. March 20, 2 | 2012-03-20 |
Intermediate compounds useful for the manufacture of dihydropteridinones Grant 8,138,341 - Linz , et al. March 20, 2 | 2012-03-20 |
Substituted Naphthyridines And Their Use As Medicaments App 20120028939 - Hoffmann; Matthias ;   et al. | 2012-02-02 |
Process for the manufacture of fused piperazin-2-one derivatives Grant RE43,115 - Duran , et al. January 17, 2 | 2012-01-17 |
Hydrates and polymorphs of 4-[[(7R)-8-cyclopentyl-7-ethyl-5,6,7,8-tetrahydro-5-methyl-6-oxo-2-pterid- inyl]amino]-3-methoxy-N-(1-methyl-4-piperidinyl)-benzamide, process for their manufacture and their use as medicament Grant 8,034,816 - Linz , et al. October 11, 2 | 2011-10-11 |
Process For The Manufacture Of An Indolinone Derivative App 20110201812 - Merten; Joern ;   et al. | 2011-08-18 |
Selective Synthesis Of Functionalized Pyrimidines App 20110190499 - LINZ; Guenter ;   et al. | 2011-08-04 |
Regioselective Preparation Of Substituted Pyrimidines App 20110060141 - Linz; Guenter ;   et al. | 2011-03-10 |
Crystalline Form Of A Dihydropteridione Derivative App 20100280037 - Linz; Guenter ;   et al. | 2010-11-04 |
Process for the manufacture of dihydropteridinones App 20100249412 - LINZ; Guenter ;   et al. | 2010-09-30 |
Process for the manufacture of dihydropteridinones App 20100249458 - LINZ; Guenter ;   et al. | 2010-09-30 |
Process for the manufacture of dihydropteridinones Grant 7,759,485 - Linz , et al. July 20, 2 | 2010-07-20 |
Hydrates and polymorphs of 4[[(7R)-8-cyclopentyl-7-ethyl-5,6,7,8-tetrahydro-5-methyl-6-oxo-2-pteridi- nyl]amino]-3-methoxy-N-(1-methyl-4-piperidinyl)-benzamide, process for their manufacture and their use as medicament Grant 7,728,134 - Linz , et al. June 1, 2 | 2010-06-01 |
New Salts and Crystalline Salt Forms of an Indolinone Derivative App 20090318471 - Sieger; Peter ;   et al. | 2009-12-24 |
Methods of Using hydrates and polymorphs of 4-[[(7R)-8-cyclopentyl-7-ethyl-5,6,7,8-tetrahydro-5-methyl-6-oxo-2-pterid- inyl]amino]-3-methoxy-N-(1-methyl-4-piperidinyl)-benzamide App 20090318457 - LINZ; Guenter ;   et al. | 2009-12-24 |
Hydrates and polymorphs of 4-[[(7R)-8-cyclopentyl-7-ethyl-5,6,7,8-tetrahydro-5-methyl-6-oxo-2-pterid- inyl]amino]-3-methoxy-N-(1-methyl-4-piperidinyl)-benzamide, process for their manufacture and their use as medicament App 20090298840 - LINZ; Guenter ;   et al. | 2009-12-03 |
Intermediate compounds for the manufacture of fused piperazin-2-one derivatives Grant 7,626,019 - Duran , et al. December 1, 2 | 2009-12-01 |
Method Of Preparing Chiral Cyclic Beta-aminocarboxamides App 20090209787 - Linz; Guenter ;   et al. | 2009-08-20 |
Indolinone derivatives substituted in the 6 position, the preparation thereof and their use as pharmaceutical compositions Grant 7,514,468 - Heckel , et al. April 7, 2 | 2009-04-07 |
Specific Salt, Anhydrous And Crystalline Form Of A Dihydropteridione Derivative App 20090030004 - Linz; Guenter ;   et al. | 2009-01-29 |
Specific salt, anhydrous and crystalline form of a dihydropteridione derivative Grant 7,439,358 - Linz , et al. October 21, 2 | 2008-10-21 |
Process for the manufacture of dihydropteridinones App 20080177066 - Linz; Guenter ;   et al. | 2008-07-24 |
(R)-2-(4-amidinophenylaminomethyl)-1-methyl-5-[1-(carboxymethylamino)-1- (pyrrolidinocarbonyl)-ethyl]-benzimidazole, the monohydrochloride thereof, preparation thereof and the use as pharmaceutical composition App 20080076934 - Linz; Guenter ;   et al. | 2008-03-27 |
(R)-2-(4-amidinophenylaminomethyl)-1-methyl-5-[1-(carboxymethylamino)-1(py- rrolidinocarbonyl)-ethyl]-benzimidazole, the monohydrochloride thereof, preparation thereof and the use as pharmaceutical composition Grant 7,294,721 - Linz , et al. November 13, 2 | 2007-11-13 |
Process for the Manufacture of fused piperazin-2-one derivatives App 20070219369 - Duran; Adil ;   et al. | 2007-09-20 |
Process for the Manufacture of fused piperazin-2-one derivatives App 20070213531 - DURAN; Adil ;   et al. | 2007-09-13 |
Process for the Manufacture of fused piperazin-2-one derivatives App 20070213534 - DURAN; Adil ;   et al. | 2007-09-13 |
Process for the Manufacture of fused piperazin-2-one derivatives App 20070213529 - DURAN; Adil ;   et al. | 2007-09-13 |
Intermediate Compounds for the Manufacture of fused piperazin-2-one derivatives App 20070213530 - Duran; Adil ;   et al. | 2007-09-13 |
Process for the Manufacture of Fused piperazin-2-one derivatives App 20070213528 - DURAN; Adil ;   et al. | 2007-09-13 |
Intermediate compounds for the manufacture of fused piperazin-2-one derivatives App 20070208027 - DURAN; Adil ;   et al. | 2007-09-06 |
Specific Salt, Anhydrous And Crystalline Form Of A Dihydropteridione Derivative App 20070203146 - Linz; Guenter ;   et al. | 2007-08-30 |
Process for the manufacture of fused piperazin-2-one derivatives Grant 7,238,807 - Duran , et al. July 3, 2 | 2007-07-03 |
(R)-2-(4-amidinophenylaminomethyl)-1-methyl-5-[1-(carboxymethylamino)-1(py- rrolidinocarbonyl)-ethyl]-benzimidazole, the monohydrochloride thereof, preparation thereof and the use as pharmaceutical composition App 20070099974 - Linz; Guenter ;   et al. | 2007-05-03 |
(R) 2-(4-amidinophenylaminomethyl)-1-methyl-5-[1-(carboxymethylamino)-1 (pyrrolidinocarbonyl)-ethyl]-benzimidazole, the monohydrochloride thereof, preparation thereof and the use as pharmaceutical composition Grant 7,169,934 - Linz , et al. January 30, 2 | 2007-01-30 |
3-Z-[1-(4-(N-((4-Methyl-piperazin-1-yl)-methylcarbonyl)-N-methyl-amino)-an- ilino)-1-phenyl-methylene]-6-methoxycarbonyl-2-indolinone-monoethanesulpho- nate and the use thereof as a pharmaceutical composition App 20060258681 - Roth; Gerald J. ;   et al. | 2006-11-16 |
3-Z-[1-(4-(N-((4-Methyl-piperazin-1-yl)-methylcarbonyl)-N-methyl-amino)-an- ilino)-1-phenyl-methylene]-6-methoxycarbonyl-2-indolinone-monoethanesulpho- nate and the use thereof as a pharmaceutical composition Grant 7,119,093 - Roth , et al. October 10, 2 | 2006-10-10 |
Indolinone derivatives substituted in the 6 position, the preparation thereof and their use as pharmaceutical compositions App 20060194813 - Heckel; Armin ;   et al. | 2006-08-31 |
Process for the manufacture of fused piperazin-2-one derivatives App 20060122393 - Duran; Adil ;   et al. | 2006-06-08 |
Hydrates and polymorphs of 4-[[(7R)-8-cyclopentyl-7-ethyl-5,6,7,8-tetrahydro-5-methyl-6-oxo-2-pterid- inyl]amino]-3-methoxy-N-(1-methyl-4-piperidinyl)-benzamide, process for their manufacture and their use as medicament App 20060035902 - Linz; Guenter ;   et al. | 2006-02-16 |
Pharmaceutical compositions containing tiotropium salts and low-solubility salmeterol salts App 20050256149 - Linz, Guenter ;   et al. | 2005-11-17 |
Process for preparing 1- [N-[3,5-dibromo-N-[[4-(3,4-dihydro-2(1H)-oxoquina- zolin-3-yl)-1-piperidinyl]carbonyl]-D-tyrosyl]-L-lysyl]-4-(4-pyridinyl)-pi- perazine App 20050192230 - Linz, Guenter ;   et al. | 2005-09-01 |
Pharmaceutical compositions containing tiotropium salts and low-solubility salmeterol salts Grant 6,919,325 - Linz , et al. July 19, 2 | 2005-07-19 |
3-Z-[1-(4-(N-((4-methyl-piperazin-1-yl)-methylcarbonyl)-N-methyl-amino)-an- ilino)-1-phenyl-methylene]-6-methoxycarbonyl-2-indolinone-monoethanesulpho- nate and the use thereof as a pharmaceutical composition App 20040176392 - Roth, Gerald J. ;   et al. | 2004-09-09 |
Cinnamic acid salts, processes for their preparation, and their use as medicaments Grant 6,756,508 - Linz , et al. June 29, 2 | 2004-06-29 |
Salicylic acid salts of salmeterol Grant 6,680,345 - Linz , et al. January 20, 2 | 2004-01-20 |
(R) 2-(4-amidinophenylaminomethyl)-1-methyl-5-[1-(carboxymethylamino)-1 (pyrrolidinocarbonyl)-ethyl]-benzimidazole, the monohydrochloride thereof, preparation thereof and the use as pharmaceutical composition App 20040010026 - Linz, Guenter ;   et al. | 2004-01-15 |
Cinnamaic acid salts, processes for the preparation thereof and use thereof as medicament App 20030166722 - Linz, Guenter ;   et al. | 2003-09-04 |
Pharmaceutical compositions containing tiotropium salts and low-solubility salmeterol salts App 20030130300 - Linz, Guenter ;   et al. | 2003-07-10 |
Salicylic acid salts of salmeterol App 20030069310 - Linz, Guenter ;   et al. | 2003-04-10 |
Cyclic imino derivatives and pharmaceutical compositions containing them Grant 5,591,769 - Himmelsbach , et al. January 7, 1 | 1997-01-07 |
Cyclic imino derivatives and pharmaceutical compositions containing them Grant 5,541,343 - Himmelsbach , et al. July 30, 1 | 1996-07-30 |
Cyclic urea derivatives and pharmaceutical compositions containing these compounds Grant 5,478,942 - Himmelsbach , et al. December 26, 1 | 1995-12-26 |
5-membered heterocyclic compounds, processes for preparing them and pharmaceutical compositions containing these compounds Grant 5,463,071 - Himmelsbach , et al. October 31, 1 | 1995-10-31 |
2-pyrrolidinones, pharmaceutical compositions containing these compounds and processes for preparing them Grant 5,455,348 - Austel , et al. October 3, 1 | 1995-10-03 |
Condensed 5-membered heterocyclic compounds, processes for preparing them and pharmaceutical preparations containing these compounds Grant 5,434,150 - Austel , et al. July 18, 1 | 1995-07-18 |
Heterobiarly derivatives and pharmaceutical compositions thereof Grant 5,418,233 - Linz , et al. May 23, 1 | 1995-05-23 |
Cyclic urea derivatives, pharmaceutical compositions containing these compounds and methods of using the same Grant 5,276,049 - Himmelsbach , et al. January 4, 1 | 1994-01-04 |