Patent | Date |
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Monoclonal antibodies to progastrin and their uses Grant 11,299,542 - Pannequin , et al. April 12, 2 | 2022-04-12 |
5-[(piperazin-l-yl)-3-oxo-propyl]-imidazolidine-2,4-dione derivatives as ADAMTS inhibitors for the treatment of osteoarthritis Grant 10,941,117 - Brebion , et al. March 9, 2 | 2021-03-09 |
Combination of a MCL-1 inhibitor and a taxane compound, uses and pharmaceutical compositions thereof Grant 10,765,680 - Porter , et al. Sep | 2020-09-08 |
Hydroxyester derivatives, a process for their preparation and pharmaceutical compositions containing them Grant 10,711,010 - Szlavik , et al. | 2020-07-14 |
Pyrrole compounds, a process for their preparation and pharmaceutical compositions containing them Grant 10,688,101 - Le Tiran , et al. | 2020-06-23 |
Methods and compositions for liver cancer therapy Grant 10,533,050 - Houhou , et al. Ja | 2020-01-14 |
Indolizine compounds, a process for their preparation and pharmaceutical compositions containing them Grant 10,258,626 - Le Diguarher , et al. | 2019-04-16 |
5-[(piperazin-1-yl)-3-oxo-propyl]-imidazolidine-2,4-dione derivatives as ADAMTS inhibitors for the treatment of osteoarthritis Grant 9,926,281 - Brebion , et al. March 27, 2 | 2018-03-27 |
Process for the synthesis of 7-methoxy-naphthalene-1-carbaldehyde and application in the synthesis of agomelatine Grant 9,701,608 - Briere , et al. July 11, 2 | 2017-07-11 |
Process for the enzymatic synthesis of (7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-triene-7-carboxylic acid or esters thereof, and application in the synthesis of ivabradine and salts thereof Grant 9,506,095 - Pedragosa-Moreau , et al. November 29, 2 | 2016-11-29 |
Methods for treating pancreatic cancer Grant 9,487,582 - Houhou , et al. November 8, 2 | 2016-11-08 |
Complexes Of Agomelatine And Sulphonic Acids, A Process For Their Preparation And Pharmaceutical Compositions Containing Them App 20160159735 - SHAN; Hanbin ;   et al. | 2016-06-09 |
Synthesis process, and crystalline form of 4-{3-[cis-hexahydrocyclopenta[c]pyrrol-2(1H)-yl]propoxy} benzamide hydrochloride and pharmaceutical compositions containing it Grant 8,952,179 - Robert , et al. February 10, 2 | 2015-02-10 |
Administration Regime For N-hydroxy-4-benzamide App 20150024040 - Kloos; Ioana ;   et al. | 2015-01-22 |
Process for the resolution of enantiomers of (3,4 dimethoxy-bicyclo[4.2.0]octa-1,3,5-trien-7-yl)nitrile and application in the synthesis of ivabradine Grant 8,927,758 - Lerestif , et al. January 6, 2 | 2015-01-06 |
Progastrin and liver pathologies Grant 8,900,817 - Floch , et al. December 2, 2 | 2014-12-02 |
Methods for treating breast cancer Grant 8,900,588 - Floch , et al. December 2, 2 | 2014-12-02 |
Process for the synthesis of agomelatine Grant 8,871,975 - Zard , et al. October 28, 2 | 2014-10-28 |
Process for the resolution of enantiomers of (3,4-dimethoxy-bicyclo[4.2.0]octa-1,3,5-trien-7-yl)nitrile and application in the synthesis of ivabradine Grant 8,778,930 - Lerestif , et al. July 15, 2 | 2014-07-15 |
Mixed Crystal Agomelatine (form Viii), Preparation Method And Use Thereof And Pharmaceutical Composition Containing Same App 20140088197 - Huang; Yu ;   et al. | 2014-03-27 |
Polymerized micelles Grant 8,663,660 - Ogier , et al. March 4, 2 | 2014-03-04 |
Crystalline form VI of agomelatine, preparation method and application thereof Grant 8,614,251 - Shan , et al. December 24, 2 | 2013-12-24 |
Agomelatine Intermediates And Preparation Method Thereof App 20130267738 - Zhang; Peng ;   et al. | 2013-10-10 |
Agomelatine hydrohalide complex and preparation method thereof Grant 8,524,949 - Shan , et al. September 3, 2 | 2013-09-03 |
Benzothiadiazepine compounds, a process for their preparation and pharmaceutical compositions containing them Grant 8,236,790 - Cordi , et al. August 7, 2 | 2012-08-07 |
Indole compounds, a process for their preparation and pharmaceutical compositions containing them Grant 8,003,682 - Marchand , et al. August 23, 2 | 2011-08-23 |
Process for the synthesis of (7-methoxy-1-naphthyl) acetonitrile and its application in the synthesis of agomelatine Grant 7,999,129 - Souvie , et al. August 16, 2 | 2011-08-16 |
Pharmaceutical composition comprising a strontium salt, vitamin D and A cyclodextrin App 20110130370 - Briault; Gilles ;   et al. | 2011-06-02 |
Use of agomelatine in obtaining medicaments intended for the treatment of bipolar disorders Grant 7,947,743 - De Bodinat , et al. May 24, 2 | 2011-05-24 |
Peptides which interact with anti-apoptotic members of the Bcl-2 protein family, and uses Grant 7,927,813 - Geneste , et al. April 19, 2 | 2011-04-19 |
.gamma.-crystalline form of ivabradine hydrochloride, a process for its preparation and pharmaceutical compositions containing it Grant 7,867,996 - Horvath , et al. January 11, 2 | 2011-01-11 |
Crystalline form III of agomelatine, a process for its preparation and pharmaceutical compositions containing it App 20100063158 - Coquerel; Gerard ;   et al. | 2010-03-11 |
Process for the synthesis of perindopril and its pharmaceutically acceptable salts Grant 7,534,896 - Dubuffet , et al. May 19, 2 | 2009-05-19 |
4-oxo-4,6,7,8-tetrahydro-pyrrolo[1,2-a]pyrazine-6-carboxamide compounds Grant 7,498,330 - De Nanteuil , et al. March 3, 2 | 2009-03-03 |
Process for the synthesis of (7-methoxy-1-naphthyl) acetonitrile and its application in the synthesis of agomelatine Grant 7,470,806 - Souvie , et al. December 30, 2 | 2008-12-30 |
Peptide interacting with anti-apoptotic proteins of the Bcl-2 family Grant 7,459,434 - Geneste , et al. December 2, 2 | 2008-12-02 |
Polysubstituted 1,1-pyridylaminocyclopropanamine compounds App 20080146621 - Goldstein; Solo ;   et al. | 2008-06-19 |
Method for the synthesis of perindopril and the pharmaceutically acceptable salts thereof Grant 7,368,580 - Fugier , et al. May 6, 2 | 2008-05-06 |
Method for the synthesis of perindopril and the pharmaceutically acceptable salts thereof Grant 7,358,372 - Fugier , et al. April 15, 2 | 2008-04-15 |
Crystalline form V of agomelatine, a process for its preparation and pharmaceutical compositions containing it Grant 7,358,395 - Coquerel , et al. April 15, 2 | 2008-04-15 |
Process for the synthesis of (2S)-indoline-2-carboxylic acid Grant 7,323,575 - Souvie , et al. January 29, 2 | 2008-01-29 |
Substituted benzo[e][1,4]oxazino[3,2-g]isoindole compounds Grant 7,312,213 - Coudert , et al. December 25, 2 | 2007-12-25 |
Amino acid derivatives, method for production thereof and pharmaceutical compositions comprising said derivative Grant 7,265,220 - De Nanteuil , et al. September 4, 2 | 2007-09-04 |
Benzothiadiazine compounds Grant 7,262,191 - Desos , et al. August 28, 2 | 2007-08-28 |
Method for synthesising perindopril and the pharmaceutically acceptable salt thereof Grant 7,166,633 - Dubuffet , et al. January 23, 2 | 2007-01-23 |
[3,4-a:3,4-c]carbazole compounds Grant 7,151,108 - Prudhomme , et al. December 19, 2 | 2006-12-19 |
New substituted pyridine or piperidine compounds App 20060211731 - Meth-Cohn; Otto ;   et al. | 2006-09-21 |
Process for the synthesis of 1,3-dihydro-2H-3-benzazepin-2-one compounds, and to the application thereof in the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid Grant 7,074,920 - Lerestif , et al. July 11, 2 | 2006-07-11 |
Octahydro-2H-pyrido[1,2-a]pyrazine compounds Grant 6,992,085 - Goldstein , et al. January 31, 2 | 2006-01-31 |
Beta crystalline form of perindopril tert-butylamine salt App 20050203165 - Pfeiffer, Bruno ;   et al. | 2005-09-15 |
1,1- and 1,2-disubstituted cyclopropane compounds Grant 6,943,184 - Goldstein , et al. September 13, 2 | 2005-09-13 |
Imidazoline compounds App 20050143440 - Rault, Sylvain ;   et al. | 2005-06-30 |
Linear cyclic ureas Grant 6,903,103 - Peglion , et al. June 7, 2 | 2005-06-07 |
Substituted cyclic compounds, preparation method and pharmaceutical compositions containing them Grant 6,872,851 - Lesieur , et al. March 29, 2 | 2005-03-29 |
Vitronectin receptor antagonist bicyclic compounds, preparation method and compositions containing same Grant 6,846,833 - Casara , et al. January 25, 2 | 2005-01-25 |
Core tablet for controlled release of gliclazide after oral administration Grant 6,733,782 - Huet De Barochez , et al. May 11, 2 | 2004-05-11 |
Amino acid derivatives and use thereof as NEP, ACE and ECE inhibitors Grant 6,716,852 - Roques , et al. April 6, 2 | 2004-04-06 |
Alpha-amino-acid compounds Grant 6,706,742 - De Nanteuil , et al. March 16, 2 | 2004-03-16 |
Benzo[b]pyrano[3,2-h]acridin-7-one compounds Grant 6,642,248 - Koch , et al. November 4, 2 | 2003-11-04 |
Substituted heterocyclic compounds Grant 6,602,903 - Guillaumet , et al. August 5, 2 | 2003-08-05 |