Leake; Devin
Patent Applications and Registrations
Patent applications and USPTO patent grants for Leake; Devin.The latest application filed is for "systems and methods for storing and reading nucleic acid-based data with error protection".
Company Profile
22.153.200
- Leake; Devin - Charlestown MA
- Leake; Devin - Boston MA
- Leake; Devin - Denver CO
- Leake; Devin - Lexington MA
- Leake; Devin - Boulder CO
Patent Activity
| Patent | Date |
|---|---|
| Printer-finisher system for data storage in DNA Grant 11,305,527 - Roquet , et al. April 19, 2 | 2022-04-19 |
| Chemical methods for nucleic acid-based data storage Grant 11,286,479 - Leake , et al. March 29, 2 | 2022-03-29 |
| Compositions and methods for nucleic acid-based data storage Grant 11,227,219 - Roquet , et al. January 18, 2 | 2022-01-18 |
| Methods and compositions for selecting siRNA of improved functionality Grant 11,198,870 - Khvorova , et al. December 14, 2 | 2021-12-14 |
| Systems And Methods For Storing And Reading Nucleic Acid-based Data With Error Protection App 20210210165 - Leake; Devin ; et al. | 2021-07-08 |
| Compositions And Methods For Nucleic Acid-based Data Storage App 20210209479 - Roquet; Nathaniel ; et al. | 2021-07-08 |
| Printer-finisher System For Data Storage In Dna App 20210187944 - Roquet; Nathaniel ; et al. | 2021-06-24 |
| Nucleic Acid Security And Authentication App 20210108194 - Roquet; Nathaniel ; et al. | 2021-04-15 |
| Chemical Methods For Nucleic Acid-based Data Storage App 20210079382 - Leake; Devin ; et al. | 2021-03-18 |
| siRNA targeting LDHA Grant 10,920,226 - Khvorova , et al. February 16, 2 | 2021-02-16 |
| Methods and compositions for selecting siRNA of improved functionality Grant 10,765,695 - Khvorova , et al. Sep | 2020-09-08 |
| Methods and Compositions for Selecting siRNA of Improved Functionality App 20200270607 - Khvorova; Anastasia ; et al. | 2020-08-27 |
| Methods and compositions for selecting siRNA of improved functionality Grant 10,696,968 - Khvorova , et al. June 30, 2 | 2020-06-30 |
| Compositions And Methods For Nucleic Acid-based Data Storage App 20200193301 - Roquet; Nathaniel ; et al. | 2020-06-18 |
| Systems And Methods For Storing And Reading Nucleic Acid-based Data With Error Protection App 20200185057 - Leake; Devin ; et al. | 2020-06-11 |
| Compositions And Methods For Site-directed Dna Nicking And Cleaving App 20200181591 - Jacobson; Joseph ; et al. | 2020-06-11 |
| siRNA Targeting LDHA App 20200123550 - Khvorova; Anastasia ; et al. | 2020-04-23 |
| Device And Method For Nucleic Acid Manipulation App 20200095705 - Jacobson; Joseph ; et al. | 2020-03-26 |
| Printer-finisher System For Data Storage In Dna App 20190351673 - Roquet; Nathaniel ; et al. | 2019-11-21 |
| Methods and Compositions for Selecting siRNA of Improved Functionality App 20190345573 - Khvorova; Anastasia ; et al. | 2019-11-14 |
| Methods and Compositions for Selecting siRNA of Improved Functionality App 20190316139 - Khvorova; Anastasia ; et al. | 2019-10-17 |
| Methods and compositions for selecting siRNA of improved functionality Grant 10,421,970 - Khvorova , et al. Sept | 2019-09-24 |
| Methods and Compositions for Selecting siRNA of Improved Functionality App 20190270995 - Khvorova; Anastasia ; et al. | 2019-09-05 |
| METHODS AND COMPOSITIONS FOR SELECTING siRNA OF IMPROVED FUNCTIONALITY App 20190233829 - Khvorova; Anastasia ; et al. | 2019-08-01 |
| siRNA Targeting LDHA App 20190106699 - Khvorova; Anastasia ; et al. | 2019-04-11 |
| Methods and compositions for selecting siRNA of improved functionality Grant 10,233,449 - Khvorova , et al. | 2019-03-19 |
| Methods and Compositions for Selecting siRNA of Improved Functionality App 20180320182 - Khvorova; Anastasia ; et al. | 2018-11-08 |
| Methods and Compositions for Selecting siRNA of Improved Functionality App 20180214474 - Khvorova; Anastasia ; et al. | 2018-08-02 |
| Methods and Compositions for Selecting siRNA of Improved Functionality App 20180201934 - Khvorova; Anastasia ; et al. | 2018-07-19 |
| Methods and compositions for selecting siRNA of improved functionality Grant 10,011,836 - Khvorova , et al. July 3, 2 | 2018-07-03 |
| Templates, libraries, kits and methods for generating molecules Grant 9,988,625 - Leake , et al. June 5, 2 | 2018-06-05 |
| METHODS AND COMPOSITIONS FOR SELECTING siRNA OF IMPROVED FUNCTIONALITY App 20180119144 - Khvorova; Anastasia ; et al. | 2018-05-03 |
| Methods and compositions for selecting siRNA of improved functionality Grant 9,879,266 - Khvorova , et al. January 30, 2 | 2018-01-30 |
| Methods and compositions for selecting siRNA of improved functionality Grant 9,839,649 - Khvorova , et al. December 12, 2 | 2017-12-12 |
| Methods and Compositions for Selecting siRNA of Improved Functionality App 20170349904 - Khvorova; Anastasia ; et al. | 2017-12-07 |
| Methods and compositions for selecting siRNA of improved functionality Grant 9,777,270 - Khvorova , et al. October 3, 2 | 2017-10-03 |
| RNAi targeting ZNF205 Grant 9,771,586 - Khvorova , et al. September 26, 2 | 2017-09-26 |
| RNAi targeting CNTD2 Grant 9,719,092 - Khvorova , et al. August 1, 2 | 2017-08-01 |
| RNAi targeting SEC61G Grant 9,719,094 - Khvorova , et al. August 1, 2 | 2017-08-01 |
| Compositions and Methods for Site-Directed DNA Nicking and Cleaving App 20170198268 - Jacobson; Joseph ; et al. | 2017-07-13 |
| RNAi Targeting CNTD2 App 20160369278 - Khvorova; Anastasia ; et al. | 2016-12-22 |
| RNAi Targeting SEC61G App 20160369284 - Khvorova; Anastasia ; et al. | 2016-12-22 |
| RNAi Targeting ZNF205 App 20160369276 - Khvorova; Anastasia ; et al. | 2016-12-22 |
| Methods and Compositions for Selecting siRNA of Improved Functionality App 20160201065 - Khvorova; Anastasia ; et al. | 2016-07-14 |
| METHODS AND COMPOSITIONS FOR SELECTING siRNA OF IMPROVED FUNCTIONALITY App 20160201058 - Khvorova; Anastasia ; et al. | 2016-07-14 |
| Methods and Compositions for Selecting siRNA of Improved Functionality App 20160193242 - Khvorova; Anastasia ; et al. | 2016-07-07 |
| Methods and Compositions for Selecting siRNA of Improved Functionality App 20160194646 - Khvorova; Anastasia ; et al. | 2016-07-07 |
| Methods and compositions for selecting siRNA of improved functionality Grant 9,228,186 - Khvorova , et al. January 5, 2 | 2016-01-05 |
| Templates, Libraries, Kits and Methods for Generating Molecules App 20150353927 - Leake; Devin ; et al. | 2015-12-10 |
| siRNA targeting catenin, beta-1 (CTNNB1) Grant 8,937,172 - Khvorova , et al. January 20, 2 | 2015-01-20 |
| siRNA targeting TIE-2 Grant 8,907,077 - Khvorova , et al. December 9, 2 | 2014-12-09 |
| siRNA targeting myeloid differentiation primary response gene (88) (MYD88) Grant 8,883,998 - Khvorava , et al. November 11, 2 | 2014-11-11 |
| Tripartite oligonucleotide complexes and methods for gene silencing by RNA interference Grant 8,809,514 - Yamada , et al. August 19, 2 | 2014-08-19 |
| siRNA Targeting Catenin, Beta-1 (CTNNB1) App 20140228251 - Khvorova; Anastasia ; et al. | 2014-08-14 |
| Methods and Compositions for Selecting siRNA of Improved Functionality App 20140148362 - Khvorova; Anastasia ; et al. | 2014-05-29 |
| siRNA Targeting TIE-2 App 20140094390 - Khvorova; Anastasia ; et al. | 2014-04-03 |
| Modulators of Protein Production in a Human Cell Line and Cell-free Extracts Produced Therefrom App 20140066595 - Anderson; Emily ; et al. | 2014-03-06 |
| siRNA targeting tie-2 Grant 8,658,785 - Khvorova , et al. February 25, 2 | 2014-02-25 |
| siRNA targeting amyloid beta (A4) precursor protein (APP) Grant 8,658,784 - Khvorova , et al. February 25, 2 | 2014-02-25 |
| SiRNA targeting histamine receptor H1 Grant 8,633,306 - Khvorova , et al. January 21, 2 | 2014-01-21 |
| Methods of modulating mesenchymal stem cell differentiation Grant 8,580,757 - Federov , et al. November 12, 2 | 2013-11-12 |
| siRNA targeting kinase insert domain receptor (KDR) Grant 8,575,329 - Khvorova , et al. November 5, 2 | 2013-11-05 |
| siRNA Targeting Apolipoprotein B (APOB) App 20130225447 - Khvorova; Anastasia ; et al. | 2013-08-29 |
| siRNA Targeting Cyclin-dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B) App 20130225667 - Khvorova; Anastasia ; et al. | 2013-08-29 |
| siRNA Targeting Myeloid Differentiation Primary Response Gene (88) (MYD88) App 20130210676 - Khvorova; Anastasia ; et al. | 2013-08-15 |
| Duplex oligonucleotide complexes and methods for gene silencing by RNA interference Grant 8,501,706 - Yamada , et al. August 6, 2 | 2013-08-06 |
| SiRNA targeting connective tissue growth factor (CTGF) Grant 8,461,326 - Khvorova , et al. June 11, 2 | 2013-06-11 |
| SiRNA targeting cyclin-dependent kinase inhibitor 1B (p27, Kip1) (CDKN1B) Grant 8,445,667 - Khvorova , et al. May 21, 2 | 2013-05-21 |
| SiRNA targeting apolipoprotein (APOB) Grant 8,445,668 - Khvorova , et al. May 21, 2 | 2013-05-21 |
| SiRNA targeting myeloid differentiation primary response gene (88) (MYD88) Grant 8,426,579 - Khvorova , et al. April 23, 2 | 2013-04-23 |
| Duplex oligonucleotides with enhanced functionality in gene regulation Grant 8,415,466 - Khvorova , et al. April 9, 2 | 2013-04-09 |
| siRNA targeting catenin, Beat-1 (CTNNB1) Grant 8,399,654 - Khvorova , et al. March 19, 2 | 2013-03-19 |
| siRNA Targeting Fructose-1, 6-bisphosphatase 1 (FBP1) App 20130059760 - Khvorova; Anastasia ; et al. | 2013-03-07 |
| Dye Blends App 20130052650 - Kavanagh; Ian ; et al. | 2013-02-28 |
| Screening of micro-RNA cluster inhibitor pools Grant 8,367,318 - Smith , et al. February 5, 2 | 2013-02-05 |
| siRNA Targeting Beta Secretase (BACE) App 20130023446 - Khvorova; Anastasia ; et al. | 2013-01-24 |
| Duplex Oligonucleotide Complexes and Methods for Gene Silencing by RNA Interference App 20120322855 - Yamada; Christina ; et al. | 2012-12-20 |
| siRNA targeting tie-2 Grant 8,314,229 - Khvorova , et al. November 20, 2 | 2012-11-20 |
| siRNA Targeting Amyloid Beta (A4) Precursor Protein (APP) App 20120283142 - Khvorova; Anastasia ; et al. | 2012-11-08 |
| siRNA Targeting Glucagon Receptor (GCCR) App 20120283311 - Khvorova; Anastasia ; et al. | 2012-11-08 |
| SiRNA targeting fructose-1, 6-bisphosphatase 1 (FBP1) Grant 8,304,528 - Khvorova , et al. November 6, 2 | 2012-11-06 |
| siRNA Targeting Diacylglycerol O-Acyltransferase Homolog 2 (DGAT2) App 20120270751 - Khvorova; Anastasia ; et al. | 2012-10-25 |
| siRNA Targeting Apoliprotein (APOB) App 20120270926 - Khvorova; Anastasia ; et al. | 2012-10-25 |
| SiRNA targeting beta secretase (BACE) Grant 8,293,887 - Khvorova , et al. October 23, 2 | 2012-10-23 |
| siRNA Targeting Cyclin-dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B) App 20120264813 - Khvorova; Anastasia ; et al. | 2012-10-18 |
| siRNA Targeting Proto-oncogene MET App 20120258888 - Khvorova; Anastasia ; et al. | 2012-10-11 |
| siRNA Targeting Kinase Insert Domain Receptor (KDR) App 20120258889 - Khvorova; Anastasia ; et al. | 2012-10-11 |
| Duplex Oligonucleotides with Enhanced Functionality in Gene Regulation App 20120259001 - Khvorova; Anastasia ; et al. | 2012-10-11 |
| siRNA Targeting Interleukin-1 Receptor-associated Kinase 4 (IRAK4) App 20120252873 - Khvorova; Anastasia ; et al. | 2012-10-04 |
| siRNA targeting amyloid beta (A4) precursor protein (APP) Grant 8,268,985 - Khvorova , et al. September 18, 2 | 2012-09-18 |
| siRNA Targeting Catenin, Beta-1 (CTNNB1) App 20120220496 - Khvorova; Anastasia ; et al. | 2012-08-30 |
| Duplex oligonucleotide complexes and methods for gene silencing by RNA interference Grant 8,252,755 - Yamada , et al. August 28, 2 | 2012-08-28 |
| SiRNA targeting diacylglycerol O-acyltransferase homolog 2 (DGAT2) Grant 8,247,169 - Khvorova , et al. August 21, 2 | 2012-08-21 |
| SiRNA targeting glucagon receptor (GCGR) Grant 8,236,942 - Khvorova , et al. August 7, 2 | 2012-08-07 |
| SiRNA targeting apolipoprotein B (APOB) Grant 8,232,386 - Khvorova , et al. July 31, 2 | 2012-07-31 |
| siRNA targeting cyclin-dependent kinase inhibitor 1B (p27, Kip1) (CDKN1B) Grant 8,232,385 - Khvorova , et al. July 31, 2 | 2012-07-31 |
| siRNA Targeting Connective Tissue Growth Factor (CTGF) App 20120184463 - Khvorova; Anastasia ; et al. | 2012-07-19 |
| SiRNA targeting proto-oncogene MET Grant 8,222,396 - Khvorova , et al. July 17, 2 | 2012-07-17 |
| siRNA targeting kinase insert domain receptor (KDR) Grant 8,222,395 - Khvorova , et al. July 17, 2 | 2012-07-17 |
| siRNA targeting interleukin-1 receptor-associated kinase 4(IRAK4) Grant 8,217,162 - Khvorova , et al. July 10, 2 | 2012-07-10 |
| SiRNA targeting catenin, beta-1 (CTNNB1) Grant 8,198,427 - Khvorova , et al. June 12, 2 | 2012-06-12 |
| Sirna Targeting Catenin, Beta-1 (ctnnb1) App 20120136144 - Khvorova; Anastasia ; et al. | 2012-05-31 |
| siRNA targeting spleen tyrosine kinase App 20120135892 - Khvorova; Anastasia ; et al. | 2012-05-31 |
| Duplex oligonucleotides with enhanced functionality in gene regulation Grant 8,188,060 - Khvorova , et al. May 29, 2 | 2012-05-29 |
| siRNA targeting connective tissue growth factor (CTGF) Grant 8,138,329 - Khvorova , et al. March 20, 2 | 2012-03-20 |
| siRNA Targeting Apolipoprotein B (APOB) App 20120065250 - Khvorova; Anastasia ; et al. | 2012-03-15 |
| Methods And Compositions For Selecting Sirna Of Improved Functionality App 20120052487 - Khvorova; Anastasia ; et al. | 2012-03-01 |
| siRNA targeting Superoxide App 20120015850 - Khvorova; Anastasia ; et al. | 2012-01-19 |
| siRNA targeting myeloid differentiation primary response gene (88) (MYD88) App 20120010106 - Khvorova; Anastasia ; et al. | 2012-01-12 |
| siRNA targeting spleen tyrosine kinase Grant 8,093,370 - Khvorova , et al. January 10, 2 | 2012-01-10 |
| Functional and hyperfunctional siRNA Grant 8,090,542 - Khvorova , et al. January 3, 2 | 2012-01-03 |
| siRNA targeting histamine receptor H1 App 20110319296 - Khvorova; Anastasia ; et al. | 2011-12-29 |
| siRNA targeting gremlin App 20110319297 - Khvorova; Anastasia ; et al. | 2011-12-29 |
| siRNA targeting cyclin-dependent kinase 4 (CDK4) App 20110319474 - Khvorova; Anastasia ; et al. | 2011-12-29 |
| siRNA targeting apolipoprotein B (APOB) Grant 8,071,754 - Khvorova , et al. December 6, 2 | 2011-12-06 |
| siRNA targeting serine/threonine kinase 12 (STK12 or aurora B kinase) Grant 8,067,576 - Khvorova , et al. November 29, 2 | 2011-11-29 |
| siRNA targeting beta secretase (BACE) App 20110281769 - Khvorova; Anastasia ; et al. | 2011-11-17 |
| siRNA targeting cyclin-dependent kinase inhibitor 1B (p27, Kip1) (CDKN1B) App 20110269951 - Khvorova; Anastasia ; et al. | 2011-11-03 |
| Methods Of Modulating Mesenchymal Stem Cell Differentiation App 20110263675 - Federov; Yuriy ; et al. | 2011-10-27 |
| siRNA targeting superoxide dismutase 1 (SOD1) Grant 8,039,610 - Khvorova , et al. October 18, 2 | 2011-10-18 |
| siRNA targeting cyclin-dependent kinase 4 (CDK4) Grant 8,030,474 - Khvorova , et al. October 4, 2 | 2011-10-04 |
| siRNA targeting gremlin Grant 8,030,476 - Khvorova , et al. October 4, 2 | 2011-10-04 |
| siRNA targeting histamine receptor H1 Grant 8,022,198 - Khvorova , et al. September 20, 2 | 2011-09-20 |
| SiRNA targeting myeloid differentiation primary response gene (88) (MYD88) Grant 8,022,199 - Khvorova , et al. September 20, 2 | 2011-09-20 |
| SiRNA targeting cyclin-dependent kinase inhibitor 1B (p27, Kip1) (CDKN1B) Grant 8,013,145 - Khvorova , et al. September 6, 2 | 2011-09-06 |
| siRNA targeting KRAS Grant 8,008,474 - Khvorova , et al. August 30, 2 | 2011-08-30 |
| Methods and compositions for selecting siRNA of improved functionality Grant 8,000,902 - Khvorova , et al. August 16, 2 | 2011-08-16 |
| siRNA targeting beta secretase (BACE) Grant 7,999,097 - Khvorova , et al. August 16, 2 | 2011-08-16 |
| siRNA targeting TATA box binding protein (TBP)-associated factor (TAF1) Grant 7,985,854 - Khvorova , et al. July 26, 2 | 2011-07-26 |
| siRNA targeting TNF.alpha. Grant 7,977,471 - Khvorova , et al. July 12, 2 | 2011-07-12 |
| siRNA targeting v-myc myelocytomatosis viral oncogene homolog (MYC) Grant 7,951,935 - Khvorova , et al. May 31, 2 | 2011-05-31 |
| siRNA targeting spleen tyrosine kinase App 20110111983 - Khvorova; Anastasia ; et al. | 2011-05-12 |
| siRNA targeting TNFa App 20110105363 - Khvorova; Anastasia ; et al. | 2011-05-05 |
| siRNA target hypoxia-inducible factor 1 Grant 7,935,813 - Khvorova , et al. May 3, 2 | 2011-05-03 |
| Apparatus and system having dry gene silencing compositions Grant 7,935,811 - Robertson , et al. May 3, 2 | 2011-05-03 |
| Apparatus and system having dry gene silencing pools Grant 7,923,207 - Robertson , et al. April 12, 2 | 2011-04-12 |
| Method of determining a cellular response to a biological agent Grant 7,923,206 - Robertson , et al. April 12, 2 | 2011-04-12 |
| siRNA targeting TIE-2 App 20110077173 - Khvorova; Anastasia ; et al. | 2011-03-31 |
| SiRNA targeting ras-related nuclear protein RAN Grant 7,897,754 - Khvorova , et al. March 1, 2 | 2011-03-01 |
| siRNA targeting spleen tyrosine kinase Grant 7,893,247 - Khvorova , et al. February 22, 2 | 2011-02-22 |
| siRNA targeting connective tissue growth factor (CTGF) App 20110039734 - Khvorova; Anastasia ; et al. | 2011-02-17 |
| siRNA targeting proto-oncogene MET App 20110034349 - Khvorova; Anastasia ; et al. | 2011-02-10 |
| siRNA targeting amyloid beta (A4) precursor protein (APP) App 20110021382 - Khvorova; Anastasia ; et al. | 2011-01-27 |
| siRNA Targeting Beta Secretase (BACE) App 20110003714 - Khvorova; Anastasia ; et al. | 2011-01-06 |
| siRNA targeting apolipoprotein B (APOB) App 20110003713 - Khvorova; Anastasia ; et al. | 2011-01-06 |
| siRNA Targeting Survivin App 20100331214 - Khvorova; Anastasia ; et al. | 2010-12-30 |
| siRNA targeting TATA box binding protein (TBP)-associated factor (TAF1) App 20100323922 - Khvorova; Anastasia ; et al. | 2010-12-23 |
| siRNA targeting TIE-2 Grant 7,855,186 - Khvorova , et al. December 21, 2 | 2010-12-21 |
| Methods and compositions for selecting siRNA of improved functionality App 20100291681 - Khvorova; Anastasia ; et al. | 2010-11-18 |
| Modified polynucleotides for reducing off-target effects in RNA interference Grant 7,834,171 - Leake , et al. November 16, 2 | 2010-11-16 |
| Functional and hyperfunctional siRNA Grant 7,834,170 - Khvorova , et al. November 16, 2 | 2010-11-16 |
| siRNA targeting connective tissue growth factor (CTGF) Grant 7,833,989 - Khvorova , et al. November 16, 2 | 2010-11-16 |
| siRNA targeting amyloid beta (A4) precursor protein (APP) Grant 7,829,696 - Khvorova , et al. November 9, 2 | 2010-11-09 |
| siRNA Targeting Interleukin-1 Receptor-Associated Kinase 4(IRAK4) App 20100279896 - Khvorova; Anastasia ; et al. | 2010-11-04 |
| Screening Of Micro-rna Cluster Inhibitor Pools App 20100273856 - Smith; Anja ; et al. | 2010-10-28 |
| Functional and hyperfunctional siRNA directed against Bcl-2 Grant 7,820,809 - Khvorova , et al. October 26, 2 | 2010-10-26 |
| siRNA targeting cyclin dependent kinase 11 (CDK11) App 20100267587 - KHVOROVA; ANASTASIA ; et al. | 2010-10-21 |
| siRNA targeting KRAS App 20100267586 - Khvorova; Anastasia ; et al. | 2010-10-21 |
| siRNA targeting proto-oncogene MET Grant 7,816,512 - Khvorova , et al. October 19, 2 | 2010-10-19 |
| siRNA targeting survivin Grant 7,807,819 - Khvorova , et al. October 5, 2 | 2010-10-05 |
| siRNA targeting beta secretase (BACE) Grant 7,807,820 - Khvorova , et al. October 5, 2 | 2010-10-05 |
| siRNA targeting ribonucleotide reductase M2 polypeptide (RRM2 or RNR-R2) App 20100248990 - Khvorova; Anastasia ; et al. | 2010-09-30 |
| siRNA targeting TATA box binding protein (TBP)-associated factor (TAF1) Grant 7,803,933 - Khvorova , et al. September 28, 2 | 2010-09-28 |
| siRNA Targeting Glucagon Receptor (GCGR) App 20100240554 - Khvorova; Anastasia ; et al. | 2010-09-23 |
| siRNA targeting gremlin App 20100234582 - Khvorova; Anastasia ; et al. | 2010-09-16 |
| siRNA target hypoxia-inducible factor 1 App 20100234583 - Khvorova; Anastasia ; et al. | 2010-09-16 |
| Functional and hyperfunctional siRNA directed against Bcl-2 Grant 7,795,420 - Khvorova , et al. September 14, 2 | 2010-09-14 |
| siRNA targeting apolipoprotein B (APOB) Grant 7,795,421 - Khvorova , et al. September 14, 2 | 2010-09-14 |
| siRNA targeting tumor protein 53 (p53) Grant 7,781,575 - Khvorova , et al. August 24, 2 | 2010-08-24 |
| Modified Polynucleotides For Use In Rna Interference App 20100197023 - Leake; Devin ; et al. | 2010-08-05 |
| siRNA Targeting Diacylglycerol O-Acyltransferase Homolog 2 (DGAT2) App 20100190971 - Khvorova; Anastasia ; et al. | 2010-07-29 |
| Compositions And Methods For Inhibiting Gene Silencing By Rna Interference App 20100184209 - Vermeulen; Annaleen ; et al. | 2010-07-22 |
| siRNA targeting cyclin dependent kinase 11 (CDK11) Grant 7,745,610 - Khvorova , et al. June 29, 2 | 2010-06-29 |
| siRNA targeting interleukin-1 receptor-associated kinase 4 (IRAK4) Grant 7,745,612 - Khvorova , et al. June 29, 2 | 2010-06-29 |
| siRNA targeting KRAS Grant 7,745,611 - Khvorova , et al. June 29, 2 | 2010-06-29 |
| siRNA targeting gremlin Grant 7,741,470 - Khvorova , et al. June 22, 2 | 2010-06-22 |
| siRNA targeting BCL2L1 App 20100152064 - Khvorova; Anastasia ; et al. | 2010-06-17 |
| siRNA targeting hypoxia-inducible factor 1 Grant 7,737,267 - Khvorova , et al. June 15, 2 | 2010-06-15 |
| siRNA targeting nucleoporin 62kDa (Nup62) App 20100145039 - Khvorova; Anastasia ; et al. | 2010-06-10 |
| siRNA targeting serine/threonine kinase 12 (STK12 or aurora B kinase) App 20100144552 - Khvorova; Anastasia ; et al. | 2010-06-10 |
| siRNA targeting vascular endothelial growth factor (VEGF) App 20100113307 - Khvorova; Anastasia ; et al. | 2010-05-06 |
| siRNA targeting beta secretase (BACE) App 20100113761 - Khvorova; Anastasia ; et al. | 2010-05-06 |
| siRNA targeting myeloid differentiation primary response gene (88) (MYD88) App 20100113760 - Khvorova; Anastasia ; et al. | 2010-05-06 |
| siRNA Targeting connective tissue growth factor (CTGF) App 20100113306 - Khvorova; Anastasia ; et al. | 2010-05-06 |
| siRNA targeting diacylglycerol O-acyltransferase homolog 2 (DGAT2) Grant 7,709,629 - Khvorova , et al. May 4, 2 | 2010-05-04 |
| siRNA Targeting Fructose-1, 6-bisphosphatase 1 (FBP1) App 20100099578 - Khvorova; Anastasia ; et al. | 2010-04-22 |
| Tripartite Oligonucleotide Complexes And Methods For Gene Silencing By Rna Interference App 20100093085 - Yamada; Christina ; et al. | 2010-04-15 |
| siRNA targeting complement factor B Grant 7,696,344 - Khvorova , et al. April 13, 2 | 2010-04-13 |
| siRNA targeting superoxide dismutase 1 (SOD1) App 20100087334 - Khvorova; Anastasia ; et al. | 2010-04-08 |
| siRNA targeting spleen tyrosine kinase App 20100087335 - Khvorova; Anastasia ; et al. | 2010-04-08 |
| siRNA targeting nucleoporin 62kDa (Nup62) Grant 7,691,998 - Khvorova , et al. April 6, 2 | 2010-04-06 |
| Functional and hyperfunctional siRNA Grant 7,691,997 - Khvorova , et al. April 6, 2 | 2010-04-06 |
| siRNA targeting TATA box binding protein (TBP)-associated factor (TAF1) App 20100075869 - Khvorova; Anastasia ; et al. | 2010-03-25 |
| siRNA targeting amyloid beta (A4) precursor protein (APP) App 20100069622 - Khvorova; Anastasia ; et al. | 2010-03-18 |
| siRNA targeting proto-oncogene MET App 20100069261 - Khvorova; Anastasia ; et al. | 2010-03-18 |
| siRNA targeting serine/threonine kinase 12 (STK12 or aurora B kinase) Grant 7,678,896 - Khvorova , et al. March 16, 2 | 2010-03-16 |
| siRNA targeting TIE-2 App 20100062951 - Khvorova; Anastasia ; et al. | 2010-03-11 |
| siRNA targeting BCL2L1 Grant 7,674,896 - Khvorova , et al. March 9, 2 | 2010-03-09 |
| siRNA targeting coatomer protein complex, subunit beta 2 (CPOB2) App 20100056395 - Khvorova; Anastasia ; et al. | 2010-03-04 |
| siRNA targeting tumor protein 53 (P53) App 20100048425 - Khvorova; Anastasia ; et al. | 2010-02-25 |
| siRNA targeting connective tissue growth factor (CTGF) Grant 7,666,853 - Khvorova , et al. February 23, 2 | 2010-02-23 |
| siRNA targeting myeloid differentiation primary response gene (88) (MYD88) Grant 7,662,950 - Khvorova , et al. February 16, 2 | 2010-02-16 |
| siRNA targeting survivin App 20100029510 - Khvorova; Anastasia ; et al. | 2010-02-04 |
| siRNA targeting transient receptor potential cation channel, subfamily V, member 1 (TRPV1) Grant 7,655,789 - Khvorova , et al. February 2, 2 | 2010-02-02 |
| siRNA targeting DNA-damage-inducible transcript 4 (DDIT4) Grant 7,655,788 - Khvorova , et al. February 2, 2 | 2010-02-02 |
| siRNA targeting Ras-related nuclear protein RAN App 20100022413 - Khvorova; Anastasia ; et al. | 2010-01-28 |
| siRNA targeting kinase insert domain receptor (KDR) App 20100022763 - Khvorova; Anastasia ; et al. | 2010-01-28 |
| siRNA targeting cyclin-dependent kinase inhibitor 1B (p27, Kip1) (CDKN1B) App 20100016573 - Khvorova; Anastasia ; et al. | 2010-01-21 |
| siRNA targeting histamine receptor H1 App 20100016176 - Khvorova; Anastasia ; et al. | 2010-01-21 |
| siRNA Targeting Hypoxia-Inducible Factor 1 App 20100010206 - Khvorova; Anastasia ; et al. | 2010-01-14 |
| siRNA targeting proteasome 26S subunit, non-ATPase, 10 (Gankyrin or PSMD10) Grant 7,645,870 - Khvorova , et al. January 12, 2 | 2010-01-12 |
| siRNA targeting spleen tyrosine kinase Grant 7,645,869 - Khvorova , et al. January 12, 2 | 2010-01-12 |
| siRNA targeting polo-like Kinase-1 (PLK-1) App 20100004141 - Khvorova; Anastasia ; et al. | 2010-01-07 |
| siRNA targeting myeloid cell Leukemia sequence 1 App 20100004142 - Khvorova; Anastasia ; et al. | 2010-01-07 |
| siRNA targeting TATA box binding protein (TBP)-associated factor (TAF1) Grant 7,642,349 - Khvorova , et al. January 5, 2 | 2010-01-05 |
| siRNA targeting interleukin-1 receptor-associated kinase 4 (IRAK4) App 20090325818 - Khvorova; Anastasia ; et al. | 2009-12-31 |
| SiRNA targeting intercellular adhesion molecule 1 (ICAM1) Grant 7,638,622 - Khvorova , et al. December 29, 2 | 2009-12-29 |
| siRNA targeting insulin-like growth factor 1 receptor (IGF-1R) Grant 7,638,621 - Khvorova , et al. December 29, 2 | 2009-12-29 |
| siRNA targeting amyloid beta (A4) precursor protein (APP) Grant 7,635,771 - Khvorova , et al. December 22, 2 | 2009-12-22 |
| siRNA targeting protein kinase N-3 (PKN-3) Grant 7,635,770 - Khvorova , et al. December 22, 2 | 2009-12-22 |
| siRNA targeting proto-oncogene MET Grant 7,632,939 - Khvorova , et al. December 15, 2 | 2009-12-15 |
| siRNA targeting superoxide dismutase 1 (SOD1) Grant 7,632,938 - Khvorova , et al. December 15, 2 | 2009-12-15 |
| siRNA Targeting TNFalpha App 20090306356 - Khvorova; Anastasia ; et al. | 2009-12-10 |
| siRNA targeting KRAS App 20090298176 - Khvorova; Anastasia ; et al. | 2009-12-03 |
| siRNA targeting transducin (beta)-like 3 (TBL3) App 20090291497 - Khvorova; Anastasia ; et al. | 2009-11-26 |
| siRNA targeting coatomer protein complex, subunit beta 2 (COPB2) Grant 7,619,081 - Khvorova , et al. November 17, 2 | 2009-11-17 |
| Stabilized Sirnas As Transfection Controls And Silencing Reagents App 20090280567 - Leake; Devin ; et al. | 2009-11-12 |
| siRNA Targeting v-myc myelocytomatosis viral oncogene homolog (MYC) App 20090281297 - Khvorova; Anastasia ; et al. | 2009-11-12 |
| siRNA targeting TIE-2 Grant 7,615,541 - Khvorova , et al. November 10, 2 | 2009-11-10 |
| siRNA targeting inner centromere protein antigens (INCENP) App 20090275640 - Khvorova; Anastasia ; et al. | 2009-11-05 |
| siRNA targeting cyclin-dependent kinase inhibitor 1B (p27, Kip1) (CDKN1B) Grant 7,612,196 - Khvorova , et al. November 3, 2 | 2009-11-03 |
| siRNA targeting survivin Grant 7,608,707 - Khvorova , et al. October 27, 2 | 2009-10-27 |
| siRNA targeting ras-related nuclear protein Grant 7,608,706 - Khvorova , et al. October 27, 2 | 2009-10-27 |
| siRNA targeting kinase insert domain receptor (KDR) Grant 7,605,252 - Khvorova , et al. October 20, 2 | 2009-10-20 |
| siRNA targeting cAMP-specific phosphodiesterase 4D Grant 7,605,250 - Khvorova , et al. October 20, 2 | 2009-10-20 |
| siRNA targeting gremlin App 20090253776 - Khvorova; Anastasia ; et al. | 2009-10-08 |
| siRNA targeting histamine receptor H1 Grant 7,598,369 - Khvorova , et al. October 6, 2 | 2009-10-06 |
| siRNA targeting polo-like kinase-1 (PLK-1) Grant 7,598,370 - Khvorova , et al. October 6, 2 | 2009-10-06 |
| Modified polynucleotides for reducing off-target effects in RNA interference Grant 7,595,387 - Leake , et al. September 29, 2 | 2009-09-29 |
| siRNA targeting EPH receptor A3 (EPHA3) Grant 7,595,388 - Khvorova , et al. September 29, 2 | 2009-09-29 |
| siRNA targeting casitas B cell lymphoma-B (CBL-B) Grant 7,595,389 - Khvorova , et al. September 29, 2 | 2009-09-29 |
| siRNA targeting ribonucleotide reductase M2 polypeptide (RRM2 or RNR-R2) Grant 7,592,442 - Khvorova , et al. September 22, 2 | 2009-09-22 |
| siRNA targeting interleukin-1 receptor-associated kinase 4 (IRAK4) Grant 7,592,443 - Khvorova , et al. September 22, 2 | 2009-09-22 |
| siRNA targeting myeloid cell leukemia sequence 1 Grant 7,592,444 - Khvorova , et al. September 22, 2 | 2009-09-22 |
| siRNA targeting hypoxia-inducible factor 1 Grant 7,589,191 - Khvorova , et al. September 15, 2 | 2009-09-15 |
| siRNA targeting connexin 43 App 20090227780 - Khvorova; Anastasia ; et al. | 2009-09-10 |
| siRNA targeting complement component 3 (C3) Grant 7,582,746 - Khvorova , et al. September 1, 2 | 2009-09-01 |
| siRNA targeting inner centromere protein antigens (INCENP) Grant 7,582,747 - Khvorova , et al. September 1, 2 | 2009-09-01 |
| siRNA targeting carbonic anhydrase II Grant 7,579,457 - Khvorova , et al. August 25, 2 | 2009-08-25 |
| siRNA targeting synuclein, alpha (SNCA-1) Grant 7,579,458 - Khvorova , et al. August 25, 2 | 2009-08-25 |
| Duplex Oligonucleotides with Enhanced Functionality in Gene Regulation App 20090209626 - Khvorova; Anastasia ; et al. | 2009-08-20 |
| SiRNA targeting KRAS Grant 7,576,197 - Khvorova , et al. August 18, 2 | 2009-08-18 |
| siRNA targeting transducin (beta)-like 3 (TBL3) Grant 7,576,196 - Khvorova , et al. August 18, 2 | 2009-08-18 |
| siRNA targeting cyclin-dependent kinase 4 (CDK4) App 20090203895 - Khvorova; Anastasia ; et al. | 2009-08-13 |
| siRNA targeting gremlin Grant 7,569,684 - Khvorova , et al. August 4, 2 | 2009-08-04 |
| siRNA targeting connective tissue growth factor (CTGF) App 20090191625 - Khvorova; Anastasia ; et al. | 2009-07-30 |
| siRNA targeting phosphatases App 20090182134 - Khvorova; Anastasia ; et al. | 2009-07-16 |
| siRNA targeting Myeloid cell leukemia sequence 1 App 20090163702 - Khvorova; Anastasia ; et al. | 2009-06-25 |
| siRNA targeting tumor necrosis factor receptor superfamily member 1A App 20090163701 - Khvorova; Anastasia ; et al. | 2009-06-25 |
| siRNA targeting cell division cycle 20 homolog (CDC20) Grant 7,550,572 - Khvorova , et al. June 23, 2 | 2009-06-23 |
| siRNA Targeting Hypoxia-inducible Factor 1 App 20090156797 - Khvorova; Anastasia ; et al. | 2009-06-18 |
| siRNA Targeting KRAS App 20090149644 - Khvorova; Anastasia ; et al. | 2009-06-11 |
| siRNA targeting aquaporin 4 Grant 7,541,453 - Khvorova , et al. June 2, 2 | 2009-06-02 |
| siRNA targeting nucleoporin 62kDa (Nup62) App 20090118489 - Khvorova; Anastasia ; et al. | 2009-05-07 |
| siRNA targeting connexin 43 Grant 7,521,191 - Khvorova , et al. April 21, 2 | 2009-04-21 |
| siRNA targeting myeloid cell leukemia sequence 1 Grant 7,514,550 - Khvorova , et al. April 7, 2 | 2009-04-07 |
| siRNA targeting Transducin (beta)-like 3 (TBL3) App 20090088563 - Khvorova; Anastasia ; et al. | 2009-04-02 |
| Functional and hyperfunctional siRNA directed against Bcl-2 Grant 7,511,132 - Khvorova , et al. March 31, 2 | 2009-03-31 |
| siRNA targeting TATA box binding protein (TBP)-associated factor (TAF1) App 20090082556 - Khvorova; Anastasia ; et al. | 2009-03-26 |
| siRNA targeting KRAS Grant 7,507,811 - Khvorova , et al. March 24, 2 | 2009-03-24 |
| siRNA targeting inner centromere protein antigens (INCENP) App 20090069265 - Khvorova; Anastasia ; et al. | 2009-03-12 |
| siRNA targeting minichromosome maintenance deficient 3 (MCM3) App 20090043084 - Khvorova; Anastasia ; et al. | 2009-02-12 |
| siRNA targeting 1-acylglycerol-3-phosphate O-acyltransferase 2 (AGPAT2) App 20090030190 - Khvorova; Anastasia ; et al. | 2009-01-29 |
| siRNA targeting ribosomal protein S2 (RPS2) App 20090023908 - Khvorova; Anastasia ; et al. | 2009-01-22 |
| siRNA targeting kinesin spindle protein (KSP) App 20090023907 - Khvorova; Anastasia ; et al. | 2009-01-22 |
| siRNA targeting nuclear receptor interacting protein 1 (NRIP1) App 20090005548 - Khvorova; Anastasia ; et al. | 2009-01-01 |
| siRNa targeting neuropilin 1 (NRP1) App 20090005547 - Khvorova; Anastasia ; et al. | 2009-01-01 |
| siRNA targeting protein kinase N-3 (PKN-3) App 20080319180 - Khvorova; Anastasia ; et al. | 2008-12-25 |
| siRNA targeting proprotein convertase subtilisin/kexin type 9 (PCSK9) App 20080306015 - Khvorova; Anastasia ; et al. | 2008-12-11 |
| siRNA targeting vascular endothelial growth factor receptor 1 (VEGFR1) App 20080300395 - Khvorova; Anastasia ; et al. | 2008-12-04 |
| siRNA targeting casitas B cell lymphoma-B (CBL-B) App 20080293593 - Khvorova; Anastasia ; et al. | 2008-11-27 |
| siRNA targeting protein tyrosine phosphatase-1B (PTP1B) App 20080293595 - Khvorova; Anastasia ; et al. | 2008-11-27 |
| siRNA targeting forkhead box P3 (FOXP3) App 20080268457 - Khvorova; Anastasia ; et al. | 2008-10-30 |
| Modified Polynucleotides For Reducing Off-target Effects In Rna Interference App 20080242851 - Khvorova; Anastasia ; et al. | 2008-10-02 |
| siRNA targeting ribonucleotide reductase M2 polypeptide (RRM2 or RNR-R2) App 20080227967 - Khvorova; Anastasia ; et al. | 2008-09-18 |
| siRNA targeting cystic fibrosis transmembrane conductance regulator (CFTR) App 20080221317 - Khvorova; Anastasia ; et al. | 2008-09-11 |
| siRNA targeting ethanolamine Kinase I1 (EKI1) App 20080221316 - Khvorova; Anastasia ; et al. | 2008-09-11 |
| siRNA targeting 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (ATIC) App 20080207884 - Khvorova; Anastasia ; et al. | 2008-08-28 |
| siRNA targeting human hairless protein (HR) App 20080188648 - Khvorova; Anastasia ; et al. | 2008-08-07 |
| siRNA targeting DNA-damage-inducible transcript 4 (DDIT4) App 20080188647 - Khvorova; Anastasia ; et al. | 2008-08-07 |
| siRNA targeting cyclin-dependent kinase inhibitor 1B (p27, Kip1) (CDKN1B) App 20080177051 - Khvorova; Anastasia ; et al. | 2008-07-24 |
| siRNA targeting serine/threonine protein kinase AKT App 20080161547 - Khvorova; Anastasia ; et al. | 2008-07-03 |
| siRNA targeting myeloid cell leukemia sequence 1 App 20080139798 - Khvorova; Anastasia ; et al. | 2008-06-12 |
| siRNA Targeting synuclein, alpha (SNCA-1) App 20080139799 - Khvorova; Anastasia ; et al. | 2008-06-12 |
| siRNA targeting kinase insert domain receptor (KDR) App 20080132691 - Khvorova; Anastasia ; et al. | 2008-06-05 |
| siRNA targeting apolipoprotein B (APOB) App 20080113370 - Khvorova; Anastasia ; et al. | 2008-05-15 |
| siRNA Targeting proto-oncogene MET App 20080113377 - Khvorova; Anastasia ; et al. | 2008-05-15 |
| siRNA targeting glucagon receptor (GCGR) App 20080113372 - Khvorova; Anastasia ; et al. | 2008-05-15 |
| siRNA targeting superoxide dismutase 1 (SOD1) App 20080113375 - Khvorova; Anastasia ; et al. | 2008-05-15 |
| siRNA targeting diacylglycerol O-acyltransferase homolog 2 (DGAT2) App 20080113369 - Khvorova; Anastasia ; et al. | 2008-05-15 |
| siRNA targeting fructose-1,6-bisphosphatase 1 (FBP1) App 20080113374 - Khvorova; Anastasia ; et al. | 2008-05-15 |
| Functional and hyperfunctional siRNA directed against Bcl-2 App 20080114162 - Khvorova; Anastasia ; et al. | 2008-05-15 |
| siRNA targeting myeloid differentiation primary response gene (88) (MYD88) App 20080113376 - Khvorova; Anastasia ; et al. | 2008-05-15 |
| siRNA targeting beta secretase (BACE) App 20080113371 - Khvorova; Anastasia ; et al. | 2008-05-15 |
| siRNA targeting interleukin-1 receptor-associated kinase 4 (IRAK4) App 20080113378 - Khvorova; Anastasia ; et al. | 2008-05-15 |
| siRNA targeting amyloid beta (A4) precursor protein (APP) App 20080113373 - Khvorova; Anastasia ; et al. | 2008-05-15 |
| Functional and hyperfunctional siRNA directed against Bcl-2 App 20080108802 - Khvorova; Anastasia ; et al. | 2008-05-08 |
| Functional and hyperfunctional siRNA directed against Bcl-2 App 20080108803 - Khvorova; Anastasia ; et al. | 2008-05-08 |
| Functional and hyperfunctional siRNA directed against Bcl-2 App 20080097090 - Khvorova; Anastasia ; et al. | 2008-04-24 |
| siRNA targeting TNFalpha App 20080097091 - Khvorova; Anastasia ; et al. | 2008-04-24 |
| siRNA targeting kinases App 20080097092 - Khvorova; Anastasia ; et al. | 2008-04-24 |
| siRNA targeting deubiqutination enzymes App 20080097089 - Khvorova; Anastasia ; et al. | 2008-04-24 |
| Functional and hyperfunctional siRNA directed against Bcl-2 App 20080091004 - Khvorova; Anastasia ; et al. | 2008-04-17 |
| siRNA targeting complement component 3 (C3) App 20080090997 - Khvorova; Anastasia ; et al. | 2008-04-17 |
| Functional and hyperfunctional siRNA directed against Bcl-2 App 20080091001 - Khvorova; Anastasia ; et al. | 2008-04-17 |
| Functional and hyperfunctional siRNA directed against Bcl-2 App 20080091002 - Khvorova; Anastasia ; et al. | 2008-04-17 |
| Functional and hyperfunctional siRNA directed against Bcl-2 App 20080091003 - Khvorova; Anastasia ; et al. | 2008-04-17 |
| siRNA targeting transient receptor potential cation channel, subfamily V, member 1 (TRPV1) App 20080085998 - Khvorova; Anastasia ; et al. | 2008-04-10 |
| siRNA targeting phosphoinositide-3-kinase, class 2, beta polypeptide (PIK3C2B) App 20080085997 - Khvorova; Anastasia ; et al. | 2008-04-10 |
| siRNA targeting secreted frizzled-related protein 1 (sFRP1) App 20080086002 - Khvorova; Anastasia ; et al. | 2008-04-10 |
| siRNA targeting intercellular adhesion molecule 1 (ICAM1) App 20080086001 - Khvorova; Anastasia ; et al. | 2008-04-10 |
| Duplex Oligonucleotide Complexes And Methods For Gene Silencing By Rna Interference App 20080085869 - Yamada; Christina ; et al. | 2008-04-10 |
| siRNA targeting carbonic anhydrase 4(CA4) App 20080081904 - Khvorova; Anastasia ; et al. | 2008-04-03 |
| siRNA targeting nuclear receptors App 20080076908 - Khvorova; Anastasia ; et al. | 2008-03-27 |
| siRNA targeting ubiquitin ligases App 20080071073 - Khvorova; Anastasia ; et al. | 2008-03-20 |
| siRNA targeting proteasome 26S subunit, non-ATPase, 10 (Gankyrin or PSMD10) App 20080071075 - Khvorova; Anastasia ; et al. | 2008-03-20 |
| siRNA targeting cyclin dependent kinase 11 (CDK11) App 20080064865 - Khvorova; Anastasia ; et al. | 2008-03-13 |
| siRNA targeting platelet-derived growth factor receptor beta polypeptide (PDGFR) App 20080045703 - Khvorova; Anastasia ; et al. | 2008-02-21 |
| siRNA targeting neuropeptide Y (NPY) App 20080039617 - Khvorova; Anastasia ; et al. | 2008-02-14 |
| siRNA targeting vascular endothelial growth factor (VEGF) App 20080027215 - Khvorova; Anastasia ; et al. | 2008-01-31 |
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