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Process for synthesizing heterocyclic compounds
Grant 8,653,259 - Heinelt , et al. February 18, 2 | 2014-02-18 |
Substituted 4-phenyltetrahydroisoquinolines, process for their preparation, pharmaceutical compositions and therapeutic use
Grant 8,455,515 - Lang June 4, 2 | 2013-06-04 |
Substituted 1-amino-4-phenyl-dihydroisoquinolines, methods for the production thereof, use thereof as a medicament, and medicaments containing them
Grant 8,124,621 - Lang , et al. February 28, 2 | 2012-02-28 |
Substituted 2-amino-4-phenyldihydroquinolines, processes for their preparation, pharmaceutical compositions and methods for their use
Grant 8,106,204 - Lang , et al. January 31, 2 | 2012-01-31 |
N-substituted (benzoimidazol-2-yl)phenylamines, processes for their preparation, their use as a medicament or diagnostic aid, and a medicament comprising them
Grant 8,067,614 - Heinelt , et al. November 29, 2 | 2011-11-29 |
Substituted 4-phenyltetrahydroisoquinolines, pharmaceutical compositions comprising them and therapeutic methods for their use
Grant 7,868,003 - Heinelt , et al. January 11, 2 | 2011-01-11 |
Substituted 4-phenyltetrahydroisoquinolines, pharmaceutical compositions thereof, methods for their preparation and therapeutic use
Grant 7,790,742 - Lang , et al. September 7, 2 | 2010-09-07 |
Substituted thiophenes: compositions, processes of making, and uses in disease treatment and diagnosis
Grant 7,763,643 - Lang , et al. July 27, 2 | 2010-07-27 |
N-Substituted (Benzoimidazol-2-yl)phenylamines, Processes for Their Preparation, Their Use as a Medicament or Diagnostic Aid, and a Medicament Comprising Them
App 20100168196 - HEINELT; Uwe ; et al. | 2010-07-01 |
Furosemide modulators of HM74
Grant 7,556,931 - Minnich , et al. July 7, 2 | 2009-07-07 |
Use Of Inhibitors Of The Cellular Na+/h+ Exchanger (nhe) For Preparing A Medicament For Normalizing Serum Lipids
App 20090143473 - LANG; Hans Jochen ; et al. | 2009-06-04 |
Substituted Thiophenes: Compositions, Processes Of Making, And Uses In Disease Treatment And Diagnosis
App 20090137630 - LANG; Hans-Jochen ; et al. | 2009-05-28 |
Novel Substituted 2-Amino-4-Phenyldihydroquinolines, Processes for their Preparation, Pharmaceutical Compositions and Methods for Their Use
App 20090118329 - Lang; Hans-Jochen ; et al. | 2009-05-07 |
Substituted 1-amino-4-phenyl-dihydroisoquinolines, Methods For The Production Thereof, Use Thereof As A Medicament, And Medicaments Containing Them
App 20090118327 - Lang; Hans-Jochen ; et al. | 2009-05-07 |
Substituted thiophenes: compositions, processes of making, and uses in disease treatment and diagnosis
Grant 7,488,746 - Lang , et al. February 10, 2 | 2009-02-10 |
Novel Substituted 2-aminoimidazoles, Process For Their Preparation, Their Use As Medicament Or Diagnostic Aid
App 20080275098 - HEINELT; Uwe ; et al. | 2008-11-06 |
Substituted 2-aminoimidazoles, process for their preparation, their use as medicament or diagnostic aid
Grant 7,442,717 - Heinelt , et al. October 28, 2 | 2008-10-28 |
Methods For The Improvement Of Memory And Neurological Function Comprising The Administration Of Compositions That Act As Inhibitors Of The Sodium Proton (na+ /h+ ) Exchanger, Subtype 5 (nhe-5)
App 20080234317 - KLEEMANN; Heinz-Werner ; et al. | 2008-09-25 |
Substituted 4-phenyltetrahydroisoquinolines, Process For Their Preparation, Pharmaceutical Compositions And Therapeutic Use
App 20080194621 - Lang; Hans-Jochen | 2008-08-14 |
N-Substituted (Benzoimidazol-2-yl)phenylamines, Processes for Their Preparation, Their Use as a Medicament or Diagnostic Aid, and a Medicament Comprising Them
App 20080167359 - HEINELT; Uwe ; et al. | 2008-07-10 |
Process For Synthesizing Heterocyclic Compounds
App 20080146797 - HEINELT; Uwe ; et al. | 2008-06-19 |
Substituted Thiophenes: Compositions, Processes Of Making, And Uses In Disease Treatment And Diagnosis
App 20080070947 - LANG; Hans-Jochen ; et al. | 2008-03-20 |
Substituted 4-phenyltetrahydroisoquinolines, Pharmaceuitcal Compositions Comprising Them And Therapeutic Methods For Their Use
App 20080058328 - HEINELT; Uwe ; et al. | 2008-03-06 |
Substituted thiophenes: compositions, processes of making, and uses in disease treatment and diagnosis
Grant 7,317,033 - Lang , et al. January 8, 2 | 2008-01-08 |
2-phenyl-indoles As Prostaglandin D2 Receptor Antagonists
App 20070265278 - HARRIS; Keith J. ; et al. | 2007-11-15 |
Substituted 4-phenyltetrahyrdoisoquinolines, Pharmaceutical Compositions Thereof, Methods For Their Preparation And Therapeutic Use
App 20070225323 - LANG; Hans-Jochen ; et al. | 2007-09-27 |
Furosemide Modulators Of Hm74
App 20070213391 - MINNICH; Ann ; et al. | 2007-09-13 |
Composition, process of making, and medical use of substituted 4-phenyltetrahydroisoquinolines
Grant 7,241,775 - Hofmeister , et al. July 10, 2 | 2007-07-10 |
Furosemide modulators of HM74
Grant 7,232,811 - Minnich , et al. June 19, 2 | 2007-06-19 |
Substituted imidazolidines, process for their preparation, and their use as a medicament or diagnostic, and medicament comprising them
Grant 7,179,829 - Heinelt , et al. February 20, 2 | 2007-02-20 |
Substituted thienoimidazoles useful for disease treatment and prevention
Grant 7,179,830 - Lang , et al. February 20, 2 | 2007-02-20 |
Substituted thiophenes: compositions, processes of making, and uses in disease treatment and diagnosis
App 20060160873 - Lang; Hans-Jochen ; et al. | 2006-07-20 |
Substituted thiophenes: compositions, processes of making, and uses in disease treatment and diagnosis
Grant 7,049,333 - Lang , et al. May 23, 2 | 2006-05-23 |
Use of inhibitors of the sodium-dependent chloride/bicarbonate exchanger for the treatment of thrombotic and inflammatory disorders
App 20060025401 - Lang; Hans-Jochen ; et al. | 2006-02-02 |
Substituted benzimidazoles, processes for their preparation, their use as medicaments, and medicaments comprising them
Grant 6,958,357 - Hofmeister , et al. October 25, 2 | 2005-10-25 |
Furosemide modulators of HM74
App 20050187280 - Minnich, Anne ; et al. | 2005-08-25 |
Substituted 4-phenyltetrahydroisoquinolinium, process for their preparation, their use as a medicament, and medicament containing them
Grant 6,911,453 - Hofmeister , et al. June 28, 2 | 2005-06-28 |
Sulfonamide-substituted fused 7-membered ring compounds, their use as a medicament, and pharmaceutical preparations comprising them
Grant 6,908,947 - Brendel , et al. June 21, 2 | 2005-06-21 |
Substituted thienoimidazoles useful for disease treatment and prevention
App 20050075385 - Lang, Hans-Jochen ; et al. | 2005-04-07 |
N-substituted (benzoimidazol-2-yl) phenylamines, process for their preparation, their use as medicament or diagnostic aid, and medicament comprising them
App 20050054705 - Heinelt, Uwe ; et al. | 2005-03-10 |
Substituted 4-phenyltetrahydroisoquinolinium, process for their preparation, their use as a medicament, and medicament containing them
App 20050009864 - Hofmeister, Armin ; et al. | 2005-01-13 |
Composition, process of making, and medical use of substituted 4-phenyltetrahydroisoquinolines
App 20050009863 - Hofmeister, Armin ; et al. | 2005-01-13 |
Substituted imidazolidines, process for their preparation, and their use as a medicament or diagnostic, and medicament comprising them
App 20050004198 - Heinelt, Uwe ; et al. | 2005-01-06 |
Novel substituted 2-aminoimidazoles, process for their preparation, their use as medicament or diagnostic aid
App 20040259927 - Heinelt, Uwe ; et al. | 2004-12-23 |
Process for synthesizing heterocyclic compounds
App 20040242560 - Heinelt, Uwe ; et al. | 2004-12-02 |
Substituted norbornylamino derivatives, processes for their preparation, their use as medicaments or diagnostics, and a medicament comprising them
Grant 6,825,231 - Heinelt , et al. November 30, 2 | 2004-11-30 |
Use of inhibitors of the cellular Na+/H+ exchanger (NHE) for preparing a medicament for normalizing serum lipids
App 20040122096 - Lang, Hans Jochen ; et al. | 2004-06-24 |
Use of inhibitors of the sodium/hydrogen exchanger for the treatment of thrombotic and inflammatory disorders
App 20040097583 - Lang, Hans-Jochen ; et al. | 2004-05-20 |
Use of an inhibitor of the Na+/H+ exchanger for the production of a medicament for the treatment or prophylaxis of disturbances of the central nervous system
App 20040097544 - Lang, Hans Jochen ; et al. | 2004-05-20 |
Substituted heterocyclo-norbornylamino derivatives, processes for their preparation, their use as medicaments or diagnostics, and medicaments comprising them
Grant 6,737,423 - Heinelt , et al. May 18, 2 | 2004-05-18 |
Substituted 4-phenyltetrahydroisoquinolinium salts, process for their preparation, their use as a medicament, and medicament containing them
Grant 6,703,405 - Hofmeister , et al. March 9, 2 | 2004-03-09 |
Substituted benzoylguanidines, process for their preparation, their use as a medicament or diagnostic, and medicament containing them
Grant 6,703,411 - Weichert , et al. March 9, 2 | 2004-03-09 |
Diacyl-substituted guanidines, a process for their preparation, their use as medicament or diagnostic aid, and medicament containing them
App 20040044081 - Kleemann, Heinz-Werner ; et al. | 2004-03-04 |
Substituted 4-phenyltetrahydroisoquinolinium, process for their preparation, their use as a medicament, and medicament containing them
App 20040044211 - Hofmeister, Armin ; et al. | 2004-03-04 |
Substituted benzimidazoles, processes for their preparation, their use as medicaments, and medicaments comprising them
Grant 6,686,384 - Hofmeister , et al. February 3, 2 | 2004-02-03 |
Substituted thiophenes: compositions, processes of making, and uses in disease treatment and diagnosis
App 20040006119 - Lang, Hans-Jochen ; et al. | 2004-01-08 |
Use of inhibitors of the sodium-dependent chloride/bicarbonate exchanger for the treatment of thrombotic and inflammatory disorders
App 20030220383 - Lang, Hans-Jochen ; et al. | 2003-11-27 |
Monoacyl-substituted guanidines, a process for their preparation, their use as a medicament or diagnostic aid, and pharmaceutical compositions containing them
Grant 6,632,840 - Kleemann , et al. October 14, 2 | 2003-10-14 |
Substituted benzimidazoles, processes for their preparation, their use as medicaments, and medicaments comprising them
App 20030191170 - Hofmeister, Armin ; et al. | 2003-10-09 |
Substituted imidazolidines, process for their preparation, and their use as a medicament or diagnostic
App 20030187045 - Heinelt, Uwe ; et al. | 2003-10-02 |
Substituted 4-phenyltetrahydroisoquinolinium salts, process for their preparation, their use as a medicament, and medicament containing them
App 20030171580 - Hofmeister, Armin ; et al. | 2003-09-11 |
Heterocyclically substituted benzoylguanidines, process for their preparation, their use as medicaments or diagnostics, and medicaments comprising them
Grant 6,617,344 - Weichert , et al. September 9, 2 | 2003-09-09 |
Substituted 1-naphthoylguanidines, process for their preparation, their use as a medicament or diagnostic , and medicament containing them
Grant 6,600,072 - Brendel , et al. July 29, 2 | 2003-07-29 |
Heterocyclically Substituted Benzoylguanidines, Process For Their Preparation, Their Use As Medicaments Or Diagnostics, And Medicaments Comprising Them
App 20030139607 - Weichert, Andreas ; et al. | 2003-07-24 |
Substituted anthranilic acids, their use as a medicament or diagnostic, and medicament comprising them, and a pharmaceutical combination preparation containing a sodium/hydrogen exchange (NHE) blocker
Grant 6,593,352 - Weichert , et al. July 15, 2 | 2003-07-15 |
Substituted 1-naphthoylguanidines, process for their preparation, their use as a medicament or diagnostic, and medicament containing them
App 20030013760 - Brendel, Joachim ; et al. | 2003-01-16 |
Substituted heterocyclo-norbornylamino derivatives, processes for their preparation, their use as medicaments or diagnostics, and medicaments comprising them
App 20020173500 - Heinelt, Uwe ; et al. | 2002-11-21 |
Use of polycyclic 2-aminothiazole systems for the treatment of obesity
Grant 6,476,059 - Jahne , et al. November 5, 2 | 2002-11-05 |
Use of inhibitors of the sodium-hydrogen exchanger for the production of a medicament for decreasing undesired effects of substrates of the heart
Grant 6,462,024 - Lang , et al. October 8, 2 | 2002-10-08 |
Substituted benzimidazoles, processes for their preparation, their use as medicaments, and medicaments comprising them
App 20020132842 - Hofmeister, Armin ; et al. | 2002-09-19 |
Substituted anthranilic acids, their use as a medicament or diagnostic, and medicament comprising them, and a pharmaceutical combination preparation containing a sodium/hydrogen exchange (NHE) blocker
App 20020123632 - Weichert, Andreas ; et al. | 2002-09-05 |
Fluorophenyl-substituted alkenylcarboxylic acid guanidides, process for their preparation, their use as a medicament or diagnostic, and medicament containing them
App 20020123529 - Schwark, Jan-Robert ; et al. | 2002-09-05 |
8,8a-dihydroindeno[1,2-d]thiazole derivatives which carry in the 2-position a substituent having a sulfonamide structure or sulfone structure; processes for their preparation and their use as medicaments
App 20020103231 - Jaehne, Gerhard ; et al. | 2002-08-01 |
Heterocyclically substituted benzoylguanidines, process for their preparation, their use as medicaments or diagnostics, and medicaments comprising them
App 20020099222 - Weichert, Andreas ; et al. | 2002-07-25 |
Use of inhibitors of the sodium-hydrogen exchanger for preparing a medicament for preventing age-related disorders, and for prolonging life
Grant 6,420,430 - Linz , et al. July 16, 2 | 2002-07-16 |
Sulfonamide-substituted fused 7-membered ring compounds, their use as a medicament, and pharmaceutical preparations comprising them
App 20020072514 - Brendel, Joachim ; et al. | 2002-06-13 |
Substituted cinnamic, acid guanidides, process for their preparation, their use as a medicament, and medicament comprising them
Grant 6,399,824 - Hofmeister , et al. June 4, 2 | 2002-06-04 |
Substituted Cinnamic, Acid Guanidides, Process For Their Preparation, Their Use As A Medicament, And Medicament Comprising Them
App 20020058710 - Hofmeister, Armin, ; et al. | 2002-05-16 |
Use of inhibitors of the KQT1 channel and methods of controlling and treating diseases caused by helminths and ectoparasites
App 20020055537 - Gerlach, Uwe ; et al. | 2002-05-09 |
Five-membered heterocycles having biphenylsulfonyl substitution, process for their preparation, their use as a medicament or diagnostic, and medicament comprising them
App 20020045761 - Kleemann, Heinz-Werner ; et al. | 2002-04-18 |
Use of inhibitors of the KQTI channel and methods of controlling and treating diseases caused by helminths and ectoparasites
Grant 6,335,363 - Gerlach , et al. January 1, 2 | 2002-01-01 |
Heterocyclically substituted benzoylguanidines, process for their preparation, their use as medicaments or diagnostics, and medicaments comprising them
App 20010049446 - Weichert, Andreas ; et al. | 2001-12-06 |
8,8a-dihydroindeno[1,2-d]thiazole derivatives which carry in the 2-position a substituent having a sulfonamide structure or sulfone structure; processes for their preparation and their use as medicaments
App 20010039278 - Jaehne, Gerhard ; et al. | 2001-11-08 |
Substituted 8,8a-dihydro-3ah-indeno[1,2-d]thiazoles, processes for their preparation and their use as medicaments
App 20010031752 - Jaehne, Gerhard ; et al. | 2001-10-18 |
Substituted norbornylamino derivatives, processes for their preparation, their use as medicaments or diagnostics, and a medicament comprising them
App 20010023257 - Heinelt, Uwe ; et al. | 2001-09-20 |
Fluorophenyl-substituted alkenylcarboxylic acid guanidides, process for their preparation, their use as a medicament or diagnostic, and medicament containing them
App 20010020042 - Schwark, Jan-Robert ; et al. | 2001-09-06 |
Substituted benzoylguanidines, process for their preparation, their use as a medicament or diagnostic, and medicament containing them
App 20010016596 - Weichert, Andreas ; et al. | 2001-08-23 |
Polycyclic thiazol-2-ylidene amines, processes for their preparation and their use as medicaments
App 20010011096 - Jahne, Gerhard ; et al. | 2001-08-02 |
Polycyclic 2- aminothiazole systems, processes for their preparation and pharmaceuticals comprising these compounds
Grant 6,251,922 - Jahne , et al. June 26, 2 | 2001-06-26 |
Indanyl-substituted benzenecarboxamides, processes for their preparation, their use as a medicament, and pharmaceutical formulations containing them
Grant 6,221,866 - Brendel , et al. April 24, 2 | 2001-04-24 |
Polycyclic thiazole systems, processes for their preparation and pharmaceuticals comprising these compounds
Grant 6,187,801 - Jahne , et al. February 13, 2 | 2001-02-13 |
Substituted phenylalkenoylguanidines, process for their preparation, and their use in medicaments and in diagnostics
Grant 6,166,002 - Weichert , et al. December 26, 2 | 2000-12-26 |
Polycyclic thiazolidin-2-ylidene amines, process for their preparation, and their use as pharmaceuticals
Grant 6,159,996 - Jaehne , et al. December 12, 2 | 2000-12-12 |
Use of inhibitors of the sodium-hydrogen exchanger for the production of a pharmaceutical for the treatment of disorders which are caused by protozoa
Grant 6,114,393 - Lang , et al. September 5, 2 | 2000-09-05 |
Phenyl.-substituted alkenylcarboguanidides carrying perfluoroalkyl groups, a process for their preparation, their use as a medicament or diagnostic agent, and also a medicament containing them
Grant 6,025,349 - Schwark , et al. February 15, 2 | 2000-02-15 |
Sulfonamide-substituted benzopyran derivatives, processes for their preparation, their use as a medicament, and pharmaceutical preparations comprising them
Grant 6,008,245 - Brendel , et al. December 28, 1 | 1999-12-28 |
Substituted benzoylguanidines, process for their preparation, their use as a pharmaceutical as inhibitors of the cellular NA+/H+ exchange or as a diagnostic, and pharmaceutical containing them
Grant 5,866,610 - Lang , et al. February 2, 1 | 1999-02-02 |
Benzo-fused heterocyclic compounds having a 5-membered ring processes for their preparation their use as medicaments their use as diagnostic agents and medicaments containing them
Grant 5,852,046 - Lang , et al. December 22, 1 | 1998-12-22 |
Substituted benzyloxycarbonylguanidines, a process for their preparation, their use as a medicament or diagnostic, and a medicament containing them
Grant 5,753,710 - Kleemann , et al. May 19, 1 | 1998-05-19 |
Substituted sulfonimidamides, processes for their preparation, their use as a medicament or diagnostic, and medicament comprising them
Grant 5,708,034 - Kleemann , et al. January 13, 1 | 1998-01-13 |
Substituted N-heteroaroylguanidines, a process for their preparation, their use as a medicament or diagnostic agent, and a medicament containing them
Grant 5,698,581 - Kleemann , et al. December 16, 1 | 1997-12-16 |
Guanidinealkyl-1,1-bisphosphonic acid derivatives, process for their preparation and their use
Grant 5,661,174 - Naumann , et al. August 26, 1 | 1997-08-26 |
Benzoylguanidines, pharmaceutical composition containing them and treatment of arrthythmias therewith
Grant 5,591,754 - Lang , et al. January 7, 1 | 1997-01-07 |
Guanidinealkyl-1,1-bisphosphonic acid derivatives process for their preparation and their use
Grant 5,498,617 - Naumann , et al. March 12, 1 | 1996-03-12 |
Antiarrhythmic and cardioprotective substituted -1(2H)isoquinolines, medicament containing them, and their use for combating heart failures
Grant 5,416,094 - Lal , et al. May 16, 1 | 1995-05-16 |
Guanidinealkyl-1,1-bisphosphonic acid derivatives, process for their preparation and their use
Grant 5,395,826 - Naumann , et al. March 7, 1 | 1995-03-07 |
3,5-Substituted benzoylguanidines, process for their preparation, their use as a medicament of diagnostic and medicament containing them
Grant 5,373,024 - Lang , et al. December 13, 1 | 1994-12-13 |
Amino-substituted benzoylguanidines, process for their preparation, their use as a medicament and medicament containing them
Grant 5,364,868 - Englert , et al. November 15, 1 | 1994-11-15 |
Guanidinoalkyl-1,1-bisphosphonic acid derivatives, process for their preparation and their use
Grant 5,294,608 - Lang , et al. March 15, 1 | 1994-03-15 |
Benzenesulfonamides and a process for their preparation
Grant 5,143,937 - Lang , et al. September 1, 1 | 1992-09-01 |
Benzoylguanidines, a process for their preparation, their use as medicaments and medicaments containing them
Grant 5,091,394 - Englert , et al. February 25, 1 | 1992-02-25 |
N-substituted 5-nitroanthranilic acids, a process for their preparation, their use, and pharmaceutical products based on these compounds
Grant 4,994,493 - Greger , et al. February 19, 1 | 1991-02-19 |
Substituted thienoimidazole derivatives, a process for the preparation thereof, pharmaceutical compositions containing them, and the use thereof as inhibitors of gastric acid secretion, as gastroprotectives and as medicaments for intestinal inflammations
Grant 4,956,366 - Nimmesgern , et al. September 11, 1 | 1990-09-11 |
6-sulfoxyphenol derivatives, their preparation and their use as cytoprotective agents
Grant 4,661,636 - Englert , et al. April 28, 1 | 1987-04-28 |
Benzylamine derivatives and process for preparing them
Grant 4,024,274 - Druckrey , et al. May 17, 1 | 1977-05-17 |
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