| Patent | Date |
|---|
Libraries of genetic packages comprising novel HC CDR3 designs
Grant 9,873,957 - Ladner January 23, 2 | 2018-01-23 |
Prevention and reduction of blood loss
Grant 9,480,733 - Ladner , et al. November 1, 2 | 2016-11-01 |
Libraries of genetic packages comprising novel HC CDR1, CDR2, and CDR3 and novel LC CDR1, CDR2, and CDR3 designs
Grant 9,388,510 - Ladner July 12, 2 | 2016-07-12 |
Methods of constructing libraries of genetic packages that collectively display the members of a diverse family of peptides, polypeptides or proteins
Grant 9,382,535 - Ladner , et al. July 5, 2 | 2016-07-05 |
Kallikrein-inhibitor therapies
Grant 9,114,144 - Ladner , et al. August 25, 2 | 2015-08-25 |
Method for treating breast cancer using antibody binding to MMP-14
Grant 9,051,377 - Devy , et al. June 9, 2 | 2015-06-09 |
Methods of constructing libraries comprising displayed and/or expressed members of a diverse family of peptides, polypeptides or proteins and the novel libraries
Grant 8,901,045 - Ladner , et al. December 2, 2 | 2014-12-02 |
Prevention And Reduction Of Blood Loss
App 20140349940 - Ladner; Robert C. ; et al. | 2014-11-27 |
Ligand screening and discovery
Grant 8,846,579 - Hoogenboom , et al. September 30, 2 | 2014-09-30 |
Protease inhibition
Grant 8,828,703 - Ladner September 9, 2 | 2014-09-09 |
Kallikrein inhibitors and anti-thrombolytic agents and uses thereof
Grant 8,716,225 - Blair , et al. May 6, 2 | 2014-05-06 |
Prevention and reduction of blood loss
Grant 8,710,007 - Ladner , et al. April 29, 2 | 2014-04-29 |
Kallikrein-binding "kunitz domain" proteins and analogues thereof
Grant 8,663,629 - Markland , et al. March 4, 2 | 2014-03-04 |
KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy
Grant 8,642,010 - Sato , et al. February 4, 2 | 2014-02-04 |
Ligand Screening And Discovery
App 20130274112 - Hoogenboom; Henricus R J. ; et al. | 2013-10-17 |
Display library process
Grant 8,557,743 - Ladner , et al. October 15, 2 | 2013-10-15 |
Libraries and methods for isolating antibodies
Grant 8,551,920 - Hoet , et al. October 8, 2 | 2013-10-08 |
Ligand screening and discovery
Grant 8,445,410 - Hoogenboom , et al. May 21, 2 | 2013-05-21 |
Nucleic acids encoding polypeptide inhibitors of human plasmin derived from the Kunitz domains
Grant 8,431,359 - Markland , et al. April 30, 2 | 2013-04-30 |
Novel Methods Of Constructing Libraries Comprising Displayed And/or Expressed Members Of A Diverse Family Of Peptides, Polypeptides Or Proteins And The Novel Libraries
App 20130040861 - Ladner; Robert C. ; et al. | 2013-02-14 |
Kallikrein-binding "kunitz Domain" Proteins And Analogues Thereof
App 20120328517 - Markland; William ; et al. | 2012-12-27 |
Poly-pegylated Protease Inhibitors
App 20120322744 - Ley; Arthur C. ; et al. | 2012-12-20 |
Methods of constructing libraries comprising displayed and/or expressed members of a diverse family of peptides, polypeptides or proteins and the novel libraries
Grant 8,288,322 - Ladner , et al. October 16, 2 | 2012-10-16 |
Kallikrein-binding "Kunitz domain" proteins and analogues thereof
Grant 8,283,321 - Markland , et al. October 9, 2 | 2012-10-09 |
Kallikrein inhibitors and anti-thrombolytic agents and uses thereof
Grant 8,188,045 - Blair , et al. May 29, 2 | 2012-05-29 |
Metalloproteinase Binding Proteins
App 20120107231 - Devy; Laetitia ; et al. | 2012-05-03 |
Prevention and reduction of blood loss
Grant 8,124,586 - Ladner , et al. February 28, 2 | 2012-02-28 |
Hk1-binding Proteins
App 20120027686 - Sexton; Daniel J. ; et al. | 2012-02-02 |
Metalloproteinase binding proteins
Grant 8,106,168 - Devy , et al. January 31, 2 | 2012-01-31 |
Kallikrein-inhibitor Therapies
App 20120015881 - Ladner; Robert C. ; et al. | 2012-01-19 |
Kallikrein-inhibitor therapies
Grant 8,034,775 - Ladner , et al. October 11, 2 | 2011-10-11 |
HK1-binding proteins
Grant 7,993,646 - Sexton , et al. August 9, 2 | 2011-08-09 |
Libraries Of Genetic Packages Comprising Novel Hc Cdr1, Cdr2, And Cdr3 And Novel Lc Cdr1, Cdr2, And Cdr3 Designs
App 20110172125 - Ladner; Robert C. | 2011-07-14 |
Poly-Pegylated Protease Inhibitors
App 20110172140 - Ley; Arthur C. ; et al. | 2011-07-14 |
Inhibitors Of Human Plasmin Derived From The Kunitz Domains
App 20110152193 - Markland; William ; et al. | 2011-06-23 |
Kallikrein-Binding "Kunitz Domain" Proteins and Analogues Thereof
App 20110136746 - Markland; William ; et al. | 2011-06-09 |
Libraries Of Genetic Packages Comprising Novel Hc Cdr3 Designs
App 20110118147 - Ladner; Robert C. | 2011-05-19 |
Prevention And Reduction Of Blood Loss
App 20110086801 - Ladner; Robert C. ; et al. | 2011-04-14 |
Libraries Of Genetic Packages Comprising Novel Hc Cdr3 Designs
App 20110082054 - Ladner; Robert C. | 2011-04-07 |
Inhibitors of human plasmin derived from the Kunitz domains
Grant 7,919,462 - Markland , et al. April 5, 2 | 2011-04-05 |
Prevention and reduction of blood loss
Grant 7,851,442 - Ladner , et al. December 14, 2 | 2010-12-14 |
Metalloproteinase-binding Proteins
App 20100291001 - DRANSFIELD; DANIEL T. ; et al. | 2010-11-18 |
Plasmin-inhibitory Therapies
App 20100286061 - DEVY; Laetitia ; et al. | 2010-11-11 |
Metalloproteinase Binding Proteins
App 20100266490 - Devy; Laetitia ; et al. | 2010-10-21 |
Prevention and reduction of blood loss
Grant 7,811,991 - Ladner , et al. October 12, 2 | 2010-10-12 |
Antibodies that bind MMP-14
Grant 7,745,587 - Devy , et al. June 29, 2 | 2010-06-29 |
Kallikrein-inhibitor therapies
Grant 7,704,949 - Ladner , et al. April 27, 2 | 2010-04-27 |
Kallikrein-inhibitor Therapies
App 20100034805 - Ladner; Robert C. ; et al. | 2010-02-11 |
Kdr And Vegf/kdr Binding Peptides And Their Use In Diagnosis And Therapy
App 20100003195 - Sato; Aaron K. ; et al. | 2010-01-07 |
Kallikrein-binding "Kunitz domain" proteins and analogues thereof
Grant 7,628,983 - Markland , et al. December 8, 2 | 2009-12-08 |
Kallikrein inhibitors and anti-thrombolytic agents and uses thereof
App 20090264350 - Blair; Henry ; et al. | 2009-10-22 |
Kallikrein Inhibitors and Anti-thrombolytic Agents and Uses Thereof
App 20090247453 - Blair; Henry ; et al. | 2009-10-01 |
Kallikrein Inhibitors and Anti-Thrombolytic Agents and Uses Thereof
App 20090234009 - Blair; Henry ; et al. | 2009-09-17 |
Kallikrein Inhibitors and Anti-Thrombolytic Agents and Uses Thereof
App 20090233852 - Blair; Henry ; et al. | 2009-09-17 |
Kallikrein Inhibitors and Anti-Thrombolytic Agents and Uses Thereof
App 20090227494 - Blair; Henry ; et al. | 2009-09-10 |
Kallikrein Inhibitors and Anti-Thrombolytic Agents and Uses Thereof
App 20090227495 - Blair; Henry ; et al. | 2009-09-10 |
Kallikrein Inhibitors and Anti-Thrombolytic Agents and Uses Thereof
App 20090221480 - Blair; Henry ; et al. | 2009-09-03 |
Methods For Producing Specific Binding Pairs
App 20090215119 - Ladner; Robert C. | 2009-08-27 |
Novel methods of constructing libraries comprising displayed and/or expressed members of a diverse family of peptides, polypeptides or proteins and the novel libraries
App 20090162835 - Ladner; Robert C. ; et al. | 2009-06-25 |
Poly-pegylated protease inhibitors
Grant 7,550,427 - Ley , et al. June 23, 2 | 2009-06-23 |
Kallikrein-inhibitor Therapies
App 20090117130 - Ladner; Robert C. ; et al. | 2009-05-07 |
Ligand Screening and Discovery
App 20090105083 - Hoogenboom; Henricus Renerus ; et al. | 2009-04-23 |
Metalloproteinase-binding proteins
Grant 7,514,534 - Dransfield , et al. April 7, 2 | 2009-04-07 |
Prevention and Reduction of Blood Loss
App 20090082267 - Ladner; Robert C. ; et al. | 2009-03-26 |
Kallikrein-Inhibitor Therapies
App 20090062195 - Ladner; Robert C. ; et al. | 2009-03-05 |
Inhibitors Of Human Plasmin Derived From The Kunitz Domains
App 20090036365 - Markland; William ; et al. | 2009-02-05 |
Inhibitors Of Human Plasmin Derived From The Kunitz Domains
App 20090036366 - Markland; William ; et al. | 2009-02-05 |
Inhibitors Of Human Plasmin Derived From The Kunitz Domains
App 20090023651 - Markland; William ; et al. | 2009-01-22 |
Prevention And Reduction Of Blood Loss
App 20080260752 - Ladner; Robert C. ; et al. | 2008-10-23 |
Protease inhibition
App 20080255025 - Ladner; Robert C. | 2008-10-16 |
Methods of Making Passive Immunotherapies
App 20080241127 - Blair; Henry ; et al. | 2008-10-02 |
Kallikrein-Inhibitor Therapies
App 20080226655 - Ladner; Robert C. ; et al. | 2008-09-18 |
Kallikrein Inhibitors and Anti-Thrombolytic Agents and Uses Thereof
App 20080221031 - Blair; Henry ; et al. | 2008-09-11 |
Hk1-binding Proteins
App 20080213251 - Sexton; Daniel J. ; et al. | 2008-09-04 |
Prevention And Reduction Of Blood Loss
App 20080200646 - Ladner; Robert C. ; et al. | 2008-08-21 |
Kallikrein Inhibitors and Anti-Thrombolytic Agents and Uses Thereof
App 20080188409 - Blair; Henry ; et al. | 2008-08-07 |
Inhibitors Of Human Plasmin Derived From The Kunitz Domains
App 20080182283 - Markland; William ; et al. | 2008-07-31 |
Prevention And Reduction Of Blood Loss
App 20080152656 - Ladner; Robert C. ; et al. | 2008-06-26 |
Kallikrein-Inhibitor Therapies
App 20080139473 - Ladner; Robert C. ; et al. | 2008-06-12 |
Prevention and Reduction of Blood Loss
App 20080131426 - Ladner; Robert C. ; et al. | 2008-06-05 |
Prevention And Reduction Of Blood Loss
App 20080076712 - Ladner; Robert C. ; et al. | 2008-03-27 |
Prevention and reduction of blood loss
App 20080064637 - Ladner; Robert C. ; et al. | 2008-03-13 |
Antibodies that bind hK-1
Grant 7,329,737 - Sexton , et al. February 12, 2 | 2008-02-12 |
Kunitz Domain Library
App 20080020394 - Nixon; Andrew ; et al. | 2008-01-24 |
Prevention And Reduction Of Blood Loss
App 20070249807 - Ladner; Robert C. ; et al. | 2007-10-25 |
Prevention and reduction of blood loss
Grant 7,276,480 - Ladner , et al. October 2, 2 | 2007-10-02 |
Metalloproteinase binding proteins
App 20070217997 - Devy; Laetitia ; et al. | 2007-09-20 |
Ligand screening and discovery
Grant 7,244,592 - Hoogenboom , et al. July 17, 2 | 2007-07-17 |
Kallikrein inhibitors and anti-thrombolytic agents and uses thereof
Grant 7,235,530 - Blair , et al. June 26, 2 | 2007-06-26 |
Kallikrein-inhibitor Therapies
App 20070049522 - Ladner; Robert C. ; et al. | 2007-03-01 |
Poly-pegylated Protease Inhibitors
App 20070041959 - Ley; Arthur C. ; et al. | 2007-02-22 |
Novel enterokinase cleavage sequences
App 20070031879 - Ley; Arthur C. ; et al. | 2007-02-08 |
Modified protease inhibitors
App 20070020252 - Ladner; Robert C. ; et al. | 2007-01-25 |
HK1-binding proteins
App 20070004910 - Sexton; Daniel J. ; et al. | 2007-01-04 |
Kallikrein-inhibitor therapies
Grant 7,153,829 - Ladner , et al. December 26, 2 | 2006-12-26 |
Kallikrein-binding "Kunitz domain" proteins and analogues thereof
App 20060264603 - Markland; William ; et al. | 2006-11-23 |
Libraries and methods for isolating antibodies
App 20060234302 - Hoet; Rene ; et al. | 2006-10-19 |
Prevention and reduction of blood loss
App 20060194727 - Ladner; Robert C. ; et al. | 2006-08-31 |
Novel methods of constructing libraries of genetic packages that collectively display the members of a diverse family of peptides, polypeptides or proteins
App 20060166252 - Ladner; Robert C. ; et al. | 2006-07-27 |
ITI-D1 Kunitz domain mutants as HNE inhibitors
Grant 7,078,383 - Ley , et al. July 18, 2 | 2006-07-18 |
Prevention and reduction of blood loss
Grant 7,064,107 - Ladner , et al. June 20, 2 | 2006-06-20 |
Plasmin-inhibitory therapies
App 20060111296 - Devy; Laetitia ; et al. | 2006-05-25 |
Kallikrein inhibitors and anti-thrombolytic agents and uses thereof
App 20060069020 - Blair; Henry ; et al. | 2006-03-30 |
Metalloproteinase-binding proteins
App 20060036076 - Dransfield; Daniel T. ; et al. | 2006-02-16 |
KDR and VEGF/KDR binding peptides
App 20050250700 - Sato, Aaron K. ; et al. | 2005-11-10 |
Peptides that specifically bind HGF receptor (cMet) and uses thereof
App 20050214859 - Dransfield, Daniel T. ; et al. | 2005-09-29 |
Inhibitors of human plasmin derived from the kunitz domains
App 20050186649 - Markland, William ; et al. | 2005-08-25 |
Kallikrein-inhibitor therapies
App 20050164928 - Ladner, Robert C. ; et al. | 2005-07-28 |
Novel enterokinase cleavage sequences
App 20050158838 - Ley, Arthur C. ; et al. | 2005-07-21 |
KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy
App 20050100963 - Sato, Aaron K. ; et al. | 2005-05-12 |
Poly-pegylated protease inhibitors
App 20050089515 - Ley, Arthur C. ; et al. | 2005-04-28 |
Kunitz domain library
App 20040209243 - Nixon, Andrew ; et al. | 2004-10-21 |
Display library process
App 20040180327 - Ladner, Robert C. ; et al. | 2004-09-16 |
Prevention and reduction of blood loss
App 20040038893 - Ladner, Robert C. ; et al. | 2004-02-26 |
Novel methods of constructing libraries of genetic packages that collectively display the members of a diverse family of peptides, polypeptides or proteins
App 20040029113 - Ladner, Robert C. ; et al. | 2004-02-12 |
Novel methods of constructing librabries comprising displayed and/or expressed members of a diverse family of peptides, polypeptides or proteins and the novel librabries
App 20030232333 - Ladner, Robert C. ; et al. | 2003-12-18 |
Ligand screening and discovery
App 20030224408 - Hoogenboom, Henricus Renerus Jacobus Mattheus ; et al. | 2003-12-04 |
Modular recombinatorial display libraries
App 20030186223 - Ladner, Robert C. | 2003-10-02 |
Method and apparatus for washing magnetically responsive particles
App 20030170686 - Hoet, Rene ; et al. | 2003-09-11 |
Library screening
App 20030129659 - Whelihan, E. Fayelle ; et al. | 2003-07-10 |
Directed evolution of novel binding proteins
Grant 5,571,698 - Ladner , et al. * November 5, 1 | 1996-11-05 |
Immunoaffinity purification methods using single polypeptide chain binding molecules
Grant 5,534,621 - Ladner , et al. July 9, 1 | 1996-07-09 |
Immunotheraphy using single chain polypeptide binding molecules
Grant 5,455,030 - Ladner , et al. October 3, 1 | 1995-10-03 |
Viruses expressing chimeric binding proteins
Grant 5,403,484 - Ladner , et al. April 4, 1 | 1995-04-04 |
Single polypeptide chain binding molecules
Grant 5,260,203 - Ladner , et al. No | 1993-11-09 |
Directed evolution of novel binding proteins
Grant 5,223,409 - Ladner , et al. | 1993-06-29 |
Generation and selection of novel DNA-binding proteins and polypeptides
Grant 5,198,346 - Ladner , et al. March 30, 1 | 1993-03-30 |
Generation and selection of novel DNA-binding proteins and polypeptides
Grant 5,096,815 - Ladner , et al. March 17, 1 | 1992-03-17 |
Single polypeptide chain binding molecules
Grant 4,946,778 - Ladner , et al. | 1990-08-07 |
Computer designed stabilized proteins and method for producing same
Grant 4,908,773 - Pantoliano , et al. March 13, 1 | 1990-03-13 |
Computer based system and method for determining and displaying possible chemical structures for converting double- or multiple-chain polypeptides to single-chain polypeptides
Grant 4,881,175 - Ladner * November 14, 1 | 1989-11-14 |
Computer-based method for designing stablized proteins
Grant 4,853,871 - Pantoliano , et al. August 1, 1 | 1989-08-01 |
Computer based system and method for determining and displaying possible chemical structures for converting double- or multiple-chain polypeptides to single-chain polypeptides
Grant 4,704,692 - Ladner November 3, 1 | 1987-11-03 |
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