Patent applications and USPTO patent grants for Kosan Biosciences Incorporated.The latest application filed is for "esters of compounds in the leptomycin family".
Patent | Date |
---|---|
Intermediates and methods for the preparation of epothilones Grant 8,410,305 - Chen , et al. April 2, 2 | 2013-04-02 |
Ketolide anti-infective compounds Grant 8,063,021 - Li , et al. November 22, 2 | 2011-11-22 |
Process for the preparation of epothilones Grant 8,030,503 - Chen , et al. October 4, 2 | 2011-10-04 |
Esters of compounds in the leptomycin family Grant 8,003,687 - Dong , et al. August 23, 2 | 2011-08-23 |
Methods of making epothilones Grant 7,955,824 - Carney , et al. June 7, 2 | 2011-06-07 |
Macrolactams by engineered biosynthesis Grant 7,855,192 - Ashley , et al. December 21, 2 | 2010-12-21 |
Biosynthetic gene cluster for leptomycins Grant 7,851,190 - Hu , et al. December 14, 2 | 2010-12-14 |
Carbamate compounds Grant 7,795,457 - Fu , et al. September 14, 2 | 2010-09-14 |
Esters of Compounds in the Leptomycin Family App 20100222382 - Dong; Steven D ;   et al. | 2010-09-02 |
Recombinant methods and materials for producing epothilone and epothilone derivatives Grant 7,732,186 - Julien , et al. June 8, 2 | 2010-06-08 |
Polynucleotides encoding the fkbB gene of the FK-520 polyketide synthase gene cluster Grant 7,714,118 - Reeves , et al. May 11, 2 | 2010-05-11 |
Method of treating multiple myeloma using 17-AAG or 17-AG or a prodrug of either Grant 7,691,392 - Johnson, Jr. , et al. April 6, 2 | 2010-04-06 |
Method for treating diseases using HSP90-inhibiting agents in combination with antimitotics Grant 7,691,838 - Johnson, Jr. , et al. April 6, 2 | 2010-04-06 |
Recombinant polynucleotides encoding pro-geldanamycin producing polyketide synthases and accessory proteins, and uses thereof Grant 7,671,190 - Hutchinson , et al. March 2, 2 | 2010-03-02 |
Specific Kinase Inhibitors App 20100004234 - Santi; Daniel V. ;   et al. | 2010-01-07 |
Macrocyclic kinase inhibitors Grant 7,601,852 - Fu , et al. October 13, 2 | 2009-10-13 |
7-quinolyl ketolide antibacterial agents Grant 7,595,300 - Shaw , et al. September 29, 2 | 2009-09-29 |
Trans-9,10-dehydroepothilone C And D, Analogs Thereof And Methods Of Making The Same App 20090186927 - Li; Yong ;   et al. | 2009-07-23 |
Recombinant Methods and Materials for Producing Epothilone and Epothilone Derivatives App 20090170172 - Julien; Bryan ;   et al. | 2009-07-02 |
Conjugates with reduced adverse systemic effects Grant 7,541,330 - Santi , et al. June 2, 2 | 2009-06-02 |
Production of Polyketides App 20090111151 - Julien; Bryan ;   et al. | 2009-04-30 |
Benzoquinone Ansamycins App 20090111869 - SANTI; Daniel ;   et al. | 2009-04-30 |
Methods of Making Epothilones App 20090076289 - Carney; John R. ;   et al. | 2009-03-19 |
17-allylamino-17-demethoxygeldanamycin Polymorphs And Formulations App 20090042847 - Licari; Peter J. ;   et al. | 2009-02-12 |
Process For The Preparation Of Epothilones App 20080319211 - Chen; Yue ;   et al. | 2008-12-25 |
Method of producing a compound by fermentation Grant 7,459,294 - Leaf , et al. December 2, 2 | 2008-12-02 |
Synthetic genes App 20080274510 - Santi; Daniel V. ;   et al. | 2008-11-06 |
Leptomycin compounds Grant 7,446,196 - Dong , et al. November 4, 2 | 2008-11-04 |
Synthetic genes App 20080261300 - Santi; Daniel V. ;   et al. | 2008-10-23 |
Recombinant genes for polyketide modifying enzymes Grant 7,427,493 - Hutchinson , et al. September 23, 2 | 2008-09-23 |
Recombinant host cells expressing atoAD and capable of making a polyketide using a starter unit Grant 7,413,878 - Kealey , et al. August 19, 2 | 2008-08-19 |
Benzoquinone ansamycins Grant 7,405,208 - Santi , et al. July 29, 2 | 2008-07-29 |
Recombinant methods and materials for producing epothilone and epothilone derivatives Grant 7,402,421 - Julien , et al. July 22, 2 | 2008-07-22 |
Motilide polymorphs App 20080146654 - Licari; Peter J. ;   et al. | 2008-06-19 |
Geldanamycin compounds and method of use Grant 7,378,407 - Santi , et al. May 27, 2 | 2008-05-27 |
Fermentation and purification of migrastatin and analog Grant 7,375,230 - Khosla , et al. May 20, 2 | 2008-05-20 |
Polynucleotides encoding disorazole polyketide synthase polypeptides Grant 7,364,877 - Julien , et al. April 29, 2 | 2008-04-29 |
Compounds useful for the synthesis of (+)-discodermolide and methods thereof Grant 7,348,436 - Myles , et al. March 25, 2 | 2008-03-25 |
Synthetic techniques and intermediates for polyhydroxy dienyl lactones and mimics thereof Grant 7,342,124 - Myles , et al. March 11, 2 | 2008-03-11 |
Biosynthetic gene cluster for ambruticins and the encoded proteins Grant 7,332,576 - Reeves , et al. February 19, 2 | 2008-02-19 |
Production of polyketides Grant 7,323,573 - Arslanian January 29, 2 | 2008-01-29 |
Geldanamycin compounds and method of use App 20070270396 - Santi; Daniel V. ;   et al. | 2007-11-22 |
Genetically modified cells and methods for converting (R)-methylmalonyl CoA to (S)-methylmalonyl CoA Grant 7,291,486 - Santi , et al. November 6, 2 | 2007-11-06 |
Biosynthetic gene cluster for leptomycins Grant 7,288,396 - Hu , et al. October 30, 2 | 2007-10-30 |
Biosynthetic gene cluster for jerangolids Grant 7,285,405 - Reeves , et al. October 23, 2 | 2007-10-23 |
Macrolide antinfective agents Grant RE39,836 - Chu , et al. September 11, 2 | 2007-09-11 |
Geldanamycin compounds and method of use Grant 7,259,156 - Santi , et al. August 21, 2 | 2007-08-21 |
Polyketide synthase enzymes and recombinant DNA constructs therefor Grant RE39,762 - Reeves , et al. August 7, 2 | 2007-08-07 |
Sixteen-member macrolide antiinfective agents Grant 7,247,617 - Fu , et al. July 24, 2 | 2007-07-24 |
2-Desmethyl ansamycin compounds Grant 7,241,754 - Tian , et al. July 10, 2 | 2007-07-10 |
Secondary metabolite congener distribution modulation Grant 7,220,560 - Licari , et al. May 22, 2 | 2007-05-22 |
Synthetic discodermolide analogs Grant 7,214,708 - Sundermann , et al. May 8, 2 | 2007-05-08 |
9-Desoxoerythromycin compounds as prokinetic agents Grant 7,211,568 - Liu , et al. May 1, 2 | 2007-05-01 |
Recombinant polynucleotides encoding pro-geldanamycin producing polyketide synthase and accessory proteins, and uses thereof Grant 7,189,549 - Hutchinson , et al. March 13, 2 | 2007-03-13 |
Epothilone derivatives and methods for making and using the same Grant 7,176,235 - Ashley , et al. February 13, 2 | 2007-02-13 |
Transposon-based transformation system Grant 7,138,279 - Julien November 21, 2 | 2006-11-21 |
Recombinant methods and materials for producing epothilone and epothilone derivatives Grant 7,129,071 - Julien , et al. October 31, 2 | 2006-10-31 |
Production of polyketides App 20060223151 - Julien; Bryan ;   et al. | 2006-10-05 |
Therapeutic formulations Grant 7,091,193 - Sherrill , et al. August 15, 2 | 2006-08-15 |
Production of polyketides in bacteria and yeast Grant 7,078,233 - Barr , et al. July 18, 2 | 2006-07-18 |
Production of polyketides in bacteria and yeast App 20060148052 - Barr; Philip J. ;   et al. | 2006-07-06 |
Epothilone compounds and methods for making the same Grant 7,070,964 - Tang , et al. July 4, 2 | 2006-07-04 |
Method for production of polyketides Grant 7,067,290 - Regentin , et al. June 27, 2 | 2006-06-27 |
Cystobacterineae host cells containing heterologous PKS genes for the synthesis of polykedtides Grant 7,067,286 - Julien , et al. June 27, 2 | 2006-06-27 |
Multi-plasmid method for preparing large libraries of polyketides and non-ribosomal peptides Grant 7,049,100 - Santi , et al. May 23, 2 | 2006-05-23 |
Recombinant polyketide synthase genes Grant 7,033,818 - Hu , et al. April 25, 2 | 2006-04-25 |
Polyketides and antibiotics Grant 7,022,825 - Ashley , et al. April 4, 2 | 2006-04-04 |
Heterologous production of polyketides Grant 7,011,959 - Santi , et al. March 14, 2 | 2006-03-14 |
Methods of obtaining epothilone D using crystallization and /or by the culture of cells in the presence of methyl oleate Grant 6,998,256 - Arslanian February 14, 2 | 2006-02-14 |
Macrolide analogs Grant 6,984,515 - Khosla , et al. January 10, 2 | 2006-01-10 |
Ketolide anti-infective compounds App 20050272672 - Li, Yong ;   et al. | 2005-12-08 |
Pharmaceutical solution formulations containing 17-AAG App 20050256097 - Zhong, Ziyang ;   et al. | 2005-11-17 |
Biosynthetic gene cluster for jerangolids App 20050233369 - Reeves, Christopher ;   et al. | 2005-10-20 |
Synthetic genes App 20050227316 - Santi, Daniel ;   et al. | 2005-10-13 |
Combination therapies with epothilones and carboplatin App 20050215604 - Zhou, Yiqing ;   et al. | 2005-09-29 |
Motilide compounds Grant 6,946,482 - Santi , et al. September 20, 2 | 2005-09-20 |
Combination therapies using leptomycin B App 20050203174 - Santi, Daniel V. ;   et al. | 2005-09-15 |
Compounds useful for the synthesis of (+)-discodermolide and methods therefor App 20050197369 - Myles, David C. ;   et al. | 2005-09-08 |
Amido macrolides Grant 6,939,861 - Ashley , et al. September 6, 2 | 2005-09-06 |
Recombinant methods and materials for producing epothilone and epothilone derivatives Grant 6,921,650 - Julien , et al. July 26, 2 | 2005-07-26 |
Method of producing a compound by fermentation App 20050130283 - Leaf, Timothy A. ;   et al. | 2005-06-16 |
Recombinant narbonolide polyketide synthase Grant 6,902,913 - Betlach , et al. June 7, 2 | 2005-06-07 |
Biosynthetic gene cluster for leptomycins App 20050112726 - Hu, Zhihao ;   et al. | 2005-05-26 |
Epothilone derivatives and methods for making and using the same Grant 6,893,859 - Ashley , et al. May 17, 2 | 2005-05-17 |
11-o-methylgeldanamycin Compounds App 20050101656 - Tian, Zong-Qiang ;   et al. | 2005-05-12 |
11-O-methylgeldanamycin compounds Grant 6,887,993 - Tian , et al. May 3, 2 | 2005-05-03 |
Method for evaluating therapeutic efficacy Grant 6,875,576 - Carreras , et al. April 5, 2 | 2005-04-05 |
11-O-methylgeldanamycin compounds Grant 6,875,863 - Tian , et al. April 5, 2 | 2005-04-05 |
Benzoquinone ansamycins Grant 6,872,715 - Santi , et al. March 29, 2 | 2005-03-29 |
11-O-methylgeldanamycin compounds Grant 6,870,049 - Tian , et al. March 22, 2 | 2005-03-22 |
Method for treating diseases using HSP90-inhibiting agents in combination with nuclear export inhibitors App 20050054625 - Johnson, Robert JR. ;   et al. | 2005-03-10 |
Method for treating diseases using HSP90-inhibiting agents in combination with antibiotics App 20050054589 - Johnson, Robert JR. ;   et al. | 2005-03-10 |
Recombinant methods and materials for producing epothilone and epothilone derivatives Grant 6,858,411 - Julien , et al. February 22, 2 | 2005-02-22 |
11-O-methylgeldanamycin compounds Grant 6,855,705 - Tian , et al. February 15, 2 | 2005-02-15 |
Disorazole polyketide synthase encoding polynucleotides App 20050032184 - Julien, Bryan ;   et al. | 2005-02-10 |
Method for treating diseases using HSP90-inhibiting agents in combination with immunosuppressants App 20050026893 - Johnson, Robert JR. ;   et al. | 2005-02-03 |
Method for treating diseases using HSP90-inhibiting agents in combination with enzyme inhibitors App 20050020557 - Johnson, Robert JR. ;   et al. | 2005-01-27 |
Method for treating diseases using HSP90-inhibiting agents in combination with antimitotics App 20050020558 - Johnson, Robert JR. ;   et al. | 2005-01-27 |
Method for treating diseases using HSP90-inhibiting agents in combination with antimetabolites App 20050020534 - Johnson, Robert JR. ;   et al. | 2005-01-27 |
Method for treating diseases using HSP90-inhibiting agents in combination with platinum coordination complexes App 20050020556 - Johnson, Robert JR. ;   et al. | 2005-01-27 |
Overproduction hosts for biosynthesis of polyketides Grant 6,838,265 - Santi , et al. January 4, 2 | 2005-01-04 |
Transformation system based on the integrase gene and attachment site for Myxococcus xanthus bacteriophage Mx9 App 20040247620 - Julien, Bryan | 2004-12-09 |
Methods for introducing hydroxyl or epoxide groups into polyketides using OleP Grant 6,828,126 - McDaniel December 7, 2 | 2004-12-07 |
Laulimalide derivatives Grant 6,815,463 - Ashley , et al. November 9, 2 | 2004-11-09 |
Detection of modular polyketide synthase gene clusters App 20040209278 - Schirmer, Andreas ;   et al. | 2004-10-21 |
Macrolide antiinfective agents Grant 6,794,366 - Chu , et al. September 21, 2 | 2004-09-21 |
Macrolide antiinfective agents Grant 6,762,168 - Chu July 13, 2 | 2004-07-13 |
Polynucleotides encoding the fkbA gene of the FK-520 polyketide synthase gene cluster Grant 6,759,536 - Reeves , et al. July 6, 2 | 2004-07-06 |
Motilide compounds Grant 6,750,205 - Ashley , et al. June 15, 2 | 2004-06-15 |
Fermentation and purification of migrastatin and analog Grant 6,750,047 - Khosla , et al. June 15, 2 | 2004-06-15 |
Laulimalide derivatives Grant 6,670,389 - Ashley , et al. December 30, 2 | 2003-12-30 |
Polyketide synthase enzymes and recombinant DNA constructs therefor Grant 6,660,862 - Reeves , et al. December 9, 2 | 2003-12-09 |
Amido macrolides App 20030199458 - Ashley, Gary ;   et al. | 2003-10-23 |
Heterologous production of 15-methyl-6-deoxyerthronolide B Grant 6,627,427 - Katz , et al. September 30, 2 | 2003-09-30 |
Polyketide derivatives Grant 6,624,302 - Chu , et al. September 23, 2 | 2003-09-23 |
Epothilone compounds and methods for making and using the same Grant 6,589,968 - Arslanian , et al. July 8, 2 | 2003-07-08 |
Motilide compounds Grant 6,562,795 - Ashley , et al. May 13, 2 | 2003-05-13 |
Racemic thioesters for production of polyketides Grant 6,492,562 - Ashley , et al. December 10, 2 | 2002-12-10 |
Epothilone derivatives and methods for making and using the same Grant 6,489,314 - Ashley , et al. December 3, 2 | 2002-12-03 |
Ketolide antibacterials Grant 6,458,771 - Hlasta , et al. October 1, 2 | 2002-10-01 |
Myxococcus host cells for the production of epothilones Grant 6,410,301 - Julien , et al. June 25, 2 | 2002-06-25 |
Erythronolide compounds Grant 6,403,775 - McDaniel June 11, 2 | 2002-06-11 |
Multi-plasmid method for preparing large libraries of polyketides and non-ribosomal peptides Grant 6,399,789 - Santi , et al. June 4, 2 | 2002-06-04 |
Production of polyketides in plants Grant 6,262,340 - Betlach , et al. July 17, 2 | 2001-07-17 |
Recombinant narbonolide polyketide synthase Grant 6,117,659 - Ashley , et al. September 12, 2 | 2000-09-12 |
Production of polyketides in bacteria and yeast Grant 6,033,883 - Barr , et al. March 7, 2 | 2000-03-07 |
NCAGE Code | 46V22 | KOSAN BIOSCIENCES INCORPORATED |
CAGE Code | 46V22 | KOSAN BIOSCIENCES INCORPORATED |
SEC | 0001110206 | KOSAN BIOSCIENCES INC of CALIFORNIA |
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