Patent | Date |
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Ret Kinase Inhibitors App 20220144816 - Kolakowski; Gabrielle R. ;   et al. | 2022-05-12 |
Substituted Pyrazolo[1,5-a]pyrazine Compounds As Ret Kinase Inhibitors App 20220119396 - ANDREWS; Steven W. ;   et al. | 2022-04-21 |
Fused Heterocyclic Compounds As Ret Kinase Inhibitors App 20220112214 - BLAKE; James F. ;   et al. | 2022-04-14 |
Process For The Preparation Of 6-(2-hydroxy-2-methylpropoxy)-4-(6-(6-((6-methoxypyridin-3-yl)methyl)-3,6- -diazabicyclo[3.1.1]heptan-3-yl)pyridin-3-yl)pyrazolo[1,5-a]pyridine-3-car- Bonitrile App 20210380609 - EARY; Charles Todd ;   et al. | 2021-12-09 |
Compounds Useful For Inhibiting Ret Kinase App 20210363140 - ANDERSON; Erin D. ;   et al. | 2021-11-25 |
Substituted pyrazolo[1,5-a]pyrazines as RET kinase inhibitors Grant 11,168,090 - Andrews , et al. November 9, 2 | 2021-11-09 |
Process for the preparation of 6-(2-hydroxy-2-methylpropoxy)-4-(6-(6-((6-methoxypyridin-3-yl)methyl)-3,6- -diazabicyclo[3.1.1]heptan-3-yl)pyridin-3-yl)pyrazolo[1,5-a]pyridine-3-car- bontrile Grant 11,098,064 - Eary , et al. August 24, 2 | 2021-08-24 |
Substituted Pyrazolo[1,5-a]pyridine Compounds As Ret Kinase Inhibitors App 20210186959 - Andrews; Steven W. ;   et al. | 2021-06-24 |
Point Mutations In Trk Inhibitor-resistant Cancer And Methods Relating To The Same App 20210164055 - Nanda; Nisha ;   et al. | 2021-06-03 |
Macrocyclic compounds as ROS1 kinase inhibitors Grant 10,966,985 - Andrews , et al. April 6, 2 | 2021-04-06 |
Substituted pyrazolo[1,5-a]pyridine compounds as RET kinase inhibitors Grant 10,953,005 - Andrews , et al. March 23, 2 | 2021-03-23 |
Point mutations in TRK inhibitor-resistant cancer and methods relating to the same Grant 10,907,215 - Nanda , et al. February 2, 2 | 2021-02-02 |
Bicyclic urea, thiourea, guanidine and cyanoguanidine compounds useful for the treatment of pain Grant 10,889,589 - Allen , et al. January 12, 2 | 2021-01-12 |
Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors Grant 10,881,652 - Andrews , et al. January 5, 2 | 2021-01-05 |
SUBSTITUTED PYRAZOLO[3,4-d]PYRIMIDINE COMPOUNDS AS RET KINASE INHIBITORS App 20200399279 - BLAKE; James F. ;   et al. | 2020-12-24 |
Substituted Pyrazolo[1,5-a]pyridine Compounds As Ret Kinase Inhibitors App 20200383966 - ANDREWS; Steven W. ;   et al. | 2020-12-10 |
Methods of treatment using pyrrolidinyl urea, thiourea, guanidine and cyanoguanidine compounds Grant 10,851,080 - Allen , et al. December 1, 2 | 2020-12-01 |
Substituted Pyrrolo[2,3-d]pyrimidines Compounds As Ret Kinase Inhibitors App 20200339589 - BLAKE; James F. ;   et al. | 2020-10-29 |
Substituted Pyrazolyl[4,3-c]pyridine Compounds As Ret Kinase Inhibitors App 20200339579 - WALLS; Shane M. ;   et al. | 2020-10-29 |
Process For The Preparation Of 6-(2-hydroxy-2-methylpropoxy)-4-(6-(6-((6-methoxypyridin-3-yl)methyl)-3,6- -diazabicyclo[3.1.1]heptan-3-yl)pyridin-3-yl)pyrazolo[1,5-a]pyridine-3-car- Bonitrile App 20200308194 - EARY; Charles Todd ;   et al. | 2020-10-01 |
Macrocyclic Compounds As Trk Kinase Inhibitors App 20200291026 - Andrews; Steven W. ;   et al. | 2020-09-17 |
Process for the preparation of 6-(2-hydroxy-2-methylpropoxy)-4-(6-(6-((6-methoxypyridin-3-yl)methyl)-3,6- -diazabicyclo[3.1.1]heptan-3-yl)pyridin-3-yl)pyrazolo[1,5-a]pyridine-3-car- bonitrile Grant 10,745,419 - Eary , et al. A | 2020-08-18 |
Point mutations in TRK inhibitor-resistant cancer and methods relating to the same Grant 10,724,102 - Nanda , et al. | 2020-07-28 |
Macrocylic compounds as ROS1 kinase inhibitors Grant 10,688,100 - Andrews , et al. | 2020-06-23 |
Point mutations in TRK inhibitor-resistant cancer and methods relating to the same Grant 10,655,186 - Nanda , et al. | 2020-05-19 |
Macrocyclic compounds as TRK kinase inhibitors Grant 10,647,730 - Andrews , et al. | 2020-05-12 |
Crystalline forms Grant 10,584,124 - Metcalf , et al. | 2020-03-10 |
Substituted Pyrazolo[1,5-a]pyrazine Compounds As Ret Kinase Inhibitors App 20200055860 - ANDREWS; Steven W ;   et al. | 2020-02-20 |
Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors Grant 10,555,944 - Andrews , et al. Feb | 2020-02-11 |
Substituted Pyrazolo[1,5-a]pyridine Compounds As Ret Kinase Inhibitors App 20200030311 - ANDREWS; Steven W. ;   et al. | 2020-01-30 |
Pyrrolidinyl Urea, Pyrrolidinyl Thiourea And Pyrrolidinyl Guanidine Compounds As Trka Kinase Inhibitors App 20190359597 - Allen; Shelley ;   et al. | 2019-11-28 |
Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors Grant 10,441,581 - Andrews , et al. Oc | 2019-10-15 |
Bicyclic Urea, Thiourea, Guanidine And Cyanoguanidine Compounds Useful For The Treatment Of Pain App 20190270749 - Allen; Shelley ;   et al. | 2019-09-05 |
Crystalline Forms App 20190263811 - Metcalf; Andrew T. ;   et al. | 2019-08-29 |
Point mutations in TRK inhibitor-resistant cancer and methods relating to the same Grant 10,378,068 - Nanda , et al. A | 2019-08-13 |
Point mutations in TRK inhibitor-resistant cancer and methods relating to the same Grant 10,370,727 - Nanda , et al. | 2019-08-06 |
Bicyclic urea, thiourea, guanidine and cyanoguanidine compounds useful for the treatment of pain Grant 10,351,575 - Allen , et al. July 16, 2 | 2019-07-16 |
Substituted Pyrazolo[1,5-a]pyridine Compounds As Ret Kinase Inhibitors App 20190183886 - Andrews; Steven W. ;   et al. | 2019-06-20 |
Pyrrolidinyl urea, pyrrolidinyl thiourea and pyrrolidinyl guanidine compounds as TrkA kinase inhibitors Grant 10,323,022 - Allen , et al. | 2019-06-18 |
Macrocyclic Compounds As Ros1 Kinase Inhibitors App 20190151322 - Andrews; Steven W. ;   et al. | 2019-05-23 |
Substituted Pyrazolo[1,5-a]pyridine Compounds As Ret Kinase Inhibitors App 20190127374 - Andrews; Steven W. ;   et al. | 2019-05-02 |
Substituted Pyrazolo[1,5-a]pyridine Compounds As Ret Kinase Inhibitors App 20190127375 - Andrews; Steven W. ;   et al. | 2019-05-02 |
Substituted Pyrazolo[1,5-a]pyridine Compounds As Ret Kinase Inhibitors App 20190127373 - Andrews; Steven W. ;   et al. | 2019-05-02 |
Process For The Preparation Of 6-(2-hydroxy-2-methylpropoxy)-4-(6-(6-((6-methoxypyridin-3-yl)methyl)-3,6- -diazabicyclo[3.1.1]heptan-3-yl)pyridin-3-yl)pyrazolo[1,5-a]pyridine-3-car- Bonitrile App 20190106438 - Eary; Charles Todd ;   et al. | 2019-04-11 |
Macrocyclic Compounds As Ros1 Kinase Inhibitors App 20190076437 - Andrews; Steven W. ;   et al. | 2019-03-14 |
Macrocyclic Compounds As Ros1 Kinase Inhibitors App 20190076436 - Andrews; Steven W. ;   et al. | 2019-03-14 |
Macrocyclic Compounds As Trk Kinase Inhibitors App 20190031684 - Andrews; Steven W. ;   et al. | 2019-01-31 |
Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors Grant 10,172,851 - Andrews , et al. J | 2019-01-08 |
Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors Grant 10,172,845 - Andrews , et al. J | 2019-01-08 |
Substituted pyrazolo[1,5-a]pyridine compounds as RET kinase inhibitors Grant 10,174,027 - Andrews , et al. J | 2019-01-08 |
Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors Grant 10,174,028 - Andrews , et al. J | 2019-01-08 |
Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors Grant 10,144,734 - Andrews , et al. De | 2018-12-04 |
Substituted pyrazolo[1,5-a]pyridine compounds as RET kinase inhibitors Grant 10,138,243 - Andrews , et al. Nov | 2018-11-27 |
Substituted pyrazolo[1,5-a]pyridine compounds as RET kinase inhibitors Grant 10,137,124 - Andrews , et al. November 27, 2 | 2018-11-27 |
Pyrrolidinyl Urea, Pyrrolidinyl Thiourea And Pyrrolidinyl Guanidine Compounds As Trka Kinase Inhibitors App 20180334450 - Allen; Shelley ;   et al. | 2018-11-22 |
Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors Grant 10,112,942 - Andrews , et al. October 30, 2 | 2018-10-30 |
Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors Grant 10,023,570 - Andrews , et al. July 17, 2 | 2018-07-17 |
Substituted Pyrazolo[1,5-a]pyridine Compounds As Ret Kinase Inhibitors App 20180186791 - Andrews; Steven W. ;   et al. | 2018-07-05 |
Substituted Pyrazolo[1,5-a]pyridine Compounds As Ret Kinase Inhibitors App 20180186790 - Andrews; Steven W. ;   et al. | 2018-07-05 |
Substituted Pyrazolo[1,5-a]pyridine Compounds As Ret Kinase Inhibitors App 20180179203 - Andrews; Steven W. ;   et al. | 2018-06-28 |
Methods Of Treatment Using Pyrrolidinyl Urea, Thiourea, Guanidine And Cyanoguanidine Compounds App 20180179182 - Allen; Shelley ;   et al. | 2018-06-28 |
Substituted Pyrazolo[1,5-a]pyridine Compounds As Ret Kinase Inhibitors App 20180148445 - Andrews; Steven W. ;   et al. | 2018-05-31 |
Thiazolyl and oxazolyl urea, thiourea, guanidine and cyanoguanidine compounds as TrkA kinase inhibitors Grant 9,981,959 - Brandhuber , et al. May 29, 2 | 2018-05-29 |
Point Mutations In Trk Inhibitor-resistant Cancer And Methods Relating To The Same App 20180142306 - Nanda; Nisha ;   et al. | 2018-05-24 |
Substituted Pyrazolo[1,5-a]pyridine Compounds As Ret Kinase Inhibitors App 20180133207 - Andrews; Steven W. ;   et al. | 2018-05-17 |
Substituted Pyrazolo[1,5-a]pyridine Compounds As Ret Kinase Inhibitors App 20180133213 - Andrews; Steven W. ;   et al. | 2018-05-17 |
Substituted Pyrazolo[1,5-a]pyridine Compounds As Ret Kinase Inhibitors App 20180134702 - Andrews; Steven W. ;   et al. | 2018-05-17 |
Substituted Pyrazolo[1,5-a]pyridine Compounds As Ret Kinase Inhibitors App 20180134703 - Andrews; Steven W. ;   et al. | 2018-05-17 |
Substituted Pyrazolo[1,5-a]pyridine Compounds As Ret Kinase Inhibitors App 20180133200 - Andrews; Steven W. ;   et al. | 2018-05-17 |
Point Mutations In Trk Inhibitor-resistant Cancer And Methods Relating To The Same App 20180119228 - Nanda; Nisha ;   et al. | 2018-05-03 |
Macrocyclic compounds as TRK kinase inhibitors Grant 9,902,741 - Andrews , et al. February 27, 2 | 2018-02-27 |
N-pyrrolidinyl,N'-pyrazolyl-urea, thiourea, guanidine and cyanoguanidine compounds as TrkA kinase inhibitors Grant 9,896,435 - Allen , et al. February 20, 2 | 2018-02-20 |
Point Mutations In Trk Inhibitor-resistant Cancer And Methods Relating To The Same App 20180030549 - Nanda; Nisha ;   et al. | 2018-02-01 |
Point Mutations In Trk Inhibitor-resistant Cancer And Methods Relating To The Same App 20180030548 - Nanda; Nisha ;   et al. | 2018-02-01 |
Pyrrolidinyl urea, pyrrolidinyl thiourea and pyrrolidinyl guanidine compounds as TrkA kinase inhibitors Grant 9,878,997 - Allen , et al. January 30, 2 | 2018-01-30 |
Macrocyclic compounds as TRK kinase inhibitors Grant 9,840,519 - Andrews , et al. December 12, 2 | 2017-12-12 |
Pyrrolidinyl urea, thiourea, guanidine and cyanoguanidine compounds as TrkA kinase inhibitors Grant 9,828,360 - Allen , et al. November 28, 2 | 2017-11-28 |
Pyrazolyl urea, thiourea, guanidine and cyanoguanidine compounds as trkA kinase inhibitors Grant 9,809,578 - Brandhuber , et al. November 7, 2 | 2017-11-07 |
Macrocyclic Compounds As Trk Kinase Inhibitors App 20170283435 - Andrews; Steven W. ;   et al. | 2017-10-05 |
Point Mutations In Trk Inhibitor-resistant Cancer And Methods Relating To The Same App 20170260589 - Nanda; Nisha ;   et al. | 2017-09-14 |
Macrocyclic compounds as Trk kinase inhibitors Grant 9,750,744 - Andrews , et al. September 5, 2 | 2017-09-05 |
Pyrrolidinyl Urea, Pyrrolidinyl Thiourea And Pyrrolidinyl Guanidine Compounds As Trka Kinase Inhibitors App 20170217936 - Allen; Shelley ;   et al. | 2017-08-03 |
Macrocyclic compounds as Trk kinase inhibitors Grant 9,718,822 - Andrews , et al. August 1, 2 | 2017-08-01 |
Macrocyclic Compounds As Trk Kinase Inhibitors App 20170112842 - Andrews; Steven W. ;   et al. | 2017-04-27 |
Macrocyclic Compounds As Trk Kinase Inhibitors App 20170114059 - Andrews; Steven W. ;   et al. | 2017-04-27 |
Macrocyclic Compounds As Trk Kinase Inhibitors App 20170107232 - Andrews; Steven W. ;   et al. | 2017-04-20 |
Substituted Pyrazolo[1,5-a]pyridine Compounds As Ret Kinase Inhibitors App 20170096425 - Andrews; Steven W. ;   et al. | 2017-04-06 |
Pyrrolidinyl urea, pyrrolidinyl thiourea and pyrrolidinyl guanidine compounds as TrkA kinase inhibitors Grant 9,562,055 - Allen , et al. February 7, 2 | 2017-02-07 |
N-bicyclic aryl,N'-pyrazolyl urea, thiourea, guanidine cyanoguanidine compounds as TrkA kinase inhibitors Grant 9,546,156 - Allen , et al. January 17, 2 | 2017-01-17 |
Bicyclic Urea, Thiourea, Guanidine And Cyanoguanidine Compounds Useful For The Treatment Of Pain App 20160355521 - Allen; Shelley ;   et al. | 2016-12-08 |
Macrocyclic compounds as trk kinase inhibitors Grant 9,493,476 - Andrews , et al. November 15, 2 | 2016-11-15 |
Pyrrolidinyl Urea, Thiourea, Guanidine And Cyanoguanidine Compounds As Trka Kinase Inhibitors App 20160297796 - Allen; Shelley ;   et al. | 2016-10-13 |
Pyrazolyl Urea, Thiourea, Guanidine And Cyanoguanidine Compounds As Trka Kinase Inhibitors App 20160280690 - Brandhuber; Barbara J. ;   et al. | 2016-09-29 |
Thiazolyl And Oxazolyl Urea, Thiourea, Guanidine And Cyanoguanidine Compounds As Trka Kinase Inhibitors App 20160280702 - Brandhuber; Barbara J. ;   et al. | 2016-09-29 |
N-bicyclic Aryl,n'-pyrazolyl Urea, Thiourea, Guanidine And Cyanoguanidine Compounds As Trka Kinase Inhibitors App 20160280681 - Allen; Shelley ;   et al. | 2016-09-29 |
N-pyrrolidinyl,n'-pyrazolyl-urea, Thiourea, Guanidine And Cyanoguanidine Compounds As Trka Kinase Inhibitors App 20160280682 - Allen; Shelley ;   et al. | 2016-09-29 |
Macrocyclic Compounds As Trk Kinase Inhibitors App 20150336970 - Andrews; Steven Wade ;   et al. | 2015-11-26 |
Serine/threonine kinase inhibitors Grant 9,133,187 - Blake , et al. September 15, 2 | 2015-09-15 |
Pyrrolidinyl Urea, Pyrrolidinyl Thiourea And Pyrrolidinyl Guanidine Compounds As Trka Kinase Inhibitors App 20150166564 - Allen; Shelley ;   et al. | 2015-06-18 |
Macrocyclic compounds as Trk kinase inhibitors Grant 8,933,084 - Andrews , et al. January 13, 2 | 2015-01-13 |
Serine/threonine Kinase Inhibitors App 20130338140 - Blake; James F. ;   et al. | 2013-12-19 |
Macrocyclic Compounds As Trk Kinase Inhibitors App 20130203776 - Andrews; Steven Wade ;   et al. | 2013-08-08 |