Patent | Date |
---|
Macrocyclic MCL-1 Inhibitors and Methods of Use App 20200325153 - Judd; Andrew S. ;   et al. | 2020-10-15 |
Macrocyclic Mcl-1 Inhibitors And Methods Of Use App 20200255451 - Kind Code | 2020-08-13 |
Macrocyclic Mcl-1 Inhibitors And Methods Of Use App 20200239494 - BRAJE; Wilfried ;   et al. | 2020-07-30 |
Proline Amide Compounds And Their Azetidine Analogues Carrying A Specifically Substituted Benzyl Radical App 20200039930 - Backfisch; Gisela ;   et al. | 2020-02-06 |
Macrocyclic MCL-1 inhibitors and methods of use App 20190144465 - Judd; Andrew S. ;   et al. | 2019-05-16 |
Pyridyl Or Pyrazinyl Compounds Carrying A Methyl-bound Alpha-amino Acid Amide Group App 20190062305 - BACKFISCH; Gisela ;   et al. | 2019-02-28 |
Oxindole derivatives carrying an amine-substituted piperidyl-acetidinyl substituent and use thereof for treating vasopressine-related diseases Grant 9,862,704 - Geneste , et al. January 9, 2 | 2018-01-09 |
Oxindole derivatives carrying a piperidyl-substituted azetidinyl substituent and use thereof for treating vasopressine-related diseases Grant 9,840,495 - Geneste , et al. December 12, 2 | 2017-12-12 |
Oxindole compounds carrying a nitrogen-bound spiro substituent and use thereof for treating vasopressin-related diseases Grant 9,688,678 - Geneste , et al. June 27, 2 | 2017-06-27 |
Oxindole derivatives carrying an oxetane substituent and use thereof for treating vassopressin-related diseases Grant 9,657,002 - Jantos , et al. May 23, 2 | 2017-05-23 |
Fused heterocyclic or carbocyclic compounds carrying a substituted cycloaliphatic radical and use thereof for treating vasopressin-related diseases Grant 9,617,226 - Braje , et al. April 11, 2 | 2017-04-11 |
Carboxamide compounds and their use as calpain inhibitors Grant 9,567,325 - Kling , et al. February 14, 2 | 2017-02-14 |
Guanidine Compounds And Use Thereof As Binding Partners For 5-ht5 Receptors App 20170037016 - Netz; Astrid ;   et al. | 2017-02-09 |
Oxindole Derivatives Carrying A Piperidyl-substituted Azetidinyl Substituent And Use Thereof For Treating Vasopressine-related Diseases App 20170008875 - GENESTE; Herve ;   et al. | 2017-01-12 |
Oxindole Derivatives Carrying An Amine-substituted Piperidyl-azetidinyl Substituent And Use Thereof For Treating Vasopressine-related Diseases App 20170001982 - GENESTE; Herve ;   et al. | 2017-01-05 |
Carboxamide compounds and their use as calpain inhibitors Grant 9,527,811 - Mack , et al. December 27, 2 | 2016-12-27 |
Oxindole compounds carrying a CO-bound spiro substituent and use thereof for treating vasopressin-related diseases Grant 9,527,856 - Braje , et al. December 27, 2 | 2016-12-27 |
Guanidine compounds, and use thereof as binding partners for 5-HT5 receptors Grant 9,475,782 - Netz , et al. October 25, 2 | 2016-10-25 |
Oxindole Derivatives Carrying An Oxetane Substituent Anduse Thereof For Treating Vasopressin-related Diseases App 20160168135 - Jantos; Katja ;   et al. | 2016-06-16 |
Hetaryl-substituted guanidine compounds and use thereof as binding partners for 5-HT.sub.5-receptors Grant 9,296,697 - Amberg , et al. March 29, 2 | 2016-03-29 |
Fused Heterocyclic Or Carbocyclic Compounds Carrying A Substituted Cycloaliphatic Radical And Use Thereof For Treating Vasopressin-related Diseases App 20160068494 - Braje; Wilfried ;   et al. | 2016-03-10 |
Oxindole derivatives carrying an oxetane substituent and use thereof for treating vasopressine-related diseases Grant 9,273,036 - Jantos , et al. March 1, 2 | 2016-03-01 |
Oxindole Compounds Carrying A Co-bound Spiro Substituent And Use Thereof For Treating Vasopressin-related Diseases App 20150344489 - Braje; Wilfried ;   et al. | 2015-12-03 |
Oxindole Compounds Carrying A Nitrogen-bound Spiro Substituent And Use Thereof For Treating Vasopressin-related Diseases App 20150329551 - Geneste; Herve ;   et al. | 2015-11-19 |
Carboxamide compounds and their use as calpain inhibitors V Grant 9,150,545 - Kling , et al. October 6, 2 | 2015-10-06 |
Carboxamide compounds and their use as calpain inhibitors Grant 9,150,553 - Hornberger , et al. October 6, 2 | 2015-10-06 |
Carboxamide compounds and their use as calpain inhibitors Grant 9,139,557 - Kling , et al. September 22, 2 | 2015-09-22 |
Carboxamide Compounds And Their Use As Calpain Inhibitors V App 20150252017 - Kling; Andreas ;   et al. | 2015-09-10 |
Aminotetraline derivatives, pharmaceutical compositions containing them, and their use in therapy Grant 9,096,619 - Amberg , et al. August 4, 2 | 2015-08-04 |
5-ring Heteroaromatic Compounds And Their Use As Binding Partners For 5-ht5 Receptors App 20150183770 - Amberg; Wilhelm ;   et al. | 2015-07-02 |
Aminotetraline derivatives, pharmaceutical compositions containing them, and their use in therapy Grant 9,067,871 - Amberg , et al. June 30, 2 | 2015-06-30 |
Carboxamide compounds and their use as calpain inhibitors V Grant 9,062,027 - Kling , et al. June 23, 2 | 2015-06-23 |
Carboxamide compounds and their use as calpain inhibitors V Grant 9,051,304 - Kling , et al. June 9, 2 | 2015-06-09 |
Carboxamide compounds and their use as calpain inhibitors Grant 9,018,206 - Mack , et al. April 28, 2 | 2015-04-28 |
Carboxamide Compounds And Their Use As Calpain Inhibitors App 20150099786 - Mack; Helmut ;   et al. | 2015-04-09 |
Carboxamide Compounds And Their Use As Calpain Inhibitors V App 20150065477 - Kling; Andreas ;   et al. | 2015-03-05 |
Carboxamide Compounds And Their Use As Calpain Inhibitors App 20150045394 - Kling; Andreas ;   et al. | 2015-02-12 |
5-ring heteroaromatic compounds and their use as binding partners for 5-HT5 receptors Grant 8,921,406 - Amberg , et al. December 30, 2 | 2014-12-30 |
5-ring heteroaromatic compounds and their use as binding partners for 5-HT5 receptors Grant 08921406 - | 2014-12-30 |
Carboxamide compounds and their use as calpain inhibitors Grant 8,906,941 - Kling , et al. December 9, 2 | 2014-12-09 |
Oxindole Derivatives Carrying An Oxetane Substituent and use thereof for Treating Vasopressine-Related Diseases App 20140343074 - Jantos; Katja ;   et al. | 2014-11-20 |
Oxindole Derivatives Carrying An Oxetane Substituent and Use Thereof For Treating Vassopressin-Related Diseases App 20140315918 - Jantos; Katja ;   et al. | 2014-10-23 |
Heterocyclic Compounds And Their Use As Binding Partners For 5-ht5 Receptors App 20140221371 - Amberg; Wilhelm ;   et al. | 2014-08-07 |
Carboxamide Compounds And Their Use As Calpain Inhibitors Iv App 20140179702 - Kling; Andreas ;   et al. | 2014-06-26 |
Heterocyclic compounds and their use as binding partners for 5-HT.sub.5 receptors Grant 8,686,002 - Amberg , et al. April 1, 2 | 2014-04-01 |
Aminotetraline Derivatives, Pharmaceutical Compositions Containing Them, And Their Use In Therapy App 20140031331 - Amberg; Wilhelm ;   et al. | 2014-01-30 |
Carboxamide Compounds And Their Use As Calpain Inhibitors V App 20140005227 - Kling; Andreas ;   et al. | 2014-01-02 |
Guanidine Compounds, And Use Thereof As Binding Partners For 5-ht5 Receptors App 20130324537 - Netz; Astrid ;   et al. | 2013-12-05 |
Carboxamide compounds and their use as calpain inhibitors IV Grant 8,598,211 - Kling , et al. December 3, 2 | 2013-12-03 |
Novel Carboxylic Acid Derivatives, Their Preparation And Use App 20130317044 - Riechers; Hartmut ;   et al. | 2013-11-28 |
Aminotetraline derivatives, pharmaceutical compositions containing them, and their use in therapy Grant 8,563,617 - Amberg , et al. October 22, 2 | 2013-10-22 |
Carboxamide Compounds And Their Use As Calpain Inhibitors App 20130245003 - Kling; Andreas ;   et al. | 2013-09-19 |
Aminotetraline Derivatives, Pharmaceutical Compositions Containing Them, And Their Use In Therapy App 20130184238 - Amberg; Wilhelm ;   et al. | 2013-07-18 |
Guanidine compounds, and use thereof as binding partners for 5-HT5 receptors Grant 8,481,576 - Netz , et al. July 9, 2 | 2013-07-09 |
Carboxamide Compounds And Their Use As Calpain Inhibitors App 20130150367 - Mack; Helmut ;   et al. | 2013-06-13 |
Antineoplastic peptides Grant 8,440,626 - Amberg , et al. May 14, 2 | 2013-05-14 |
Carboxamide compounds and their use as calpain inhibitors Grant 8,436,034 - Kling , et al. May 7, 2 | 2013-05-07 |
Guanidine compounds, and use thereof as binding partners for 5-HT5 receptors Grant 8,431,604 - Netz , et al. April 30, 2 | 2013-04-30 |
Dolastatin 15 Derivatives App 20130046077 - JANSSEN; Bernd ;   et al. | 2013-02-21 |
Carboxylic acid derivatives, their preparation and use Grant 8,349,843 - Riechers , et al. January 8, 2 | 2013-01-08 |
Carboxamide compounds and their use as calpain inhibitors Grant 8,283,363 - Mack , et al. October 9, 2 | 2012-10-09 |
Carboxamide compounds and their use as calpain inhibitors Grant 8,236,798 - Mack , et al. August 7, 2 | 2012-08-07 |
Dolastatin 15 derivatives Grant 8,163,698 - Janssen , et al. April 24, 2 | 2012-04-24 |
Novel Carboxylic Acid Derivatives, Their Preparation And Use App 20120088911 - Riechers; Hartmut ;   et al. | 2012-04-12 |
Guanidine Compounds, And Use Thereof As Binding Partners For 5-ht5 Receptors App 20110237589 - Netz; Astrid ;   et al. | 2011-09-29 |
Pyrimidin-2-one compounds and their use as dopamine D.sub.3 receptor ligands Grant 8,008,488 - Geneste , et al. August 30, 2 | 2011-08-30 |
5-Ring Heteroaromatic compounds and their use as binding partners for 5-ht5 receptors App 20110207788 - Amberg; Wilhelm ;   et al. | 2011-08-25 |
Novel Carboxylic Acid Derivatives, Their Preparation And Use App 20110178294 - Riechers; Hartmut ;   et al. | 2011-07-21 |
Carboxamide Compounds And Their Use As Calpain Inhibitors V App 20110152265 - Kling; Andreas ;   et al. | 2011-06-23 |
Carboxamide Compounds And Their Use As Calpain Inhibitors Iv App 20110152325 - Kling; Andreas ;   et al. | 2011-06-23 |
Carboxylic acid derivatives, their preparation and use Grant RE42,477 - Riechers , et al. June 21, 2 | 2011-06-21 |
Carboxylic acid derivatives, their preparation and use Grant RE42,462 - Riechers , et al. June 14, 2 | 2011-06-14 |
Antineoplastic Peptides App 20110098235 - AMBERG; Wilhelm ;   et al. | 2011-04-28 |
Carboxamide Compounds And Their Use As Calpain Inhibitors App 20110086879 - Mack; Helmut ;   et al. | 2011-04-14 |
Carboxamide Compounds And Their Use As Calpain Inhibitors App 20110059968 - Hornberger; Wilfried ;   et al. | 2011-03-10 |
Carboxylic acid derivatives, their preparation and use Grant 7,863,445 - Riechers , et al. January 4, 2 | 2011-01-04 |
Carboxamide compounds and their use as calpain inhibitors App 20100298326 - Kling; Andreas ;   et al. | 2010-11-25 |
Carboxamide Compounds And Their Use As Calpain Inhibitors App 20100286146 - Mack; Helmut ;   et al. | 2010-11-11 |
Antineoplastic peptides Grant 7,807,779 - Amberg , et al. October 5, 2 | 2010-10-05 |
Carboxamide compounds and their use as calpain inhibitors Grant 7,799,809 - Kling , et al. September 21, 2 | 2010-09-21 |
Carboxamide compounds and their use as calpain inhibitors App 20100216844 - Kling; Andreas ;   et al. | 2010-08-26 |
Heataryl-substituted guanidine compounds and use thereof as binding partners for 5-ht5-receptors App 20100184787 - Amberg; Wilhelm ;   et al. | 2010-07-22 |
Carboxamide compounds and their use as calpain inhibitors Grant 7,728,012 - Kling , et al. June 1, 2 | 2010-06-01 |
Dolastatin 15 Derivatives App 20100099843 - JANSSEN; Bernd ;   et al. | 2010-04-22 |
Novel Carboxylic Acid Derivatives, Their Preparation And Use App 20100076188 - Riechers; Hartmut ;   et al. | 2010-03-25 |
Novel Substituted Diaryl Azepine Derivatives as Integrin Ligands App 20100048536 - Geneste; Herve ;   et al. | 2010-02-25 |
Heterocyclic Compounds And Their Use As Binding Partners For 5-ht5 Receptors App 20100041698 - Amberg; Wilhelm ;   et al. | 2010-02-18 |
Dolastatin 15 derivatives Grant 7,662,786 - Janssen , et al. February 16, 2 | 2010-02-16 |
Inhibitors of the endothelin signalling pathway and alphavbeta3 integrin receptor antagonists for combination therapy App 20090311266 - Amberg; Wilhelm ;   et al. | 2009-12-17 |
Carboxylic acid derivatives, their preparation and use Grant 7,601,730 - Riechers , et al. October 13, 2 | 2009-10-13 |
Carboxylic acid derivatives, their preparation and use Grant 7,582,647 - Riechers , et al. September 1, 2 | 2009-09-01 |
3-Substituted 3,4-dihydro-thieno[2,3-d]pyrimidin-4-one derivatives, production and use thereof Grant 7,491,729 - Bakker , et al. February 17, 2 | 2009-02-17 |
Carboxamide compounds and their use as calpain inhibitors App 20080234329 - Kling; Andreas ;   et al. | 2008-09-25 |
Carboxamide compounds and their use as calpain inhibitors App 20080234330 - Kling; Andreas ;   et al. | 2008-09-25 |
Antineoplastic peptides App 20080234205 - Amberg; Wilhelm ;   et al. | 2008-09-25 |
Ligands of Integrin Receptors App 20080221082 - Geneste; Herve ;   et al. | 2008-09-11 |
Antineoplastic peptides Grant 7,368,528 - Amberg , et al. May 6, 2 | 2008-05-06 |
Guanidine Compounds, and Use Thereof as Binding partners for 5-Ht5 Receptors App 20070299074 - Netz; Astrid ;   et al. | 2007-12-27 |
Integrin ligands Grant 7,279,468 - Geneste , et al. October 9, 2 | 2007-10-09 |
Novel carboxylic acid derivatives, their preparation and use App 20070203338 - Riechers; Hartmut ;   et al. | 2007-08-30 |
Novel carboxylic acid derivatives, their preparation and use App 20060276474 - Riechers; Hartmut ;   et al. | 2006-12-07 |
Novel carboxylic acid derivatives, their preparation and use App 20060276645 - Riechers; Hartmut ;   et al. | 2006-12-07 |
Dolastatin 15 derivatives App 20060270606 - Janssen; Bernd ;   et al. | 2006-11-30 |
Integrin receptor ligands Grant 7,125,883 - Zechel , et al. October 24, 2 | 2006-10-24 |
Pyrimidin-2-one compounds and their use as dopamine d3 receptor ligands App 20060235004 - Geneste; Herve ;   et al. | 2006-10-19 |
Carboxylic acid derivatives, their preparation and their use Grant 7,119,097 - Riechers , et al. October 10, 2 | 2006-10-10 |
Carboxylic acid derivatives, their preparation and use Grant 7,109,205 - Riechers , et al. September 19, 2 | 2006-09-19 |
Integrin receptors antagonists Grant 7,105,508 - Kling , et al. September 12, 2 | 2006-09-12 |
Dolastatin 15 derivatives Grant 7,084,110 - Janssen , et al. August 1, 2 | 2006-08-01 |
New carboxylic acid derivatives, their preparation and their use App 20060160808 - Riechers; Hartmut ;   et al. | 2006-07-20 |
3-Substituted 3,4-dihydro-thieno[2,3-d]pyrimidin-4-one derivatives, production and use thereof App 20060142317 - Bakker; Margaretha ;   et al. | 2006-06-29 |
Antineoplastic peptides App 20060009392 - Amberg; Wilhelm ;   et al. | 2006-01-12 |
Substituted pyrimidinone derivatives as ligands of integrin receptors App 20040259864 - Geneste, Herve ;   et al. | 2004-12-23 |
Novel carboxylic acid derivatives, their preparation and use App 20040092742 - Riechers, Hartmut ;   et al. | 2004-05-13 |
Novel integrin receptor antagonists App 20040077638 - Geneste, Herve ;   et al. | 2004-04-22 |
Integrin ligands App 20040063934 - Geneste, Herve ;   et al. | 2004-04-01 |
.alpha.-hydrdroxylic acid derivatives, their production and use Grant 6,686,369 - Klinge , et al. February 3, 2 | 2004-02-03 |
Low molecular weight inhibitors of complement proteases Grant 6,683,055 - Hillen , et al. January 27, 2 | 2004-01-27 |
Azinyloxy, and phenoxy-diaryl-carboxylic acid derivatives, their preparation and use as mixed ETA/ETB endothelin receptor antagonists Grant 6,670,367 - Amberg , et al. December 30, 2 | 2003-12-30 |
Pyrimidinonesulfamoylureas` App 20030171368 - Seitz, Werner ;   et al. | 2003-09-11 |
Carboxylic acid derivatives, their production and use Grant 6,610,691 - Riechers , et al. August 26, 2 | 2003-08-26 |
Dolastatin 15 derivatives App 20030153505 - Janssen, Bernd ;   et al. | 2003-08-14 |
Carboxylic acid derivatives, their preparation and use Grant 6,600,043 - Riechers , et al. July 29, 2 | 2003-07-29 |
Dolastatin 15 derivatives Grant 6,458,765 - Janssen , et al. October 1, 2 | 2002-10-01 |
Novel carboxylic acid derivatives, their preparation and use App 20020052495 - Riechers, Hartmut ;   et al. | 2002-05-02 |
Dolastatin peptides Grant 6,323,315 - Pettit , et al. November 27, 2 | 2001-11-27 |
Dolastatin 15 derivatives App 20010018422 - Ritter, Kurt ;   et al. | 2001-08-30 |
Antineoplastic peptides App 20010009901 - Amberg, Wilhelm ;   et al. | 2001-07-26 |
Compounds useful for the synthesis of dolastatin analogs Grant 6,248,865 - Amberg , et al. June 19, 2 | 2001-06-19 |
Carboxylic acid derivatives, their preparation and use Grant 6,197,958 - Riechers , et al. March 6, 2 | 2001-03-06 |
Dolastatin 15 derivatives Grant 6,143,721 - Janssen , et al. November 7, 2 | 2000-11-07 |
Dolastatin 15 derivatives Grant 5,985,837 - Ritter , et al. November 16, 1 | 1999-11-16 |
Dolastatin 15 derivatives with carbonyl and heterocyclic functionalities at the C-terminus Grant 5,965,537 - Ritter , et al. October 12, 1 | 1999-10-12 |
Preparation of active peptides Grant 5,965,700 - Amberg , et al. October 12, 1 | 1999-10-12 |
Carboxylic acid derivatives, their preparation and use Grant 5,932,730 - Riechers , et al. August 3, 1 | 1999-08-03 |
Oligopeptides, the preparation and use thereof Grant 5,807,984 - Kling , et al. September 15, 1 | 1998-09-15 |