Patent | Date |
---|
Macrocyclic chlorine substituted indole derivatives Grant 11,447,504 - Thede , et al. September 20, 2 | 2022-09-20 |
Substituted macrocyclic indole derivatives Grant 11,440,923 - Thede , et al. September 13, 2 | 2022-09-13 |
Macrocyclic Fluorine Substituted Indole Derivatives App 20220281891 - Ferrara; Steven J. ;   et al. | 2022-09-08 |
Macrocyclic indole derivatives Grant 11,401,278 - Furst , et al. August 2, 2 | 2022-08-02 |
4H-pyrrolo[3,2-c]pyridin-4-one derivatives Grant 11,339,157 - Siegel , et al. May 24, 2 | 2022-05-24 |
Substituted dihydroimidazopyridinediones as MKNK1 and MKNK2 inhibitors Grant 11,311,520 - Klar , et al. April 26, 2 | 2022-04-26 |
Macrocyclic fluorine substituted indole derivatives Grant 11,286,263 - Ferrara , et al. March 29, 2 | 2022-03-29 |
Macrocyclic Indole Derivatives App 20210292341 - Furst; Laura ;   et al. | 2021-09-23 |
Macrocyclic Chlorine Substituted Indole Derivatives App 20210277022 - Thede; Kai ;   et al. | 2021-09-09 |
Substituted Macrocyclic Indole Derivatives App 20210269456 - Thede; Kai ;   et al. | 2021-09-02 |
Aryl Annulated Macrocyclic Indole Derivatives App 20210253598 - Thede; Kai ;   et al. | 2021-08-19 |
Macrocyclic indole derivatives Grant 10,981,932 - Johannes , et al. April 20, 2 | 2021-04-20 |
Substituted Dihydroimidazopyridinediones As Mknk1 And Mknk2 Inhibitors App 20210085656 - KLAR; Ulrich ;   et al. | 2021-03-25 |
Macrocyclic Fluorine Substituted Indole Derivatives App 20210079018 - Ferrara; Steven J. ;   et al. | 2021-03-18 |
Hetero-1,5,6,7-tetrahydro-4h-indol-4-ones App 20200216439 - GRAHAM; Keith ;   et al. | 2020-07-09 |
Macrocyclic Indole Derivatives App 20200087322 - Johannes; Sarah Anna Liesa ;   et al. | 2020-03-19 |
Substituted Imidazopyridinpyrimidines App 20190388425 - KLAR; Ulrich ;   et al. | 2019-12-26 |
Pyrazolopyridinamines as MKNK1 and MKNK2 inhibitors Grant 10,487,092 - Giese , et al. Nov | 2019-11-26 |
Substituted Dihydroimidazopyridinediones As Mknk1 And Mknk2 Inhibitors App 20190350910 - KLAR; Ulrich ;   et al. | 2019-11-21 |
3-amino-1,5,6,7-tetrahydro-4H-indol-4-ones Grant 10,428,044 - Graham , et al. October 1, 2 | 2019-10-01 |
4H-pyrrolo[3,2-C]pyridin-4-one derivatives Grant 10,428,063 - Graham , et al. October 1, 2 | 2019-10-01 |
1H-pyrrol-3-amines Grant 10,308,629 - Graham , et al. | 2019-06-04 |
3-amino-1,5,6,7-tetrahydro-4H-indol-4-ones Grant 10,227,299 - Graham , et al. | 2019-03-12 |
17-hydroxy-17-pentafluoroethyl-estra-4,9(10)-dien-11-aryl derivatives, method of production thereof and use thereof for the treatment of diseases Grant 10,155,004 - Schwede , et al. Dec | 2018-12-18 |
1h-pyrrol-3-amines App 20180222881 - GRAHAM; Keith ;   et al. | 2018-08-09 |
Pyrazolopyridinamines As Mknk1 And Mknk2 Inhibitors App 20180162877 - GIESE; Anja ;   et al. | 2018-06-14 |
3-amino-1,5,6,7-tetrahydro-4h-indol-4-ones App 20180155285 - GRAHAM; Keith ;   et al. | 2018-06-07 |
4h-pyrrolo[3,2-c]pyridin-4-one Derivatives App 20180016272 - GRAHAM; Keith ;   et al. | 2018-01-18 |
17-hydroxy-17-pentafluoroethyl-estra-4,9(10)-dien-11-aryl derivatives, method of production thereof and use thereof for the treatment of diseases Grant 9,717,739 - Schwede , et al. August 1, 2 | 2017-08-01 |
17-hydroxy-17-pentafluoroethyl-estra-4,9(10)-dien-11-aryl Derivatives, Method Of Production Thereof And Use Thereof For The Treatment Of Diseases App 20170202857 - SCHWEDE; Wolfgang ;   et al. | 2017-07-20 |
Benzothiadiazolamines App 20170197979 - GIESE; Anja ;   et al. | 2017-07-13 |
Substituted thiazolopyrimidines Grant 9,675,612 - Klar , et al. June 13, 2 | 2017-06-13 |
Substituted Tetrahydropyridothienopyrimidines App 20170107229 - KLAR; Ulrich ;   et al. | 2017-04-20 |
3-amino-1,5,6,7-tetrahydro-4h-indol-4-ones App 20170101391 - GRAHAM; Keith ;   et al. | 2017-04-13 |
Substituted pyrazolopyrimidinylamino-indazoles Grant 9,556,181 - Klar , et al. January 31, 2 | 2017-01-31 |
Thienopyrimidines Grant 9,540,392 - Kettschau , et al. January 10, 2 | 2017-01-10 |
Substituted imidazopyridazines Grant 9,512,126 - Koppitz , et al. December 6, 2 | 2016-12-06 |
Substituted imidazopyridazines Grant 9,512,130 - Koppitz , et al. December 6, 2 | 2016-12-06 |
Imidazopyrazines Grant 9,468,642 - Klar , et al. October 18, 2 | 2016-10-18 |
Thienopyrimidines As Mknk1 And Mknk2 Inhibitors App 20160297833 - KLAR; Ulrich ;   et al. | 2016-10-13 |
Substituted benzimidazoles Grant 9,388,140 - Klar , et al. July 12, 2 | 2016-07-12 |
Substituted pyrrolopyrimidinylamino-benzothiazolones as MKNK kinase inhibitors Grant 9,382,255 - Klar , et al. July 5, 2 | 2016-07-05 |
Substituted Pyrazolopyridines App 20160159789 - Klar; Ulrich ;   et al. | 2016-06-09 |
Substituted Thienopyrimidines And Pharmaceutical Use Thereof App 20160159816 - KETTSCHAU; Georg ;   et al. | 2016-06-09 |
Substituted benzothienopyrimidines Grant 9,296,757 - Klar , et al. March 29, 2 | 2016-03-29 |
Substituted imidazo[1,2-a]pyrazines as MPS-1 inhibitors Grant 9,284,317 - Koppitz , et al. March 15, 2 | 2016-03-15 |
Substituted imidazopyridazines Grant 9,255,100 - Klar , et al. February 9, 2 | 2016-02-09 |
Substituted Imidazopyridazines App 20160016959 - Koppitz; Marcus ;   et al. | 2016-01-21 |
Substituted Thiazolopyrimidines App 20160009734 - KLAR; Ulrich ;   et al. | 2016-01-14 |
Substituted Pyrazolopyrimidinylamino-indazoles App 20160002245 - KLAR; Ulrich ;   et al. | 2016-01-07 |
6-thio-substituted imidazo[1,2-a]pyrazines as Mps-1 inhibitors Grant 9,212,184 - Koppitz , et al. December 15, 2 | 2015-12-15 |
17-hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl derivatives, methods for the production thereof and the use thereof for treating diseases Grant 9,206,219 - Klar , et al. December 8, 2 | 2015-12-08 |
17-hydroxy-17-pentafluoroethyl-estra-4,9(10)-dien-11-aryl Derivatives, Method Of Production Thereof And Use Thereof For The Treatment Of Diseases App 20150342962 - SCHWEDE; Wolfgang ;   et al. | 2015-12-03 |
Substituted imidazopyrazines Grant 9,199,999 - Klar , et al. December 1, 2 | 2015-12-01 |
17-hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-benzylidene derivatives, methods for the production thereof and use thereof for treating diseases Grant 9,156,877 - Klar , et al. October 13, 2 | 2015-10-13 |
Substituted Indazol-pyrrolopyrimidines Useful In The Treatment Of Hyperproliferative Diseases App 20150252047 - Klar; Ulrich ;   et al. | 2015-09-10 |
Substituted Pyrrolopyrimidinylamino-benzothiazolones As Mknk Kinase Inhibitors App 20150239891 - Klar; Ulrich ;   et al. | 2015-08-27 |
Progesterone receptor antagonists Grant 9,109,004 - Schwede , et al. August 18, 2 | 2015-08-18 |
17-hydroxy-17-pentafluoroethyl-estra-4,9(10)-diene-11-ethynylphenyl derivatives, methods for the production thereof and use thereof for treating diseases Grant 9,102,701 - Klar , et al. August 11, 2 | 2015-08-11 |
Substituted Indazol-pyrrolopyrimidines Useful In The Treatment Of Hyperfoliferative Disorders App 20150218173 - Wortmann; Lars ;   et al. | 2015-08-06 |
17-hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-acyloxyalkylene phenyl derivatives, methods for the production thereof and use thereof for treating diseases Grant 9,096,639 - Klar , et al. August 4, 2 | 2015-08-04 |
17-hydroxy-17-pentafluoroethyl-estra-4,9(10)-diene-11-methylene oxyalkylene aryl derivatives, process for preparation thereof, and use thereof for treatment of diseases Grant 9,096,640 - Klar , et al. August 4, 2 | 2015-08-04 |
Progesterone receptor antagonists Grant 9,085,603 - Schwede , et al. July 21, 2 | 2015-07-21 |
Substituted Benzothienopyrimidines App 20150152121 - Klar; Ulrich ;   et al. | 2015-06-04 |
17-(1'propenyl)-17-3'-oxidoestra-4-en-3-one derivative, use thereof, and medicament containing said derivative Grant 9,034,856 - Klar , et al. May 19, 2 | 2015-05-19 |
Thienopyrimidines App 20150133425 - Kettschau; Georg ;   et al. | 2015-05-14 |
Substituted Pyrrolopyrimidines App 20150133426 - Klar; Ulrich ;   et al. | 2015-05-14 |
Substituted Imidazopyridazines App 20150104526 - Koppitz; Marcus ;   et al. | 2015-04-16 |
19-nor-steroid derivatives with a 15.alpha.,16.alpha.-methylene group and a saturated 17,17-spirolactone ring, use thereof, and medicaments containing said derivatives Grant 8,987,239 - Klar , et al. March 24, 2 | 2015-03-24 |
17-hydroxy-19-nor-21-carboxylic acid-steroid .gamma.-lactone derivative, use thereof, and medicament containing the derivative Grant 8,937,058 - Klar , et al. January 20, 2 | 2015-01-20 |
Substituted Benzimidazoles App 20140302010 - Klar; Ulrich ;   et al. | 2014-10-09 |
Substituted Imidazopyridines And Intermediates Thereof App 20140255392 - Koppitz; Marcus ;   et al. | 2014-09-11 |
6 Substituted Imidazopyrazines For Use As Mps-1 And Tkk Inhibitors In The Treatment Of Hyperproliferative Disorders App 20140187548 - Koppitz; Marcus ;   et al. | 2014-07-03 |
6-substituted Imidazopyrazines For Use As Mps-1 And Tkk Inhibitors In The Treatment Of Hyperproliferative Disorders App 20140135319 - Koppitz; Marcus ;   et al. | 2014-05-15 |
15, 16-methylene-17-(1'-propenyl)-17,3'-oxidoestra-4-en-3-one derivative, use thereof, and medicament containing said derivative Grant 8,623,850 - Klar , et al. January 7, 2 | 2014-01-07 |
Substituted Imidazopyridazines App 20130338133 - Klar; Ulrich ;   et al. | 2013-12-19 |
Imidazopyrazines For Use As Mps-1 And Tkk Inhibitors In The Treatment Hyperproliferative Disorders App 20130303532 - Koppitz; Marcus ;   et al. | 2013-11-14 |
6-thio-substituted Imidazopyrazines For Use As Mps-1 And Tkk Inhibitors In The Treatment Of Hyperproliferative Disorders App 20130281460 - Koppitz; Marcus ;   et al. | 2013-10-24 |
Substituted 6-imidazopyrazines For Use As Mps-1 And Tkk Inhibitors In The Treatment Of Hyperproliferative Disorders App 20130267527 - Koppitz; Marcus ;   et al. | 2013-10-10 |
Substituted Imidazopyrazines App 20130210815 - Klar; Ulrich ;   et al. | 2013-08-15 |
Imidazopyrazines App 20130195848 - Klar; Ulrich ;   et al. | 2013-08-01 |
19-NOR-STEROID DERIVATIVES WITH A 15a,16a-METHYLENE GROUP AND A SATURATED 17,17-SPIROLACTONE RING, USE THEREOF, AND MEDICAMENTS CONTAINING SAID DERIVATIVES App 20130123219 - KLAR; Ulrich ;   et al. | 2013-05-16 |
Progesterone Receptor Antagonists App 20130072464 - Schwede; Wolfgang ;   et al. | 2013-03-21 |
Progesterone Receptor Antagonists App 20130005697 - Schwede; Wolfgang ;   et al. | 2013-01-03 |
17-hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-benzylidene Derivatives, Methods For The Production Thereof And Use Thereof For Treating Diseases App 20120316145 - Klar; Ulrich ;   et al. | 2012-12-13 |
17-hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl Derivatives, Methods For The Production Thereof And The Use Thereof For Treating Diseases App 20120258941 - Klar; Ulrich ;   et al. | 2012-10-11 |
17-hydroxy-17-pentafluoroethyl-estra-4,9(10)-dien-11-aryl derivatives, method of production thereof and use thereof for the treatment of diseases Grant 8,278,469 - Schwede , et al. October 2, 2 | 2012-10-02 |
17-hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-acyloxyalkylene Phenyl Derivatives, Methods For The Production Thereof And Use Thereof For Treating Diseases App 20120232042 - Klar; Ulrich ;   et al. | 2012-09-13 |
17-hydroxy-17-pentafluoroethyl-estra-4,9(10)-diene-11-ethynylphenyl Derivatives, Methods For The Production Thereof And Use Thereof For Treating Diseases App 20120190660 - Klar; Ulrich ;   et al. | 2012-07-26 |
17-hydroxy-17-pentafluoroethyl-estra-4,9(10)-diene-11-methylene Oxyalkylene Aryl Derivatives, Process For Preparation Thereof, And Use Thereof For Treatment Of Diseases App 20120184515 - Klar; Ulrich ;   et al. | 2012-07-19 |
17.beta.-cyano-19-nor-androst-4-ene derivative, its use and medicaments comprising the derivative Grant 8,207,150 - Kuhnke , et al. June 26, 2 | 2012-06-26 |
17-hydroxy-17-pentafluoroethyl-estra-4,9(10)-dien-11-aryl Derivatives, Method Of Production Thereof And Use Thereof For The Treatment Of Diseases App 20120149670 - Schwede; Wolfgang ;   et al. | 2012-06-14 |
17-hydroxy-17-pentafluoroethyl-estra-4,9(10)-dien-11-aryl Derivatives, Method Of Production Thereof And Use Thereof For The Treatment Of Diseases App 20120094969 - SCHWEDE; Wolfgang ;   et al. | 2012-04-19 |
17-hydroxy-19-nor-21-carboxylic Acid-steroid Y-lactone Derivative, Use Thereof, And Medicament Containing The Derivative App 20110021472 - Klar; Ulrich ;   et al. | 2011-01-27 |
15,16-Methylene-17-hydroxy-19-nor-21-carboxylic acid-steroid Y-lactone derivative, use thereof and medicinal products containing the derivative App 20110015162 - Klar; Ulrich ;   et al. | 2011-01-20 |
15, 16-methylene-17-(1'-propenyl)-17,3'-oxidoestra-4-en-3-one Derivative , Use Thereof, And Medicament Containing Said Derivative App 20110003779 - Klar; Ulrich ;   et al. | 2011-01-06 |
17-(1'propenyl)-17-3'-oxidoestra-4-en-3-one Derivative, Use Thereof, And Medicament Containing Said Derivative App 20100317632 - Klar; Ulrich ;   et al. | 2010-12-16 |
19-nor-steroid Derivatives With A 15alpha, 16alpha-methylene Group And A Saturated 17, 17-spiro-lactone Ring, Use Thereof, And Medicaments Containing Said Derivatives App 20100311702 - Klar; Ulrich ;   et al. | 2010-12-09 |
17beta-cyano-19-androst-4-ene Derivative, Its Use And Medicaments Comprising The Derivative App 20100292184 - Kuhnke; Joachim ;   et al. | 2010-11-18 |
6-alkenyl-, 6-alkinyl- And 6-epoxy-epothilone Derivatives, Process For Their Production, And Their Use In Pharmaceutical Preparations App 20100168179 - Klar; Ulrich ;   et al. | 2010-07-01 |
6-alkenyl-, 6-alkinyl- and 6-epoxy-epothilone derivatives, process for their production, and their use in pharmaceutical preparations Grant 7,700,621 - Klar , et al. April 20, 2 | 2010-04-20 |
6-alkenyl-, 6-alkinyl- and 6-epoxy-epothilone derivatives, process for their production, and their use in pharmaceutical preparations Grant 7,645,891 - Klar , et al. January 12, 2 | 2010-01-12 |
Effector conjugates, methods for their preparation and their pharmaceutical use Grant 7,605,136 - Bosslet , et al. October 20, 2 | 2009-10-20 |
Combinations Comprising A Prostaglandin And Uses Thereof App 20090163450 - Hoffmann; Jens ;   et al. | 2009-06-25 |
17Beta-CYANO-19-NOR-ANDROST-4-ENE DERIVATIVE, ITS USE AND MEDICAMENTS COMPRISING THE DERIVATIVE App 20090048217 - KUHNKE; Joachim ;   et al. | 2009-02-19 |
17Beta-CYANO-18A-HOMO-19-NOR-ANDROST-4-ENE DERIVATIVE, ITS USE AND MEDICAMENTS COMPRISING THE DERIVATIVE App 20090048218 - KUHNKE; JOACHIM ;   et al. | 2009-02-19 |
Radiofluorination App 20090035215 - Srinivasan; Ananth ;   et al. | 2009-02-05 |
New Epothiolone Derivatives, Process For Their Production, And Their Pharmaceutical Use App 20090018342 - KLAR; Ulrich ;   et al. | 2009-01-15 |
Epothilone derivatives, method for producing same and their pharmaceutical use Grant 7,407,975 - Klar , et al. August 5, 2 | 2008-08-05 |
New effector conjugates, process for their production and their pharmaceutical use App 20080166362 - Berger; Markus ;   et al. | 2008-07-10 |
Use Of Epothilones In The Treatment Of Osteoporosis And Related Diseases App 20080146626 - Kaekoenen; Sanna ;   et al. | 2008-06-19 |
Effector conjugates, process for their production and their pharmaceutical use Grant 7,335,775 - Berger , et al. February 26, 2 | 2008-02-26 |
Method for producing c1-c15 fragments of epothilones and the derivatives thereof App 20070142675 - Klar; Ulrich ;   et al. | 2007-06-21 |
New effector conjugates, process for their production and their pharmaceutical use App 20070088060 - Berger; Markus ;   et al. | 2007-04-19 |
Antigestagenically active steroids with a fluorinated 17.alpha.-alkyl chain Grant 7,148,213 - Schwede , et al. December 12, 2 | 2006-12-12 |
New effector conjugates, methods for their preparation and their pharmaceutical use App 20060276413 - Bosslet; Klaus ;   et al. | 2006-12-07 |
Effector conjugates, process for their production and their pharmaceutical use Grant 7,129,254 - Berger , et al. October 31, 2 | 2006-10-31 |
6-alkenyl-, 6-alkinyl- and 6-epoxy-epothilone derivatives, process for their production, and their use in pharmaceutical preparations Grant 7,125,893 - Klar , et al. October 24, 2 | 2006-10-24 |
Antiestrogens, process for their production and their pharmaceutical use Grant 7,074,829 - Klar , et al. July 11, 2 | 2006-07-11 |
Use of Epothilones in the treatment of bone metastasis App 20060069136 - Klar; Ulrich ;   et al. | 2006-03-30 |
6-Alkenyl -, 6-alkinyl- and 6-epoxy-epothilone derivatives, process for their production, and their use in pharmaceutical preparations App 20060046997 - Klar; Ulrich ;   et al. | 2006-03-02 |
Epothilone derivatives, process for their production, and their pharmaceutical use App 20060040990 - Klar; Ulrich ;   et al. | 2006-02-23 |
Epothilon derivatives, method for the production and the use thereof as pharmaceuticals Grant 7,001,916 - Klar , et al. February 21, 2 | 2006-02-21 |
New effector conjugates, process for their production and their pharmaceutical use App 20050234247 - Klar, Ulrich ;   et al. | 2005-10-20 |
16-Halogen-epothilone derivatives, method for producing them and their pharmaceutical use App 20050187270 - Klar, Ulrich ;   et al. | 2005-08-25 |
16-halogen-epothilone derivatives, process for their production, and their pharmaceutical use Grant 6,930,102 - Klar , et al. August 16, 2 | 2005-08-16 |
6-Alkenyl-, 6-alkinyl- and 6-epoxy-epothilone derivatives, process for their production, and their use in pharmaceutical preparations App 20050113429 - Klar, Ulrich ;   et al. | 2005-05-26 |
Antigestagenically active steroids with a fluorinated 17alpha-alkyl chain App 20050080060 - Schwede, Wolfgang ;   et al. | 2005-04-14 |
New effector conjugates, process for their production and their pharmaceutical use App 20050026971 - Berger, Markus ;   et al. | 2005-02-03 |
Antigestagenically active steroids with a fluorinated 17-alpha-alkyl chain Grant 6,806,263 - Schwede , et al. October 19, 2 | 2004-10-19 |
Effector conjugates, methods for their preparation and their pharmaceutical use App 20040167083 - Bosslet, Klaus ;   et al. | 2004-08-26 |
Novel epothilone derivatives, method for the preparation thereof and their pharmaceutical use App 20040058969 - Buchmann, Bernd ;   et al. | 2004-03-25 |
Use of Epothilones in the treatment of brain diseases associated with proliferative processes App 20040019088 - Lichtner, Rosemarie ;   et al. | 2004-01-29 |
16-halogen-epothilone derivatives, process for their production, and their pharmaceutical use App 20040014978 - Klar, Ulrich ;   et al. | 2004-01-22 |
C1-C6-epothilone fragments and process for the production of C1-C6-fragments of epothilones and derivatives thereof App 20030176710 - Klar, Ulrich ;   et al. | 2003-09-18 |
New antiestrogens, process for their production and their pharmaceutical use App 20030162830 - Klar, Ulrich ;   et al. | 2003-08-28 |
16-Halogen-epothilone derivatives, method for producing them and their pharmaceutical use Grant 6,610,736 - Klar , et al. August 26, 2 | 2003-08-26 |
Epothilone Derivatives, Method For Producing Same And Their Pharmaceutical Use App 20030144523 - KLAR, ULRICH ;   et al. | 2003-07-31 |
9-oxa-epothilon derivatives, method for the production and use thereof in pharmaceutical preparations App 20030139460 - Schwede, Wolfgang ;   et al. | 2003-07-24 |
Steroid esters and amides, process for their production and their pharmaceutical use Grant 6,596,713 - Klar , et al. July 22, 2 | 2003-07-22 |
Antigestagenically active steroids with a fluorinated 17-alpha-alkyl chain App 20030134834 - Schwede, Wolfgang ;   et al. | 2003-07-17 |
Antigestagenically active steroids with a fluorinated 17-alpha-alkyl chain App 20020045774 - Schwede, Wolfgang ;   et al. | 2002-04-18 |
Antigestagenically active steroids with a flourinated 17 .alpha.-alkyl chain Grant 6,316,432 - Schwede , et al. November 13, 2 | 2001-11-13 |
Borneol derivatives, methods of manufacturing them, and their pharmaceutical use Grant 6,025,507 - Klar , et al. February 15, 2 | 2000-02-15 |