loadpatents
name:-0.033547163009644
name:-0.057646036148071
name:-0.0012490749359131
Keefer; Larry K. Patent Filings

Keefer; Larry K.

Patent Applications and Registrations

Patent applications and USPTO patent grants for Keefer; Larry K..The latest application filed is for "nitric oxide-releasing diazeniumdiolated polyvinylpyrrolidone-based polymers, and compositions, medical devices, and uses thereof".

Company Profile
0.55.24
  • Keefer; Larry K. - Bethesda MD
  • Keefer; Larry K - Bethesda MD
*profile and listings may contain filings by different individuals or companies with the same name. Review application materials to confirm ownership/assignment.
Patent Activity
PatentDate
Nitric oxide-releasing diazeniumdiolated polyvinylpyrrolidone-based polymers, and compositions, medical devices, and uses thereof
Grant 9,540,471 - Hrabie , et al. January 10, 2
2017-01-10
Diazeniumdiolated compounds, pharmaceutical compositions, and method of treating cancer
Grant 9,205,091 - Maciag , et al. December 8, 2
2015-12-08
Hybrid diazeniumdiolated compounds, pharmaceutical compositions, and method of treating cancer
Grant 9,168,266 - Maciag , et al. October 27, 2
2015-10-27
Nitric Oxide-releasing Diazeniumdiolated Polyvinylpyrrolidone-based Polymers, And Compositions, Medical Devices, And Uses Thereof
App 20150166706 - Hrabie; Joseph A. ;   et al.
2015-06-18
Hybrid Diazeniumdiolated Compounds, Pharmaceutical Compositions, And Method Of Treating Cancer
App 20140315865 - Maciag; Anna E. ;   et al.
2014-10-23
Nitroxyl (HNO) releasing compounds and uses thereof in treating diseases
Grant 8,633,177 - Miranda , et al. January 21, 2
2014-01-21
Nitroxyl (hno) Releasing Compounds And Uses Thereof In Treating Diseases
App 20130065863 - Miranda; Katrina M. ;   et al.
2013-03-14
Diazeniumdiolated Compounds, Pharmaceutical Compositions, And Method Of Treating Cancer
App 20120238518 - Maciag; Anna E. ;   et al.
2012-09-20
Nitric oxide-releasing diazeniumdiolated compounds
Grant 8,093,343 - Hrabie , et al. January 10, 2
2012-01-10
Nitric Oxide-releasing Diazeniumdiolated Compounds
App 20110282060 - Hrabie; Joseph A. ;   et al.
2011-11-17
Nitric oxide-releasing diazeniumdiolated acrylonitrile-based polymers, and compositions, medical devices, and uses thereof
Grant 7,968,664 - Hrabie , et al. June 28, 2
2011-06-28
Polysaccharide-derived nitric oxide-releasing carbon-bound diazeniumdiolates
Grant 7,928,079 - Hrabie , et al. April 19, 2
2011-04-19
Polydiazeniumdiolated cyclic polyamines with polyphasic nitric oxide release and related compounds, compositions comprising same and methods of using same
Grant 7,928,096 - Waterhouse , et al. April 19, 2
2011-04-19
Methods for separation and detection of ketosteroids and other carbonyl-containing compounds
Grant 7,807,472 - Xu , et al. October 5, 2
2010-10-05
Polydiazeniumdiolated Cyclic Polyamines With Polyphasic Nitric Oxide Release And Related Compounds, Compositions Comprising Same And Methods Of Using Same
App 20090068248 - Waterhouse; David J. ;   et al.
2009-03-12
Polydiazeniumdiolated cyclic polyamines with polyphasic nitric oxide release and related compounds, compositions comprising same and methods of using same
Grant 7,468,435 - Waterhouse , et al. December 23, 2
2008-12-23
Polysaccharide-Derived Nitric Oxide-Releasing Carbon-Bound Diazeniumdiolates
App 20080306012 - Hrabie; Joseph A. ;   et al.
2008-12-11
Nitric oxide-releasing medical devices
Grant 7,425,218 - Keefer , et al. September 16, 2
2008-09-16
Nitric oxide-releasing amidine diazeniumdiolates, compositions and uses thereof and method of making same
Grant 7,348,319 - Hrabie , et al. March 25, 2
2008-03-25
Nitric Oxide-Releasing Diazeniumdiolated Acrylonitrile-Based Polymers, and Compositions, Medical Devices, and Uses Thereof
App 20070292471 - Hrabie; Joseph A. ;   et al.
2007-12-20
Highly cross-linked, extremely hydrophobic nitric oxide-releasing polymers and methods for their manufacture and use
Grant 7,226,586 - Fitzhugh , et al. June 5, 2
2007-06-05
Analysis of large numbers of estrogens and other steroids and applications thereof
App 20070004045 - Xu; Xia ;   et al.
2007-01-04
Nitric oxide-releasing imidate and thioimidate diazeniumdiolates
Grant 7,105,502 - Arnold , et al. September 12, 2
2006-09-12
O.sup.2-substituted 1-[(2-carboxylato)pyrrolidin-1-yl]diazen-1-ium-1,2-diolates
Grant 7,081,524 - Saavedra , et al. July 25, 2
2006-07-25
Novel nitric oxide-releasing amidine diazeniumdiolates, compositions and uses thereof and method of making same
App 20050288260 - Hrabie, Joseph A. ;   et al.
2005-12-29
O2-substituted 1-[(2-carboxylato)pyrrolidin-1-yl]diazen-1-ium-1,2-diolates
App 20050214249 - Saavedra, Joseph E. ;   et al.
2005-09-29
Nitric oxide-releasing amidine diazeniumdiolates, compositions and uses thereof and method of making same
Grant 6,949,530 - Hrabie , et al. September 27, 2
2005-09-27
Methods for separation and detection of ketosteroids and other carbonyl-containing compounds
App 20050181514 - Xu, Xia ;   et al.
2005-08-18
Polydiazeniumdiolated cyclic polyamines with polyphasic nitric oxide release and related compounds, compositions comprising same and methods of using same
App 20050148566 - Waterhouse, David J. ;   et al.
2005-07-07
Nitric oxide-releasing amidine- and enamine-derived diazeniumdiolates, compositions and uses thereof and method of making same
Grant 6,911,478 - Hrabie , et al. June 28, 2
2005-06-28
O2-glycosylated 1-substituted diazen-1-ium-1,2-diolates
Grant 6,911,433 - Saavedra , et al. June 28, 2
2005-06-28
Nitric oxide-releasing metallic medical devices
Grant 6,887,485 - Fitzhugh , et al. May 3, 2
2005-05-03
Highly cross-linked, extremely hydrophobic nitric oxide-releasing polymers and methods for their manufacture and use
App 20050079148 - Fitzhugh, Anthony L. ;   et al.
2005-04-14
Novel, nitric oxide-releasing amidine- and enamine-derived diazeniumdiolates, compositions and uses thereof and method of making same
App 20040180863 - Hrabie, Joseph A. ;   et al.
2004-09-16
Nitric oxide-releasing amidine--and enamine-derived diazeniumdiolates, compositions and uses thereof and method of making same
Grant 6,750,254 - Hrabie , et al. June 15, 2
2004-06-15
Novel nitric oxide-releasing imidate and thioimidate diazeniumdiolates, compositions, uses thereof and method of making same
App 20040092484 - Arnold, Ernst V. ;   et al.
2004-05-13
Highly cross-linked, extremely hydrophobic nitric oxide-releasing polymers and methods for their manufacture and use
Grant 6,703,046 - Fitzhugh , et al. March 9, 2
2004-03-09
Novel nitric oxide-releasing amidine diazeniumdiolates, compositions and uses thereof and method of making same
App 20040014720 - Hrabie, Joseph A. ;   et al.
2004-01-22
Nitric oxide-releasing imidate and thioimidate diazeniumdiolates, compositions, uses thereof and method of making same
Grant 6,673,338 - Arnold , et al. January 6, 2
2004-01-06
Novel nitric oxide-releasing amidine- and enamine-derived diazeniumdiolates, compositions and uses thereof and method of making same
App 20030166619 - Hrabie, Joseph A. ;   et al.
2003-09-04
O2-arylated or O2-glycosylated 1-substituted diazen-1-ium-1,2-diolates and O2-substituted 1-[(2-carboxylato) pyrrolidin-1-yl] diazen-1-ium-1,2-diolates
Grant 6,610,660 - Saavedra , et al. August 26, 2
2003-08-26
O2-arylated or O2-glycosylated 1-substituted diazen-1-ium-1,2-diolates and O2-substituted 1-[(2-carboxylato) pyrrolidin-1-yl]diazen-1-ium-1,2-diolat- es
App 20030147845 - Saavedra, Joseph E. ;   et al.
2003-08-07
Highly cross-linked, extremely hydrophobic nitric oxide-releasing polymers and methods for their manufacture and use
App 20030077243 - Fitzhugh, Anthony L. ;   et al.
2003-04-24
Nitric oxide-releasing amidine- and enamine-derived diazeniumdiolates, compositions and uses thereof and method of making same
Grant 6,511,991 - Hrabie , et al. January 28, 2
2003-01-28
Nitric oxide-releasing medical devices
App 20020119115 - Keefer, Larry K. ;   et al.
2002-08-29
Nitric oxide-releasing 1-[(2-carboxylato)pyrrolidin-1-yl] diazen-1-ium-1,2-diolates and composition comprising same
Grant 6,379,660 - Saavedra , et al. April 30, 2
2002-04-30
Nitric oxide-releasing metallic medical devices
App 20010041184 - Fitzhugh, Anthony L. ;   et al.
2001-11-15
Novel nitric oxide-releasing amidine- and enamine-derived diazeniumdiolates, compositions and uses thereof and method of making same
App 20010025052 - Hrabie, Joseph A. ;   et al.
2001-09-27
Use of nitric oxide-releasing agents to treat impotency
Grant 6,290,981 - Keefer , et al. September 18, 2
2001-09-18
Nitric oxide-releasing metallic medical devices
Grant 6,270,779 - Fitzhugh , et al. August 7, 2
2001-08-07
Nitric oxide-releasing amidine- and enamine-derived diazeniumdiolates, compositions and uses thereof and method of making same
Grant 6,232,336 - Hrabie , et al. May 15, 2
2001-05-15
Biopolymer-bound nitric oxide-releasing compositions, pharmaceutical compositions incorporating same and methods of treating biological disorders using same
Grant 6,200,558 - Saavedra , et al. March 13, 2
2001-03-13
Polymer-bound nitric oxide/nucleophile adduct compositions, pharmaceutical compositions incorporating same and methods of treating biological disorders using same
Grant 6,110,453 - Keefer , et al. August 29, 2
2000-08-29
Use of nitric oxide-releasing agents to treat impotency
Grant 5,910,316 - Keefer , et al. June 8, 1
1999-06-08
Encapsulated and non-encapsulated nitric oxide generators used as antimicrobial agents
Grant 5,814,666 - Green , et al. September 29, 1
1998-09-29
Selective prevention of organ injury is sepsis and shock using selective release of nitric oxide vulnerable organs
Grant 5,814,656 - Saavedra , et al. September 29, 1
1998-09-29
Polymer-bound nitric oxide/nucleophile adduct compositions, pharmaceutical compositions incorporating same and methods of treating biological disorders using same
Grant 5,718,892 - Keefer , et al. February 17, 1
1998-02-17
Selective prevention of organ injury in sepsis and shock using selection release of nitric oxide in vulnerable organs
Grant 5,714,511 - Saavedra , et al. February 3, 1
1998-02-03
Use of nitric oxide-releasing agents for reducing metastasis risk
Grant 5,700,830 - Korthuis , et al. December 23, 1
1997-12-23
Polysaccharide-bound nitric oxide-nucleophile adducts
Grant 5,691,423 - Smith , et al. November 25, 1
1997-11-25
Method of generating nitric oxide gas using nitric oxide complexes
Grant 5,683,668 - Hrabie , et al. November 4, 1
1997-11-04
Implants, prostheses, and stents comprising polymer-bound nitric oxide/nucleophile adducts capable of releasing nitric oxide
Grant 5,676,963 - Keefer , et al. October 14, 1
1997-10-14
Nitric oxide-releasing polymers to treat restenosis and related disorders
Grant 5,650,447 - Keefer , et al. July 22, 1
1997-07-22
Biopolymer-bound nitric oxide-releasing compositions, pharmaceutical compositions incorporating same and methods of treating biological disorders using same
Grant 5,632,981 - Saavedra , et al. May 27, 1
1997-05-27
Polymer-bound nitric oxide/nucleophile adduct compositions, pharmaceutical compositions incorporating same and methods of treating biological disorders using same
Grant 5,525,357 - Keefer , et al. June 11, 1
1996-06-11
Polymer-bound nitric oxide/nucleophile adduct compositions, pharmaceutical compositions and methods of treating biological disorders
Grant 5,405,919 - Keefer , et al. April 11, 1
1995-04-11
Mixed ligand metal complexes of nitric oxide-nucleophile adducts useful as cardiovascular agents
Grant 5,389,675 - Christodoulou , et al. February 14, 1
1995-02-14
Oxygen substituted derivatives of nucleophile-nitric oxide adducts as nitric oxide donor prodrugs
Grant 5,366,997 - Keefer , et al. November 22, 1
1994-11-22
Complexes of nitric oxide with polyamines
Grant 5,250,550 - Keefer , et al. October 5, 1
1993-10-05
Antihypertensive compositions and use thereof
Grant 5,212,204 - Keefer , et al. May 18, 1
1993-05-18
Anti-hypertensive compositions of secondary amine-nitric oxide adducts and use thereof
Grant 5,208,233 - Keefer , et al. May 4, 1
1993-05-04
Therapeutic inhibition of platelet aggregation by nucleophile-nitric oxide complexes and derivatives thereof
Grant 5,185,376 - Diodati , et al. February 9, 1
1993-02-09
Complexes of nitric oxide with polyamines
Grant 5,155,137 - Keefer , et al. October 13, 1
1992-10-13
Anti-hypertensive compositions of secondary amine-nitric oxide adducts and use thereof
Grant 5,039,705 - Keefer , et al. August 13, 1
1991-08-13
Stabilized nitric oxide - primary amine complexes useful as cardiovascular agents
Grant 4,954,526 - Keefer September 4, 1
1990-09-04
Reductive destruction of nitrosamines, hydrazines, nitramines, azo- and azoxy-compounds
Grant 4,535,154 - Keefer , et al. August 13, 1
1985-08-13

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