Patent | Date |
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Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response Grant 10,066,230 - Kandimalla , et al. September 4, 2 | 2018-09-04 |
Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response Grant 10,041,076 - Kandimalla , et al. August 7, 2 | 2018-08-07 |
Immune Regulatory Oligonucleotide (iro) Compounds To Modulate Toll-like Receptor Based Immune Response App 20180023085 - Kandimalla; Ekambar R. ;   et al. | 2018-01-25 |
Immune Regulatory Oligonucleotide (iro) Compounds To Modulate Toll-like Receptor Based Immune Response App 20170233741 - Kandimalla; Ekambar R. ;   et al. | 2017-08-17 |
Immune Regulatory Oligonucleotide (iro) Compounds To Modulate Toll-like Receptor Based Immune Response App 20170145417 - Kandimalla; Ekambar R. ;   et al. | 2017-05-25 |
Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response Grant 9,540,651 - Kandimalla , et al. January 10, 2 | 2017-01-10 |
Immune Regulatory Oligonucleotide (iro) Compounds To Modulate Toll-like Receptor Based Immune Response App 20160312225 - Kandimalla; Ekambar R. ;   et al. | 2016-10-27 |
Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response Grant 9,453,228 - Kandimalla , et al. September 27, 2 | 2016-09-27 |
Immune Regulatory Oligonucleotide (iro) Compounds To Modulate Toll-like Receptor Based Immune Response App 20160215287 - Kandimalla; Ekambar R. ;   et al. | 2016-07-28 |
Immune Regulatory Oligonucleotide (iro) Compounds To Modulate Toll-like Receptor Based Immune Response App 20160138022 - Kandimalla; Ekambar R. ;   et al. | 2016-05-19 |
Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response Grant 9,260,719 - Kandimalla , et al. February 16, 2 | 2016-02-16 |
Stabilized immune modulatory RNA (SIMRA) compounds for TLR7 and TLR8 Grant 9,243,050 - Kandimalla , et al. January 26, 2 | 2016-01-26 |
Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response Grant 9,206,430 - Kandimalla , et al. December 8, 2 | 2015-12-08 |
Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response Grant 9,096,858 - Kandimalla , et al. August 4, 2 | 2015-08-04 |
Stabilized immunomodulatory oligonucleotides Grant 8,946,175 - Kandimalla , et al. February 3, 2 | 2015-02-03 |
Stabilized Immune Modulatory Rna (simra) Compounds For Tlr7 And Tlr8 App 20140308300 - Kandimalla; Ekambar R. ;   et al. | 2014-10-16 |
Immune Regulatory Oligonucleotide (iro) Compounds To Modulate Toll-like Receptor Based Immune Response App 20140193396 - Kandimalla; Ekambar R. ;   et al. | 2014-07-10 |
Stabilized immune modulatory RNA (SIMRA) compounds for TLR7 and TLR8 Grant 8,759,310 - Kandimalla , et al. June 24, 2 | 2014-06-24 |
Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes Grant 8,716,253 - Kandimalla , et al. May 6, 2 | 2014-05-06 |
Immune Regulatory Oligonucleotide (iro) Compounds To Modulate Toll-like Receptor Based Immune Response App 20140004100 - Kandimalla; Ekambar R. ;   et al. | 2014-01-02 |
Immune Regulatory Oligonucleotide (iro) Compounds To Modulate Toll-like Receptor Based Immune Response App 20130267583 - Kandimalla; Ekambar R. ;   et al. | 2013-10-10 |
Stabilized Immune Modulatory Rna (simra) Compounds For Tlr7 And Tlr8 App 20130202584 - Kandimalla; Ekambar R. ;   et al. | 2013-08-08 |
Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response Grant 8,486,908 - Kandimalla , et al. July 16, 2 | 2013-07-16 |
Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes Grant 8,476,416 - Kandimalla , et al. July 2, 2 | 2013-07-02 |
Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response Grant 8,377,898 - Kandimalla , et al. February 19, 2 | 2013-02-19 |
Synthetic agonists of TLR9 Grant 8,361,986 - Kandimalla , et al. January 29, 2 | 2013-01-29 |
Stabilized immune modulatory RNA (SIMRA) compounds Grant 8,362,233 - Kandimalla , et al. January 29, 2 | 2013-01-29 |
Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response Grant 8,357,665 - Kandimalla , et al. January 22, 2 | 2013-01-22 |
Modulation Of Immunostimulatory Properties Of Oligonucleotide-based Compounds By Utilizing Modified Immunostimulatory Dinucleotides App 20120201807 - Agrawal; Sudhir ;   et al. | 2012-08-09 |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5' ends Grant 8,202,850 - Agrawal , et al. June 19, 2 | 2012-06-19 |
Immune Regulatory Oligonucleotide (iro) Compounds To Modulate Toll-like Receptor Based Immune Response App 20120128699 - Kandimalla; Ekambar R. ;   et al. | 2012-05-24 |
Synergistic Treatment Of Cancer Using Immunomers In Conjunction With Chemotherapeutic Agents App 20120107303 - Kandimalla; Ekambar R. ;   et al. | 2012-05-03 |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by utilizing modified immunostimulatory dinucleotides Grant 8,153,608 - Agrawal , et al. April 10, 2 | 2012-04-10 |
Novel Agonists Of Toll-like Receptor 3 And Methods Of Their Use App 20120034248 - KANDIMALLA; EKAMBAR R. ;   et al. | 2012-02-09 |
Stabilized immune modulatory RNA (SIMRA) compounds for TLR7 and TLR8 Grant 8,106,173 - Kandimalla , et al. January 31, 2 | 2012-01-31 |
Novel Synthetic Agonists Of Tlr9 App 20110311518 - KANDIMALLA; EKAMBAR R. ;   et al. | 2011-12-22 |
Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes Grant 8,030,462 - Kandimalla , et al. October 4, 2 | 2011-10-04 |
Modulation Of Immunostimulatory Properties Of Oligonucleotide-based Compounds By Optimal Presentation Of 5' Ends App 20110229456 - AGRAWAL; SUDHIR ;   et al. | 2011-09-22 |
Stabilized immunomodulatory oligonucleotides Grant 8,008,267 - Kandimalla , et al. August 30, 2 | 2011-08-30 |
Modulation Of Immunostimulatory Properties Of Oligonucleotide-based Compounds By Utilizing Modified Immunostimulatory Dinucleotides App 20110150863 - Agrawal; Sudhir ;   et al. | 2011-06-23 |
Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes Grant 7,932,367 - Kandimalla , et al. April 26, 2 | 2011-04-26 |
Synergistic treatment of cancer using immunomers in conjunction with chemotherapeutic agents Grant 7,875,594 - Kandimalla , et al. January 25, 2 | 2011-01-25 |
Short immunomodulatory oligonucleotides Grant 7,851,454 - Agrawal , et al. December 14, 2 | 2010-12-14 |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by utilizing modified immunostimulatory dinucleotides Grant 7,851,453 - Agrawal , et al. December 14, 2 | 2010-12-14 |
Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes Grant 7,833,538 - Kandimalla , et al. November 16, 2 | 2010-11-16 |
Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes Grant 7,824,696 - Kandimalla , et al. November 2, 2 | 2010-11-02 |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5' ends Grant 7,812,000 - Agrawal , et al. October 12, 2 | 2010-10-12 |
Modulation of Immunostimulatory Properties of Oligonucleotide-Based Compounds by Optimal Presentation of 5' Ends App 20100254974 - Agrawal; Sudhir ;   et al. | 2010-10-07 |
Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes Grant 7,790,168 - Kandimalla , et al. September 7, 2 | 2010-09-07 |
Immunostimulatory activity of immune modulatory oligonucleotides (IMO.TM.) containing different lengths of palindromic segments Grant 7,786,089 - Kandimalla , et al. August 31, 2 | 2010-08-31 |
Immunostimulatory Activity Of Palindromic Immune Modulatory Oligonucleotides (imo) Containing Different Lengths Of Palindromic Segments App 20100215646 - Kandimalla; Ekambar R. ;   et al. | 2010-08-26 |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5' ends Grant 7,749,975 - Agrawal , et al. July 6, 2 | 2010-07-06 |
Immunostimulatory Properties Of Oligonucleotide-based Compounds Comprising Modified Immunostimulatory Dinucleotides App 20100143328 - Agrawal; Sudhir ;   et al. | 2010-06-10 |
Modulation of immunostimulatory properties by small oligonucleotide-based compounds Grant 7,713,535 - Agrawal , et al. May 11, 2 | 2010-05-11 |
Synergistic stimulation of the immune system using immunostimulatory oligonucleotides and/or immunomer compounds in conjunction with cytokines and/or chemotherapeutic agents or radiation therapy Grant 7,709,617 - Kandimalla , et al. May 4, 2 | 2010-05-04 |
Epidermal growth factor receptor antisense oligonucleotides Grant 7,671,035 - Agrawal , et al. March 2, 2 | 2010-03-02 |
Synergistic treatment of cancer using immunomers in conjunction with therapeutic agents Grant 7,569,554 - Kandimalla , et al. August 4, 2 | 2009-08-04 |
Immune Regulatory Oligonucleotide (iro) Compounds To Modulate Toll-like Receptor Based Immune Response App 20090098063 - Kandimalla; Ekambar R. ;   et al. | 2009-04-16 |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5' ends Grant 7,517,862 - Agrawal , et al. April 14, 2 | 2009-04-14 |
Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response App 20090060898 - Kandimalla; Ekambar R. ;   et al. | 2009-03-05 |
Novel Synthetic Agonists Of Tlr9 App 20090053206 - Kandimalla; Ekambar R. ;   et al. | 2009-02-26 |
Novel synthetic agonists of toll-like receptors containing CG dinucleotide modifications App 20080279785 - Kandimalla; Ekambar R. ;   et al. | 2008-11-13 |
Synergistic Treatment Of Cancer Using Immunomers In Conjunction With Chemotherapeutic Agents App 20080206265 - Kandimalla; Ekambar R. ;   et al. | 2008-08-28 |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5' ends Grant 7,407,944 - Agrawal , et al. August 5, 2 | 2008-08-05 |
Stabilized Immune Modulatory Rna (simra) Compounds For Tlr7 And Tlr8 App 20080171712 - Kandimalla; Ekambar R. ;   et al. | 2008-07-17 |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5' ends App 20080152662 - Agrawal; Sudhir ;   et al. | 2008-06-26 |
Immune Regulatory Oligonucleotide (iro) Compounds To Modulate Toll-like Receptor Based Immune Response App 20080089883 - Kandimalla; Ekambar R. ;   et al. | 2008-04-17 |
Short immunomodulatory oligonucleotides Grant 7,354,907 - Agrawal , et al. April 8, 2 | 2008-04-08 |
Modulation of immunostimulatory activity of immunostimulatory Oligonucleotide analogs by positional chemical changes App 20080027214 - Kandimalla; Ekambar R. ;   et al. | 2008-01-31 |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5' ends Grant 7,276,489 - Agrawal , et al. October 2, 2 | 2007-10-02 |
Immunostimulatory activity of immune modulatory oligonucleotides (IMOtm) containing different lengths of palindromic segments App 20070219153 - Kandimalla; Ekambar R. ;   et al. | 2007-09-20 |
Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes Grant 7,262,286 - Kandimalla , et al. August 28, 2 | 2007-08-28 |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5' ends App 20070173469 - Agrawal; Sudhir ;   et al. | 2007-07-26 |
Immunostimulatory properties of oligonucleotide-based compounds comprising modified immunostimulatory dinucleotides App 20070105800 - Agrawal; Sudhir ;   et al. | 2007-05-10 |
Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes App 20070072198 - Kandimalla; Ekambar R. ;   et al. | 2007-03-29 |
Modulation of oligonucleotide CpG-mediated immune stimulation by positional modification of nucleosides Grant 7,176,296 - Agrawal , et al. February 13, 2 | 2007-02-13 |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5' ends App 20060287262 - Agrawal; Sudhir ;   et al. | 2006-12-21 |
Synergisitic stimulation of the immune system using immunostimulatory oligonucleotides and/or immunomer compounds in conjunction with cytokines and/or chemotherapeutic agents or radiation therapy App 20060217328 - Kandimalla; Ekambar R. ;   et al. | 2006-09-28 |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by utilizing modified immunostimulatory dinucleotides App 20060211641 - Agrawal; Sudhir ;   et al. | 2006-09-21 |
Modulation of oligonucleotide CpG-mediated immune stimulation by positional modification of nucleosides Grant 7,105,495 - Agrawal , et al. September 12, 2 | 2006-09-12 |
Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes App 20060142224 - Kandimalla; Ekambar R. ;   et al. | 2006-06-29 |
Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes App 20060135454 - Kandimalla; Ekambar R. ;   et al. | 2006-06-22 |
Synergistic inhibition of VEGF and modulation of the immune response App 20060105979 - Agrawal; Sudhir ;   et al. | 2006-05-18 |
Synergistic stimulation of the immune system using immunostimulatory oligonucleotides and/or immunomer compounds in conjunction with cytokines and/or chemotherapeutic agents or radiation therapy App 20060074040 - Kandimalla; Ekambar R. ;   et al. | 2006-04-06 |
Sensitization of cells to cytotoxic agents using oligonucleotides directed to nucleotide excision repair or transcritpion coupled repair genes App 20060052319 - Agrawal; Sudhir ;   et al. | 2006-03-09 |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by utilizing modified immunostimulatory dinucleotides App 20060019918 - Agrawal; Sudhir ;   et al. | 2006-01-26 |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5' ends App 20060019909 - Agrawal; Sudhir ;   et al. | 2006-01-26 |
Modulation of immunostimulatory properties by small oligonucleotide-based compounds App 20050130918 - Agrawal, Sudhir ;   et al. | 2005-06-16 |
Hybridization-based fluorescence assay App 20050089915 - Kandimalla, Ekambar R. ;   et al. | 2005-04-28 |
Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes App 20050026858 - Kandimalla, Ekambar R. ;   et al. | 2005-02-03 |
Stabilized immunomodulatory oligonucleotides App 20050026861 - Kandimalla, Ekambar R. ;   et al. | 2005-02-03 |
Synergistic treatment of cancer using immunomers in conjunction with therapeutic agents App 20050009773 - Kandimalla, Ekambar R. ;   et al. | 2005-01-13 |
Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes App 20040266710 - Kandimalla, Ekambar R. ;   et al. | 2004-12-30 |
Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes App 20040266709 - Kandimalla, Ekambar R. ;   et al. | 2004-12-30 |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by utilizing modified immunostimulatory dinucleotides App 20040198685 - Agrawal, Sudhir ;   et al. | 2004-10-07 |
Short immunomodulatory oligonucleotides App 20040156825 - Agrawal, Sudhir ;   et al. | 2004-08-12 |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5' ends App 20040097719 - Agrawal, Sudhir ;   et al. | 2004-05-20 |
Modulation of oligonucleotide CpG-mediated immune stimulation by positional modification of nucleosides App 20030236211 - Agrawal, Sudhir ;   et al. | 2003-12-25 |
Sensitization of cells to cytotoxic agents using oligonucleotides directed to nucleotide excision repair or transcritpion coupled repair genes App 20030232767 - Agrawal, Sudhir ;   et al. | 2003-12-18 |
Antisense oligonucleotides and methods to induce tumor cell death App 20030125287 - Kandimalla, Ekambar R. ;   et al. | 2003-07-03 |
Cooperative oligonucleotides App 20030099959 - Kandimalla, Ekambar R. ;   et al. | 2003-05-29 |
Epidermal growth factor receptor antisense oligonucleotides App 20030045494 - Agrawal, Sudhir ;   et al. | 2003-03-06 |
Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes App 20020137714 - Kandimalla, Ekambar R. ;   et al. | 2002-09-26 |
Pseudo-cyclic oligonucleobases Grant 6,383,752 - Agrawal , et al. May 7, 2 | 2002-05-07 |
Cooperative oligonucleotides Grant 6,372,427 - Kandimalla , et al. April 16, 2 | 2002-04-16 |
Affinity-based purification of oligonucleotides using soluble multimeric oligonucleotides Grant 5,912,332 - Agrawal , et al. June 15, 1 | 1999-06-15 |
Mixed backbone antisense oligonucleotides containing 2'-5'-ribonucleotide- and 3'-5'-deoxyribonucleotides segments Grant 5,886,165 - Kandimalla , et al. March 23, 1 | 1999-03-23 |
Integrated oligonucleotides Grant 5,739,308 - Kandimalla , et al. April 14, 1 | 1998-04-14 |