Patent | Date |
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Spherical Nucleic Acid Tlr9 Agonists App 20220064649 - Anderson; Bart ;   et al. | 2022-03-03 |
Liposomal Spherical Nucleic Acid (sna) Constructs For Survival Of Motor Neuron (sma) Inhibitors App 20210002640 - Kang; Richard ;   et al. | 2021-01-07 |
Spherical Nucleic Acid Tlr9 Agonists App 20200255837 - Anderson; Bart ;   et al. | 2020-08-13 |
Tlr9-targeted Spherical Nucleic Acids Having Potent Antitumor Activity App 20200248183 - Kind Code | 2020-08-06 |
Synthesis Of Spherical Nucleic Acids Using Lipophilic Moieties App 20200188521 - Kang; Richard ;   et al. | 2020-06-18 |
Spherical Nucleic Acid Tlr9 Agonists App 20190225968 - Anderson; Bart ;   et al. | 2019-07-25 |
Immune Regulatory Oligonucleotide (iro) Compounds To Modulate Toll-like Receptor Based Immune Response App 20160201060 - Kandimalla; Ekambar ;   et al. | 2016-07-14 |
Potentiation of autoimmune and inflammatory disease treatments by immune regulatory oligonucleotide (IRO) antagonists of TLR7 and TLR9 Grant 8,987,221 - Zhu , et al. March 24, 2 | 2015-03-24 |
Compositions for Inhibiting Gene Expression and Uses Thereof App 20150044196 - Agrawal; Sudhir ;   et al. | 2015-02-12 |
Compositions for inhibiting gene expression and uses thereof Grant 8,877,722 - Agrawal , et al. November 4, 2 | 2014-11-04 |
Use of inhibitors of toll-like receptors in the prevention and treatment of hypercholesterolemia and hyperlipidemia and diseases related thereto Grant 8,853,177 - Zhu , et al. October 7, 2 | 2014-10-07 |
Toll like receptor modulators Grant 8,853,375 - Kandimalla , et al. October 7, 2 | 2014-10-07 |
Agonists of toll-like receptor 3 and methods of their use Grant 8,492,358 - Kandimalla , et al. July 23, 2 | 2013-07-23 |
Compositions For Inhibiting Gene Expression And Uses Thereof App 20130142778 - AGRAWAL; SUDHIR ;   et al. | 2013-06-06 |
Compositions for inhibiting gene expression and uses thereof Grant 8,431,544 - Agrawal , et al. April 30, 2 | 2013-04-30 |
Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response Grant 8,426,375 - Kandimalla , et al. April 23, 2 | 2013-04-23 |
Immunostimulatory oligonucleotide multimers Grant 8,420,615 - Agrawal , et al. April 16, 2 | 2013-04-16 |
Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response Grant 8,399,423 - Kandimalla , et al. March 19, 2 | 2013-03-19 |
Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response Grant 8,383,598 - Kandimalla , et al. February 26, 2 | 2013-02-26 |
Stabilized Immune Modulatory Rna (simra) Compounds App 20120183530 - Kandimalla; Ekambar ;   et al. | 2012-07-19 |
Synthetic RNA-based agonists of TLR7 Grant 8,202,974 - Lan , et al. June 19, 2 | 2012-06-19 |
Stabilized immune modulatory RNA (SIMRA) compounds Grant 8,188,261 - Kandimalla , et al. May 29, 2 | 2012-05-29 |
Modulation of toll-like receptor 5 expression by antisense oligonucleotides Grant 8,153,777 - Kandimalla , et al. April 10, 2 | 2012-04-10 |
Modulation of toll-like receptor 3 expression by antisense oligonucleotides Grant 8,153,605 - Kandimalla , et al. April 10, 2 | 2012-04-10 |
Compositions For Inhibiting Gene Expression And Uses Thereof App 20120016004 - AGRAWAL; SUDHIR ;   et al. | 2012-01-19 |
Immunostimulatory Properties Of Oligonucleotide-based Compounds Comprising Modified Immunostimulatory Dinucleotides App 20110305684 - Agrawal; Sudhir ;   et al. | 2011-12-15 |
Novel Synthetic Agonists Of Tlr9 App 20110293565 - Kandimalla; Ekambar ;   et al. | 2011-12-01 |
Potentiation of Autoimmune and Inflammatory Disease Treatments by Immune Regulatory Oligonucleotide (IRO) Antagonists of TLR7 and TLR9 App 20110171209 - Zhu; Fu-Gang ;   et al. | 2011-07-14 |
Synergistic Stimulation Of The Immune System Using Immunostimulatory Oligonucleotides And/or Immunomer Compounds In Conjunction With Cytokines And/or Chemotherapeutic Agents Or Radiation Therapy App 20110158937 - Kandimalla; Ekambar ;   et al. | 2011-06-30 |
Synthetic agonists of TLR9 Grant 7,960,362 - Kandimalla , et al. June 14, 2 | 2011-06-14 |
Synthetic Agonists Of Tlr9 App 20110135669 - KANDIMALLA; EKAMBAR ;   et al. | 2011-06-09 |
Potent Mucosal Immune Response Induced By Modified Immunomodulatory Oligonucleotides App 20110123540 - Wang; Daqing ;   et al. | 2011-05-26 |
Compositions For Inhibiting Gene Expression And Uses Thereof App 20110082186 - Agrawal; Sudhir ;   et al. | 2011-04-07 |
Synthetic agonists of TLR9 Grant 7,884,197 - Kandimalla , et al. February 8, 2 | 2011-02-08 |
Oligonucleotide-based Compounds As Inhibitors Of Toll-like Receptors App 20110009477 - Yu; Dong ;   et al. | 2011-01-13 |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by utilizing modified immunostimulatory dinucleotides Grant 7,863,250 - Agrawal , et al. January 4, 2 | 2011-01-04 |
Synthetic Rna-based Agonists Of Tlr7 App 20100215642 - Lan; Tao ;   et al. | 2010-08-26 |
Immunostimulatory properties of oligonucleotide-based compounds comprising modified immunostimulatory dinucleotides Grant 7,776,834 - Agrawal , et al. August 17, 2 | 2010-08-17 |
Modulation of immunostimulatory properties by small oligonucleotide-based compounds App 20100166805 - Agrawal; Sudhir ;   et al. | 2010-07-01 |
Immunostimulatory Oligonucleotide Multimers App 20100166736 - Agrawal; Sudhir ;   et al. | 2010-07-01 |
Modulation of Toll-Like Receptor 5 Expression by Antisense Oligonucleotides App 20100111937 - Kandimalla; Ekambar ;   et al. | 2010-05-06 |
Modulation of Toll-Like Receptor 2 Expression By Antisense Oligonucleotides App 20100111935 - Bhagat; Lakshmi ;   et al. | 2010-05-06 |
Modulation of Toll-Like Receptor 4 Expression by Antisense Oligonucleotides App 20100111936 - Putta; Mallikarjuna ;   et al. | 2010-05-06 |
Use of Inhibitors of Toll-Like Receptors in the Prevention and Treatment of Hypercholesterolemia and Hyperlipidemia and Diseases Related Thereto App 20100098685 - Zhu; Fu-Gang ;   et al. | 2010-04-22 |
Modulation Of Myeloid Differentation Primary Response Gene 88 (myd88) Expression By Antisense Oligonucleotides App 20100092486 - Kandimalla; Ekambar ;   et al. | 2010-04-15 |
Modulation Of Toll-like Receptor 8 Expression By Antisense Oligonucleotides App 20100047188 - Kandimalla; Ekambar ;   et al. | 2010-02-25 |
Modulation Of Toll-like Receptor 7 Expression By Antisense Oligonucleotides App 20100041734 - Kandimalla; Ekambar ;   et al. | 2010-02-18 |
Modulation Of Toll-like Receptor 3 Expression By Antisense Oligonucleotides App 20100041735 - Kandimalla; Ekambar ;   et al. | 2010-02-18 |
Modulation Of Toll-like Receptor 9 Expression By Antisense Oligonucleotides App 20100035967 - Kandimalla; Ekambar ;   et al. | 2010-02-11 |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by utilizing modified immunostimulatory dinucleotides Grant 7,632,822 - Agrawal , et al. December 15, 2 | 2009-12-15 |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by utilizing modified immunostimulatory dinucleotides Grant 7,595,305 - Agrawal , et al. September 29, 2 | 2009-09-29 |
Immunostimulatory oligonucleotide multimers Grant 7,566,702 - Agrawal , et al. July 28, 2 | 2009-07-28 |
Immune Regulatory Oligonucleotide (iro) Compounds To Modulate Toll-like Receptor Based Immune Response App 20090087388 - Kandimalla; Ekambar ;   et al. | 2009-04-02 |
Immune Regulatory Oligonucleotide (iro) Compounds To Modulate Toll-like Receptor Based Immune Response App 20090081198 - Kandimalla; Ekambar ;   et al. | 2009-03-26 |
Immunostimulatory oligonucleotide multimers Grant 7,498,425 - Agrawal , et al. March 3, 2 | 2009-03-03 |
Immunostimulatory oligonucleotide multimers Grant 7,498,426 - Agrawal , et al. March 3, 2 | 2009-03-03 |
Toll Like Receptor Modulators App 20090053148 - Kandimalla; Ekambar ;   et al. | 2009-02-26 |
Stabilized Immune Modulatory Rna (simra) Compounds App 20090053205 - Kandimalla; Ekambar ;   et al. | 2009-02-26 |
Short Immunomodulatory Oligonucleotides App 20090010938 - Agrawal; Sudhir ;   et al. | 2009-01-08 |
Immunostimulatory properties of oligonucleotide-based compounds comprising modified immunostimulatory dinucleotides Grant 7,470,674 - Agrawal , et al. December 30, 2 | 2008-12-30 |
Synthetic Agonists Of Tlr9 App 20080292648 - Kandimalla; Ekambar ;   et al. | 2008-11-27 |
Immunostimulatory oligonucleotide multimers Grant 7,427,405 - Agrawal , et al. September 23, 2 | 2008-09-23 |
Immunostimulatory Oligonucleotide Multimers App 20080193437 - Agrawal; Sudhir ;   et al. | 2008-08-14 |
Immunostimulatory oligonucleotide multimers Grant 7,405,285 - Agrawal , et al. July 29, 2 | 2008-07-29 |
Immunostimulatory oligonucleotide multimers App 20070179103 - Agrawal; Sudhir ;   et al. | 2007-08-02 |
Immunostimulatory properties of oligonucleotide-based compounds comprising modified immunostimulatory dinucleotides App 20070105801 - Agrawal; Sudhir ;   et al. | 2007-05-10 |
Short immunomodulatory oligonucleotides App 20070093439 - Agrawal; Sudhir ;   et al. | 2007-04-26 |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by utilizing modified immunostimulatory dinucleotides App 20060287261 - Agrawal; Sudhir ;   et al. | 2006-12-21 |
Modulation of oligonucleotide CpG-mediated immune stimulation by positional modification of nucleosides Grant 7,115,579 - Agrawal , et al. October 3, 2 | 2006-10-03 |
Immunostimulatory oligonucleotide multimers App 20060094681 - Agrawal; Sudhir ;   et al. | 2006-05-04 |
Immunostimulatory oligonucleotide multimers App 20060094680 - Agrawal; Sudhir ;   et al. | 2006-05-04 |
Immunostimulatory oligonucleotide multimers App 20060025365 - Agrawal; Sudhir ;   et al. | 2006-02-02 |
Immunostimulatory oligonucleotide multimers App 20060019919 - Agrawal; Sudhir ;   et al. | 2006-01-26 |
Immunostimulatory oligonucleotide multimers App 20060014713 - Agrawal; Sudhir ;   et al. | 2006-01-19 |
Enhanced activity of HIV vaccine using a second generation immunomodulatory oligonucleotide App 20050266015 - Clerici, Mario ;   et al. | 2005-12-01 |
Potent mucosal immune response induced by modified immunomodulatory oligonucleotides App 20050222072 - Wang, Daqing ;   et al. | 2005-10-06 |
Modulation of oligonucleotides CpG-mediated immune stimulation by positional modification of nucleosides App 20030212029 - Agrawal, Sudhir ;   et al. | 2003-11-13 |
Modulation of oligonucleotide CpG-mediated immune stimulation by positional modification of nucleosides App 20020132995 - Agrawal, Sudhir ;   et al. | 2002-09-19 |
Triplex-forming antisense oligonucleotides having abasic linkers targeting nucleic acids comprising mixed sequences of purines and pyrimidines Grant 5,693,773 - Kandimalla , et al. December 2, 1 | 1997-12-02 |