Holton; Robert A.
Patent Applications and Registrations
Patent applications and USPTO patent grants for Holton; Robert A..The latest application filed is for "processes for the production of polycyclic fused ring compounds".
Company Profile
0.75.61
- Holton; Robert A. - Tallahassee FL US
- Holton; Robert A. - Orlando FL
- Holton, Robert A. - Tallahasse FL
Patent Activity
| Patent | Date |
|---|---|
| Stereo controlled synthesis of (E,Z)-dienals via tandem Rh(I) catalyzed propargyl claisen rearrangement Grant 9,573,871 - Vidhani , et al. February 21, 2 | 2017-02-21 |
| Clamping assembly employing a shape memory alloy actuating apparatus Grant 8,522,930 - Preston , et al. September 3, 2 | 2013-09-03 |
| C(10) ethyl ester and C(10) cyclopropyl ester substituted taxanes Grant 8,242,166 - Vu , et al. August 14, 2 | 2012-08-14 |
| C10 cyclopentyl ester substituted taxanes Grant 8,003,812 - Holton , et al. August 23, 2 | 2011-08-23 |
| Processes For The Production Of Polycyclic Fused Ring Compounds App 20100228038 - Vu; Phong ; et al. | 2010-09-09 |
| C10 Cyclopentyl Ester Substituted Taxanes App 20100056614 - Holton; Robert A. ; et al. | 2010-03-04 |
| Processes for the production of polycyclic fused ring compounds Grant 7,667,055 - Vu , et al. February 23, 2 | 2010-02-23 |
| C(10) Ethyl Ester And C(10) Cyclopropyl Ester Substituted Taxanes App 20090318543 - Vu; Phong ; et al. | 2009-12-24 |
| C10 cyclopentyl ester substituted taxanes Grant 7,589,111 - Holton , et al. September 15, 2 | 2009-09-15 |
| Processes for the preparation of docetaxel Grant 7,550,608 - Vu , et al. June 23, 2 | 2009-06-23 |
| .beta.-lactam synthesis Grant 7,541,458 - Vu , et al. June 2, 2 | 2009-06-02 |
| Taxanes having a C10 ester substituent Grant 7,524,869 - Holton April 28, 2 | 2009-04-28 |
| Processes for the preparation of paclitaxel Grant 7,358,378 - Vu , et al. April 15, 2 | 2008-04-15 |
| Process for selective derivatization of taxanes Grant 7,288,665 - Holton , et al. October 30, 2 | 2007-10-30 |
| Taxanes Having C7 Hydroxy And C10 Heterosubstituted Acetate Substituents App 20070249707 - Holton; Robert A. | 2007-10-25 |
| C7 Ester And C10 Hydroxy Substituted Taxanes App 20070249708 - Holton; Robert A. | 2007-10-25 |
| Taxanes having a C10 carbonate substituent Grant 7,256,213 - Holton August 14, 2 | 2007-08-14 |
| C10 carbamoyloxy substituted taxane compositions Grant 7,230,013 - Holton , et al. June 12, 2 | 2007-06-12 |
| Taxanes having a C7 carbonate substituent Grant 7,226,944 - Holton June 5, 2 | 2007-06-05 |
| C7 ester substituted taxanes Grant 7,186,849 - Holton March 6, 2 | 2007-03-06 |
| Taxanes having a C7 heterosubstituted acetate substituent Grant 7,183,312 - Holton February 27, 2 | 2007-02-27 |
| C7 lactyloxy-substituted taxanes Grant 7,160,919 - Holton , et al. January 9, 2 | 2007-01-09 |
| C10 heterosubstituted acetate taxane compositions Grant 7,157,474 - Holton January 2, 2 | 2007-01-02 |
| Processes for the production of polycyclic fused ring compounds App 20060281934 - Vu; Phong ; et al. | 2006-12-14 |
| Processes for the preparation of paclitaxel App 20060281933 - Vu; Phong ; et al. | 2006-12-14 |
| Processes for the preparation of docetaxel App 20060281932 - Vu; Phong ; et al. | 2006-12-14 |
| Resolution of enantiomeric mixtures of beta-lactams App 20060281918 - Vu; Phong ; et al. | 2006-12-14 |
| Beta-lactam synthesis App 20060281914 - Vu; Phong ; et al. | 2006-12-14 |
| C10 cyclopropyl ester substituted taxane compositions App 20060189679 - Holton; Robert A. ; et al. | 2006-08-24 |
| Metal alkoxide taxane derivatives Grant 7,074,945 - Holton July 11, 2 | 2006-07-11 |
| Radiosensitizing taxanes and their pharmaceutical preparations Grant 7,067,552 - Holton , et al. June 27, 2 | 2006-06-27 |
| Enzymatic process for the resolution for enantiomeric mixtures of .beta.-lactams Grant 7,067,305 - Holton , et al. June 27, 2 | 2006-06-27 |
| C10 carbonate taxane compositions Grant 7,056,946 - Holton June 6, 2 | 2006-06-06 |
| Taxanes having a C10 carbonate substituent App 20060111401 - Holton; Robert A. | 2006-05-25 |
| 1-deoxy taxol analogs Grant 7,019,150 - Holton , et al. March 28, 2 | 2006-03-28 |
| C7 carbonate taxane compositions Grant 6,992,104 - Holton January 31, 2 | 2006-01-31 |
| Process for C7 silylation of hydroxy substituted taxanes and intermediates thereof App 20050272944 - Holton, Robert A. ; et al. | 2005-12-08 |
| C10 cyclopentyl ester substituted taxanes App 20050228037 - Holton, Robert A. ; et al. | 2005-10-13 |
| C7 lactyloxy-substituted taxanes App 20050209311 - Holton, Robert A. ; et al. | 2005-09-22 |
| C10 carbamoyloxy substituted taxane compositions App 20050182098 - Holton, Robert A. ; et al. | 2005-08-18 |
| Taxanes having a C7 carbonate substituent App 20050165051 - Holton, Robert A. | 2005-07-28 |
| C10 heterosubstituted acetate taxane compositions App 20050143447 - Holton, Robert A. | 2005-06-30 |
| C7 heterosubstituted acetate taxane compositions App 20050143446 - Holton, Robert A. | 2005-06-30 |
| Taxanes having a C10 carbamoyloxy substituent Grant 6,906,088 - Holton , et al. June 14, 2 | 2005-06-14 |
| Tetraalkylammonium alkoxides Grant 6,878,833 - Holton April 12, 2 | 2005-04-12 |
| 14-hydrido-9.beta.-hydroxytetracyclic taxanes Grant 6,878,834 - Holton , et al. April 12, 2 | 2005-04-12 |
| Butenyl substituted taxanes Grant 6,872,842 - Holton , et al. March 29, 2 | 2005-03-29 |
| Taxanes having a c10 Heterosubstituted acetate substituent Grant 6,872,837 - Holton March 29, 2 | 2005-03-29 |
| Tricyclic and tetracyclic taxane intermediates Grant 6,861,537 - Holton , et al. March 1, 2 | 2005-03-01 |
| C7 heterosubstituted acetate taxane compositions Grant 6,861,446 - Holton March 1, 2 | 2005-03-01 |
| C7 carbamoyloxy substituted taxane compositions App 20050020635 - Holton, Robert A. | 2005-01-27 |
| 14-Hydrido-9beta-hydroxytetracyclic taxanes App 20040192944 - Holton, Robert A. ; et al. | 2004-09-30 |
| C9 hydrido and acyloxy metal alkoxides Grant 6,797,833 - Holton , et al. September 28, 2 | 2004-09-28 |
| Taxanes having t-butoxycarbonyl substituted side-chains and pharmaceutical compositions containing them Grant 6,794,523 - Holton , et al. September 21, 2 | 2004-09-21 |
| C7 carbonate substituted taxanes Grant 6,780,879 - Holton August 24, 2 | 2004-08-24 |
| C7 carbonate taxane compositions App 20040138267 - Holton, Robert A. | 2004-07-15 |
| C7 acyloxy metal alkoxides Grant 6,762,309 - Holton , et al. July 13, 2 | 2004-07-13 |
| C10 carbonate taxane compositions App 20040122055 - Holton, Robert A. | 2004-06-24 |
| C7 carbamate substituted taxanes Grant 6,750,245 - Holton June 15, 2 | 2004-06-15 |
| Taxane formulations App 20040097579 - Holton, Robert A. | 2004-05-20 |
| C7 heterosubstituted acetate taxane compositions App 20040087547 - Holton, Robert A. | 2004-05-06 |
| Carbamoyl substituted .beta.-lactams Grant 6,730,782 - Holton , et al. May 4, 2 | 2004-05-04 |
| Process for the preparation of baccatin III analogs bearing new C2 and C4 functional groups Grant 6,727,369 - Holton , et al. April 27, 2 | 2004-04-27 |
| C10 ester substituted taxanes App 20040072872 - Holton, Robert A. | 2004-04-15 |
| Perparation of substituted isoserine esters using metal alkoxides and beta-lactams App 20040073048 - Holton, Robert A. | 2004-04-15 |
| Preparation of substituted isoserine esters using beta-lactams and metal or ammonium alkoxides App 20040073047 - Holton, Robert A. | 2004-04-15 |
| 9.beta.-hydroxytetracyclic taxanes Grant 6,710,191 - Holton , et al. March 23, 2 | 2004-03-23 |
| Process for selective derivatization of taxanes Grant 6,706,896 - Holton , et al. March 16, 2 | 2004-03-16 |
| C10 carbamoyloxy substituted taxanes App 20040034230 - Holton, Robert A. ; et al. | 2004-02-19 |
| 1- Deoxy baccatin III, 1-deoxy taxol and 1-deoxy taxol analogs and method for the preparation thereof App 20040029976 - Holton, Robert A. ; et al. | 2004-02-12 |
| C10 heterosubstituted acetate taxanes App 20040024051 - Holton, Robert A. | 2004-02-05 |
| Process for the preparation of metal alkoxides Grant 6,683,196 - Holton January 27, 2 | 2004-01-27 |
| C7 ester substituted taxanes App 20040014979 - Holton, Robert A. | 2004-01-22 |
| C7 heterosubstituted acetate taxanes Grant 6,673,833 - Holton January 6, 2 | 2004-01-06 |
| C10 heterosubstituted acetate taxanes Grant 6,664,275 - Holton December 16, 2 | 2003-12-16 |
| C10 carbonate substituted taxanes Grant 6,660,866 - Holton December 9, 2 | 2003-12-09 |
| Process for the preparation of ammonium alkoxides Grant 6,653,490 - Holton November 25, 2 | 2003-11-25 |
| C2 substituted taxanes Grant 6,649,777 - Holton , et al. November 18, 2 | 2003-11-18 |
| C10 ester substituted taxanes Grant 6,649,632 - Holton November 18, 2 | 2003-11-18 |
| Taxane formulations Grant 6,638,973 - Holton October 28, 2 | 2003-10-28 |
| Enzymatic process for the resolution of enantiomeric mixtures of beta-lactams App 20030190743 - Holton, Robert A. ; et al. | 2003-10-09 |
| Taxane synthesis method and intermediates Grant 6,630,609 - Holton , et al. October 7, 2 | 2003-10-07 |
| Beta-lactams having an alkyl-substituted side chain App 20030187061 - Holton, Robert A. ; et al. | 2003-10-02 |
| Method for the preparation of 1-deoxy baccatin III, 1-deoxy taxol and 1-deoxy taxol analogs Grant 6,620,950 - Holton , et al. September 16, 2 | 2003-09-16 |
| C7 ester substituted taxanes Grant 6,610,860 - Holton August 26, 2 | 2003-08-26 |
| C10 carbamoyloxy substituted taxanes Grant 6,596,737 - Holton , et al. July 22, 2 | 2003-07-22 |
| Process for the preparation of metal alkoxides App 20030120096 - Holton, Robert A. | 2003-06-26 |
| C9 hydrido, hydroxy and acyloxy metal alkoxides App 20030114419 - Holton, Robert A. ; et al. | 2003-06-19 |
| C10 carbonate substituted taxanes App 20030114493 - Holton, Robert A. | 2003-06-19 |
| Taxane synthesis method and intermediates App 20030097024 - Holton, Robert A. ; et al. | 2003-05-22 |
| Preparation of substituted isoserine esters using metal alkoxides and .beta.-lactams Grant 6,562,962 - Holton May 13, 2 | 2003-05-13 |
| Taxanes having T-butoxycarbonyl substituted side-chains and pharmaceutical compositions containing them App 20030065200 - Holton, Robert A. ; et al. | 2003-04-03 |
| C7 carbamate substituted taxanes App 20030060638 - Holton, Robert A. | 2003-03-27 |
| C7 Acyloxy Metal Alkoxides App 20030055272 - Holton, Robert A. ; et al. | 2003-03-20 |
| Tricyclic and tetracyclic taxane intermediates App 20030050485 - Holton, Robert A. ; et al. | 2003-03-13 |
| Butenyl substituted taxanes App 20030045531 - Holton, Robert A. ; et al. | 2003-03-06 |
| Method for the preparation of 1-deoxy baccatin III, 1-deoxy taxol and 1-deoxy taxol analogs App 20030028039 - Holton, Robert A. ; et al. | 2003-02-06 |
| 9beta-hydroxytetracyclic taxanes App 20030027855 - Holton, Robert A. ; et al. | 2003-02-06 |
| Process for the preparation of ammonium alkoxides App 20030009039 - Holton, Robert A. | 2003-01-09 |
| Taxanes having an alkyl substituted side-chain and pharmaceutical compositions containing them App 20020147335 - Holton, Robert A. ; et al. | 2002-10-10 |
| Carbamoyl substituted beta-lactams App 20020091274 - Holton, Robert A. ; et al. | 2002-07-11 |
| C10 carbamoyloxy substituted taxanes App 20020077341 - Holton, Robert A. ; et al. | 2002-06-20 |
| C10 heterosubstituted acetate taxanes App 20020068755 - Holton, Robert A. | 2002-06-06 |
| C7 carbonate substituted taxanes App 20020065304 - Holton, Robert A. | 2002-05-30 |
| C7 heterosubstituted acetate taxanes App 20020065305 - Holton, Robert A. | 2002-05-30 |
| C2 substituted taxanes App 20020058821 - Holton, Robert A. ; et al. | 2002-05-16 |
| Taxane formulations App 20020052403 - Holton, Robert A. | 2002-05-02 |
| Radiosensitizing taxanes and their pharmaceutical preparations App 20020040155 - Holton, Robert A. ; et al. | 2002-04-04 |
| C7 ester substituted taxanes App 20020013346 - Holton, Robert A. | 2002-01-31 |
| C7 Taxane Derivatives And Pharmaceutical Compositions Containing Them App 20020002292 - HOLTON, ROBERT A. ; et al. | 2002-01-03 |
| Tricyclic and tetracyclic taxane intermediates App 20010053857 - Holton, Robert A. ; et al. | 2001-12-20 |
| C10 ester substituted taxanes App 20010051639 - Holton, Robert A. | 2001-12-13 |
| C7 carbamoyloxy substituted taxanes App 20010051640 - Holton, Robert A. | 2001-12-13 |
| Preparation of substituted isoserine esters using metal alkoxides and beta-lactams App 20010014746 - Holton, Robert A. | 2001-08-16 |
| C9 taxane derivatives Grant 6,147,234 - Holton , et al. November 14, 2 | 2000-11-14 |
| Tricyclic taxanes having an alkoxy, alkenoxy or aryloxy substituted side-chain and pharmaceutical compositions containing them Grant 6,018,073 - Holton , et al. January 25, 2 | 2000-01-25 |
| C10 tricyclic taxanes Grant 5,998,656 - Holton , et al. December 7, 1 | 1999-12-07 |
| Taxanes having an alkoxy, alkenoxy or aryloxy substituted side-chain and pharmaceutical compositions containing them Grant 5,739,362 - Holton , et al. April 14, 1 | 1998-04-14 |
| C2 taxane derivaties and pharmaceutical compositions containing them Grant 5,728,725 - Holton , et al. March 17, 1 | 1998-03-17 |
| Metal alkoxide compounds Grant 5,723,634 - Holton March 3, 1 | 1998-03-03 |
| Taxanes having a pyridyl substituted side-chain and pharmaceutical compositions containing them Grant 5,489,601 - Holton , et al. February 6, 1 | 1996-02-06 |
| Synthetic process for the preparation of taxol and other tricyclic and tetracyclic taxanes Grant 5,405,972 - Holton , et al. April 11, 1 | 1995-04-11 |
| Process for the preparation of baccatin III analogs bearing new C2 and C4 functional groups Grant 5,399,726 - Holton , et al. March 21, 1 | 1995-03-21 |
| 10-desacetoxytaxol derivatives Grant 5,350,866 - Holton , et al. * September 27, 1 | 1994-09-27 |
| Butenyl substituted taxanes and pharmaceutical compositions containing them Grant 5,284,864 - Holton , et al. February 8, 1 | 1994-02-08 |
| Furyl or thienyl carbonyl substituted taxanes and pharmaceutical compositions containing them Grant 5,283,253 - Holton , et al. February 1, 1 | 1994-02-01 |
| Metal alkoxides Grant 5,274,124 - Holton December 28, 1 | 1993-12-28 |
| Certain substituted taxanes and pharmaceutical compositions containing them Grant 5,250,683 - Holton , et al. October 5, 1 | 1993-10-05 |
| Certain alkoxy substituted taxanes and pharmaceutical compositions containing them Grant 5,243,045 - Holton , et al. September 7, 1 | 1993-09-07 |
| Metal alkoxides Grant 5,229,526 - Holton July 20, 1 | 1993-07-20 |
| Furyl and thienyl substituted taxanes and pharmaceutical compositions containing them Grant 5,227,400 - Holton , et al. July 13, 1 | 1993-07-13 |
| Method for preparation of taxol using .beta.-lactam Grant 5,175,315 - Holton December 29, 1 | 1992-12-29 |
| Method for preparation of taxol using an oxazinone Grant 5,136,060 - Holton August 4, 1 | 1992-08-04 |
| Method for preparation of taxol using an oxazinone Grant 5,015,744 - Holton May 14, 1 | 1991-05-14 |
| Taxols, their preparation and intermediates thereof Grant 4,876,399 - Holton , et al. October 24, 1 | 1989-10-24 |
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