Holmes; Michael C.

Patent Applications and Registrations

Patent applications and USPTO patent grants for Holmes; Michael C..The latest application filed is for "method of inactivating a glucocorticoid receptor gene in an isolated cell".

Company Profile

17.77.81

Holmes; Michael C. - Richmond CA
Holmes; Michael C. - Brisbane CA
Holmes; Michael C. - Oakland CA
Holmes; Michael C - Richmond CA

*profile and listings may contain filings by different individuals or companies with the same name. Review application materials to confirm ownership/assignment.

Patent Activity

Patent	Date
Targeted disruption of T cell receptor genes using engineered zinc finger protein nucleases Grant 11,439,666 - Bonini , et al. September 13, 2	2022-09-13
Methods and compositions for targeted cleavage and recombination Grant 11,311,574 - Holmes , et al. April 26, 2	2022-04-26
Methods and compositions for modulating PD1 Grant 11,235,026 - Gregory , et al. February 1, 2	2022-02-01
T cell modifying compounds and uses thereof Grant 11,236,175 - Gregory , et al. February 1, 2	2022-02-01
Method Of Inactivating A Glucocorticoid Receptor Gene In An Isolated Cell App 20210102222 - Reik; Andreas ; et al.	2021-04-08
Methods And Compositions For Modification Of A Hla Locus App 20210054046 - Collingwood; Trevor ; et al.	2021-02-25
Targeted disruption of T cell receptor genes using engineered zinc finger protein nucleases Grant 10,918,668 - Gregory , et al. February 16, 2	2021-02-16
Isolated human cell with an inactivated glucocorticoid receptor gene Grant 10,907,175 - Reik , et al. February 2, 2	2021-02-02
Methods And Compositions For Producing Hepatocytes App 20210024885 - Yi; Fei ; et al.	2021-01-28
Methods and compositions for modification of a HLA locus Grant 10,858,416 - Collingwood , et al. December 8, 2	2020-12-08
Methods And Compositions For Targeted Cleavage And Recombination App 20200297762 - Holmes; Michael C. ; et al.	2020-09-24
Methods And Compositions For Engineering Immunity App 20200282079 - Holmes; Michael C. ; et al.	2020-09-10
Methods and compositions for increased transgene expression Grant 10,717,993 - Holmes , et al.	2020-07-21
Methods and compositions for targeted cleavage and recombination Grant 10,675,302 - Holmes , et al.	2020-06-09
Methods and compositions for engineering immunity Grant 10,639,383 - Holmes , et al.	2020-05-05
Delivery methods and compositions for nuclease-mediated genome engineering Grant 10,604,771 - Cannon , et al.	2020-03-31
Delivery methods and compositions for nuclease-mediated genome engineering Grant 10,494,648 - Holmes , et al. De	2019-12-03
Methods And Compositions For Nuclease-mediated Targeted Integration App 20190352671 - Holmes; Michael C. ; et al.	2019-11-21
B-cell Engineering App 20190352614 - Amora; Rainier ; et al.	2019-11-21
Method of treating factor IX deficiency using nuclease-mediated targeted integration Grant 10,370,680 - Holmes , et al.	2019-08-06
Methods And Compositions For The Treatment Of Rare Diseases App 20190167815 - Holmes; Michael C. ; et al.	2019-06-06
Targeted Disruption Of T Cell Receptor Genes Using Engineered Zinc Finger Protein Nucleases App 20190046579 - Bonini; Maria Chiara ; et al.	2019-02-14
Targeted disruption of T cell receptor genes using engineered zinc finger protein nucleases Grant 10,155,011 - Bonini , et al. Dec	2018-12-18
Methods And Compositions For Modulating Pd1 App 20180326000 - Gregory; Philip D. ; et al.	2018-11-15
Methods And Compositions For Modification Of A Hla Locus App 20180319864 - Collingwood; Trevor ; et al.	2018-11-08
Delivery methods and compositions for nuclease-mediated genome engineering in hematopoietic stem cells Grant 10,117,899 - Genovese , et al. November 6, 2	2018-11-06
Methods And Compositions For Gene Inactivation App 20180312826 - Ando; Dale ; et al.	2018-11-01
Methods and compositions for modification of a HLA locus Grant 10,072,062 - Collingwood , et al. September 11, 2	2018-09-11
Methods and compositions for modulating PD1 Grant 10,046,028 - Gregory , et al. August 14, 2	2018-08-14
Methods And Compositions For Treatment Of A Genetic Condition App 20180223311 - Cost; Gregory J. ; et al.	2018-08-09
Targeted Disruption Of T Cell Receptor Genes Using Engineered Zinc Finger Protein Nucleases App 20180214485 - Gregory; Philip D. ; et al.	2018-08-02
Delivery Methods And Compositions For Nuclease-mediated Genome Engineering App 20180216136 - Holmes; Michael C. ; et al.	2018-08-02
Delivery Of Target Specific Nucleases App 20180185516 - Ansell; Steven M. ; et al.	2018-07-05
Methods and compositions for treatment of a genetic condition Grant 9,963,715 - Cost , et al. May 8, 2	2018-05-08
Delivery methods and compositions for nuclease-mediated genome engineering Grant 9,957,526 - Holmes , et al. May 1, 2	2018-05-01
Targeted disruption of T cell receptor genes using talens Grant 9,937,207 - Gregory , et al. April 10, 2	2018-04-10
Targeted integration into stem cells Grant 9,834,787 - Gregory , et al. December 5, 2	2017-12-05
Gene correction of SCID-related genes in hematopoietic stem and progenitor cells Grant 9,833,479 - Conway , et al. December 5, 2	2017-12-05
Methods And Compositions For Targeted Cleavage And Recombination App 20170326174 - Holmes; Michael C. ; et al.	2017-11-16
Methods and compositions for targeted cleavage and recombination Grant 9,782,437 - Holmes , et al. October 10, 2	2017-10-10
Linear donor constructs for targeted integration Grant 9,765,360 - DeKelver , et al. September 19, 2	2017-09-19
Methods and compostions for targeted genomic deletion Grant 9,752,140 - Urnov , et al. September 5, 2	2017-09-05
Modification of CXCR4 using engineered zinc finger proteins Grant 9,717,759 - Holmes , et al. August 1, 2	2017-08-01
Methods And Compositions For Engineering Immunity App 20170196992 - Holmes; Michael C. ; et al.	2017-07-13
Gene Correction Of Scid-related Genes In Hematopoietic Stem And Progenitor Cells App 20170189450 - Conway; Anthony ; et al.	2017-07-06
T Cell Modifying Compounds And Uses Thereof App 20170183420 - Gregory; Philip D. ; et al.	2017-06-29
Methods and compositions for treatment of a genetic condition Grant 9,650,648 - Cost , et al. May 16, 2	2017-05-16
Methods and compositions for treating hemophilia B Grant 9,629,930 - Gregory , et al. April 25, 2	2017-04-25
Gene correction of SCID-related genes in hematopoietic stem and progenitor cells Grant 9,616,090 - Conway , et al. April 11, 2	2017-04-11
T cell modifying compounds and uses thereof Grant 9,597,357 - Gregory , et al. March 21, 2	2017-03-21
Methods and compositions for prevention or treatment of a disease Grant 9,574,211 - Gregory , et al. February 21, 2	2017-02-21
Methods and compositions for inhibiting viral entry into cells Grant 9,566,352 - Holmes , et al. February 14, 2	2017-02-14
Genome editing of a Rosa locus using nucleases Grant 9,567,573 - Gregory , et al. February 14, 2	2017-02-14
Methods And Compositions For Gene Inactivation App 20160326505 - Ando; Dale ; et al.	2016-11-10
Methods and compositions for gene inactivation Grant 9,434,776 - Ando , et al. September 6, 2	2016-09-06
Linear Donor Constructs For Targeted Integration App 20160237457 - DeKelver; Russell ; et al.	2016-08-18
Methods And Compositions For Modulating Pd1 App 20160220634 - Gregory; Philip D. ; et al.	2016-08-04
Methods and compositions for modulating PD1 Grant 9,402,879 - Gregory , et al. August 2, 2	2016-08-02
Methods And Compositions For Increased Transgene Expression App 20160215298 - Holmes; Michael C. ; et al.	2016-07-28
Linear donor constructs for targeted integration Grant 9,376,685 - DeKelver , et al. June 28, 2	2016-06-28
Methods and compositions for targeted cleavage and recombination Grant 9,289,451 - Urnov , et al. March 22, 2	2016-03-22
Method Of Inactivating A Glucocorticoid Receptor Gene In An Isolated Cell App 20160076056 - Reik; Andreas ; et al.	2016-03-17
Targeted integration and expression on exogenous nucleic acid sequences Grant 9,260,726 - Gregory , et al. February 16, 2	2016-02-16
Gene Correction Of Scid-related Genes In Hematopoietic Stem And Progenitor Cells App 20160030477 - Conway; Anthony ; et al.	2016-02-04
Methods And Compositions For Treating Hemophilia B App 20160022838 - Gregory; Philip D. ; et al.	2016-01-28
Methods and compositions for modification of the HPRT locus Grant 9,222,105 - Cost , et al. December 29, 2	2015-12-29
Method of inactivating a glucocorticoid receptor gene in an isolated cell Grant 9,217,026 - Reik , et al. December 22, 2	2015-12-22
Methods And Compositions For Prevention Or Treatment Of A Disease App 20150329875 - Gregory; Philip D. ; et al.	2015-11-19
Methods and compositions for treating hemophilia B Grant 9,175,280 - Gregory , et al. November 3, 2	2015-11-03
Methods and compositions for alteration of a cystic fibrosis transmembrane conductance regulator (CFTR) gene Grant 9,161,995 - Guschin , et al. October 20, 2	2015-10-20
Methods And Compositions For Regulating Hiv Infection App 20150267223 - Holmes; Michael C. ; et al.	2015-09-24
Methods And Compositions For Modification Of A Hla Locus App 20150252094 - Collingwood; Trevor ; et al.	2015-09-10
Rapid screening of biologically active nucleases and isolation of nuclease-modified cells Grant 9,121,072 - Holmes , et al. September 1, 2	2015-09-01
Methods And Compositions For Nuclease-mediated Targeted Integration App 20150240263 - Holmes; Michael C. ; et al.	2015-08-27
Rapid screening of biologically active nucleases and isolation of nuclease-modified cells Grant 9,115,409 - Doyon , et al. August 25, 2	2015-08-25
Linear Donor Constructs For Targeted Integration App 20150225727 - DeKelver; Russell ; et al.	2015-08-13
Delivery Methods And Compositions For Nuclease-mediated Genome Engineering In Hematopoietic Stem Cells App 20150174169 - Genovese; Pietro ; et al.	2015-06-25
Targeted Disruption Of T Cell Receptor Genes Using Engineered Zinc Finger Protein Nucleases App 20150164954 - Bonini; Maria Chiara ; et al.	2015-06-18
Linear donor constructs for targeted integration Grant 9,045,763 - DeKelver , et al. June 2, 2	2015-06-02
Delivery Methods And Compositions For Nuclease-mediated Genome Engineering App 20150110762 - Holmes; Michael C. ; et al.	2015-04-23
Modification Of Cxcr4 Using Engineered Zinc Finger Proteins App 20150110757 - Holmes; Michael C. ; et al.	2015-04-23
Targeted disruption of T cell receptor genes using engineered zinc finger protein nucleases Grant 8,956,828 - Bonini , et al. February 17, 2	2015-02-17
Methods and compositions for modification of a HLA locus Grant 8,945,868 - Collingwood , et al. February 3, 2	2015-02-03
Methods and compositions for targeted integration Grant 8,936,936 - Holmes , et al. January 20, 2	2015-01-20
Methods And Compositions For Targeted Cleavage And Recombination App 20140369980 - Holmes; Michael C. ; et al.	2014-12-18
Methods and compositions for modification of the HPRT locus Grant 8,895,264 - Cost , et al. November 25, 2	2014-11-25
Delivery Methods And Compositions For Nuclease-mediated Genome Engineering App 20140335063 - Cannon; Paula M. ; et al.	2014-11-13
Modification of CXCR4 using engineered zinc finger proteins Grant 8,871,905 - Holmes , et al. October 28, 2	2014-10-28
Targeted Disruption Of T Cell Receptor Genes Using Engineered Zinc Finger Protein Nucleases App 20140301990 - Gregory; Philip D. ; et al.	2014-10-09
Methods And Compositions For Increased Transgene Expression App 20140205576 - Holmes; Michael C. ; et al.	2014-07-24
Methods And Compositions For Alteration Of A Cystic Fibrosis Transmembrane Conductance Regulator (cftr) Gene App 20140205579 - Davis; Brian R. ; et al.	2014-07-24
Genome editing of a Rosa locus using zinc-finger nucleases Grant 8,771,985 - Cui , et al. July 8, 2	2014-07-08
Methods And Compositions For Muscular Dystrophies App 20140140969 - Beausejour; Christian ; et al.	2014-05-22
Methods And Compositions For Gene Inactivation App 20140127811 - Ando; Dale ; et al.	2014-05-08
T Cell Modifying Compounds And Uses Thereof App 20140120622 - Gregory; Philip D. ; et al.	2014-05-01
Methods And Compositions For Treatment Of A Genetic Condition App 20140093913 - Cost; Gregory J. ; et al.	2014-04-03
Methods And Compositions For Targeted Cleavage And Recombination App 20140086885 - Urnov; Fyodor ; et al.	2014-03-27
Methods And Compositions For Treatment Of A Genetic Condition App 20140080216 - Cost; Gregory J. ; et al.	2014-03-20
Methods And Compositions For Modulating Pd1 App 20140030240 - Gregory; Philip D. ; et al.	2014-01-30
Methods and compositions for gene inactivation Grant 8,569,253 - Ando , et al. October 29, 2	2013-10-29
Methods and compositions for modulating PD1 Grant 8,563,314 - Gregory , et al. October 22, 2	2013-10-22
Taregted Integration And Expression Of Exogenous Nucleic Acid Sequences App 20130244332 - Gregory; Philip D. ; et al.	2013-09-19
Methods and compositions for targeted cleavage and recombination Grant 8,524,500 - Urnov , et al. September 3, 2	2013-09-03
Methods and compositions for gene inactivation Grant 8,524,221 - Ando , et al. September 3, 2	2013-09-03
Rapid Screening Of Biologically Active Nucleases And Isolation Of Nuclease-modified Cells App 20130171657 - Doyon; Yannick ; et al.	2013-07-04
Methods And Compositions For Regulating Hiv Infection App 20130171732 - Holmes; Michael C. ; et al.	2013-07-04
Methods And Compositions For Alteration Of A Cystic Fibrosis Transmembrane Conductance Regulator (cftr) Gene App 20130145485 - Davis; Brian R. ; et al.	2013-06-06
Methods And Compositions For Modification Of The Hprt Locus App 20130137104 - Cost; Gregory J. ; et al.	2013-05-30
Methods And Compositions For Modification Of The Hprt Locus App 20130122591 - Cost; Gregory J. ; et al.	2013-05-16
Targeted deletion of cellular DNA sequences Grant 8,409,861 - Guschin , et al. April 2, 2	2013-04-02
Methods And Compositions For Gene Inactivation App 20120309091 - Ando; Dale ; et al.	2012-12-06
Methods and Compositions for Gene Inactivation App 20120308528 - Ando; Dale ; et al.	2012-12-06
Rapid Screening Of Biologically Active Nucleases And Isolation Of Nuclease-modified Cells App 20120237926 - Holmes; Michael C. ; et al.	2012-09-20
Methods And Compositions For Treating Hemophilia B App 20120128635 - GREGORY; Philip D. ; et al.	2012-05-24
Methods And Compositions For Inhibiting Viral Entry Into Cells App 20120093787 - HOLMES; Michael C. ; et al.	2012-04-19
Methods And Compositions For Modification Of A Hla Locus App 20120060230 - Collingwood; Trevor ; et al.	2012-03-08
Genome editing of a Rosa locus using zinc-finger nucleases App 20120017290 - Cui; Xiaoxia ; et al.	2012-01-19
Linear donor constructs for targeted integration App 20110281361 - DeKelver; Russell ; et al.	2011-11-17
Genome editing of a Rosa locus using nucleases App 20110265198 - Gregory; Philip D. ; et al.	2011-10-27
Rapid screening of biologically active nucleases and isolation of nuclease-modified cells App 20110244474 - Holmes; Michael C. ; et al.	2011-10-06
Targeted disruption of T cell receptor genes using engineered zinc finger protein nucleases App 20110158957 - Bonini; Maria Chiara ; et al.	2011-06-30
Methods and compositions for modulating PD1 App 20110136895 - Gregory; Philip D. ; et al.	2011-06-09
Methods and compositions for gene inactivation Grant 7,951,925 - Ando , et al. May 31, 2	2011-05-31
Engineered cleavage half-domains Grant 7,914,796 - Miller , et al. March 29, 2	2011-03-29
Methods and compositions for targeted cleavage and recombination Grant 7,888,121 - Urnov , et al. February 15, 2	2011-02-15
Targeted integration into stem cells App 20110027235 - Gregory; Philip D. ; et al.	2011-02-03
Methods and compositions for targeted cleavage and recombination App 20110030076 - Urnov; Fyodor ; et al.	2011-02-03
Rapid screening of biologically active nucleases and isolation of nuclease-modified cells App 20110014616 - HOLMES; MICHAEL C. ; et al.	2011-01-20
Modification of CXCR4 using engineered zinc finger proteins App 20100291048 - Holmes; Michael C. ; et al.	2010-11-18
Methods and compositions for gene inactivation App 20100111907 - Ando; Dale ; et al.	2010-05-06
Linear donor constructs for targeted integration App 20090263900 - DeKelver; Russell ; et al.	2009-10-22
Methods and compositions for targeted integration App 20090117617 - Holmes; Michael C. ; et al.	2009-05-07
Methods and compositions for increased transgene expression App 20080311095 - Holmes; Michael C. ; et al.	2008-12-18
Methods and compositions for modification of the human glucocorticoid receptor locus App 20080188000 - Reik; Andreas ; et al.	2008-08-07
Methods and compositions for gene inactivation App 20080159996 - Ando; Dale ; et al.	2008-07-03
Targeted integration and expression of exogenous nucleic acid sequences App 20070134796 - Holmes; Michael C. ; et al.	2007-06-14
Targeted deletion of cellular DNA sequences App 20060188987 - Guschin; Dmitry ; et al.	2006-08-24
Methods and compositions for targeted cleavage and recombination App 20050064474 - Urnov, Fyodor ; et al.	2005-03-24

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