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N-[4-(1h-pyrazolo[3,4-b]pyrazin-6-yl)-phenyl]-sulfonamides And Their Use As Pharmaceuticals App 20140288083 - Nazare; Marc ;   et al. | 2014-09-25 |
Cyclohexylamine isoquinolone derivatives Grant 8,796,458 - Plettenburg , et al. August 5, 2 | 2014-08-05 |
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Cycloalkylamine substituted isoquinolone derivatives Grant 8,742,116 - Plettenburg , et al. June 3, 2 | 2014-06-03 |
Isoquinoline derivatives Grant 8,722,671 - Plettenburg , et al. May 13, 2 | 2014-05-13 |
Cycloalkylamine substituted isoquinoline derivatives Grant 8,710,228 - Plettenburg , et al. April 29, 2 | 2014-04-29 |
Cyclohexylamin isoquinolone derivatives Grant 8,609,691 - Plettenburg , et al. December 17, 2 | 2013-12-17 |
Isoquinoline derivatives Grant 8,501,736 - Plettenburg , et al. August 6, 2 | 2013-08-06 |
Substituted isoquinoline and isoquinolinone derivatives Grant 8,461,144 - Plettenburg , et al. June 11, 2 | 2013-06-11 |
N-[4-(1H-PYRAZOLO[3,4-b]PYRAZIN-6-YL)-PHENYL]-SULFONAMIDES AND THEIR USE AS PHARMACEUTICALS App 20130072493 - NAZARE; Marc ;   et al. | 2013-03-21 |
Substituted Isoquinolineand Isoquinolinone Derivatives App 20120316152 - Plettenburg; Oliver ;   et al. | 2012-12-13 |
Substituted isoquinoline and isoquinolinone derivatives as inhibitors of Rho-kinase Grant 8,278,294 - Plettenburg , et al. October 2, 2 | 2012-10-02 |
Piperidinyl-substituted isoquinolone derivatives Grant 8,188,117 - Plettenburg , et al. May 29, 2 | 2012-05-29 |
N-substituted (benzoimidazol-2-yl)phenylamines, processes for their preparation, their use as a medicament or diagnostic aid, and a medicament comprising them Grant 8,067,614 - Heinelt , et al. November 29, 2 | 2011-11-29 |
Tetrahydrofuran derivatives for use as inhibitors of matrix metalloproteinases Grant 8,039,481 - Schudok , et al. October 18, 2 | 2011-10-18 |
Cyclohexylamin Isoquinolone Derivatives App 20110251226 - Plettenburg; Oliver ;   et al. | 2011-10-13 |
Isoquinoline Derivatives App 20110245248 - Plettenburg; Oliver ;   et al. | 2011-10-06 |
Substituted Tetrahydro-2h-isoquinolin-1-one Derivatives, And Methods For The Production And Use Thereof App 20110021462 - PEUKERT; Stefan ;   et al. | 2011-01-27 |
Substituted 4-phenyltetrahydroisoquinolines, pharmaceutical compositions comprising them and therapeutic methods for their use Grant 7,868,003 - Heinelt , et al. January 11, 2 | 2011-01-11 |
Imino-imidazo-pyridine derivatives having antithrombotic activity Grant 7,863,269 - Heinelt , et al. January 4, 2 | 2011-01-04 |
Substituted 2-pyridone derivatives, method for their preparation and their use as medicament Grant 7,863,280 - Peukert , et al. January 4, 2 | 2011-01-04 |
Substituted tetrahydroisochinolines as MMP inhibitors, related production method and use as medicine Grant 7,858,619 - Hofmeister , et al. December 28, 2 | 2010-12-28 |
Substituted tetrahydro-2H-isoquinolin-1-one derivatives, and methods for the production and use thereof Grant 7,795,278 - Peukert , et al. September 14, 2 | 2010-09-14 |
Substituted 4-phenyltetrahydroisoquinolines, pharmaceutical compositions thereof, methods for their preparation and therapeutic use Grant 7,790,742 - Lang , et al. September 7, 2 | 2010-09-07 |
Substituted thiophenes: compositions, processes of making, and uses in disease treatment and diagnosis Grant 7,763,643 - Lang , et al. July 27, 2 | 2010-07-27 |
N-Substituted (Benzoimidazol-2-yl)phenylamines, Processes for Their Preparation, Their Use as a Medicament or Diagnostic Aid, and a Medicament Comprising Them App 20100168196 - HEINELT; Uwe ;   et al. | 2010-07-01 |
Substituted isoquinoline and isoquinolinone derivatives App 20100105650 - PLETTENBURG; Oliver ;   et al. | 2010-04-29 |
4-trifluoromethoxyphenoxybenzol-4'-sulfonic Acids, Method For The Production And Use Thereof In Medicaments App 20100099663 - SCHUDOK; Manfred ;   et al. | 2010-04-22 |
Cycloalkylamine substituted isoquinoline derivatives App 20100081671 - PLETTENBURG; Oliver ;   et al. | 2010-04-01 |
Substituted isoquinoline and isoquinolinone derivatives as inhibitors of RHO-Kinase App 20100063025 - PLETTENBURG; Oliver ;   et al. | 2010-03-11 |
Cycloalkylamine Substituted Isoquinolone Derivatives App 20100056518 - PLETTENBURG; Oliver ;   et al. | 2010-03-04 |
Cycloalkylamine substituted isoquinolone and isoquinolinone derivatives App 20100056568 - PLETTENBURG; Oliver ;   et al. | 2010-03-04 |
Isoindolone derivatives, preparation process and intermediates of this process, their use as medicaments, and pharmaceutical compositions comprising them Grant 7,589,117 - Kleemann , et al. September 15, 2 | 2009-09-15 |
Imino-imidazo-pyridine Derivatives Having Antithrombotic Activity App 20090192150 - HEINELT; Uwe ;   et al. | 2009-07-30 |
Substituted Thiophenes: Compositions, Processes Of Making, And Uses In Disease Treatment And Diagnosis App 20090137630 - LANG; Hans-Jochen ;   et al. | 2009-05-28 |
Piperidinyl-substituted isoquinolone derivatives App 20090093518 - Plettenburg; Oliver ;   et al. | 2009-04-09 |
Isoquinoline Derivatives App 20090088429 - PLETTENBURG; Oliver ;   et al. | 2009-04-02 |
Substituted thiophenes: compositions, processes of making, and uses in disease treatment and diagnosis Grant 7,488,746 - Lang , et al. February 10, 2 | 2009-02-10 |
Novel Substituted 2-aminoimidazoles, Process For Their Preparation, Their Use As Medicament Or Diagnostic Aid App 20080275098 - HEINELT; Uwe ;   et al. | 2008-11-06 |
Substituted 2-aminoimidazoles, process for their preparation, their use as medicament or diagnostic aid Grant 7,442,717 - Heinelt , et al. October 28, 2 | 2008-10-28 |
Cyclohexylamin isoquinolone derivatives App 20080242699 - PLETTENBURG; Oliver ;   et al. | 2008-10-02 |
Methods For The Improvement Of Memory And Neurological Function Comprising The Administration Of Compositions That Act As Inhibitors Of The Sodium Proton (na+ /h+ ) Exchanger, Subtype 5 (nhe-5) App 20080234317 - KLEEMANN; Heinz-Werner ;   et al. | 2008-09-25 |
Thieno-imino acid derivatives for use as matrix metalloproteinase inhibitors Grant 7,399,770 - Schudok , et al. July 15, 2 | 2008-07-15 |
N-Substituted (Benzoimidazol-2-yl)phenylamines, Processes for Their Preparation, Their Use as a Medicament or Diagnostic Aid, and a Medicament Comprising Them App 20080167359 - HEINELT; Uwe ;   et al. | 2008-07-10 |
Substituted Tetrahydroisochinolines As Mmp Inhibitors, Related Production Method And Use As Medicine App 20080090821 - HOFMEISTER; Armin ;   et al. | 2008-04-17 |
Substituted Thiophenes: Compositions, Processes Of Making, And Uses In Disease Treatment And Diagnosis App 20080070947 - LANG; Hans-Jochen ;   et al. | 2008-03-20 |
Substituted 4-phenyltetrahydroisoquinolines, Pharmaceuitcal Compositions Comprising Them And Therapeutic Methods For Their Use App 20080058328 - HEINELT; Uwe ;   et al. | 2008-03-06 |
Tetrahydrofuran Derivatives For Use As Inhibitors Of Matrix Metalloproteinases App 20080039489 - SCHUDOK; Manfred ;   et al. | 2008-02-14 |
Substituted thiophenes: compositions, processes of making, and uses in disease treatment and diagnosis Grant 7,317,033 - Lang , et al. January 8, 2 | 2008-01-08 |
Substituted 2-pyridone Derivatives, Method For Their Preparation And Their Use As Medicament App 20070281948 - PEUKERT; Stefan ;   et al. | 2007-12-06 |
Substituted 4-phenyltetrahyrdoisoquinolines, Pharmaceutical Compositions Thereof, Methods For Their Preparation And Therapeutic Use App 20070225323 - LANG; Hans-Jochen ;   et al. | 2007-09-27 |
Substituted Tetrahydroisoquinolines Used In The Form Of Mmp Inhibitors, Method For The Production And Use Thereof In The Form Of Drugs App 20070203118 - Hofmeister; Armin ;   et al. | 2007-08-30 |
Composition, process of making, and medical use of substituted 4-phenyltetrahydroisoquinolines Grant 7,241,775 - Hofmeister , et al. July 10, 2 | 2007-07-10 |
4-Trifluoromethoxyphenoxybenzol-4-Sulfonic Acids, Method For The Production And Use Thereof In Medicaments App 20070155778 - Schudok; Manfred ;   et al. | 2007-07-05 |
Substituted Tetrahydro-2h-isoquinolin-1-one Derivatives, And Methods For The Production And Use Thereof App 20070142430 - PEUKERT; Stefan ;   et al. | 2007-06-21 |
Thieno-imino Acid Derivatives For Use As Matrix Metalloproteinase Inhibitors App 20070093482 - SCHUDOK; Manfred ;   et al. | 2007-04-26 |
Bicyclic imino acid derivatives as inhibitors of matrix metalloproteinases Grant 7,205,315 - Schudok , et al. April 17, 2 | 2007-04-17 |
Substituted imidazolidines, process for their preparation, and their use as a medicament or diagnostic, and medicament comprising them Grant 7,179,829 - Heinelt , et al. February 20, 2 | 2007-02-20 |
Substituted thiophenes: compositions, processes of making, and uses in disease treatment and diagnosis App 20060160873 - Lang; Hans-Jochen ;   et al. | 2006-07-20 |
Isoindolone derivatives, preparation process and intermediates of this process, their use as medicaments, and pharmaceutical compositions comprising them Grant 7,078,428 - Kleemann , et al. July 18, 2 | 2006-07-18 |
Isoindolone derivatives, preparation process and intermediates of this process, their use as medicaments, and pharmaceutical compositions comprising them App 20060148880 - Kleemann; Heinz-Werner ;   et al. | 2006-07-06 |
Substituted thiophenes: compositions, processes of making, and uses in disease treatment and diagnosis Grant 7,049,333 - Lang , et al. May 23, 2 | 2006-05-23 |
Substituted benzimidazoles, processes for their preparation, their use as medicaments, and medicaments comprising them Grant 6,958,357 - Hofmeister , et al. October 25, 2 | 2005-10-25 |
Substituted 4-phenyltetrahydroisoquinolinium, process for their preparation, their use as a medicament, and medicament containing them Grant 6,911,453 - Hofmeister , et al. June 28, 2 | 2005-06-28 |
Bicyclic imino acid derivatives as inhibitors of matrix metalloproteinases App 20050080127 - Schudok, Manfred ;   et al. | 2005-04-14 |
N-substituted (benzoimidazol-2-yl) phenylamines, process for their preparation, their use as medicament or diagnostic aid, and medicament comprising them App 20050054705 - Heinelt, Uwe ;   et al. | 2005-03-10 |
Composition, process of making, and medical use of substituted 4-phenyltetrahydroisoquinolines App 20050009863 - Hofmeister, Armin ;   et al. | 2005-01-13 |
Substituted 4-phenyltetrahydroisoquinolinium, process for their preparation, their use as a medicament, and medicament containing them App 20050009864 - Hofmeister, Armin ;   et al. | 2005-01-13 |
Substituted imidazolidines, process for their preparation, and their use as a medicament or diagnostic, and medicament comprising them App 20050004198 - Heinelt, Uwe ;   et al. | 2005-01-06 |
Novel substituted 2-aminoimidazoles, process for their preparation, their use as medicament or diagnostic aid App 20040259927 - Heinelt, Uwe ;   et al. | 2004-12-23 |
Isoindolone derivatives, preparation process and intermediates of this process, their use as medicaments, and pharmaceutical compositions comprising them App 20040048916 - Kleemann, Heinz-Werner ;   et al. | 2004-03-11 |
Substituted 4-phenyltetrahydroisoquinolinium salts, process for their preparation, their use as a medicament, and medicament containing them Grant 6,703,405 - Hofmeister , et al. March 9, 2 | 2004-03-09 |
Substituted 4-phenyltetrahydroisoquinolinium, process for their preparation, their use as a medicament, and medicament containing them App 20040044211 - Hofmeister, Armin ;   et al. | 2004-03-04 |
Substituted benzimidazoles, processes for their preparation, their use as medicaments, and medicaments comprising them Grant 6,686,384 - Hofmeister , et al. February 3, 2 | 2004-02-03 |
Substituted thiophenes: compositions, processes of making, and uses in disease treatment and diagnosis App 20040006119 - Lang, Hans-Jochen ;   et al. | 2004-01-08 |
Substituted benzimidazoles, processes for their preparation, their use as medicaments, and medicaments comprising them App 20030191170 - Hofmeister, Armin ;   et al. | 2003-10-09 |
Substituted imidazolidines, process for their preparation, and their use as a medicament or diagnostic App 20030187045 - Heinelt, Uwe ;   et al. | 2003-10-02 |
Substituted 4-phenyltetrahydroisoquinolinium salts, process for their preparation, their use as a medicament, and medicament containing them App 20030171580 - Hofmeister, Armin ;   et al. | 2003-09-11 |
Substituted benzimidazoles, processes for their preparation, their use as medicaments, and medicaments comprising them App 20020132842 - Hofmeister, Armin ;   et al. | 2002-09-19 |
Substituted acylguanidines, process for their preparation, their use as medicaments or diagnostics, and medicaments comprising them Grant 6,451,781 - Kleemann , et al. September 17, 2 | 2002-09-17 |
Substituted cinnamic, acid guanidides, process for their preparation, their use as a medicament, and medicament comprising them Grant 6,399,824 - Hofmeister , et al. June 4, 2 | 2002-06-04 |
Substituted Cinnamic, Acid Guanidides, Process For Their Preparation, Their Use As A Medicament, And Medicament Comprising Them App 20020058710 - Hofmeister, Armin, ;   et al. | 2002-05-16 |
Substituted 4-benzylaminoquinolines and their hetero analogs, process for their preparation, pharmaceuticals containing these compounds and use thereof Grant 6,339,077 - Hofmeister , et al. January 15, 2 | 2002-01-15 |