Patent | Date |
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Heteroaryl inhibitors of PDE4 Grant 11,401,286 - Gurney , et al. August 2, 2 | 2022-08-02 |
PDE4D inhibitors Grant 11,104,660 - Gurney , et al. August 31, 2 | 2021-08-31 |
Salts and polymorphs of a PDE4 inhibitor Grant 11,028,050 - Gurney , et al. June 8, 2 | 2021-06-08 |
Heteroaryl Inhibitors Of Pde4 App 20200354384 - GURNEY; Mark E. ;   et al. | 2020-11-12 |
Pde4d Inhibitors App 20200339532 - Gurney; Mark E. ;   et al. | 2020-10-29 |
Salts And Polymorphs Of A Pde4 Inhibitor App 20200331858 - Gurney; Mark E. ;   et al. | 2020-10-22 |
Heteroaryl inhibitors of PDE4 Grant 10,626,129 - Gurney , et al. | 2020-04-21 |
Heteroaryl Inhibitors Of Pde4 App 20190270759 - GURNEY; Mark E. ;   et al. | 2019-09-05 |
Heteroaryl inhibitors of PDE4 Grant 10,364,258 - Gurney , et al. | 2019-07-30 |
Heteroaryl Inhibitors Of Pde4 App 20190055269 - GURNEY; Mark E. ;   et al. | 2019-02-21 |
Heteroaryl inhibitors of PDE4 Grant 10,093,686 - Gurney , et al. October 9, 2 | 2018-10-09 |
Heteroaryl Inhibitors Of Pde4 App 20170342094 - GURNEY; Mark E. ;   et al. | 2017-11-30 |
Heteroaryl inhibitors of PDE4 Grant 9,777,024 - Gurney , et al. October 3, 2 | 2017-10-03 |
2,4-Diaminoquinazolines for Spinal Muscular Atrophy App 20160152577 - Singh; Jasbir ;   et al. | 2016-06-02 |
Heteroaryl Inhibitors Of Pde4 App 20160137672 - Gurney; Mark E. ;   et al. | 2016-05-19 |
Heteroaryl inhibitors of PDE4 Grant 9,221,843 - Gurney , et al. December 29, 2 | 2015-12-29 |
2,4-Diaminoquinazolines for spinal muscular atrophy Grant 9,067,897 - Singh , et al. June 30, 2 | 2015-06-30 |
Heteroaryl Inhibitors Of Pde4 App 20150119362 - Gurney; Mark E. ;   et al. | 2015-04-30 |
Substituted benzoazole PDE4 inhibitors for treating inflammatory, cardiovascular and CNS disorders Grant 8,883,833 - Singh , et al. November 11, 2 | 2014-11-11 |
4-(or 5-) substituted catechol derivatives Grant 8,877,816 - Singh , et al. November 4, 2 | 2014-11-04 |
Selective PDE4 B inhibition and improvement in cognition in subjects with brain injury Grant 8,865,723 - Gurney , et al. October 21, 2 | 2014-10-21 |
Biaryl Pde4 Inhibitors For Treating Inflammatory, Cardiovascular And Cns Disorders App 20140301999 - Singh; Jasbir ;   et al. | 2014-10-09 |
Substituted Benzoazole Pde4 Inhibitors For Treating Pulmonary And Cardiovascular Disorders App 20140275553 - SINGH; Jasbir ;   et al. | 2014-09-18 |
Biaryl PDE4 inhibitors for treating inflammatory, cardiovascular and CNS disorders Grant 8,791,267 - Singh , et al. July 29, 2 | 2014-07-29 |
Selective Pde4 B Inhibition And Improvement In Cognition In Subjects With Brain Injury App 20140121221 - Gurney; Mark E. ;   et al. | 2014-05-01 |
Biaryl Pde4 Inhibitors For Treating Pulmonary And Cardiovascular Disorders App 20120213758 - SINGH; Jasbir ;   et al. | 2012-08-23 |
Substituted Benzoazole Pde4 Inhibitors For Treating Pulmonary And Cardiovascular Disorders App 20120207729 - SINGH; Jasbir ;   et al. | 2012-08-16 |
Biaryl Pde4 Inhibitors For Treating Inflammatory, Cardiovascular And Cns Disorders App 20120183522 - Singh; Jasbir ;   et al. | 2012-07-19 |
Methods of diagnosing susceptibility to myocardial infarction and screening for an LTA4H haplotype Grant 8,158,362 - Helgadottir , et al. April 17, 2 | 2012-04-17 |
Pyrazolylphenyl and pyrrolylphenyl inhibitors of LTA4H for treating inflammation Grant 8,115,005 - Sandanayaka , et al. February 14, 2 | 2012-02-14 |
Alzheimer's Disease Secretase, APP Substrates Therefor, and Uses Therefor App 20110294149 - Gurney; Mark E. ;   et al. | 2011-12-01 |
Aryl amino acid derivatives as inhibitors for treating inflammation Grant 7,989,480 - Sandanayaka , et al. August 2, 2 | 2011-08-02 |
2,4-diaminoquinazolines for spinal muscular atrophy Grant 7,985,755 - Singh , et al. July 26, 2 | 2011-07-26 |
2,4-Diaminoquinazolines for Spinal Muscular Atrophy App 20110112118 - Singh; Jasbir ;   et al. | 2011-05-12 |
Substrates and assays for .beta.-secretase Grant 7,888,291 - Yan , et al. February 15, 2 | 2011-02-15 |
2,4-diaminoquinazolines for spinal muscular atrophy Grant 7,888,366 - Singh , et al. February 15, 2 | 2011-02-15 |
Alzheimer's disease secretase Grant 7,812,123 - Gurney , et al. October 12, 2 | 2010-10-12 |
Substrates and assays for .beta.-secretase Grant 7,803,739 - Yan , et al. September 28, 2 | 2010-09-28 |
Susceptibility Gene for Myocardial Infarction, Stroke, and PAOD; Methods of Treatment App 20100216863 - Helgadottir; Anna ;   et al. | 2010-08-26 |
Biaryl nitrogen-heterocycle inhibitors of LTA4H for treating inflammation Grant 7,750,012 - Sandanayaka , et al. July 6, 2 | 2010-07-06 |
Phenoxymethylalkyne inhibitors of LTA4H for treating inflammation Grant 7,728,032 - Sandanayaka , et al. June 1, 2 | 2010-06-01 |
N-linked aryl heteroaryl inhibitors of LTA4H for treating inflammation Grant 7,674,802 - Sandanayaka , et al. March 9, 2 | 2010-03-09 |
Biaryl Pde4 Inhibitors For Treating Inflammatory, Cardiovascular And Cns Disorders App 20090324569 - Singh; Jasbir ;   et al. | 2009-12-31 |
Sulfonamide Peri-substituted Bicyclics For Occlusive Artery Disease App 20090291948 - Singh; Jasbir ;   et al. | 2009-11-26 |
Sulfonamide peri-substituted bicyclics for occlusive artery disease Grant 7,598,397 - Singh , et al. October 6, 2 | 2009-10-06 |
Biaryl Substituted Nitrogen Containing Heterocycle Inhibitors Of Lta4h For Treating Inflammation App 20090233969 - Sandanayaka; Vincent ;   et al. | 2009-09-17 |
Biaryl substituted nitrogen containing heterocycle inhibitors of LTA4H for treating inflammation Grant 7,576,102 - Sandanayaka , et al. August 18, 2 | 2009-08-18 |
Biaryl Pde4 Inhibitors For Treating Pulmonary And Cardiovascular Disorders App 20090136473 - Singh; Jasbir ;   et al. | 2009-05-28 |
4- (or 5-) Substituted Catechol Derivatives App 20090131530 - Singh; Jasbir ;   et al. | 2009-05-21 |
Substituted Benzoazole Pde4 Inhibitors For Treating Inflammatory, Cardiovascular And Cns Disorders App 20090130077 - Singh; Jasbir ;   et al. | 2009-05-21 |
Substituted Benzoazole Pde4 Inhibitors For Treating Pulmonary And Cardiovascular Disorders App 20090130076 - Singh; Jasbir ;   et al. | 2009-05-21 |
Alzheimer's Disease Secretase, APP Substrates Therefor and Uses Therefor App 20090075316 - Gurney; Mark E. ;   et al. | 2009-03-19 |
2,4-diaminoquinazolines For Spinal Muscular Atrophy App 20090042900 - Singh; Jasbir ;   et al. | 2009-02-12 |
Sustained Release Formulation and Dosing Schedules of Leukotriene Synthesis Inhibitor for Human Therapy App 20090030037 - Gurney; Mark E. ;   et al. | 2009-01-29 |
Substrates and assays for beta-secretase activity App 20080299596 - Yan; Riqiang ;   et al. | 2008-12-04 |
Susceptibility Gene for Myocardial Infarction, Stroke, Paod and Methods of Treatment App 20080293750 - Helgadottir; Anna ;   et al. | 2008-11-27 |
Alzheimer's disease secretase, APP substrates thereof, and uses thereof Grant 7,456,269 - Gurney , et al. November 25, 2 | 2008-11-25 |
Alzheimer's Disease Secretase, APP Substrates Therefor and Uses Therefor App 20080171349 - Gurney; Mark E. ;   et al. | 2008-07-17 |
Methods of diagnosis and treatment for asthma, allergic rhinitis and other respiratory diseases based on haplotype association App 20080146540 - Hakonarson; Hakon ;   et al. | 2008-06-19 |
Alzheimer's disease secretase, APP substrates therefor, and uses therefor Grant 7,378,511 - Gurney , et al. May 27, 2 | 2008-05-27 |
Alzheimer's disease secretase, APP substrates therefor, and uses therefor Grant 7,375,187 - Gurney , et al. May 20, 2 | 2008-05-20 |
Alzheimer's disease secretase, APP substrates therefor, and uses therefor Grant 7,368,536 - Gurney , et al. May 6, 2 | 2008-05-06 |
Substrates and Assays for Beta Secretase Activity App 20080090260 - Yan; Riqiang ;   et al. | 2008-04-17 |
Phenoxymethylalkyne Inhibitors Of Lta4h For Treating Inflammation App 20080090839 - Sandanayaka; Vincent ;   et al. | 2008-04-17 |
Pyrazolylphenyl And Pyrrolylphenyl Inhibitors Of Lta4h For Treating Inflammation App 20080033013 - Sandanayaka; Vincent ;   et al. | 2008-02-07 |
Aryl Amino Acid Derivatives As Inhibitors For Treating Inflammation App 20080033024 - Sandanayaka; Vincent ;   et al. | 2008-02-07 |
Transgenic mice knockouts of BACE-1 Grant 7,309,811 - McConlogue , et al. December 18, 2 | 2007-12-18 |
Susceptibility gene for myocardial infarction, stroke, and PAOD; methods of treatment App 20070280917 - Helgadottir; Anna ;   et al. | 2007-12-06 |
Biaryl Nitrogen-heterocycle Inhibitors Of Lta4h For Treating Inflammation App 20070149544 - SANDANAYAKA; Vincent ;   et al. | 2007-06-28 |
Biaryl Substituted Nitrogen Containing Heterocycle Inhibitors Of Lta4h For Treating Inflammation App 20070142432 - Sandanayaka; Vincent ;   et al. | 2007-06-21 |
N-linked Aryl Heteroaryl Inhibitors Of Lta4h For Treating Inflammation App 20070142434 - Sandanayaka; Vincent ;   et al. | 2007-06-21 |
Substrates and assays for .beta.-secretase activity Grant 7,205,120 - Yan , et al. April 17, 2 | 2007-04-17 |
Sustained release formulation and dosing schedule of leukotriene synthesis inhibitor for human therapy App 20060257481 - Gurney; Mark E. ;   et al. | 2006-11-16 |
Alzheimer's disease secretase, APP substrates therefor, and uses thereof Grant 7,041,473 - Gurney , et al. May 9, 2 | 2006-05-09 |
Sulfonamide peri-substituted bicyclics for occlusive artery disease App 20060079520 - Singh; Jasbir ;   et al. | 2006-04-13 |
Materials and methods for identifying anti-schizophrenic agents App 20060029546 - Gurney; Mark E. ;   et al. | 2006-02-09 |
Susceptibility gene for myocardial infarction, stroke, and PAOD, methods of treatment App 20060019269 - Helgadottir; Anna ;   et al. | 2006-01-26 |
Methods of diagnosis and treatment for asthma and other respiratory diseases based on haplotype association App 20060014165 - Hakonarson; Hakon ;   et al. | 2006-01-19 |
2,4-diaminoquinazolines for spinal muscular atrophy App 20050288314 - Singh, Jasbir ;   et al. | 2005-12-29 |
Human schizophrenia gene App 20050208527 - Stefansson, Hreinn ;   et al. | 2005-09-22 |
Alzheimer's disease secretase, APP substrates therefor, and uses therefor Grant 6,913,918 - Gurney , et al. July 5, 2 | 2005-07-05 |
Human sel-10 polypeptides and polynucleotides that encode them App 20050095671 - Gurney, Mark E. ;   et al. | 2005-05-05 |
Substrates and assays for beta-secretase App 20050096457 - Yan, Riqiang ;   et al. | 2005-05-05 |
Alzheimer's disease secretase, app substrates therefor, and uses therefor App 20050080232 - Gurney, Mark E. ;   et al. | 2005-04-14 |
Alzheimer's disease secretase, APP substrates therefor, and uses thereof Grant 6,867,018 - Gurney , et al. March 15, 2 | 2005-03-15 |
Alzheimer's disease secretase App 20050026256 - Gurney, Mark E. ;   et al. | 2005-02-03 |
Alzheimer's disease secretase Grant 6,835,565 - Gurney , et al. December 28, 2 | 2004-12-28 |
Substrates and assays for beta-secretase App 20040254341 - Yan, Riqiang ;   et al. | 2004-12-16 |
Substrates and assays for beta-secretase App 20040254342 - Yan, Riqiang ;   et al. | 2004-12-16 |
Substrates and assays for beta-secretase App 20040253706 - Yan, Riqiang ;   et al. | 2004-12-16 |
Alzheimer's disease secretase, APP substrates therefor, and uses therefor Grant 6,828,117 - Gurney , et al. December 7, 2 | 2004-12-07 |
Substrates and assays for beta-secretase App 20040241792 - Yan, Riqiang ;   et al. | 2004-12-02 |
Alzheimer's disease secretase, APP substrates therefor, and uses therefor Grant 6,825,023 - Gurney , et al. November 30, 2 | 2004-11-30 |
Alzheimer's disease secretase, app substrates therefor, and uses therefor App 20040234976 - Gurney, Mark E. ;   et al. | 2004-11-25 |
Polynucleotides encoding alzheimer's disease secretase Grant 6,797,487 - Gurney , et al. September 28, 2 | 2004-09-28 |
Alzheimer's disease, secretase, APP substrates therefor, and uses therefor Grant 6,790,610 - Gurney , et al. September 14, 2 | 2004-09-14 |
Alzheimer's disease secretase, app substrates therefor, and uses therefor App 20040166507 - Gurney, Mark E. ;   et al. | 2004-08-26 |
Alzheimer's disease secretase, APP substrates therefor, and uses therefor Grant 6,753,163 - Gurney , et al. June 22, 2 | 2004-06-22 |
Human sel-10 polypeptides and polynucleotides that encode them App 20040115700 - Gurney, Mark E. ;   et al. | 2004-06-17 |
Human sel-10 polypeptides and polynucleotides that encode them App 20040116672 - Gurney, Mark E. ;   et al. | 2004-06-17 |
Human sel-10 polypeptides and polynucleotides that encode them App 20040110202 - Gurney, Mark E. ;   et al. | 2004-06-10 |
Alzheimer's disease secretase, APP substrates therefor, and uses thereof Grant 6,737,510 - Gurney , et al. May 18, 2 | 2004-05-18 |
Human sel-10 polypeptides and polynucleotides that encode them Grant 6,730,778 - Gurney , et al. May 4, 2 | 2004-05-04 |
Alzheimer's disease secretase, APP substrates therefor, and uses therefor Grant 6,727,074 - Gurney , et al. April 27, 2 | 2004-04-27 |
Method of identifying agents that inhibit APP processing activity Grant 6,706,485 - Gurney , et al. March 16, 2 | 2004-03-16 |
Alzheimer's disease secretase, APP substrates therefor, and uses therefor App 20040043408 - Gurney, Mark E. ;   et al. | 2004-03-04 |
Alzheimer's disease secretase, APP substrates therefor, and uses therefor Grant 6,699,671 - Gurney , et al. March 2, 2 | 2004-03-02 |
Human sel-10 polypeptides and polynucleotides that encode them Grant 6,638,731 - Gurney , et al. October 28, 2 | 2003-10-28 |
Method of reducing cellular production of amyloid beta App 20030104365 - Gurney, Mark E. ;   et al. | 2003-06-05 |
Alzheimer's disease, secretase, app substrates therefor, and uses therefor App 20030077226 - Gurney, Mark E ;   et al. | 2003-04-24 |
Substrates and assays for beta-secretase activity App 20030017991 - Yan, Riqiang ;   et al. | 2003-01-23 |
Transgenic knockouts of BACE-1 App 20020194632 - McConlogue, Lisa ;   et al. | 2002-12-19 |
Human Sel-10 Polypeptides And Polynucleotides That Encode Them App 20020177187 - GURNEY, MARK E. ;   et al. | 2002-11-28 |
Human Sel-10 Polypeptides And Polynucleotides That Encode Them App 20020164683 - GURNEY, MARK E. ;   et al. | 2002-11-07 |
Alzheimer's disease secretase, APP substrates therefor, and uses therefor Grant 6,440,698 - Gurney , et al. August 27, 2 | 2002-08-27 |
Alzheimer's disease secretase, APP substrates therefor, and uses thereof Grant 6,420,534 - Gurney , et al. July 16, 2 | 2002-07-16 |
Alzheimer's disease secretase, APP substrates therefor, and uses therefor App 20020081634 - Gurney, Mark E. ;   et al. | 2002-06-27 |
Alzheimer's disease secretase, APP substrates therefor, and uses therefor App 20020064819 - Gurney, Mark E. ;   et al. | 2002-05-30 |
Alzheimer's disease secretase, APP substrates therefor, and uses therefor App 20020037315 - Gurney, Mark E. ;   et al. | 2002-03-28 |
Transgenic mouse model of human neurodegenerative disease App 20020010947 - Gurney, Mark E. ;   et al. | 2002-01-24 |
Alzheimer's disease secretase, APP substrates therefor, and uses therefor App 20010021391 - Gurney, Mark E. ;   et al. | 2001-09-13 |
Alzheimer's disease secretase, APP substrates therefor, and uses therefor App 20010018208 - Gurney, Mark E. ;   et al. | 2001-08-30 |
Alzheimer's disease secretase, APP substrates therefor, and uses therefor App 20010016324 - Gurney, Mark E. ;   et al. | 2001-08-23 |