Patent | Date |
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Substituted Pyrrolidine Amides Ii App 20220127264 - JAKOB; Florian ;   et al. | 2022-04-28 |
Pharmaceutical composition comprising (1R,4R)-6'- fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro [cyclohexane-1,1'-pyrano- [3,4,b ]indol] -4-amine and paracetamol or propacetamol Grant 11,311,504 - Frosch , et al. April 26, 2 | 2022-04-26 |
Substituted Pyrrolidine Amides V App 20220106294 - JAKOB; Florian ;   et al. | 2022-04-07 |
Substituted Pyrrolidine Amides Iv App 20220106295 - JAKOB; Florian ;   et al. | 2022-04-07 |
Treatment of Irritable Bowel Syndrome App 20210212967 - SCHIENE; Klaus ;   et al. | 2021-07-15 |
Stable formulation for parenteral administration of tapentadol Grant 11,013,701 - Schiller , et al. May 25, 2 | 2021-05-25 |
Prolonged release pharmaceutical composition containing 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)phenol Grant 11,007,156 - Bartholomaeus , et al. May 18, 2 | 2021-05-18 |
Pharmaceutical dosage forms comprising 6'-fluoro-(N-methyl- or N,N-dimethyl-)-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano[3- ,4,b]indol]-4-amine Grant 10,912,763 - Gruening , et al. February 9, 2 | 2021-02-09 |
Stable formulation for parenteral administration of Tapentadol Grant 10,898,452 - Ellermann , et al. January 26, 2 | 2021-01-26 |
3-((hetero-)aryl)-alkyl-8-amino-2-oxo-l,3-diaza-spiro-[4.5]-decane derivatives Grant 10,829,480 - Kuehnert , et al. November 10, 2 | 2020-11-10 |
Pharmaceutical combination Grant 10,813,890 - Schiene , et al. October 27, 2 | 2020-10-27 |
8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives Grant 10,793,556 - Kuehnert , et al. October 6, 2 | 2020-10-06 |
Device and formulation for topical treatment of pain affecting the vulvar area of the female human genital organ Grant 10,765,848 - Dimino , et al. Sep | 2020-09-08 |
Substituted Pyrrolidine Amides Iii App 20200223840 - JAKOB; Florian ;   et al. | 2020-07-16 |
Pharmaceutical device for electric-field assisted administration of Tapentadol and method of administering Tapentadol with same Grant 10,632,195 - Friedrich , et al. | 2020-04-28 |
Substituted pyrrolidine amides I Grant 10,626,106 - Jakob , et al. | 2020-04-21 |
Prolonged Release Pharmaceutical Composition Containing 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)phenol App 20200038344 - BARTHOLOMAEUS; Johannes ;   et al. | 2020-02-06 |
3-((hetero-)aryl)-alkyl-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane Derivatives App 20200002319 - KUEHNERT; Sven ;   et al. | 2020-01-02 |
Pharmaceutical Composition Comprising (1r,4r)-6'-fluoro-n,n-dimethyl-4-phenyl-4',9'-dihydro-3'h-spiro [cyclohexane-1,1'-pyrano-[ App 20190350884 - FROSCH; Stefanie ;   et al. | 2019-11-21 |
Combination of selected analgesics and COX-II inhibitors Grant 10,471,079 - Schiene , et al. Nov | 2019-11-12 |
Transdermal Administration Of Memantine App 20190298662 - EIFLER; Rene ;   et al. | 2019-10-03 |
Treatment of Pain Associated with Trigeminal Neuralgia App 20190274974 - CHRISTOPH; Thomas ;   et al. | 2019-09-12 |
Method of inhibiting chronification of pain Grant 10,398,657 - Schiene , et al. Sep | 2019-09-03 |
Method of treating psoriatic arthritis, psoriasis, and chronic obstructive pulmonary disease with a novel 2,5-substituted pyrimidines Grant 10,391,099 - Nardi , et al. A | 2019-08-27 |
Transdermal administration of memantine Grant 10,363,228 - Eifler , et al. | 2019-07-30 |
Pharmaceutical composition comprising (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexa- ne-1,1'-pyrano[3,4,b]indo]-4-amine and antidepressants Grant 10,328,055 - Frosch , et al. | 2019-06-25 |
Substituted Pyrrolidine Amides II App 20190185470 - JAKOB; Florian ;   et al. | 2019-06-20 |
Substituted Pyrrolidine Amides I App 20190185455 - JAKOB; Florian ;   et al. | 2019-06-20 |
Process for the preparation of 5-fluorotryptophol Grant 10,323,040 - Pruehs , et al. | 2019-06-18 |
Pharmaceutical Combination App 20190133971 - SCHIENE; Klaus ;   et al. | 2019-05-09 |
Treatment of Vulvodynia App 20190117634 - QUETGLAS; Emilio ;   et al. | 2019-04-25 |
3-((Hetero-)Aryl)-8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives App 20190106429 - Kuehnert; Sven ;   et al. | 2019-04-11 |
8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane Derivatives App 20190100515 - KUEHNERT; Sven ;   et al. | 2019-04-04 |
Substituted azaspiro(4.5)decane derivatives Grant 10,214,520 - Wegert , et al. Feb | 2019-02-26 |
Pharmaceutical combination Grant 10,206,890 - Schiene , et al. Feb | 2019-02-19 |
Tamper-resistant tablet providing immediate drug release Grant 10,201,502 - Schwier , et al. Feb | 2019-02-12 |
Substituted azaspiro(4.5)decane derivatives Grant 10,202,345 - Wegert , et al. Feb | 2019-02-12 |
Substituted pyrimidine compounds Grant 10,189,854 - Nardi , et al. Ja | 2019-01-29 |
3-(carboxymethyl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane Derivatives App 20180282341 - KUEHNERT; Sven ;   et al. | 2018-10-04 |
3-(carboxyethyl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane Derivatives App 20180273491 - KUEHNERT; Sven ;   et al. | 2018-09-27 |
Hot-melt extruded pharmaceutical dosage form Grant 10,080,721 - Barnscheid , et al. September 25, 2 | 2018-09-25 |
Pharmaceutical composition comprising (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexa- ne-1,1'-pyrano-[3,4,b]indol]-4-amine and a propionic acid derivative Grant 10,076,510 - Frosch , et al. September 18, 2 | 2018-09-18 |
Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc Grant 10,064,945 - Barnscheid , et al. September 4, 2 | 2018-09-04 |
Composition for Intravesical Administration for Treating Bladder Pain App 20180243273 - VAN HEMELRIJCK; Carlos | 2018-08-30 |
Use of 1-phenyl-3-dimethylaminopropane Compounds for Treating Rheumatoid Pain App 20180235909 - JAHNEL; Ulrich ;   et al. | 2018-08-23 |
Crystalline Forms of (-)-(1R,2R)-3-(3-dimethylamino-1-ethyl-2-methylpropyl)-phenol hydrochloride App 20180230082 - FISCHER; Andreas ;   et al. | 2018-08-16 |
Prolonged Release Pharmaceutical Composition Containing 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)phenol App 20180221308 - BARTHOLOMAEUS; Johannes ;   et al. | 2018-08-09 |
Treatment of Irritable Bowel Syndrome App 20180200205 - SCHIENE; Klaus ;   et al. | 2018-07-19 |
3-((Hetero-)Aryl)-8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives App 20180201616 - Kuehnert; Sven ;   et al. | 2018-07-19 |
Cebranopadol for treating pain in subjects with impaired hepatic and/or impaired renal function Grant 10,022,353 - Kleideiter , et al. July 17, 2 | 2018-07-17 |
Use of tapentadol for inhibiting and/or treating depression and anxiety Grant 9,980,927 - Steigerwald , et al. May 29, 2 | 2018-05-29 |
Semisolid Aqueous Pharmaceutical Composition Containing Tapentadol App 20180133174 - REINHOLD; Ulrich ;   et al. | 2018-05-17 |
Stable Formulation for Parenteral Administration of Tapentadol App 20180125800 - SCHILLER; Marc ;   et al. | 2018-05-10 |
Pharmaceutical Composition Comprising (1r,4r)-6'-fluoro-N, N-dimethyl-4-phenyl-4',9' -dihydro-3'H-spiro[cyclohexane-1,1' -pyrano[3,4,b]indol]-4-amine and Paracetamol or Propacetamol App 20180092867 - FROSCH; Stefanie ;   et al. | 2018-04-05 |
Stable Formulation for Parenteral Administration of Tapentadol App 20180085328 - ELLERMANN; Angelika ;   et al. | 2018-03-29 |
Crystalline Forms of (-)-(1R,2R)-3-(3-dimethylamino-1-ethyl-2-methylpropyl)-phenolhydrochlorid- e App 20180029976 - FISCHER; Andreas ;   et al. | 2018-02-01 |
Cebranopadol for Treating Pain in Subjects with Impaired Hepatic And/Or Impaired Renal Function App 20180008576 - KLEIDEITER; Elke ;   et al. | 2018-01-11 |
Process or preparing spirocyclic cyclohexane compounds, compositions containing such compounds and method of using such compounds Grant 9,862,719 - Hinze , et al. January 9, 2 | 2018-01-09 |
Pharmaceutical composition comprising (1r,4r)-6'-fluoro-N,N-di methyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano-[3,4,b]in- dol]-4-amine and a salicylic acid component Grant 9,855,286 - Frosch , et al. January 2, 2 | 2018-01-02 |
Process for preparing substituted 3-(1-amino-2-methylpentane-3-yl)phenyl compounds Grant 9,850,198 - Buschmann , et al. December 26, 2 | 2017-12-26 |
Pharmaceutical Combination App 20170333369 - SCHIENE; Klaus ;   et al. | 2017-11-23 |
Use of 1-phenyl-3-dimethylaminopropane Compounds for Treating Rheumatoid Pain App 20170326079 - JAHNEL; Ulrich ;   et al. | 2017-11-16 |
Cis-tetrahydro-spiro(cyclohexane-1,1?-pyrido[3,4-b]indole)-4-amine Compounds App 20170313703 - LINZ; Klaus ;   et al. | 2017-11-02 |
Fluoromethyl-substituted pyrrole carboxamides iv Grant 9,802,921 - Reich , et al. October 31, 2 | 2017-10-31 |
Tapentadol Compositions App 20170216212 - SESHA; RAMESH | 2017-08-03 |
Treatment of Irritable Bowel Syndrome App 20170216226 - SCHIENE; Klaus ;   et al. | 2017-08-03 |
Substituted Azaspiro(4.5)Decane Derivatives App 20170210734 - WEGERT; Anita ;   et al. | 2017-07-27 |
3-((Hetero-)Aryl)-8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives App 20170197970 - KUEHNERT; Sven ;   et al. | 2017-07-13 |
3-((Hetero-)Aryl)-Alkyl-8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives App 20170197947 - KUEHNERT; Sven ;   et al. | 2017-07-13 |
3-(Carboxyethyl)-8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives App 20170197919 - KUEHNERT; Sven ;   et al. | 2017-07-13 |
3-(Carboxymethyl)-8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives App 20170197971 - KUEHNERT; Sven ;   et al. | 2017-07-13 |
8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives App 20170197949 - KUEHNERT; Sven ;   et al. | 2017-07-13 |
Use of Tapentadol for Inhibiting and/or Treating Depression and Anxiety App 20170196822 - STEIGERWALD; Ilona ;   et al. | 2017-07-13 |
Crystalline Forms of (-)-(1R,2R)-3-(3-dimethylamino-1-ethyl-2-methylpropyl)-phenol hydrochloride App 20170166515 - FISCHER; Andreas ;   et al. | 2017-06-15 |
Pharmaceutical Patch for Transdermal Administration of Tapentadol App 20170128388 - FRIEDRICH; Ingo ;   et al. | 2017-05-11 |
And potent tapentadol dosage forms Grant 9,642,801 - Sesha May 9, 2 | 2017-05-09 |
Tamper resistant dosage form comprising an anionic polymer Grant 9,636,303 - Barnscheid , et al. May 2, 2 | 2017-05-02 |
Pharmaceutical composition comprising (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexa- ne-1,1'-pyrano[3,4,b]indol]-4-amine and a gabapentinoid Grant 9,629,825 - Frosch , et al. April 25, 2 | 2017-04-25 |
Substituted phenylureas and phenylamides as vanilloid receptor ligands Grant 9,624,209 - Frank-Foltyn , et al. April 18, 2 | 2017-04-18 |
Prolonged Release Pharmaceutical Composition Containing 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)phenol App 20170087103 - BARTHOLOMAEUS; JOHANNES ;   et al. | 2017-03-30 |
Titration of Tapentadol App 20170079938 - LANGE; Claudia ;   et al. | 2017-03-23 |
Pharmaceutical Composition Comprising (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexa- ne-1,1'-pyrano[3,4,b]indo]-4-amine and Antidepressants App 20170065560 - Frosch; Stefanie ;   et al. | 2017-03-09 |
Device and Formulation for Topical Treatment of Pain Affecting the Vulvar Area of the Female Human Genital Organ App 20170056635 - DIMINO; Andre ;   et al. | 2017-03-02 |
Preparation of a powdery pharmaceutical composition by means of an extruder Grant 9,579,285 - Haupts February 28, 2 | 2017-02-28 |
Treatment of Irritable Bowel Syndrome App 20170042836 - SCHIENE; Klaus ;   et al. | 2017-02-16 |
Abuse-proofed dosage forms App 20170027886 - BARTHOLOMAUS; Johannes ;   et al. | 2017-02-02 |
2,5-substituted pyrimidines Grant 9,546,158 - Nardi , et al. January 17, 2 | 2017-01-17 |
Substituted pyrimidine compounds Grant 9,540,349 - Nardi , et al. January 10, 2 | 2017-01-10 |
Process for the Preparation of 5-Fluorotryptophol App 20160362417 - PRUEHS; Stefan ;   et al. | 2016-12-15 |
Pharmaceutical Dosage Forms Comprising 6'-Fluoro-(N-Methyl- or N,N-Dimethyl-)-4-Phenyl-4',9'-Dihydro-3'H-Spiro[Cyclohexane-1,1'-Pyrano[3- ,4,b]Indol]-4-Amine App 20160361294 - GRUENING; Nadja ;   et al. | 2016-12-15 |
Pharmaceutical Combination App 20160361276 - SCHIENE; Klaus ;   et al. | 2016-12-15 |
Abuse-proofed Dosage Form App 20160361308 - BARTHOLOMAUS; Johannes ;   et al. | 2016-12-15 |
Method of Inhibiting Chronification of Pain App 20160354324 - SCHIENE; Klaus ;   et al. | 2016-12-08 |
Use of 1-phenyl-3-dimethylaminopropane Compounds for Treating Rheumatoid Pain App 20160346228 - JAHNEL; Ulrich ;   et al. | 2016-12-01 |
Semisolid Aqueous Pharmaceutical Composition Containing Tapentadol App 20160346229 - REINHOLD; Ulrich ;   et al. | 2016-12-01 |
Combination of Selected Analgesics and Cox-II Inhibitors App 20160279150 - SCHIENE; Klaus ;   et al. | 2016-09-29 |
Stable Formulation for Parenteral Administration of Tapentadol App 20160279078 - SCHILLER; Marc ;   et al. | 2016-09-29 |
Spirocyclic Cyclohexane Compounds Useful To Treat Substance Dependency App 20160271107 - FRIDERICHS; Elmar ;   et al. | 2016-09-22 |
Semisolid aqueous pharmaceutical composition containing tapentadol Grant 9,446,008 - Reinhold , et al. September 20, 2 | 2016-09-20 |
Process for Preparing Substituted 3-(1-amino-2-methylpentane-3-yl)phenyl Compounds App 20160257640 - BUSCHMANN; Helmut Heinrich ;   et al. | 2016-09-08 |
Aqueous Pharmaceutical Formulation of Tapentadol for Oral Administration App 20160220516 - REINHOLD; Ulrich ;   et al. | 2016-08-04 |
Substituted 4-aminocyclohexane derivatives Grant 9,403,767 - Nolte , et al. August 2, 2 | 2016-08-02 |
Pharmaceutical Composition Comprising (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexa- ne-1,1'-pyrano-[3,4,b]indol]-4-amine and a Propionic Acid Derivative App 20160199349 - FROSCH; Stefanie ;   et al. | 2016-07-14 |
Process for preparing substituted 3-(1-amino-2-methylpentane-3-yl)phenyl compounds Grant 9,388,119 - Buschmann , et al. July 12, 2 | 2016-07-12 |
Pharmaceutical composition comprising (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexa- ne-1,1'-pyrano[3,4,b]indol]-4-amine and a gabapentinoid App 20160193183 - FROSCH; Stefanie ;   et al. | 2016-07-07 |
Cis-tetrahydro-spiro(cyclohexane-1, 1' -pyrido[3,4-b]indole)-4-amine Compounds App 20160159787 - LINZ; Klaus ;   et al. | 2016-06-09 |
Prolonged Release Pharmaceutical Composition Containing 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)phenol App 20160151309 - BARTHOLOMAEUS; Johannes ;   et al. | 2016-06-02 |
Pharmaceutical composition comprising (1r,4r)-6'-fluoro-N, N-dimethyl-4-phenyl-4,9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano[3,4,b]- indol]-4-amine and an anticonvulsant Grant 9,345,689 - Frosch , et al. May 24, 2 | 2016-05-24 |
Pharmaceutical Combination App 20160128952 - BLOMS-FUNKE; Petra ;   et al. | 2016-05-12 |
Crystalline Forms of (-)-(1R,2R)-3-(3-dimethylamino-1-ethyl-2-methylpropyl)-phenol hydrochloride App 20160122287 - FISCHER; Andreas ;   et al. | 2016-05-05 |
Pharmaceutical composition comprising (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4'9'-dihydro-3'H-spiro[cyclohexan- e-1,1'-pyrano[3,4,b]indol]-4-amine and a gabapentinoid Grant 9,320,725 - Frosch , et al. April 26, 2 | 2016-04-26 |
Pharmaceutical composition comprising (1r,4r)-6'-flouro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexa- ne-1,1'-pyrano-[3,4,b]indol]-4-amine and a propionic acid derivative Grant 9,320,729 - Frosch , et al. April 26, 2 | 2016-04-26 |
Parenteral Administration of Tapentadol App 20160106688 - CHRISTOPH; Thomas ;   et al. | 2016-04-21 |
2,5-substituted pyrimidines Grant 9,315,490 - Konetzki , et al. April 19, 2 | 2016-04-19 |
Pharmaceutical composition comprising (1 r,4r) -6'-fluoro-N ,N-dimethyl-4-phenyl-4',9'-d ihydro-3'H-spiro[cyclohexane-1,1'-pyrano-[3,4,b]indol]-4-amine and an oxicam Grant 9,308,196 - Frosch , et al. April 12, 2 | 2016-04-12 |
Crystalline cis-(E)-4-(3-fluorophenyl)-2',3',4',9'-tetrahydro-N,N-dimethyl-2'-(1-oxo-- 3-phenyl-2-propenyl)-spiro[cyclohexane-1,1'[1H] Grant 9,296,749 - Gruss March 29, 2 | 2016-03-29 |
Pharmaceutical dosage forms comprising 6'-fluoro-(N-methyl- or N,N-dimethyl-)-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano[3- ,4,b]indol]-4-amine Grant 9,289,416 - Gruening , et al. March 22, 2 | 2016-03-22 |
Titration of Tapentadol App 20160074342 - LANGE; Claudia ;   et al. | 2016-03-17 |
Pharmaceutical Combination App 20160045459 - SCHIENE; Klaus ;   et al. | 2016-02-18 |
Pharmaceutical Combination App 20160045458 - SCHIENE; Klaus ;   et al. | 2016-02-18 |
Substituted Azaspiro(4.5)Decane Derivatives App 20160016903 - WEGERT; Anita ;   et al. | 2016-01-21 |
Crush resistant delayed-release dosage forms App 20150374630 - ARKENAU MARIC; Elisabeth ;   et al. | 2015-12-31 |
Mixed ORL1/mu-agonists for the Treatment of Pain App 20150342929 - LINZ; Klaus ;   et al. | 2015-12-03 |
Process for Preparing Spirocyclic Cyclohexane Compounds, Compositions Containing Such Compounds and Method of Using Such Compounds App 20150322080 - HINZE; Claudia ;   et al. | 2015-11-12 |
Salts or co-crystals of 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol Grant 9,133,142 - Gruss , et al. September 15, 2 | 2015-09-15 |
Process for preparing spirocyclic cyclohexane compounds, compositions containing such compounds and method of using such compounds Grant 9,120,797 - Hinze , et al. September 1, 2 | 2015-09-01 |
Substituted phenylureas and phenylamides as vanilloid receptor ligands Grant 9,120,756 - Frank , et al. September 1, 2 | 2015-09-01 |
Substituted 4-aminobenzamides as KCNQ2/3 modulators Grant 9,108,936 - Bahrenberg , et al. August 18, 2 | 2015-08-18 |
Pyrazolyl-based carboxamides II Grant 9,078,899 - Nordhoff , et al. July 14, 2 | 2015-07-14 |
Substituted 2-oxy-quinoline-3-carboxamides as KCNQ2/3 modulators Grant 9,073,862 - Kuhnert , et al. July 7, 2 | 2015-07-07 |
Process For The Production Of An Abuse-proofed Solid Dosage Form App 20150182464 - ARKENAU MARIC; Elisabeth ;   et al. | 2015-07-02 |
Process For The Production Of An Abuse-proofed Solid Dosage Form App 20150182465 - Arkenau Maric; Elisabeth ;   et al. | 2015-07-02 |
Plaster causing reduced skin irritation Grant 9,066,888 - Kugelmann , et al. June 30, 2 | 2015-06-30 |
Electric-Field Assisted Administration of Tapentadol App 20150148735 - FRIEDRICH; Ingo ;   et al. | 2015-05-28 |
Pharmaceutical Patch for Transdermal Administration of Tapentadol App 20150148759 - FRIEDRICH; Ingo ;   et al. | 2015-05-28 |
Substituted bicyclic aromatic carboxamide and urea compounds as vanilloid receptor ligands Grant 9,029,378 - Frank , et al. May 12, 2 | 2015-05-12 |
Pharmaceutical Dosage Forms Comprising 6'-Fluoro-(N-Methyl- or N,N-Dimethyl-)-4-Phenyl-4',9'-Dihydro-3'H-Spiro[Cyclohexane-1,1'-Pyrano[3- ,4,b]Indol]-4-Amine App 20150111939 - GRUENING; Nadja ;   et al. | 2015-04-23 |
Substituted Phenylureas and Phenylamides as Vanilloid Receptor Ligands App 20150099728 - FRANK; Robert ;   et al. | 2015-04-09 |
Combination of selected opioids with muscarine antagonists for treating urinary incontinence Grant 8,946,290 - Christoph February 3, 2 | 2015-02-03 |
Substituted phenylureas and phenylamides as vanilloid receptor ligands Grant 8,946,204 - Frank , et al. February 3, 2 | 2015-02-03 |
Aryl or N-heteroaryl substituted methanesulfonamide derivatives as vanilloid receptor ligands Grant 8,937,092 - Frank , et al. January 20, 2 | 2015-01-20 |
Use of Tapentadol for Inhibiting and/or Treating Depression and Anxiety App 20150018426 - STEIGERWALD; Ilona ;   et al. | 2015-01-15 |
Substituted Phenylureas and Phenylamides as Vanilloid Receptor Ligands App 20150011592 - FRANK; Robert ;   et al. | 2015-01-08 |
Pharmaceutical composition comprising (1r,4r) -6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'- -pyrano[3,4,b]indol]-4-amine and a NSAR Grant 8,912,226 - Frosch , et al. December 16, 2 | 2014-12-16 |
Solid forms of (1r,4r)-6'-fluoro-(N, N-dimethyl)-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano-[3,4- ,b]indol]-4-amine and sulfuric acid Grant 8,912,343 - Gruss , et al. December 16, 2 | 2014-12-16 |
Star distributor Grant 8,894,904 - Schateikis , et al. November 25, 2 | 2014-11-25 |
Solid forms of (1r,4r)-6'-fluoro-N,N-dimethy1-4-phenyl-4',9'-dihydro-3' H-spiro-[cyclohexane-1,1'-pyrano-[3,4,b]indol]-4-amine hydrochloride Grant 8,895,604 - Gruss , et al. November 25, 2 | 2014-11-25 |
Intrathecal or epidural administration of 3-[(1S,25)-3-(dimethylamino)-1-ethyl-2-methylpropyl]phenol Grant 8,895,623 - Bloms-Funke , et al. November 25, 2 | 2014-11-25 |
Pharmaceutical Combination App 20140309311 - SCHIENE; Klaus ;   et al. | 2014-10-16 |
Spirocyclic Cyclohexane Compounds Useful To Treat Substance Dependency App 20140303125 - FRIDERICHS; Elmar ;   et al. | 2014-10-09 |
Crystalline Forms of (-)-(1R,2R)-3-(3-dimethylamino-1-ethyl-2-methylpropyl)-phenol hydrochloride App 20140296346 - FISCHER; Andreas ;   et al. | 2014-10-02 |
Pharmaceutical combination Grant 8,846,765 - Schiene , et al. September 30, 2 | 2014-09-30 |
Crystalline cis-(E)-4-(3-Fluorophenyl)-2',3',4',9'-tetrahydro-N,N-dimethyl-2'-(1-oxo-- 3-phenyl-2-propenyl)-spiro[cyclohexane-1,1'[1H]-pyrido[3,4-b]indol]-4-amin- e App 20140288307 - GRUSS; Michael | 2014-09-25 |
Tapentadol Compositions App 20140242169 - SESHA; RAMESH | 2014-08-28 |
Process for preparing a substituted dimethyl-(3-arylbutyl)amine compound by homogeneous catalysis Grant 8,791,300 - Hell , et al. July 29, 2 | 2014-07-29 |
Vanilloid receptor ligands, pharmaceutical compositions containing them, process for making them, and use thereof for treating pain and other conditions Grant 8,791,268 - Frank , et al. July 29, 2 | 2014-07-29 |
Vanilloid receptor ligands, pharmaceutical compositions containing them, process for making them, and use thereof to treat pain and other conditions Grant 8,785,474 - Frank , et al. July 22, 2 | 2014-07-22 |
Process for the preparation of (1r,4r)-6'-fluoro-(N,N-dimethyl- and N-methyl)-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano-[3,4,b- ]indol]-4-amine Grant 8,779,160 - Pruehs , et al. July 15, 2 | 2014-07-15 |
Substituted spiro compounds and their use for producing pain-relief medicaments Grant 8,772,307 - Frank , et al. July 8, 2 | 2014-07-08 |
Amine substituted methanesulfonamide derivatives as vanilloid receptor ligands Grant 8,765,733 - Frank , et al. July 1, 2 | 2014-07-01 |
Crystalline (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexa- ne-1,1'-pyrano[3,4,b]indol]-4-amine Grant 8,765,800 - Gruss , et al. July 1, 2 | 2014-07-01 |
Novel Vanilloid Receptor Ligands and Use Thereof for the Production of Pharmaceutical Preparations App 20140179686 - LEE; Jeewoo ;   et al. | 2014-06-26 |
Abuse-proofed Dosage Form App 20140170079 - ARKENAU MARIC; Elisabeth ;   et al. | 2014-06-19 |
Dosage form with improved release of cefuroximaxetil Grant 8,747,900 - Ziegler , et al. June 10, 2 | 2014-06-10 |
Vanilloid receptor ligands, pharmaceutical compositions containing them, process for making them and use thereof for treating pain and other conditions Grant 8,735,426 - Frank , et al. May 27, 2 | 2014-05-27 |
Substituted Phenylureas and Phenylamides as Vanilloid Receptor Ligands App 20140142143 - FRANK; Robert ;   et al. | 2014-05-22 |
Dosage form with impeded abuse Grant 8,722,086 - May 13, 2 | 2014-05-13 |
Vanilloid receptor ligands and use thereof for the production of pharmaceutical preparations Grant 8,710,233 - Lee , et al. April 29, 2 | 2014-04-29 |
Process For The Production Of An Abuse-proofed Solid Dosage Form App 20140113926 - Maric; Elisabeth Arkenau ;   et al. | 2014-04-24 |
Crush resistant delayed-release dosage forms App 20140112984 - ARKENAU-MARIC; Elisabeth ;   et al. | 2014-04-24 |
Abuse-proofed Oral Dosage Form App 20140112989 - Bartholomaus; Johannes ;   et al. | 2014-04-24 |
Process for the dehydration of substituted 4-dimethylamino-2-aryl-butan-2-ol compounds and process for the preparation of substituted dimethyl-(3-aryl-butyl)-amine compounds by heterogeneous catalysis Grant 8,704,002 - Jagusch , et al. April 22, 2 | 2014-04-22 |
Abuse-proofed Dosage Form App 20140105830 - BARTHOLOMAUS; Johannes ;   et al. | 2014-04-17 |
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Abuse-proofed dosage forms App 20140080915 - Bartholomaus; Johannes ;   et al. | 2014-03-20 |
Abuse-proofed dosage forms App 20140080858 - BARTHOLOMAUS; Johannes ;   et al. | 2014-03-20 |
Crush resistant delayed-release dosage forms App 20140079780 - ARKENAU MARIC; Elisabeth ;   et al. | 2014-03-20 |
Method for synthesizing substituted aminocyclohexanone compounds Grant 8,658,827 - Pruehs , et al. February 25, 2 | 2014-02-25 |
Substituted 2-oxo- and 2-thioxo-dihydroquinoline-3-carboxamides as KCNQ2/3 modulators Grant 8,653,102 - Kuhnert , et al. February 18, 2 | 2014-02-18 |
Substituted 2-oxy-quinoline-3-carboxamides as KCNQ2/3 modulators Grant 8,653,101 - Kuhnert , et al. February 18, 2 | 2014-02-18 |
4-(methyl sulfonyl amino) phenyl analogues as vanilloid antagonist showing excellent analgesic activity and the pharmaceutical compositions comprising the same Grant 8,642,657 - Lee , et al. February 4, 2 | 2014-02-04 |
Vanilloid receptor ligands, pharmaceutical compositions containing them, process for making them, and use thereof for treating pain and other conditions Grant 8,642,775 - Frank , et al. February 4, 2 | 2014-02-04 |
Vanilloid receptor ligand compounds, pharmaceutical compositions containing them, a method of producing them and the use thereof to treat pain and various other conditions Grant 8,642,623 - Frank , et al. February 4, 2 | 2014-02-04 |
Crystalline Forms of (-)-(1R, 2R)-3-(3-dimethylamino-1-ethyl-2-methylpropyl)-phenol hydrochloride App 20140011886 - Fischer; Andreas ;   et al. | 2014-01-09 |
Crystalline (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexa- ne-1,1'-pyrano[3,4,b]indol]-4-amine Grant 8,618,156 - Gruss , et al. December 31, 2 | 2013-12-31 |
Method of treating pain caused by inflammation Grant 8,618,177 - Schiene , et al. December 31, 2 | 2013-12-31 |
Substituted 1-oxo-dihydroisoquinoline-3-carboxamides as KCNQ2/3 modulators Grant 08618129 - | 2013-12-31 |
Substituted 1-oxo-dihydroisoquinoline-3-carboxamides as KCNQ2/3 modulators Grant 8,618,129 - Kuhnert , et al. December 31, 2 | 2013-12-31 |
Crystalline (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano[3,4,b]indol]-4-amine Grant 08618156 - | 2013-12-31 |
Method of treating pain caused by inflammation Grant 08618177 - | 2013-12-31 |
Crystalline (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexa- ne-1,1'-pyrano[3,4,b]indol]-4-amine Grant 8,614,245 - Gruss , et al. December 24, 2 | 2013-12-24 |
Process for Preparing Substituted 3-(1-amino-2-methylpentane-3-yl)phenyl Compounds App 20130338399 - BUSCHMANN; Helmut Heinrich ;   et al. | 2013-12-19 |
Pharmaceutical Composition Comprising (1r,4r)-6'-flouro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexa- ne-1,1'-pyrano-[3,4,b]indol]-4-amine and a propionic acid derivative App 20130324581 - FROSCH; Stefanie ;   et al. | 2013-12-05 |
Pharmaceutical Composition Comprising (1r,4r)-6'-fluoro-N, N-dimethyl-4-phenyl-4,9' -dihydro-3'H-spiro[cyclohexane-1,1' -pyrano[3,4,b]indol]-4-amine and an Anticonvulsant App 20130317009 - FROSCH; Stefanie ;   et al. | 2013-11-28 |
Pharmaceutical Composition Comprising (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexa- ne-1,1'-pyrano-[3,4,b]indol]-4-amine and a Salicylic Acid Component App 20130317076 - FROSCH; Stefanie ;   et al. | 2013-11-28 |
Pharmaceutical Composition Comprising (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexa- ne-1,1'-pyrano[3,4,b]indol]-4-amine and a NSAR App 20130317075 - FROSCH; Stefanie ;   et al. | 2013-11-28 |
Substituted phenylureas and phenylamides as vanilloid receptor ligands Grant 8,592,471 - Frank , et al. November 26, 2 | 2013-11-26 |
Pharmaceutical composition comprising (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4'9'-dihydro-3'H-spiro[cyclohexan- e-1,1'-pyrano[3,4,b]indol]-4-amine and a gabapentinoid App 20130310434 - FROSCH; Stefanie ;   et al. | 2013-11-21 |
Pharmaceutical composition comprising (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexa- ne-1,1'-pyrano-[3,4,b]indol]-4-amine and an oxicam App 20130310371 - FROSCH; Stefanie ;   et al. | 2013-11-21 |
Pharmaceutical Composition Comprising (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexa- ne-1,1'-pyrano[3,4,b]indol]-4-amine and Antidepressants App 20130310385 - FROSCH; Stefanie ;   et al. | 2013-11-21 |
Pharmaceutical Composition Comprising (1r,4r)-6'-fluoro-N, N-dimethyl-4-phenyl-4,9' -dihydro-3'H-spiro[cyclohexane-1,1' -pyrano[3,4,b]indol]-4-amine and Paracetamol or Propacetamol App 20130310435 - FROSCH; Stefanie ;   et al. | 2013-11-21 |
Substituted sulfonamide compounds Grant 8,580,965 - Oberboersch , et al. November 12, 2 | 2013-11-12 |
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Substituted 4-aminobenzamides As Kcnq2/3 Modulators App 20130281452 - BAHRENBERG; Gregor ;   et al. | 2013-10-24 |
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Substituted sulfonamide compounds Grant 8,541,573 - Oberboersch , et al. September 24, 2 | 2013-09-24 |
HCl Polymorphs of 3-((2-(Dimethylamino)methyl(cyclohex-1-yl))phenol App 20130245125 - GRUSS; Michael ;   et al. | 2013-09-19 |
Use of 1 phenyl-3-dimethylamino-propane compounds for treating neuropathic pain Grant 8,536,130 - Christoph , et al. September 17, 2 | 2013-09-17 |
Prolonged Release Pharmaceutical Composition Containing 3-(3-Dimethylamino-1-Ethyl-2-Methyl-Propyl)Phenol App 20130237608 - BARTHOLOMAEUS; Johannes ;   et al. | 2013-09-12 |
Crystalline (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexa- ne-1,1'-pyrano[3,4,b]indol]-4-amine App 20130231381 - GRUSS; Michael ;   et al. | 2013-09-05 |
Substituted Spiro-Amide Compounds App 20130231327 - SCHUNK; Stefan ;   et al. | 2013-09-05 |
Pharmaceutical patch for transdermal administration of (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexa- ne-1,1'-pyrano[3,4-b]indol]-4-amine App 20130211351 - FUHRHERR; Richard ;   et al. | 2013-08-15 |
(1r,4r)-6'-Fluoro-(N-methyl- or N,N-dimethyl-)-4-phenyl-4',9'-dihydro-3'H-spiro-[cyclohexane-1,1'-pyrano[- 3,4,b]indol]-4-amine for Treating Fibromyalgia and Chronic Fatigue Syndrome App 20130202701 - FROSCH; Stefanie ;   et al. | 2013-08-08 |
Pharmaceutical Combination App 20130190333 - SCHIENE; Klaus ;   et al. | 2013-07-25 |
Substituted indole compounds Grant 8,492,559 - Schunk , et al. July 23, 2 | 2013-07-23 |
Substituted 2-amino-quinoline-3-carboxamides as KCNQ2/3 modulators Grant 8,470,852 - Kuhnert , et al. June 25, 2 | 2013-06-25 |
Process for the preparation of (1r,4r)-6'-fluoro-(N,N-dimethyl- and N-methyl)-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano-[3,4,b- ]indol]-4-amine App 20130150590 - PRUEHS; Stefan ;   et al. | 2013-06-13 |
Solid forms of (1 r,4r)-6' -fluoro-(N, N-dimethyl)-4-phenyl-4' ,9'-dihydro-3'H-spiro[cyclohexane-1,1 '-pyrano-[3,4,b]indol]-4-amine and sulfuric acid App 20130150589 - GRUSS; Michael ;   et al. | 2013-06-13 |
Solid forms of (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3' H-spiro-[cyclohexane-1,1'-pyrano-[3,4,b]indol]-4-amine hydrochloride App 20130150420 - GRUSS; Michael ;   et al. | 2013-06-13 |
Substituted spiro-amide compounds Grant 8,455,475 - Schunk , et al. June 4, 2 | 2013-06-04 |
Tamper-resistant Oral Pharmaceutical Dosage Form Comprising Opioid Antagonist And/or Aversive Agent, Polyalkylene Oxide And Anionic Polymer App 20130129826 - GEI LER; Anja ;   et al. | 2013-05-23 |
Substituted quinoline-3-carboxamides as KCNQ2/3 modulators Grant 8,445,512 - Kuhnert , et al. May 21, 2 | 2013-05-21 |
Crystalline (1r, 4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1- ,1'-pyrano[3,4,b]indol]-4-amine App 20130123324 - Gruss; Michael ;   et al. | 2013-05-16 |
Treatment of Irritable Bowel Syndrome App 20130116334 - SCHIENE; Klaus ;   et al. | 2013-05-09 |
Substituted sulfonamide compounds Grant 8,435,978 - Oberboersch , et al. May 7, 2 | 2013-05-07 |
Combination of Selected Analgesics and Cox-II Inhibitors App 20130109733 - SCHIENE; Klaus ;   et al. | 2013-05-02 |
Combination of selected analgesics and COX-II inhibitors Grant 8,420,691 - Schiene , et al. April 16, 2 | 2013-04-16 |
Intrathecal or Epidural Administration of 3-[(1S,2S)-3-(Dimethylamino)-1-Ethyl-2-Methylpropyl]Phenol App 20130085184 - BLOMS-FUNKE; Petra ;   et al. | 2013-04-04 |
Amine Substituted Methanesulfonamide Derivatives as Vanilloid Receptor Ligands App 20130079320 - FRANK; Robert ;   et al. | 2013-03-28 |
Substituted Methanesulfonamide Derivatives as Vanilloid Receptor Ligands App 20130079373 - FRANK; Robert ;   et al. | 2013-03-28 |
Aryl or N-heteroaryl Substituted Methanesulfonamide Derivatives as Vanilloid Receptor Ligands App 20130079377 - Frank; Robert ;   et al. | 2013-03-28 |
Spirocyclic cyclohexane compounds Grant 8,404,740 - Schunk , et al. March 26, 2 | 2013-03-26 |
Method of inhibiting inflammatory pain Grant 8,404,749 - Schiene , et al. March 26, 2 | 2013-03-26 |
Substituted 2-mercaptoquinoline-3-carboxamides as KCNQ2/3 modulators Grant 8,399,673 - Kuhnert , et al. March 19, 2 | 2013-03-19 |
Spirocyclic azaindole derivatives Grant 8,399,503 - Zemolka , et al. March 19, 2 | 2013-03-19 |
Process for the Dehydration of Substituted 4-Dimethylamino-2-aryl-butan-2-ol Compounds and Process for the Preparation of Substituted Dimethyl-(3-aryl-butyl)- Amine Compounds by Heterogeneous Catalysis App 20130060065 - JAGUSCH; Utz-Peter ;   et al. | 2013-03-07 |
Pharmaceutical dosage form Grant 8,383,152 - Jans , et al. February 26, 2 | 2013-02-26 |
Method and device for discarding incomplete sets of caps Grant 8,373,080 - Schateikis , et al. February 12, 2 | 2013-02-12 |
Substituted 4-(1.2,3,4-tetrahydroisoquinolin-2-yl)-4-oxobutyric acid amide as KCNQ2/3 modulators Grant 8,367,700 - Kuhnert , et al. February 5, 2 | 2013-02-05 |
Substituted Bicyclic Aromatic Carboxamide and Urea Compounds as Vanilloid Receptor Ligands App 20130029995 - FRANK; Robert ;   et al. | 2013-01-31 |
Substituted Heterocyclic Aza Compounds App 20130029961 - FRANK; Robert ;   et al. | 2013-01-31 |
Substituted Heteroaromatic Pyrazole-Containing Carboxamide and Urea Compounds as Vanilloid Receptor Ligands App 20130029962 - FRANK; Robert ;   et al. | 2013-01-31 |
Fast release dosage forms for antibiotics Grant 8,361,506 - Ziegler , et al. January 29, 2 | 2013-01-29 |
Aqueous Pharmaceutical Formulation of Tapentadol for Oral Administration App 20130022670 - REINHOLD; Ulrich ;   et al. | 2013-01-24 |
Substituted cyclohexyldiamines Grant 8,357,705 - Zemolka , et al. January 22, 2 | 2013-01-22 |
Spiro group-containing amide compounds having bradykinin 1 receptor (B1R) activity Grant 8,357,717 - Schunk , et al. January 22, 2 | 2013-01-22 |
Crystalline (1r,4r)-6'-fluoro-n,n-dimethyl-4-phenyl-4',9'-dihydro-3'h-spiro[cyclohexa- Ne-1,1'-pyrano[3,4,b]indol]-4-amine App 20130012563 - Gruss; Michael ;   et al. | 2013-01-10 |
Substituted aromatic carboxamide and urea derivatives as vanilloid receptor ligands Grant 8,334,315 - Frank , et al. December 18, 2 | 2012-12-18 |
Treatment of Pain Associated with Trigeminal Neuralgia App 20120309840 - CHRISTOPH; Thomas ;   et al. | 2012-12-06 |
Method of Inhibiting Chronification of Pain App 20120309841 - Schiene; Klaus ;   et al. | 2012-12-06 |
Process for the production of an abuse-proofed solid dosage form Grant 8,323,889 - Arkenau-Maric , et al. December 4, 2 | 2012-12-04 |
Vanilloid Receptor Ligand Compounds, Pharmaceutical Compositions Containing Them, a Method of Producing Them and the Use Thereof to Treat Pain and Various Other Conditions App 20120302602 - Frank; Robert ;   et al. | 2012-11-29 |
Crystalline Forms of (-)-(1R,2R)-3-(3-dimethylamino-1-ethyl-2-methylpropyl)-phenol Hydrochloride App 20120302643 - FISCHER; Andreas ;   et al. | 2012-11-29 |
Compounds involving mGluR5 receptor regulation and methods of making the compounds Grant 8,318,774 - Haurand , et al. November 27, 2 | 2012-11-27 |
Crystalline forms of (1RS,3RS,6RS)-6-dimethylaminomethyl-1-(3-methoxyphenyl)cyclohexane-1,3-di- ol hydrochloride Grant 8,309,610 - Gruss , et al. November 13, 2 | 2012-11-13 |
Use of Tapentadol for Inhibiting and/or Treating Depression and Anxiety App 20120277319 - STEIGERWALD; Ilona ;   et al. | 2012-11-01 |
Hydroxymethylcyclohexylamines Grant 8,288,406 - Frormann , et al. October 16, 2 | 2012-10-16 |
Substituted tetrahydroimidazopyridine compounds and the use thereof in the treatment of pain and other conditions Grant 8,288,424 - Merla , et al. October 16, 2 | 2012-10-16 |
Substituted spiroamine compounds Grant 8,278,319 - Reich , et al. October 2, 2 | 2012-10-02 |
Saturated and unsaturated 3-pyridyl-benzocycloalkylmethyl-amines for use in treating pain, depression and/or anxiety Grant 8,278,338 - Sundermann , et al. October 2, 2 | 2012-10-02 |
Substituted pyrimidine and triazine compounds Grant 8,269,000 - Schunk , et al. September 18, 2 | 2012-09-18 |
Substituted sulfonamide compounds Grant 8,268,814 - Reich , et al. September 18, 2 | 2012-09-18 |
Preparation of 3-[(1R,2R)-3-(dimethylamino)-1ethyl-2-methylpropyl]phenol Grant 8,263,809 - Hell September 11, 2 | 2012-09-11 |
Substituted sulfonamide compounds Grant 8,263,598 - Merla , et al. September 11, 2 | 2012-09-11 |
Vanilloid receptor ligand compounds, pharmaceutical compositions containing them, a method of producing them and the use thereof to treat pain and various other conditions Grant 8,252,816 - Frank , et al. August 28, 2 | 2012-08-28 |
Substituted N-(2-mercaptopyridin-3-yl)amides as KCNQ2/3 modulators Grant 8,247,573 - Kuhnert , et al. August 21, 2 | 2012-08-21 |
Substituted benzimidazoles, benzothiazoles and benzoxazoles Grant 8,232,288 - Schunk , et al. July 31, 2 | 2012-07-31 |
Substituted cyclic urea derivatives and the use thereof as vanilloid receptor 1 modulators Grant 8,207,182 - Frank , et al. June 26, 2 | 2012-06-26 |
Substituted 3-amino-2-mercaptoquinolines as KCNQ2/3 modulators Grant 8,207,342 - Kuhnert , et al. June 26, 2 | 2012-06-26 |
Substituted nicotinamides as KCNQ2/3 modulators Grant 8,178,684 - Kuhnert , et al. May 15, 2 | 2012-05-15 |
Substituted sulfonamide compounds having bradykinin 1 receptor activity and use thereof as medicaments Grant 8,178,535 - Merla , et al. May 15, 2 | 2012-05-15 |
Oral administration forms for administering a fixed tramadol and diclofenac combination Grant 8,173,164 - Bartholomaeus , et al. May 8, 2 | 2012-05-08 |
Salts of substituted allophanates and their use in drugs Grant 8,173,700 - Frank , et al. May 8, 2 | 2012-05-08 |
Sulfonylated 1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine compounds and their use as pharmaceuticals Grant 8,158,628 - Merla , et al. April 17, 2 | 2012-04-17 |
Substituted 1-oxa-3,8-diazaspiro[4.5]-decan-2-one-compounds and the use thereof for producing drugs Grant 8,153,795 - Sundermann , et al. April 10, 2 | 2012-04-10 |
Coated pellets Grant 8,147,874 - Ziegler , et al. April 3, 2 | 2012-04-03 |
Substituted heteroaryl derivatives Grant 8,138,187 - Zemolka , et al. March 20, 2 | 2012-03-20 |
Crystalline modifications of (1R,2R)-3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol Grant 8,134,032 - Gruss March 13, 2 | 2012-03-13 |
Substituted sulfonamide compounds Grant 8,124,624 - Oberboersch , et al. February 28, 2 | 2012-02-28 |
Spirocyclic cyclohexane compounds with analgesic activity Grant 8,124,788 - Merla , et al. February 28, 2 | 2012-02-28 |
Dosage form for hormonal contraception Grant 8,119,620 - Schramm , et al. February 21, 2 | 2012-02-21 |
Substituted sulfonamide compounds Grant 8,119,633 - Merla , et al. February 21, 2 | 2012-02-21 |
Substituted disulfonamide compounds Grant 8,119,805 - Reich , et al. February 21, 2 | 2012-02-21 |
Process for the production of an abuse-proofed solid dosage form Grant 8,114,384 - Arkenau , et al. February 14, 2 | 2012-02-14 |
Abuse-proofed dosage form Grant 8,114,383 - Bartholomaus , et al. February 14, 2 | 2012-02-14 |
Substituted amide compounds Grant 8,106,055 - Oberboersch , et al. January 31, 2 | 2012-01-31 |
Combination of gestagen and insulin sensitizer for treating PCOS Grant 8,097,604 - Schramm January 17, 2 | 2012-01-17 |
Heteroaryl substituted cyclohexyl-1,4-diamine compounds Grant 8,093,272 - Sundermann , et al. January 10, 2 | 2012-01-10 |
Method and device for ultrasound-pressing a tablet or a multiparticulate medicament Grant 8,088,322 - Arkenau-Maric , et al. January 3, 2 | 2012-01-03 |
Cyclohexyl-1, 4-diamine compounds Grant 8,088,763 - Sundermann , et al. January 3, 2 | 2012-01-03 |
Process for Preparing Spirocyclic Cyclohexane Compounds, Compositions Containing Such Compounds and Method of Using Such Compounds App 20110319440A1 - | 2011-12-29 |
Vanilloid receptor ligands, pharmaceutical compositions containing them, process for making them, and use thereof for treating pain and other conditions Grant 8,084,484 - Frank , et al. December 27, 2 | 2011-12-27 |
C-(2-phenyl-cyclohexyl)-methylamine compounds for therapy of fibromyalgia Grant 8,084,497 - Bloms-Funke , et al. December 27, 2 | 2011-12-27 |
Substituted nicotinamide compounds and uses thereof Grant 8,084,470 - Merla , et al. December 27, 2 | 2011-12-27 |
Abuse-proofed dosage form Grant 8,075,872 - Arkenau-Maric , et al. December 13, 2 | 2011-12-13 |
Substituted cyclohexylmethyl compounds Grant 8,058,475 - Oberboersch , et al. November 15, 2 | 2011-11-15 |
HCI polymorphs of 3-((2-(dimethylamino)methyl(cyclohex-1-yl)) phenol Grant 8,058,476 - Gruss , et al. November 15, 2 | 2011-11-15 |
Compositions containing spirocyclic cyclohexane compounds Grant 8,053,576 - Hinze , et al. November 8, 2 | 2011-11-08 |
Substituted 4,5,6,7-tetrahydro-isoxazolo[4,5-c]pyridine compounds and use thereof for producing medicaments Grant 8,048,879 - Sundermann , et al. November 1, 2 | 2011-11-01 |
Substituted 1-oxa-2,8-diaza-spiro[4,5]dec-2-ene derivatives and related treatment methods Grant 8,048,890 - Buschmann , et al. November 1, 2 | 2011-11-01 |
Spirocyclic cyclohexane compounds useful to treat substance dependency Grant 8,034,936 - Friderichs , et al. October 11, 2 | 2011-10-11 |
Cyclohexylacetic acid compounds Grant 8,017,630 - Hinze , et al. September 13, 2 | 2011-09-13 |
Substituted tetrahydropyrrolopyrazine compounds and the use thereof in the treatment and/or inhibition of pain Grant 8,017,772 - Merla , et al. September 13, 2 | 2011-09-13 |
Method of inhibiting inflammatory pain Grant 8,003,701 - Schiene , et al. August 23, 2 | 2011-08-23 |
Application system for a plaster containing an active ingredient and a controlled-release agent for said active ingredient Grant 7,994,382 - Bartholomaeus , et al. August 9, 2 | 2011-08-09 |
Crystalline forms of (-)-(1R,2R)-3-(3-dimethylamino-1-ethyl-2-methylpropyl)-phenol hydrochloride Grant 7,994,364 - Fischer , et al. August 9, 2 | 2011-08-09 |
Tapentadol for Treating Pain due to Osteoarthritis App 20100331425A1 - | 2010-12-30 |
Use of Axomadol for Treatment of Arthrosis Pain App 20100331424A1 - | 2010-12-30 |
Substituted Phenylureas and Phenylamides as Vanilloid Receptor Ligands App 20100331381A1 - | 2010-12-30 |