Patent | Date |
---|
Crystalline polymorphs of the free base of 2-hydroxy-6-((2-(1-isopropyl-1H-pyrazol-5-yl)pyridin-3-yl)methoxy)benzald- ehyde Grant 11,452,720 - Li , et al. September 27, 2 | 2022-09-27 |
Pyrrolidine-pyrazoles As Pyruvate Kinase Activators App 20220267337 - Setti; Lina Q. ;   et al. | 2022-08-25 |
Process For Preparation Of 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)methoxy)benzald- Ehyde App 20220144800 - Wang; Fang ;   et al. | 2022-05-12 |
Process For Synthesizing 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)-pyridin-3-yl)methoxy)benzal- Dehyde App 20220135533 - Li; Zhe ;   et al. | 2022-05-05 |
Substituted Benzaldehyde Compounds And Methods For Their Use In Increasing Tissue Oxygenation App 20220125786 - Metcalf; Brian ;   et al. | 2022-04-28 |
Compounds And Uses Thereof For The Modulation Of Hemoglobin App 20220119407 - Li; Zhe ;   et al. | 2022-04-21 |
Dosing Regimens For 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)methoxy)benzald- Ehyde App 20220110928 - Ramos; Eleanor L. ;   et al. | 2022-04-14 |
Ferroportin inhibitors and methods of use Grant 11,286,243 - Li , et al. March 29, 2 | 2022-03-29 |
Histone methyltransferase inhibitors Grant 11,254,651 - Yu , et al. February 22, 2 | 2022-02-22 |
Compounds and uses thereof for the modulation of hemoglobin Grant 11,236,109 - Li , et al. February 1, 2 | 2022-02-01 |
Azaindole Compounds As Histone Methyltransferase Inhibitors App 20210371417 - Yu; Chul ;   et al. | 2021-12-02 |
Substituted Benzaldehyde Compounds And Methods For Their Use In Increasing Tissue Oxygenation App 20210290619 - Metcalf; Brian ;   et al. | 2021-09-23 |
Tablets Comprising 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)methoxy)benzald- Ehyde App 20210283061 - Dalziel; Sean Mark ;   et al. | 2021-09-16 |
Process For Synthesizing 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)-pyridin-3-yl)methoxy)benzal- Dehyde App 20210284623 - Li; Zhe ;   et al. | 2021-09-16 |
Azaindole compounds as histone methyltransferase inhibitors Grant 11,111,243 - Yu , et al. September 7, 2 | 2021-09-07 |
Dosing Regimens For 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)methoxy)benzald- Ehyde App 20210267956 - Ramos; Eleanor L. ;   et al. | 2021-09-02 |
Compounds And Uses Thereof For The Modulation Of Hemoglobin App 20210261520 - Metcalf; Brian W. ;   et al. | 2021-08-26 |
Compounds and uses thereof for the modulation of hemoglobin Grant 11,053,195 - Xu , et al. July 6, 2 | 2021-07-06 |
Crystalline Polymorphs Of The Free Base Of 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)methoxy)benzald- Ehyde App 20210161876 - Li; Zhe ;   et al. | 2021-06-03 |
Dosing regimens for 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)methoxy)benzald- ehyde Grant 11,020,382 - Ramos , et al. June 1, 2 | 2021-06-01 |
Modulators of hemoglobin Grant 11,014,884 - Metcalf , et al. May 25, 2 | 2021-05-25 |
Histone Methyltransferase Inhibitors App 20210107876 - Yu; Ming ;   et al. | 2021-04-15 |
Modulators Of Hemoglobin App 20210047309 - Li; Zhe | 2021-02-18 |
Compounds and uses thereof for the modulation of hemoglobin Grant 10,858,317 - Xu , et al. December 8, 2 | 2020-12-08 |
Tricyclic Compounds As Histone Methyltransferase Inhibitors App 20200361896 - YU; Ming ;   et al. | 2020-11-19 |
Histone methyltransferase inhibitors Grant 10,829,452 - Yu , et al. November 10, 2 | 2020-11-10 |
Compounds and uses thereof for the modulation of hemoglobin Grant 10,829,470 - Metcalf , et al. November 10, 2 | 2020-11-10 |
Substituted heteroaryl aldehyde compounds and methods for their use in increasing tissue oxygenation Grant 10,822,326 - Metcalf , et al. November 3, 2 | 2020-11-03 |
Substituted benzaldehyde compounds and methods for their use in increasing tissue oxygenation Grant 10,806,733 - Metcalf , et al. October 20, 2 | 2020-10-20 |
Crystalline polymorphs of the free base of 2-hydroxy-6-((2-(1-isopropyl-1H-pyrazol-5-yl)pyridin-3-yl)methoxy)benzald- ehyde Grant 10,722,502 - Li , et al. | 2020-07-28 |
Methods of treatment Grant 10,695,330 - Li , et al. | 2020-06-30 |
Ferroportin Inhibitors And Methods Of Use App 20200190045 - LI; ZHE ;   et al. | 2020-06-18 |
Substituted Heteroaryl Aldehyde Compounds And Methods For Their Use In Increasing Tissue Oxygenation App 20200190058 - Metcalf; Brian ;   et al. | 2020-06-18 |
Modulators of hemoglobin Grant 10,683,285 - Li | 2020-06-16 |
Modulators Of Hemoglobin App 20200157085 - Li; Zhe | 2020-05-21 |
Modulators Of Hemoglobin App 20200140384 - Metcalf; Brian W. ;   et al. | 2020-05-07 |
Compounds And Uses Thereof For The Modulation Of Hemoglobin App 20200079732 - Xu; Qing ;   et al. | 2020-03-12 |
Process for synthesizing 2-hydroxy-6-((2-(1-isopropyl-1H-pyrazol-5-yl)-pyridin-3-yl)methoxy)benzal- dehyde Grant 10,577,345 - Li , et al. | 2020-03-03 |
Compounds And Uses Thereof For The Modulation Of Hemoglobin App 20200048280 - Li; Zhe ;   et al. | 2020-02-13 |
Tablets comprising 2-hydroxy-6-((2-(1-isopropyl-1H-pyrazol-5-yl)pyridin-3-yl)methoxy)benzald- ehyde Grant 10,493,035 - Dalziel , et al. De | 2019-12-03 |
Compounds and uses thereof for the modulation of hemoglobin Grant 10,450,269 - Xu , et al. Oc | 2019-10-22 |
Compounds and uses thereof for the modulation of hemoglobin Grant 10,435,393 - Xu , et al. O | 2019-10-08 |
Compounds And Uses Thereof For The Modulation Of Hemoglobin App 20190300477 - Xu; Qing ;   et al. | 2019-10-03 |
Crystalline Polymorphs Of The Free Base Of 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)methoxy)benzald- Ehyde App 20190255031 - Li; Zhe ;   et al. | 2019-08-22 |
Substituted heteroaryl aldehyde compounds and methods for their use in increasing tissue oxygenation Grant 10,377,741 - Metcalf , et al. A | 2019-08-13 |
Compounds And Uses Thereof For The Modulation Of Hemoglobin App 20190202782 - Xu; Qing ;   et al. | 2019-07-04 |
Compounds and uses thereof for the modulation of hemoglobin Grant 10,315,991 - Xu , et al. | 2019-06-11 |
Substituted Benzaldehyde Compounds And Methods For Their Use In Increasing Tissue Oxygenation App 20190160060 - Metcalf; Brian | 2019-05-30 |
Compounds and uses thereof for the modulation of hemoglobin Grant 10,266,551 - Li , et al. | 2019-04-23 |
Compounds And Uses Thereof For The Modulation Of Hemoglobin App 20190112287 - Metcalf; Brian W. ;   et al. | 2019-04-18 |
Methods Of Treatment App 20190111037 - Li; Zhe ;   et al. | 2019-04-18 |
Process For Synthesizing 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)-pyridin-3-yl)methoxy)benzal- Dehyde App 20190106404 - Li; Zhe ;   et al. | 2019-04-11 |
Histone Methyltransferase Inhibitors App 20190047981 - Yu; Ming ;   et al. | 2019-02-14 |
Compounds And Uses Thereof For The Modulation Of Hemoblogin App 20190010121 - Xu; Qing ;   et al. | 2019-01-10 |
Compounds And Uses Thereof For The Modulation Of Hemoglobin App 20190010176 - Harris; Jason R. | 2019-01-10 |
Substituted Heteroaryl Aldehyde Compounds And Methods For Their Use In Increasing Tissue Oxygenation App 20180354929 - Metcalf; Brian W. ;   et al. | 2018-12-13 |
Azaindole Compounds As Histone Methyltransferase Inhibitors App 20180354947 - Yu; Chul ;   et al. | 2018-12-13 |
Bridged bicyclic kallikrein inhibitors Grant 10,144,746 - Li , et al. De | 2018-12-04 |
Crystalline polymorphs of the free base of 2-hydroxy-6-((2-(1-isopropyl-1H-pyrazol-5-yl)pyridin-3-yl)methoxy)benzald- ehyde Grant 10,137,118 - Li , et al. November 27, 2 | 2018-11-27 |
Compounds and uses thereof for the modulation of hemoglobin Grant 10,100,040 - Li , et al. October 16, 2 | 2018-10-16 |
Substituted aldehyde compounds and methods for their use in increasing tissue oxygenation Grant 10,100,043 - Metcalf , et al. October 16, 2 | 2018-10-16 |
Crystalline Polymorphs Of The Free Base Of 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)methoxy)benzald- Ehyde App 20180289686 - Li; Zhe ;   et al. | 2018-10-11 |
Process for synthesizing 2-hydroxy-6-((2-(1-isopropyl-1H-pyrazol-5-yl)-pyridin-3-yl)methoxy)benzal- dehyde Grant 10,077,249 - Li , et al. September 18, 2 | 2018-09-18 |
Substituted benzaldehyde compounds and methods for their use in increasing tissue oxygenation Grant 10,034,879 - Metcalf , et al. July 31, 2 | 2018-07-31 |
Compounds And Uses Thereof For The Modulation Of Hemoglobin App 20180201577 - Xu; Qing ;   et al. | 2018-07-19 |
Bridged Bicyclic Kallikrein Inhibitors App 20180194780 - Li; Zhe ;   et al. | 2018-07-12 |
Compounds and uses thereof for the modulation of hemoglobin Grant 10,017,491 - Metcalf , et al. July 10, 2 | 2018-07-10 |
Compounds And Uses Thereof For The Modulation Of Hemoglobin App 20180186807 - Yee; Calvin W. ;   et al. | 2018-07-05 |
Histone Methyltransferase Inhibitors App 20180186745 - Yu; Ming ;   et al. | 2018-07-05 |
Methods of treatment Grant 10,004,725 - Dufu , et al. June 26, 2 | 2018-06-26 |
Compounds and uses thereof for the modulation of hemoglobin Grant 9,981,939 - Metcalf , et al. May 29, 2 | 2018-05-29 |
Tablets Comprising 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)methoxy)benzald- Ehyde App 20180125789 - Dalziel; Sean Mark ;   et al. | 2018-05-10 |
Substituted Benzaldehyde Compounds And Methods For Their Use In Increasing Tissue Oxygenation App 20180117040 - Metcalf; Brian ;   et al. | 2018-05-03 |
Compounds and uses thereof for the modulation of hemoglobin Grant 9,957,250 - Metcalf , et al. May 1, 2 | 2018-05-01 |
Compounds And Uses Thereof For The Modulation Of Hemoglobin App 20170355713 - HARRIS; Jason R. ;   et al. | 2017-12-14 |
Process For Synthesizing 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)-pyridin-3-yl)methoxy)benzal- Dehyde App 20170327484 - LI; Zhe ;   et al. | 2017-11-16 |
Bridged bicyclic kallikrein inhibitors Grant 9,815,853 - Li , et al. November 14, 2 | 2017-11-14 |
Bicyclic heteroaryl compounds and uses thereof for the modulation of hemoglobin Grant 9,802,900 - Li , et al. October 31, 2 | 2017-10-31 |
Compounds and uses thereof for the modulation of hemoglobin Grant 9,776,960 - Xu , et al. October 3, 2 | 2017-10-03 |
Pyrazolopyridine pyrazolopyrimidine and related compounds Grant 9,695,166 - Li , et al. July 4, 2 | 2017-07-04 |
Compounds And Uses Thereof For The Modulation Of Hemoglobin App 20170174654 - METCALF; Brian W. ;   et al. | 2017-06-22 |
Dosing Regimens For 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)methoxy)benzald- Ehyde App 20170157101 - Ramos; Eleanor L. ;   et al. | 2017-06-08 |
Substituted Heteroaryl Aldehyde Compounds And Methods For Their Use In Increasing Tissue Oxygenation App 20170107199 - METCALF; Brian W. ;   et al. | 2017-04-20 |
Compounds and uses thereof for the modulation of hemoglobin Grant 9,604,999 - Harris , et al. March 28, 2 | 2017-03-28 |
Bridged Bicyclic Kallikrein Inhibitors App 20160362427 - Li; Zhe ;   et al. | 2016-12-15 |
Crystalline Polymorphs Of The Free Base Of 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)methoxy)benzald- Ehyde App 20160346263 - LI; Zhe ;   et al. | 2016-12-01 |
Compounds And Uses Thereof For The Modulation Of Hemoglobin App 20160332984 - Metcalf; Brian W. ;   et al. | 2016-11-17 |
Methods Of Treatment App 20160303099 - Dufu; Kobina N. ;   et al. | 2016-10-20 |
Compounds and uses thereof for the modulation of hemoglobin Grant 9,458,139 - Xu , et al. October 4, 2 | 2016-10-04 |
Crystalline polymorphs of the free base of 2-hydroxy-6-((2-(1-isopropyl-1H-pyrazol-5-yl)pyridin-3-yl)methoxy)benzald- ehyde Grant 9,447,071 - Li , et al. September 20, 2 | 2016-09-20 |
Compounds and uses thereof for the modulation of hemoglobin Grant 9,422,279 - Metcalf , et al. August 23, 2 | 2016-08-23 |
Formulations Comprising Wetting Agents And Compounds For The Modulation Of Hemoglobin (s) App 20160206604 - METCALF; Brian W. | 2016-07-21 |
Crystalline 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)methoxy)benzald- Ehyde Ansolvate Salts App 20160207904 - LI; Zhe | 2016-07-21 |
Substituted Benzaldehyde Compounds And Methods For Their Use In Increasing Tissue Oxygenation App 20160206614 - METCALF; Brian ;   et al. | 2016-07-21 |
Compounds And Uses Thereof For The Modulation Of Hemoglobin App 20160152602 - Xu; Qing ;   et al. | 2016-06-02 |
Compounds And Uses Thereof For The Modulation Of Hemoglobin App 20160083348 - XU; Qing ;   et al. | 2016-03-24 |
Compounds And Uses Thereof For The Modulation Of Hemoglobin App 20160083343 - XU; Qing ;   et al. | 2016-03-24 |
Compounds And Uses Thereof For The Modulation Of Hemoglobin App 20160046613 - METCALF; Brian W. ;   et al. | 2016-02-18 |
Substituted Aldehyde Compounds And Methods For Their Use In Increasing Tissue Oxygenation App 20160039801 - METCALF; Brian ;   et al. | 2016-02-11 |
Compositions And Methods For The Modulation Of Hemoglobin (s) App 20160038474 - SINHA; Uma ;   et al. | 2016-02-11 |
Compounds And Uses Thereof For The Modulation Of Hemoglobin App 20160031904 - LI; Zhe ;   et al. | 2016-02-04 |
Compounds And Uses Thereof For The Modulation Of Hemoglobin App 20160031865 - LI; Zhe ;   et al. | 2016-02-04 |
1:1 adducts of sickle hemoglobin Grant 9,248,199 - Metcalf February 2, 2 | 2016-02-02 |
Compounds And Uses Thereof For The Modulation Of Hemoglobin App 20160024127 - HARRIS; Jason R. ;   et al. | 2016-01-28 |
Substituted Heteroaryl Aldehyde Compounds And Methods For Their Use In Increasing Tissue Oxygenation App 20150344483 - Metcalf; Brian ;   et al. | 2015-12-03 |
Substituted Benzaldehyde Compounds And Methods For Their Use In Increasing Tissue Oxygenation App 20150344472 - Metcalf; Brian ;   et al. | 2015-12-03 |
Pyrazolopyridine Pyrazolopyrimidine And Related Compounds App 20150315198 - Li; Zhe ;   et al. | 2015-11-05 |
Bicyclic Heteroaryl Compounds And Uses Thereof For The Modulation Of Hemoglobin App 20150259296 - Li; Zhe ;   et al. | 2015-09-17 |
Crystalline Polymorphs of the Free Base of 2-Hydroxy-6-((2-(1-isopropyl-1H-pyrazol-5-yl)pyridin-3-yl)methoxy)benzald- ehyde App 20150225366 - Li; Zhe | 2015-08-13 |
1:1 Adducts Of Sickle Hemoglobin App 20150209443 - Metcalf; Brian W. | 2015-07-30 |
Compounds And Uses Thereof For The Modulation Of Hemoglobin App 20150141465 - YEE; Calvin W. ;   et al. | 2015-05-21 |
Compounds And Uses Thereof For The Modulation Of Hemoglobin App 20150133430 - XU; Qing ;   et al. | 2015-05-14 |
Substituted benzaldehyde compounds and methods for their use in increasing tissue oxygenation Grant 9,018,210 - Metcalf , et al. April 28, 2 | 2015-04-28 |
Substituted heteroaryl aldehyde compounds and methods for their use in increasing tissue oxygenation Grant 9,012,450 - Metcalf , et al. April 21, 2 | 2015-04-21 |
Compounds And Uses Thereof For The Modulation Of Hemoglobin App 20150057251 - Harris; Jason R. | 2015-02-26 |
Compounds and uses thereof for the modulation of hemoglobin Grant 8,952,171 - Xu , et al. February 10, 2 | 2015-02-10 |
Compounds and uses thereof for the modulation of hemoglobin App 20140274961 - Metcalf; Brian W. ;   et al. | 2014-09-18 |
Compositions and methods for the modulation of hemoglobin (s) App 20140271591 - Sinha; Uma ;   et al. | 2014-09-18 |
Compounds and uses thereof for the modulation of hemoglobin App 20140275152 - Metcalf; Brian W. ;   et al. | 2014-09-18 |
Compounds and uses thereof for the modulation of hemoglobin App 20140275008 - Xu; Qing ;   et al. | 2014-09-18 |
Compounds and uses thereof for the modulation of hemoglobin App 20140275176 - Xu; Qing ;   et al. | 2014-09-18 |
Compounds and uses thereof for the modulation of hemoglobin App 20140275181 - Harris; Jason R. ;   et al. | 2014-09-18 |
Substituted Heteroaryl Aldehyde Compounds And Methods For Their Use In Increasing Tissue Oxygenation App 20130190316 - Metcalf; Brian ;   et al. | 2013-07-25 |
Substituted Benzaldehyde Compounds And Methods For Their Use In Increasing Tissue Oxygenation App 20130190315 - Metcalf; Brian ;   et al. | 2013-07-25 |