Patent | Date |
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ROR .gamma. modulators Grant 11,078,186 - Duan , et al. August 3, 2 | 2021-08-03 |
Heterocyclic compounds useful as modulators of TNF alpha Grant 10,865,191 - Xiao , et al. December 15, 2 | 2020-12-15 |
Tricyclic sulfones as ROR.gamma. modulators Grant 10,711,020 - Duan , et al. | 2020-07-14 |
Ror Gamma Modulators App 20200024257 - DUAN; Jingwu ;   et al. | 2020-01-23 |
Tricyclic Sulfones As Ror Gamma Modulators App 20190241588 - DUAN; Jingwu ;   et al. | 2019-08-08 |
Cyclic compounds useful as modulators of TNF .alpha. Grant 10,335,392 - Xiao , et al. | 2019-07-02 |
Tricyclic heterocyclic compounds useful as inhibitors of TNF Grant 10,308,652 - Wrobleski , et al. | 2019-06-04 |
Tricyclic sulfones as ROR.gamma. modulators Grant 10,273,259 - Duan , et al. | 2019-04-30 |
Substituted tricyclic heterocyclic compounds Grant 10,189,840 - Xiao , et al. Ja | 2019-01-29 |
Heterocyclic Compounds Useful As Modulators Of Tnf Alpha App 20180222883 - XIAO; Hai-Yun ;   et al. | 2018-08-09 |
Cyclic Compounds Useful As Modulators Of Tnf Alpha App 20180221344 - Xiao; Hai-Yun ;   et al. | 2018-08-09 |
Substituted Tricyclic Heterocyclic Compounds App 20180111936 - XIAO; Hai-Yun ;   et al. | 2018-04-26 |
Tricyclic Heterocyclic Compounds Useful As Inhibitors Of Tnf App 20180111937 - WROBLESKI; Stephen T. ;   et al. | 2018-04-26 |
Tricyclic Sulfones As Ror Gamma Modulators App 20180002358 - Duan; Jingwu ;   et al. | 2018-01-04 |
Tricyclic sulfones as ROR.gamma. modulators Grant 9,815,859 - Duan , et al. November 14, 2 | 2017-11-14 |
Carbocyclic sulfone ROR.gamma. modulators Grant 9,771,320 - Duan , et al. September 26, 2 | 2017-09-26 |
ROR.gamma. modulators Grant 9,725,443 - Dhar , et al. August 8, 2 | 2017-08-08 |
Cyclohexyl sulfone ROR.gamma. modulators Grant 9,708,253 - Duan , et al. July 18, 2 | 2017-07-18 |
ROR.gamma. modulators Grant 9,663,469 - Dhar , et al. May 30, 2 | 2017-05-30 |
Heterocyclic sulfone ROR.gamma. modulators Grant 9,637,455 - Duan , et al. May 2, 2 | 2017-05-02 |
TRICYCLIC SULFONES AS RORy MODULATORS App 20160326195 - Duan; Jingwu ;   et al. | 2016-11-10 |
Pyrrolidinyl Sulfone Derivatives And Their Use As Ror Gamma Modulators App 20160326108 - DUAN; Jingwu ;   et al. | 2016-11-10 |
Heterocyclic Sulfone Ror Gamma Modulators App 20160326115 - Duan; Jingwu ;   et al. | 2016-11-10 |
Cyclohexyl Sulfone Ror Gamma Modulators App 20160326104 - DUAN; Jingwu ;   et al. | 2016-11-10 |
Carbocyclic Sulfone Ror Gamma Modulators App 20160326103 - Duan; Jingwu ;   et al. | 2016-11-10 |
RORy MODULATORS App 20160318870 - Dhar; T.G Murali ;   et al. | 2016-11-03 |
Pyrrolidinyl sulfone ROR.gamma. modulators Grant 9,458,171 - Duan , et al. October 4, 2 | 2016-10-04 |
RORgamma MODULATORS App 20160229844 - Dhar; T. G. Murali ;   et al. | 2016-08-11 |
Pyrrolidinyl Sulfone Rorgamma Modulators App 20150191483 - Duan; Jingwu ;   et al. | 2015-07-09 |
Benzylpyrrolidinone derivatives as modulators of chemokine receptor activity Grant 9,040,526 - Mangion , et al. May 26, 2 | 2015-05-26 |
Pyrrolopyridazine JAK3 inhibitors and their use for the treatment of inflammatory and autoimmune diseases Grant 8,987,268 - Wrobleski , et al. March 24, 2 | 2015-03-24 |
Pyrrolopyridazine JAK3 inhibitors and their use for the treatment of inflammatory and autoimmune diseases Grant 08921368 - | 2014-12-30 |
Pyrrolopyridazine JAK3 inhibitors and their use for the treatment of inflammatory and autoimmune diseases Grant 8,921,368 - Wrobleski , et al. December 30, 2 | 2014-12-30 |
Azaindazoles as kinase inhibitors and use thereof Grant 8,846,673 - Duan , et al. September 30, 2 | 2014-09-30 |
Pyrrolopyridazine Jak3 Inhibitors And Their Use For The Treatment Of Inflammatory And Autoimmune Diseases App 20140011795 - Wrobleski; Stephen T. ;   et al. | 2014-01-09 |
Pyrrolopyridazine Jak3 Inhibitors And Their Use For The Treatment Of Inflammatory And Autoimmune Diseases App 20140011800 - Wrobleski; Stephen T. ;   et al. | 2014-01-09 |
Nicotinamide compounds useful as kinase modulators Grant 8,586,751 - De Lucca , et al. November 19, 2 | 2013-11-19 |
Indane modulators of glucocorticoid receptor, AP-1, and/or NF-.kappa.B activity and use thereof Grant 8,324,401 - Duan , et al. December 4, 2 | 2012-12-04 |
Benzylpyrrolidinone Derivatives As Modulators Of Chemokine Receptor Activity App 20120295899 - Mangion; Ian K. ;   et al. | 2012-11-22 |
Fused heteroaryl modulators of glucocorticoid receptor, AP-1, and/or NF-.kappa.B activity and use thereof Grant 8,304,539 - Duan , et al. November 6, 2 | 2012-11-06 |
Azaindazoles As Kinase Inhibitors And Use Thereof App 20120129852 - Duan; Jingwu ;   et al. | 2012-05-24 |
Nicotinamide Compounds Useful As Kinase Modulators App 20120082702 - DeLucca; George V. ;   et al. | 2012-04-05 |
Modulators of glucocorticoid receptor, AP-1, and/or NF-.kappa.B activity and use thereof Grant 8,034,940 - Weinstein , et al. October 11, 2 | 2011-10-11 |
Modulators of glucocorticoid receptor, AP-1, and/or NF-.kappa.B activity, and use thereof Grant 7,888,381 - Duan , et al. February 15, 2 | 2011-02-15 |
FUSED HETEROARYL MODULATORS OF GLUCOCORTICOID RECEPTOR, AP-1, AND/OR NF-kappaB ACTIVITY AND USE THEREOF App 20110002952 - Duan; Jingwu ;   et al. | 2011-01-06 |
INDANE MODULATORS OF GLUCOCORTICOID RECEPTOR, AP-1, AND/OR NF-kB ACTIVITY AND USE THEREOF App 20090325961 - Duan; Jingwu ;   et al. | 2009-12-31 |
Modulators of the glucocorticoid receptor, AP-1, and/or NF-.kappa.B activity and use thereof Grant 7,625,921 - Duan , et al. December 1, 2 | 2009-12-01 |
Barbituric acid derivatives as inhibitors of TNF-.alpha. converting enzyme (TACE) and/or matrix metalloproteinases Grant 7,595,317 - Duan , et al. September 29, 2 | 2009-09-29 |
Indane modulators of glucocorticoid receptor, AP-1, and/or NF-.kappa.B activity and use thereof Grant 7,592,461 - Duan , et al. September 22, 2 | 2009-09-22 |
Modulators of the glucocorticoid receptor, AP-1, and/or NF-.kappa.B activity and use thereof Grant 7,569,689 - Duan , et al. August 4, 2 | 2009-08-04 |
MODULATORS OF GLUCOCORTICOID RECEPTOR, AP-1, AND/OR NF-kB ACTIVITY AND USE THEREOF App 20090075995 - Weinstein; David S. ;   et al. | 2009-03-19 |
Hydantoins and related heterocycles as inhibitors of matrix metalloproteinases and/or TNF-.alpha. converting enzyme (TACE) Grant 7,482,372 - Sheppeck , et al. January 27, 2 | 2009-01-27 |
Barbituric acid derivatives as inhibitors of TNF-.alpha. converting enzyme (TACE) and/or matrix metalloproteinases Grant 7,294,624 - Duan , et al. November 13, 2 | 2007-11-13 |
Indane modulators of glucocorticoid receptor, AP-1, and/or NF/kB activity and use thereof App 20070185056 - Duan; Jingwu ;   et al. | 2007-08-09 |
BARBITURIC ACID DERIVATIVES AS INHIBITORS OF TNF-alpha CONVERTING ENZYME (TACE) AND/OR MATRIX METALLOPROTEINASES App 20070167451 - Duan; Jingwu ;   et al. | 2007-07-19 |
Modulators of glucocorticoid receptor, AP-1, and/or NF-kB activity, and use thereof App 20070129400 - Duan; Jingwu ;   et al. | 2007-06-07 |
Hydantoin derivatives as inhibitors of tumor necrosis factor-alpha converting enzyme (TACE) Grant 7,132,432 - Duan , et al. November 7, 2 | 2006-11-07 |
Cyclic sulfone derivatives as inhibitors of matrix metalloproteinases and/or TNF-.alpha. converting enzyme (TACE) Grant 7,015,217 - Duan , et al. March 21, 2 | 2006-03-21 |
Matrix metalloproteinase inhibitors Grant 6,989,139 - Decicco , et al. January 24, 2 | 2006-01-24 |
Cyclic .beta.-amino acid derivatives as inhibitors of matrix metalloproteases and TNF-.alpha. Grant 6,984,648 - Lu , et al. January 10, 2 | 2006-01-10 |
Spiro-cyclic .beta.-amino acid derivatives as inhibitors of matrix metalloproteases and TNF-.alpha. converting enzyme (TACE) Grant 6,962,938 - Ott , et al. November 8, 2 | 2005-11-08 |
Barbituric acid derivatives as inhibitors of TNF-.alpha. converting enzyme (TACE) and/or matrix metalloproteinases Grant 6,936,620 - Duan , et al. August 30, 2 | 2005-08-30 |
Modulators of the glucocorticoid receptor, AP-1, and/or NF-kB activity and use thereof App 20050182082 - Duan, Jingwu ;   et al. | 2005-08-18 |
Modulators of the glucocorticoid receptor, AP-1, and/or NF-kappaB activity and use thereof App 20050176716 - Duan, Jingwu ;   et al. | 2005-08-11 |
Hydantoins and related heterocycles as inhibitors of matrix metalloproteinases and/or TNF-alpha converting enzyme (TACE) App 20050171096 - Sheppeck, James E. ;   et al. | 2005-08-04 |
Hydantoins and related heterocycles as inhibitors of matrix metalloproteinases and/or TNF-.alpha. converting enzyme (TACE) Grant 6,906,053 - Sheppeck , et al. June 14, 2 | 2005-06-14 |
Hydantoins and related heterocycles as inhibitors of matrix metalloproteinases and/or TNF-.alpha. converting enzyme (TACE) Grant 6,890,915 - Sheppeck , et al. May 10, 2 | 2005-05-10 |
Bicyclic lactam derivatives as inhibitors of matrix metalloproteinases and/or TNF-.alpha. converting enzyme (TACE) Grant 6,884,806 - Decicco , et al. April 26, 2 | 2005-04-26 |
Matrix Metalloproteinase Inhibitors App 20050025702 - Decicco, Carl P. ;   et al. | 2005-02-03 |
Hydantoin derivatives as inhibitors of tumor necrosis factor-alpha converting enzyme (TACE) App 20040254231 - Duan, Jingwu ;   et al. | 2004-12-16 |
Hydantoins and related heterocycles as inhibitors of matrix metalloproteinases and/or TNF-alpha converting enzyme (TACE) App 20040209874 - Sheppeck, James E. ;   et al. | 2004-10-21 |
Cyclic beta-amino acid derivatives as inhibitors of matrix metalloproteases and TNF-alpha App 20040162426 - Lu, Zhonghui ;   et al. | 2004-08-19 |
Bicyclic hydroxamates as inhibitors of matrix metalloproteinases and/or TNF-.alpha. converting enzyme (TACE) Grant 6,770,647 - Sheppeck , et al. August 3, 2 | 2004-08-03 |
Spiro-cyclic beta-amino acid derivatives as inhibitors of matrix metalloproteases and TNF-alpha converting enzyme (TACE) App 20040132693 - Ott, Gregory R. ;   et al. | 2004-07-08 |
Cyclic .beta.-amino acid derivatives as inhibitors of matrix metalloproteases and TNF-.alpha. Grant 6,743,807 - Duan , et al. June 1, 2 | 2004-06-01 |
Cyclic hydroxamic acids as inhibitors of matrix metalloproteinases and/or TNF- .alpha. converting enzyme (TACE) Grant 6,740,649 - Ott , et al. May 25, 2 | 2004-05-25 |
Beta-amino acid derivatives as inhibitors of matrix metalloproteases and TNF-alpha App 20040072802 - Duan, Jingwu ;   et al. | 2004-04-15 |
Spiro-cyclic .beta.-amino acid derivatives as inhibitors of matrix metalloproteases and TNF-.alpha. converting enzyme (TACE) Grant 6,720,329 - Ott , et al. April 13, 2 | 2004-04-13 |
Amide derivatives as inhibitors of matrix metalloproteinases, TNF-.alpha., and aggrecanase Grant 6,689,771 - Duan , et al. February 10, 2 | 2004-02-10 |
Barbituric acid derivatives as inhibitors of TNF-alpha converting enzyme (TACE) and/or matrix metalloproteinases App 20030229084 - Duan, Jingwu ;   et al. | 2003-12-11 |
Combined use of tace inhibitors and COX2 inhibitors as anti-inflammatory agents App 20030225054 - Duan, Jingwu | 2003-12-04 |
Beta-sulfone derivatives as inhibitors of matrix metalloproteinases and/or TNF-alpha converting enzyme (TACE) App 20030212056 - Duan, Jingwu ;   et al. | 2003-11-13 |
Bicyclic lactam derivatives as inhibitors of matrix metalloproteinases and/or TNF-alpha converting enzyme (TACE) App 20030181438 - Decicco, Carl P. ;   et al. | 2003-09-25 |
Lactam metalloprotease inhibitors Grant 6,620,823 - Maduskuie , et al. September 16, 2 | 2003-09-16 |
Barbituric acid derivatives as inhibitors of TNF-alpha converting enzyme (TACE) and/or matrix metalloproteinases App 20030166647 - Duan, Jingwu ;   et al. | 2003-09-04 |
Lactam metalloprotease inhibitors Grant 6,610,731 - Duan , et al. August 26, 2 | 2003-08-26 |
Cyclic sulfone derivatives as inhibitors of matrix metalloproteinases and/or TNF-Alpha converting enzyme (TACE) App 20030149031 - Duan, Jingwu ;   et al. | 2003-08-07 |
Cyclic hydroxamic acids as inhibitors of matrix metalloproteinases and/or TNF-alpha converting enzyme (TACE) App 20030139388 - Ott, Gregory R. ;   et al. | 2003-07-24 |
Novel lactam metalloprotease inhibitors App 20030134827 - Duan, Jingwu ;   et al. | 2003-07-17 |
Hydantoins and related heterocycles as inhibitors of matrix metalloproteinases and/or TNF-alpha converting enzyme (TACE) App 20030130273 - Sheppeck, James E. ;   et al. | 2003-07-10 |
Bicyclic hydroxamates as inhibitors of matrix metalloproteinases and/or TNF-alpha converting enzyme (TACE) App 20030130257 - Sheppeck, James E. ;   et al. | 2003-07-10 |
Spiro-cyclic beta-amino acid derivatives as inhibitors of matrix metalloproteases and TNF-alpha converting enzyme (TACE) App 20030087882 - Ott, Gregory R. ;   et al. | 2003-05-08 |
Novel amide derivatives as inhibitors of matrix metalloproteinases, TNF-alpha, and aggrecanase App 20030032803 - Duan, Jingwu ;   et al. | 2003-02-13 |
Lactam inhibitors of matrix metalloproteinases, TNF-.alpha. and aggrecanase Grant 6,495,548 - Duan December 17, 2 | 2002-12-17 |
.beta.-amino acid derivatives as inhibitors of matrix metalloproteases and TNF-.alpha. Grant 6,495,565 - Duan , et al. December 17, 2 | 2002-12-17 |
Lactam metalloprotease inhibitors Grant 6,403,632 - Duan , et al. June 11, 2 | 2002-06-11 |
Amide derivatives as inhibitors of matrix metalloproteinases, TNF-.alpha., and aggrecanase Grant 6,376,665 - Duan , et al. April 23, 2 | 2002-04-23 |
Novel lactam metalloprotease inhibitors App 20020042398 - Maduskuie, Thomas P. ;   et al. | 2002-04-11 |
Cyclic beta-amino acid derivatives as inhibitors of matrix metalloproteases and TNF-alpha App 20020016336 - Duan, Jingwu ;   et al. | 2002-02-07 |
Beta-Amino-Acid derivatives as inhibitors of matrix metalloproteases and TNF-Alpha App 20020013341 - Duan, Jingwu ;   et al. | 2002-01-31 |
Lactam metalloprotease inhibitors Grant 6,057,336 - Duan , et al. May 2, 2 | 2000-05-02 |