Patent | Date |
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Gene site saturation mutagenesis App 20090130718 - Short; Jay M. | 2009-05-21 |
Phospholipases, Nucleic Acids Encoding Them and Methods for Making and Using Them App 20080317731 - Gramatikova; Svetlana ;   et al. | 2008-12-25 |
Method of DNA Shuffling with Polynucleotides Produced by Blocking or Interrupting a Synthesis or Amplification Process App 20080248464 - Short; Jay M. | 2008-10-09 |
Nanoarchaeum genome, Nanoarchaeum polypeptides and nucleic acids encoding them and methods for making and using them App 20080168572 - Stetter; Karl O. ;   et al. | 2008-07-10 |
Nucleic Acids Encoding Polypeptides Having Amylase Activity And Methods Of Making And Using Them App 20080047037 - Callen; Walter ;   et al. | 2008-02-21 |
Polypeptides Having Amylase Activity And Methods Of Making And Using Them App 20080032378 - CALLEN; Walter ;   et al. | 2008-02-07 |
Vaccines App 20070286871 - Hickle; Leslie ;   et al. | 2007-12-13 |
P450 Enzymes, Nucleic Acids Encoding Them And Methods Of Making And Using Them App 20070231820 - Weiner; David ;   et al. | 2007-10-04 |
Methods For Using Polypeptides Having Amylase Activity And Nucleic Acids Encoding Them App 20070161099 - Callen; Walter ;   et al. | 2007-07-12 |
Phytase expression systems and methods of making and using them Grant 7,232,677 - Short , et al. June 19, 2 | 2007-06-19 |
P450 enzymes, nucleic acids encoding them and methods of making and using them Grant 7,232,672 - Weiner , et al. June 19, 2 | 2007-06-19 |
Phospholipases, nucleic acids encoding them and methods for making and using them Grant 7,226,771 - Gramatikova , et al. June 5, 2 | 2007-06-05 |
Glucosidases, nucleic acids encoding them and methods for making and using them App 20070056053 - Gray; Kevin ;   et al. | 2007-03-08 |
Synthesis of synthons for the manufacture of bioactive compounds App 20070015260 - Wong; Chi-Huey ;   et al. | 2007-01-18 |
Enzymes having dehalogenase activity and methods of use thereof App 20060275804 - Short; Jay M. ;   et al. | 2006-12-07 |
Microbially-expressed thermotolerant phytase for animal feed Grant 7,138,260 - Lanahan , et al. November 21, 2 | 2006-11-21 |
Proteases, nucleic acids encoding them and methods for making and using them App 20060259995 - Cayouette; Michelle ;   et al. | 2006-11-16 |
Microbially expressed thermotolerant phytase for animal feed Grant 7,135,323 - Lanahan , et al. November 14, 2 | 2006-11-14 |
Pectate lyases, nucleic encoding them and methods for making and using them App 20060210971 - Kerovuo; Janne ;   et al. | 2006-09-21 |
Enzymes having dehalogenase activity and methods of use thereof Grant 7,078,504 - Short , et al. July 18, 2 | 2006-07-18 |
Phytases, nucleic acids encoding them and methods for making and using them Grant 7,078,035 - Short , et al. July 18, 2 | 2006-07-18 |
Polypeptides having polymerase activity and methods of use thereof Grant 7,056,703 - Callen , et al. June 6, 2 | 2006-06-06 |
Assays for identifying .alpha.-galactosidases Grant 7,056,691 - Short , et al. June 6, 2 | 2006-06-06 |
Enzymes having high temperature polymerase activity and methods of use thereof Grant 7,049,101 - Callen , et al. May 23, 2 | 2006-05-23 |
Construction and use of catalogued nucleic acid libraries that contain advantageously adjusted representations of defined components App 20060088821 - Short; Jay | 2006-04-27 |
Whole cell engineering by mutagenizing a substantial portion of a starting genome, combining mutations, and optionally repeating Grant 7,033,781 - Short April 25, 2 | 2006-04-25 |
GigaMatrix holding tray having through-hole wells Grant 7,019,827 - Lafferty March 28, 2 | 2006-03-28 |
Combinatorial screening of mixed populations of organisms Grant 7,018,793 - Short March 28, 2 | 2006-03-28 |
.alpha.galactosidases and methods of using them Grant 6,987,009 - Murphy , et al. January 17, 2 | 2006-01-17 |
.alpha.-galactosidases and methods for making and using them Grant 6,987,016 - Murphy , et al. January 17, 2 | 2006-01-17 |
Epoxide hydrolases, nucleic acids encoding them and methods of making and using them Grant 6,979,733 - Zhao , et al. December 27, 2 | 2005-12-27 |
Capillary array-based enzyme screening Grant 6,972,183 - Lafferty , et al. December 6, 2 | 2005-12-06 |
.alpha.-galactosidases and methods for making and using them Grant 6,949,369 - Murphy , et al. September 27, 2 | 2005-09-27 |
Epoxide hydrolases, nucleic acids encoding them and methods for making and using them Grant 6,943,001 - Zhao , et al. September 13, 2 | 2005-09-13 |
Exonuclease-mediated nucleic acid reassembly in directed evolution Grant 6,939,689 - Short , et al. September 6, 2 | 2005-09-06 |
Stackable sample holding plate with robot removable lid Grant 6,918,738 - Lafferty , et al. July 19, 2 | 2005-07-19 |
Positioning system for moving a selected station of a holding plate to a predetermined location for interaction with a probe App 20050118707 - Lafferty, William Michael | 2005-06-02 |
Phosholipases, nucleic acids encoding them and methods for making and using them App 20050108789 - Gramatikova, Svetlana ;   et al. | 2005-05-19 |
High throughput screening for novel Bioactivities Grant 6,872,526 - Short , et al. March 29, 2 | 2005-03-29 |
High throughput screening for sequences of interest App 20050064498 - Short, Jay M. ;   et al. | 2005-03-24 |
Capillary array-based sample screening Grant 6,866,824 - Lafferty , et al. March 15, 2 | 2005-03-15 |
High throughput screening for novel bioactivities App 20050040550 - Short, Jay M. ;   et al. | 2005-02-24 |
Recombinant bacterial phytases and uses thereof Grant 6,855,365 - Short , et al. February 15, 2 | 2005-02-15 |
Gene cluster screening of clones having DNA from mixed populations of organisms Grant 6,849,395 - Short February 1, 2 | 2005-02-01 |
Screening for novel compounds which regulate biological interactions Grant 6,846,627 - Short January 25, 2 | 2005-01-25 |
Method for high throughput screening of an environmental library Grant 6,806,048 - Short , et al. October 19, 2 | 2004-10-19 |
Method for intensifying the optical detection of samples that are held in solution in the through-hole wells of a holding tray Grant 6,798,520 - Lafferty September 28, 2 | 2004-09-28 |
Capillary array-based sample screening Grant 6,794,127 - Lafferty , et al. September 21, 2 | 2004-09-21 |
Methods for obtaining a desired bioactivity or biomolecule using DNA libraries from an environmental source Grant 6,790,605 - Short September 14, 2 | 2004-09-14 |
End selection in directed evolution Grant 6,773,900 - Short , et al. August 10, 2 | 2004-08-10 |
Saturation mutageneis in directed evolution Grant 6,764,835 - Short July 20, 2 | 2004-07-20 |
Device for effecting heat transfer with a solution held in a through-hole well of a holding tray Grant 6,764,818 - Lafferty July 20, 2 | 2004-07-20 |
End selection in directed evolution Grant 6,740,506 - Short , et al. May 25, 2 | 2004-05-25 |
Phytase-containing foodstuffs and methods of making and using them Grant 6,720,014 - Short , et al. April 13, 2 | 2004-04-13 |
Directed evolution of thermophilic enzymes Grant 6,713,281 - Short March 30, 2 | 2004-03-30 |
End selection in directed evolution Grant 6,713,282 - Short , et al. March 30, 2 | 2004-03-30 |
Non-stochastic generation of genetic vaccines and enzymes Grant 6,713,279 - Short March 30, 2 | 2004-03-30 |
Exonuclease-mediated gene assembly in directed evolution Grant 6,709,841 - Short March 23, 2 | 2004-03-23 |
Processes for making (R)-ethyl 4-cyano-3-hydroxybutyric acid App 20040053378 - Burk, Mark J. ;   et al. | 2004-03-18 |
Assays and kits for detecting the presence of nitriles and/or cyanide App 20040038419 - Weiner, David Paul ;   et al. | 2004-02-26 |
End selection in directed evolution Grant 6,696,275 - Short , et al. February 24, 2 | 2004-02-24 |
Whole cell engineering using real-time metabolic flux analysis App 20040033975 - Fu, Pengcheng ;   et al. | 2004-02-19 |
Enzymes having secondary amidases activity and methods of use thereof App 20040023257 - Barton, Nelson R. ;   et al. | 2004-02-05 |
Amylases, nucleic acids encoding them and methods for making and using them App 20040018607 - Callen, Walter ;   et al. | 2004-01-29 |
Nitrilases, nucleic acids encoding them and methods for making and using them App 20040014195 - DeSantis, Grace ;   et al. | 2004-01-22 |
Chimeric antigen binding molecules and methods for making and using them App 20040009498 - Short, Jay M. | 2004-01-15 |
Protein activity screening of clones having DNA from uncultivated microorganisms Grant 6,677,115 - Short January 13, 2 | 2004-01-13 |
Biocatalytic reduction of nitro groups App 20040005676 - Greenberg, William ;   et al. | 2004-01-08 |
Phospholipases, nucleic acids encoding them and methods for making and using them App 20040005604 - Gramatikova, Svetlana ;   et al. | 2004-01-08 |
Catalases App 20040005655 - Robertson, Dan E. ;   et al. | 2004-01-08 |
Chimeric cannulae proteins, nucleic acids encoding them and methods for making and using them App 20040006778 - Barton, Nelson R. ;   et al. | 2004-01-08 |
Methods for purifying annealed double-stranded oligonucleotides lacking base pair mismatches or nucleotide gaps Grant 6,673,552 - Frey January 6, 2 | 2004-01-06 |
Enzyme kits and libraries Grant 6,656,677 - Short December 2, 2 | 2003-12-02 |
Novel antigen binding molecules for therapeutic, diagnostic, prophylactic, enzymatic, industrial, and agricultural applications, and methods for generating and screening thereof App 20030219752 - Short, Jay M. | 2003-11-27 |
Methods for purifying double-stranded nucleic acids lacking base pair mismatches or nucleotide gaps App 20030215837 - Frey, Gerhard ;   et al. | 2003-11-20 |
High Throughput Fluorescence-based Screening For Novel Enzymes App 20030215798 - SHORT, JAY ;   et al. | 2003-11-20 |
Exonuclease-mediated nucleic acid reassembly in directed evolution Grant 6,635,449 - Short October 21, 2 | 2003-10-21 |
End selection in directed evolution App 20030194763 - Short, Jay M. ;   et al. | 2003-10-16 |
Gigamatrix holding tray Grant D480,814 - Lafferty , et al. October 14, 2 | 2003-10-14 |
Altered thermostability of enzymes Grant 6,632,600 - Short October 14, 2 | 2003-10-14 |
Nucleic acids and proteins from Cenarchaeum symbiosum Grant 6,632,937 - Swanson , et al. October 14, 2 | 2003-10-14 |
Nucleic acids and proteins from cenarchaeum symbiosum App 20030175708 - Swanson, Ronald V. ;   et al. | 2003-09-18 |
Microbial enrichment using a container having a plurality of solid support particles Grant 6,610,528 - Mathur , et al. August 26, 2 | 2003-08-26 |
Synthetic ligation reassembly in directed evolution Grant 6,605,449 - Short August 12, 2 | 2003-08-12 |
High throughput screening of mycelia for bioactivities or biomolecules Grant 6,602,675 - Short , et al. August 5, 2 | 2003-08-05 |
Products of manufacture and processes for peptide synthesis App 20030143664 - Desantis, Grace ;   et al. | 2003-07-31 |
Methods for purifying annealed double-stranded oligonucleotides lacking base pair mismatches or nucleotide gaps App 20030134289 - Frey, Gerhard | 2003-07-17 |
Nitrilases App 20030124698 - DeSantis, Grace ;   et al. | 2003-07-03 |
Methods For Identifying A Desired Enzymatic Activity App 20030119052 - SHORT, JAY M. | 2003-06-26 |
Microbial enrichment using a container having a plurality of solid support particles App 20030119171 - Mathur, Eric J. ;   et al. | 2003-06-26 |
Phytases, nucleic acids encoding them and methods for making and using them App 20030103958 - Short, Jay M. ;   et al. | 2003-06-05 |
Production and use of normalized DNA libraries App 20030104440 - Short, Jay M. ;   et al. | 2003-06-05 |
Saturation mutagenesis in directed evolution Grant 6,562,594 - Short May 13, 2 | 2003-05-13 |
Screening for novel bioactivities Grant 6,555,315 - Short April 29, 2 | 2003-04-29 |
Synthetic ligation reassembly in directed evolution Grant 6,537,776 - Short March 25, 2 | 2003-03-25 |
Nucleic acids and proteins from cenarchaeum symbiosum App 20030054364 - Swanson, Ronald V. ;   et al. | 2003-03-20 |
Esterases App 20030054530 - Robertson, Dan E. ;   et al. | 2003-03-20 |
Recombinant bacterial phytases and uses thereof App 20030049815 - Short, Jay M. | 2003-03-13 |
Cellular engineering, protein expression profiling, differential labeling of peptides, and novel reagents therefor App 20030044864 - Short, Jay M. ;   et al. | 2003-03-06 |
Protein activity screening of clones having DNA from uncultivated microorganisms Grant 6,528,249 - Short March 4, 2 | 2003-03-04 |
Transaminases and aminotranferases App 20030040092 - Warren, Patrick V. ;   et al. | 2003-02-27 |
Exonuclease-mediated nucleic acid reassembly in directed evolution App 20030036116 - Short, Jay M. | 2003-02-20 |
Peptide synthesis method App 20030032083 - Burk, Mark J. ;   et al. | 2003-02-13 |
Nucleic acids and proteins from cenarchaeum symbiosum App 20020198365 - Swanson, Ronald V. ;   et al. | 2002-12-26 |
Method for screening for enzyme activity App 20020187489 - Short, Jay M. | 2002-12-12 |
Method of DNA shuffling Grant 6,489,145 - Short December 3, 2 | 2002-12-03 |
Protein Activity Screening Of Clones Having Dna From Uncultivated Microorganisms App 20020172944 - SHORT, JAY M. ;   et al. | 2002-11-21 |
Non-stochastic generation of genetic vaccines Grant 6,479,258 - Short November 12, 2 | 2002-11-12 |
Enzymes having high temperature polymerase activity and methods of use thereof App 20020164618 - Callen, Walter ;   et al. | 2002-11-07 |
Combinatorial screening of mixed populations of organisms App 20020164580 - Short, Jay M. | 2002-11-07 |
Esterases App 20020164725 - Robertson, Dan E. ;   et al. | 2002-11-07 |
Enzymes having alpha-galactosidase activity and methods of use thereof App 20020160464 - Short, Jay M. ;   et al. | 2002-10-31 |
Nucleic acids and proteins from cenarchaeum symbiosum App 20020160476 - Swanson, Ronald V. ;   et al. | 2002-10-31 |
Method for screening enzyme activity App 20020155489 - Short, Jay M. | 2002-10-24 |
Enzymes having alpha-galactosidase activity and methods of use thereof App 20020150997 - Short, Jay M. ;   et al. | 2002-10-17 |
High throughput screening for novel enzymes App 20020150949 - Short, Jay M. ;   et al. | 2002-10-17 |
Exonuclease-mediated gene assembly in directed evolution App 20020142394 - Short, Jay M. | 2002-10-03 |
Enzymes having alpha-galactosidase activity and methods of use thereof App 20020137116 - Short, Jay M. ;   et al. | 2002-09-26 |
Hydrolase enzymes and their use in kinetic resolution App 20020137171 - Short, Jay ;   et al. | 2002-09-26 |
Sequence based screening Grant 6,455,254 - Short September 24, 2 | 2002-09-24 |
Enzymes having high temperature polymerase activity and methods of use thereof App 20020132997 - Callen, Walter ;   et al. | 2002-09-19 |
High throughput screening for novel enzymes App 20020127560 - Short, Jay M. ;   et al. | 2002-09-12 |
Production and use of normalized DNA libraries Grant 6,444,426 - Short , et al. September 3, 2 | 2002-09-03 |
Enzymes having alpha-galactosidase activity and methods of use thereof App 20020119515 - Short, Jay M. ;   et al. | 2002-08-29 |
Enzymes having alpha-galactosidase activity and methods of use thereof App 20020119550 - Short, Jay M. ;   et al. | 2002-08-29 |
Enzymes having alpha-galactosidase activity and methods of use thereof App 20020120108 - Short, Jay M. ;   et al. | 2002-08-29 |
Method of DNA shuffling with polynucleotides produced by blocking or interrupting a synthesis or amplification process Grant 6,440,668 - Short August 27, 2 | 2002-08-27 |
Enzymes having alpha-galactosidase activity and methods of use thereof App 20020115099 - Short, Jay M. ;   et al. | 2002-08-22 |
Enzymes having alpha-galactosidase activity and methods of use thereof App 20020115100 - Short, Jay M. ;   et al. | 2002-08-22 |
Enzymes having high temperature polymerase activity and methods of use thereof App 20020115108 - Callen, Walter ;   et al. | 2002-08-22 |
Chloramphenicol biosynthetic pathway and gene cluster App 20020072062 - Paradkar, Ashish ;   et al. | 2002-06-13 |
Screening for novel bioactivities Grant 6,368,798 - Short April 9, 2 | 2002-04-09 |
Exonuclease-mediated nucleic acid reassembly in directed evolution Grant 6,361,974 - Short , et al. March 26, 2 | 2002-03-26 |
End selection in directed evolution Grant 6,358,709 - Short , et al. March 19, 2 | 2002-03-19 |
Exonucease-mediated gene assembly in directed evolution Grant 6,352,842 - Short , et al. March 5, 2 | 2002-03-05 |
Method for screening for enzyme activity Grant 6,344,328 - Short February 5, 2 | 2002-02-05 |
Directed evolution of thermophilic enzymes Grant 6,335,179 - Short January 1, 2 | 2002-01-01 |
Recombinant bacterial phytases and uses thereof App 20010055788 - Short, Jay M. ;   et al. | 2001-12-27 |
Gene expression library produced from DNA from uncultivated microorganisms and methods for making the same Grant 6,280,926 - Short August 28, 2 | 2001-08-28 |
Carboxymethyl cellulose from thermotoga maritima Grant 6,245,547 - Mathur , et al. June 12, 2 | 2001-06-12 |
End selection in directed evolution Grant 6,238,884 - Short , et al. May 29, 2 | 2001-05-29 |
Phytase Grant 6,190,897 - Kretz February 20, 2 | 2001-02-20 |
Recombinant bacterial phytases and uses thereof Grant 6,183,740 - Short , et al. February 6, 2 | 2001-02-06 |
High throughput screening for novel enzymes Grant 6,174,673 - Short , et al. January 16, 2 | 2001-01-16 |
Saturation mutagenesis in directed evolution Grant 6,171,820 - Short January 9, 2 | 2001-01-09 |
Screening methods for enzymes and enzyme kits Grant 6,168,919 - Short January 2, 2 | 2001-01-02 |
Phytase Grant 6,110,719 - Kretz August 29, 2 | 2000-08-29 |
Screening for novel bioactivities Grant 6,057,103 - Short May 2, 2 | 2000-05-02 |
Method for screening for enzyme activity Grant 6,054,267 - Short April 25, 2 | 2000-04-25 |
Screening for novel bioactivities Grant 6,030,779 - Short February 29, 2 | 2000-02-29 |
Enzyme kits and libraries Grant 6,004,788 - Short December 21, 1 | 1999-12-21 |
Production and use of normalized DNA libraries Grant 6,001,574 - Short , et al. December 14, 1 | 1999-12-14 |
Amidase Grant 5,985,646 - Murphy , et al. November 16, 1 | 1999-11-16 |
Method of DNA reassembly by interrupting synthesis Grant 5,965,408 - Short October 12, 1 | 1999-10-12 |
Transminases and amnotransferases Grant 5,962,283 - Warren , et al. October 5, 1 | 1999-10-05 |
Carboxymethyl cellulase fromthermotoga maritima Grant 5,962,258 - Mathur , et al. October 5, 1 | 1999-10-05 |
.alpha.-galactosidase Grant 5,958,751 - Murphy , et al. September 28, 1 | 1999-09-28 |
Protein activity screening of clones having DNA from uncultivated microorganisms Grant 5,958,672 - Short September 28, 1 | 1999-09-28 |
Isolation and identification of polymerases Grant 5,948,666 - Callen , et al. September 7, 1 | 1999-09-07 |
Esterases Grant 5,942,430 - Robertson , et al. August 24, 1 | 1999-08-24 |
Catalases Grant 5,939,300 - Robertson , et al. August 17, 1 | 1999-08-17 |
Production of enzymes having desired activities by mutagenesis Grant 5,939,250 - Short August 17, 1 | 1999-08-17 |
Carboxymethyl cellulase from Thermotoga maritima Grant 5,925,749 - Mathur , et al. July 20, 1 | 1999-07-20 |
Phytase Grant 5,876,997 - Kretz March 2, 1 | 1999-03-02 |
Directed evolution of thermophilic enzymes Grant 5,830,696 - Short November 3, 1 | 1998-11-03 |
Transaminases and aminotransferases Grant 5,814,473 - Warren , et al. September 29, 1 | 1998-09-29 |
Endoglucanases Grant 5,789,228 - Lam , et al. August 4, 1 | 1998-08-04 |
Production and use of normalized DNA libraries Grant 5,763,239 - Short , et al. June 9, 1 | 1998-06-09 |