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Cyclic di-nucleotide compounds as sting agonists Grant 11,453,697 - Altman , et al. September 27, 2 | 2022-09-27 |
Combinations of PD-1 antagonists and benzo [b] thiophene STING agonists for cancer treatment Grant 11,312,772 - Cemerski , et al. April 26, 2 | 2022-04-26 |
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Cyclic Di-Nucleotide Compounds as STING Agonists App 20220033431 - Altman; Michael D. ;   et al. | 2022-02-03 |
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Cyclic Di-Nucleotide Compounds as STING Agonists App 20220024964 - Altman; Michael D. ;   et al. | 2022-01-27 |
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Arginase Inhibitors And Methods Of Use App 20210163505 - Achab; Abdelghani Abe ;   et al. | 2021-06-03 |
C5-C6-oxacyclic fused iminothiazine dioxide compounds bearing an ether linker as BACE inhibitors, compositions, and their use Grant 11,008,338 - Wu , et al. May 18, 2 | 2021-05-18 |
Combinations of PD-1 Antagonists and Benzo[b]thiophene STING Agonists for Cancer Treatment App 20210130466 - CEMERSKI; Saso ;   et al. | 2021-05-06 |
Arginase Inhibitors And Methods Of Use App 20210040127 - Achab; Abdelghani Abe ;   et al. | 2021-02-11 |
Aza-benzothiophene Compounds As Sting Agonists App 20210009608 - Altman; Michael D. ;   et al. | 2021-01-14 |
Benzo[b]thiophene STING Agonists for Cancer Treatment App 20200330427 - CEMERSKI; Saso ;   et al. | 2020-10-22 |
Sting agonist compounds Grant 10,793,557 - Altman , et al. October 6, 2 | 2020-10-06 |
Cyclic di-nucleotide compounds as sting agonists Grant 10,766,919 - Altman , et al. Sep | 2020-09-08 |
Cyclic di-nucleotide compounds as STING agonists Grant 10,759,825 - Altman , et al. Sep | 2020-09-01 |
Cyclic di-nucleotide compounds as STING agonists Grant 10,738,074 - Altman , et al. A | 2020-08-11 |
Benzo[b]thiophene compounds as STING agonists Grant 10,730,849 - Altman , et al. | 2020-08-04 |
N3-substituted Iminopyrimidinones As Antimalarial Agents App 20200230140 - Khan; Tanweer A. ;   et al. | 2020-07-23 |
Compounds For The Treatment Of Malaria App 20200223220 - Khan; Tanweer A. ;   et al. | 2020-07-16 |
C5-C6-Oxacyclic Fused Iminothiazine Dioxide Compounds Bearing an Ether Linker as BACE Inhibitors, Compositions, and Their Use App 20200216466 - Wu; Wen-Lian ;   et al. | 2020-07-09 |
Benzo[b]thiophene compounds as STING agonists Grant 10,703,738 - Altman , et al. | 2020-07-07 |
C5-C6-oxacyclic fused iminothiazine dioxide compounds bearing an ether linker as BACE inhibitors, compositions, and their use Grant 10,689,401 - Wu , et al. | 2020-06-23 |
Cyclic Dinucleotide Sting Agonists For Cancer Treatment App 20200113924 - Cemerski; Saso ;   et al. | 2020-04-16 |
C5-C6-oxacyclic fused iminothiadiazine dioxide compounds bearing an ether linker as BACE inhibitors, compositions, and their use Grant 10,604,534 - Walsh , et al. | 2020-03-31 |
Cyclic Di-nucleotide Compounds As Sting Agonists App 20200062798 - WU; Wen-Lian ;   et al. | 2020-02-27 |
BENZO[b]THIOPHENE COMPOUNDS AS STING AGONISTS App 20190337918 - Altman; Michael D. ;   et al. | 2019-11-07 |
BENZO[b]THIOPHENE COMPOUNDS AS STING AGONISTS App 20190337917 - Altman; Michael D. ;   et al. | 2019-11-07 |
Combinations Of Pd-1 Antagonists And Cyclic Dinucleotide Sting Agonists For Cancer Treatment App 20190328762 - Cemerski; Saso ;   et al. | 2019-10-31 |
Sting Agonist Compounds App 20190300513 - Altman; Michael D. ;   et al. | 2019-10-03 |
Compounds useful for altering the levels of bile acids for the treatment of diabetes and cardiometabolic disease Grant 10,414,775 - Caldwell , et al. Sept | 2019-09-17 |
Compound useful for altering the levels of bile acids for the treatment of diabetes and cardiometabolc disease Grant 10,414,774 - Cumming , et al. Sept | 2019-09-17 |
Benzo[b]thiophene compounds as sting agonists Grant 10,414,747 - Altman , et al. Sept | 2019-09-17 |
Compounds Useful For Altering The Levels Of Bile Acids For The Treatment Of Diabetes And Cardiometabolc Disease App 20190218223 - Cumming; Jared N. ;   et al. | 2019-07-18 |
Compounds Useful For Altering The Levels Of Bile Acids For The Treatment Of Diabetes And Cardiometabolc Disease App 20190218224 - Caldwell; John P. ;   et al. | 2019-07-18 |
C5-C6-carbocyclic fused iminothiadiazine dioxides as BACE inhibitors, compositions, and their use Grant 10,329,291 - Scott , et al. | 2019-06-25 |
C5-C6-fused tricyclic iminothiadiazine dioxide compounds as BACE inhibitors, compositions, and their use Grant 10,238,743 - He , et al. | 2019-03-26 |
Compounds For The Treatment Of Malaria App 20190046507 - Khan; Tanweer A. ;   et al. | 2019-02-14 |
C5-C6-Oxacyclic Fused Iminothiadiazine Dioxide Compounds Bearing an Ether Linker as BACE Inhibitors, Compositions, and Their Use App 20190040081 - Walsh; Shawn P. ;   et al. | 2019-02-07 |
C5-C6-Oxacyclic Fused Iminothiazine Dioxide Compounds Bearing an Ether Linker as BACE Inhibitors, Compositions, and Their Use App 20190016734 - Wu; Wen-Lian ;   et al. | 2019-01-17 |
C5-c6-carbocyclic Fused Iminothiadiazine Dioxides As Bace Inhibitors, Compositions, And Their Use App 20180354943 - Scott; Jack D. ;   et al. | 2018-12-13 |
Cyclic di-nucleotide compounds as sting agonists Grant 10,106,574 - Altman , et al. October 23, 2 | 2018-10-23 |
Iminothiadiazine dioxides bearing an amine-linked substituent as BACE inhibitors, compositions, and their use Grant 10,071,998 - Wu , et al. September 11, 2 | 2018-09-11 |
Cyclic Di-nucleotide Compounds As Sting Agonists App 20180244712 - Altman; Michael D. ;   et al. | 2018-08-30 |
Cyclic Di-nucleotide Compounds As Sting Agonists App 20180237469 - Altman; Michael D. ;   et al. | 2018-08-23 |
Cyclic Di-nucleotide Compounds As Sting Agonists App 20180230178 - Altman; Michael D. ;   et al. | 2018-08-16 |
C5-C6-oxacyclic fused iminopyrimidinone compounds as bace inhibitors, compositions, and their use Grant 10,047,098 - Dai , et al. August 14, 2 | 2018-08-14 |
S-imino-S-oxo iminothiazine compounds as bace inhibitors, compositions, and their use Grant 9,957,269 - Cumming , et al. May 1, 2 | 2018-05-01 |
BENZO[b]THIOPHENE COMPOUNDS AS STING AGONISTS App 20180093964 - Altman; Michael D. ;   et al. | 2018-04-05 |
Diazine-fused amidines as BACE inhibitors, compositions, and their use Grant 9,868,738 - Liu , et al. January 16, 2 | 2018-01-16 |
Iminothiadiazine Dioxides Bearing An Amine-linked Substituent As Bace Inhibitors, Compositions, And Their Use App 20170369484 - Wu; Wen-Lian ;   et al. | 2017-12-28 |
C5-c6-oxacyclic Fused Iminopyrimidinone Compounds As Bace Inhibitors, Compositions, And Their Use App 20170362248 - Dai; Xing ;   et al. | 2017-12-21 |
C-6 spirocarbocyclic iminothiadiazine dioxides as BACE inhibitors, compositions, and their use Grant 9,802,928 - Scott , et al. October 31, 2 | 2017-10-31 |
S-imino-s-oxo Iminothiazine Compounds As Bace Inhibitors, Compositions, And Their Use App 20170260181 - Cumming; Jared N. ;   et al. | 2017-09-14 |
Diazine-fused Amidines As Bace Inhibitors, Compositions, And Their Use App 20170247377 - Liu; Kun ;   et al. | 2017-08-31 |
C5-c6-fused Tricyclic Iminothiadiazine Dioxide Compounds As Bace Inhibitors, Compositions, And Their Use App 20170246300 - He; Shuwen ;   et al. | 2017-08-31 |
Iminothiadiazepane dioxide compounds as BACE inhibitors, compositions, and their use Grant 9,745,324 - Dai , et al. August 29, 2 | 2017-08-29 |
C2-carbocyclic iminothiazine dioxides as BACE inhibitors, compositions, and their use Grant 9,732,088 - Walsh , et al. August 15, 2 | 2017-08-15 |
C5-spiro iminothiazine dioxides as BACE inhibitors, compositions, and their use Grant 9,725,468 - Scott , et al. August 8, 2 | 2017-08-08 |
Iminothiadiazine dioxide compounds as BACE inhibitors, compositions, and their use Grant 9,687,494 - Scott , et al. June 27, 2 | 2017-06-27 |
C2-carbocyclic Iminothiazine Dioxides As Bace Inhibitors, Compositions, And Their Use App 20170114065 - Walsh; Shawn P. ;   et al. | 2017-04-27 |
C6-spiro iminothiadiazine dioxides as BACE inhibitors, compositions, and their use Grant 9,580,396 - Cumming , et al. February 28, 2 | 2017-02-28 |
Cyclic Di-nucleotide Compounds As Sting Agonists App 20170044206 - Altman; Michael D. ;   et al. | 2017-02-16 |
Iminothiadiazepane Dioxide Compounds as BACE Inhibitors, Compositions, and Their Use App 20170037056 - Dai; Xing ;   et al. | 2017-02-09 |
Iminothiadiazine Dioxide Compounds As Bace Inhibitors, Compositions, And Their Use App 20160367563 - Scott; Jack D. ;   et al. | 2016-12-22 |
5-substituted iminothiazines and their mono- and dioxides as BACE inhibitors, compositions, and their use Grant 9,499,502 - Wu , et al. November 22, 2 | 2016-11-22 |
C-6 Spirocarbocyclic Iminothiadiazine Dioxides as BACE Inhibitors, Compositions, and Their Use App 20160326155 - Scott; Jack D. ;   et al. | 2016-11-10 |
C6-azaspiro iminothiadiazine dioxides as bace inhibitors, compositions, and their use Grant 9,489,013 - Cumming , et al. November 8, 2 | 2016-11-08 |
Iminothiadiazine dioxide compounds as BACE inhibitors, compositions and their use Grant 9,475,785 - Scott , et al. October 25, 2 | 2016-10-25 |
C2-azaspiro iminothiazine dioxides as BACE inhibitors, compositions, and their use Grant 9,453,034 - Gilbert , et al. September 27, 2 | 2016-09-27 |
Iminothiadiazine dioxides containing a thioamide, amidine, or amide oxime group as BACE inhibitors, compositions, and their use Grant 9,447,085 - Cumming , et al. September 20, 2 | 2016-09-20 |
C6-spiro Iminothiadiazine Dioxides As Bace Inhibitors, Compositions, And Their Use App 20160264538 - Cumming; Jared N. ;   et al. | 2016-09-15 |
S-imino-S-oxo-iminothiadiazine compounds as BACE inhibitors, compositions, and their use Grant 9,428,476 - Khan , et al. August 30, 2 | 2016-08-30 |
Iminothiadiazine dioxide compounds as BACE inhibitors, compositions, and their use Grant 9,428,475 - Scott , et al. August 30, 2 | 2016-08-30 |
S-imino-S-oxo-iminothiazine compounds as BACE inhibitors, compositions, and their use Grant 9,422,255 - Khan , et al. August 23, 2 | 2016-08-23 |
Tricyclic substituted thiadiazine dioxide compounds as BACE inhibitors, compositions and their use Grant 9,422,277 - Gilbert , et al. August 23, 2 | 2016-08-23 |
Tricyclic substituted thiadiazine dioxide compounds as BACE inhibitors, compositions and their use Grant 9,416,129 - Gilbert , et al. August 16, 2 | 2016-08-16 |
C5-spiro Iminothiazine Dioxides As Bace Inhibitors, Compositions, And Their Use App 20160222032 - Scott; Jack D. ;   et al. | 2016-08-04 |
C5, C6 oxacyclic-fused thiazine dioxide compounds as BACE inhibitors, compositions, and their use Grant 9,365,589 - Cumming , et al. June 14, 2 | 2016-06-14 |
C6-azaspiro Iminothiadiazine Dioxides As Bace Inhibitors, Compositions, And Their Use App 20160043774 - Cumming; Jared N. ;   et al. | 2016-02-11 |
C2-azaspiro Iminothiazine Dioxides As Bace Inhibitors, Compositions, And Their Use App 20160016975 - Gilbert; Eric J. ;   et al. | 2016-01-21 |
S-imino-s-oxo-iminothiazine Compounds As Bace Inhibitors, Compositions, And Their Use App 20160016921 - Khan; Tanweer A. ;   et al. | 2016-01-21 |
S-imino-s-oxo-iminothiadiazine Compounds As Bace Inhibitors, Compositions, And Their Use App 20160016923 - Khan; Tanweer A. ;   et al. | 2016-01-21 |
C5-C6 oxacyclic-fused thiadiazine dioxide compounds as BACE inhibitors, compositions, and their use Grant 9,221,839 - Cumming , et al. December 29, 2 | 2015-12-29 |
Iminothiadiazine Dioxides Containing A Thioamide, Amidine, Or Amide Oxime Group As Bace Inhibitors, Compositions, And Their Use App 20150353516 - Cumming; Jared N. ;   et al. | 2015-12-10 |
C2,c6 Oxacyclic-fused Thiazine Dioxide Compounds As Bace Inhibitors, Compositions, And Their Use App 20150344500 - Cumming; Jared N. ;   et al. | 2015-12-03 |
2-spiro-substituted iminothiazines and their mono-and dioxides as bace inhibitors, compositions and their use Grant 9,181,236 - Wu , et al. November 10, 2 | 2015-11-10 |
Iminothiadiazine Dioxide Compounds as BACE Inhibitors, Compositions and Their Use App 20150307465 - Scott; Jack D. ;   et al. | 2015-10-29 |
Tricyclic Substituted Thiadiazine Dioxide Compounds As Bace Inhibitors, Compositions And Their Use App 20150284379 - Gilbert; Eric J. ;   et al. | 2015-10-08 |
Tricyclic Substituted Thiadiazine Dioxide Compounds As Bace Inhibitors, Compositions And Their Use App 20150274716 - Gilbert; Eric J. ;   et al. | 2015-10-01 |
Pyrrolidine-fused thiadiazine dioxide compounds as BACE inhibitors, compositions, and their use Grant 9,145,426 - Stamford , et al. September 29, 2 | 2015-09-29 |
Cyclic amide BACE-1 inhibitors having a benzamide substituent Grant 9,062,007 - Cumming , et al. June 23, 2 | 2015-06-23 |
Iminothiadiazine dioxide compounds as brace inhibitors, compositions, and their use Grant 9,029,362 - Scott , et al. May 12, 2 | 2015-05-12 |
Heterocyclic Aspartyl Protease Inhibitors App 20150105354 - Zhu; Zhaoning ;   et al. | 2015-04-16 |
Iminothiadiazine dioxide compounds as BACE inhibitors, compositions, and their use Grant 8,940,748 - Scott , et al. January 27, 2 | 2015-01-27 |
Iminothiadiazine Dioxide Compounds As Bace Inhibitors, Compositions, And Their Use App 20140296221 - Scott; Jack D. ;   et al. | 2014-10-02 |
Iminothiadiazine Dioxide Compounds As Bace Inhibitors, Compositions, And Their Use App 20140296222 - Scott; Jack D. ;   et al. | 2014-10-02 |
Heterocyclic aspartyl protease inhibitors Grant 8,829,036 - Zhu , et al. September 9, 2 | 2014-09-09 |
Iminothiadiazine Dioxide Compounds As Bace Inhibitors, Compositions, And Their Use App 20140206675 - Scott; Jack D. ;   et al. | 2014-07-24 |
2-spiro-substituted Iminothiazines And Their Mono-and Dioxides As Bace Inhibitors, Compositions And Their Use App 20140200213 - Wu; Wen-Lian ;   et al. | 2014-07-17 |
Heterocyclic aspartyl protease inhibitors Grant 8,778,980 - Zhu , et al. July 15, 2 | 2014-07-15 |
Iminothiadiazine dioxide compounds as BACE inhibitors, compositions and their use Grant 8,729,071 - Scott , et al. May 20, 2 | 2014-05-20 |
Cyclic Amide Bace-1 Inhibitors Having A Benzamide Substituent App 20140128361 - Cumming; Jared N. ;   et al. | 2014-05-08 |
5-substituted Iminothiazines And Their Mono- And Dioxides As Bace Inhibitors, Compositions, And Their Use App 20140128382 - Wu; Wen-Lian ;   et al. | 2014-05-08 |
Heterocyclic aspartyl protease inhibitors Grant 8,691,831 - Zhu , et al. April 8, 2 | 2014-04-08 |
Heterocyclic aspartyl protease inhibitors Grant 8,691,833 - Zhu , et al. April 8, 2 | 2014-04-08 |
Heterocyclic Aspartyl Protease Inhibitors App 20140057910 - Zhu; Zhaoning ;   et al. | 2014-02-27 |
C5-c6 Oxacyclic-fused Thiadiazine Dioxide Compounds As Bace Inhibitors, Compositions, And Their Use App 20140023668 - Cumming; Jared N. ;   et al. | 2014-01-23 |
Pyrrolidine-fused Thiadiazine Dioxide Compounds As Bace Inhibitors, Compositions, And Their Use App 20140023667 - Stamford; Andrew W. ;   et al. | 2014-01-23 |
Aspartyl protease inhibitors Grant 8,629,155 - Wu , et al. January 14, 2 | 2014-01-14 |
Cyclic amine BACE-1 inhibitors having a benzamide substituent Grant 8,623,867 - Cumming , et al. January 7, 2 | 2014-01-07 |
Pentafluorosulfur imino heterocyclic compounds as BACE-1 inhibitors, compositions and their use Grant 8,569,310 - Iserloh , et al. October 29, 2 | 2013-10-29 |
Iminothiadiazine dioxide compounds as bace inhibitors, compositions, and their use Grant 8,563,543 - Scott , et al. October 22, 2 | 2013-10-22 |
Pentafluorosulfur imino heterocyclic compounds as BACE-1 inhibitors, compositions, and their use Grant 8,557,826 - Stamford , et al. October 15, 2 | 2013-10-15 |
Phenyl-substituted 2-imino-3-methyl pyrrolo pyrimidinone compounds as BACE-1 inhibitors, compositions, and their use Grant 8,541,427 - Stamford , et al. September 24, 2 | 2013-09-24 |
Heterocyclic Aspartyl Protease Inhibitors App 20130018066 - Zhu; Zhaoning ;   et al. | 2013-01-17 |
Cyclic Amine Bace-1 Inhibitors Having A Benzamide Substituent App 20130004518 - Cumming; Jared N. ;   et al. | 2013-01-03 |
Heterocyclic Aspartyl Protease Inhibitors App 20120276118 - Zhu; Zhaoning ;   et al. | 2012-11-01 |
Cyclic amine BACE-1 inhibitors having a benzamide substituent Grant 8,278,334 - Cumming , et al. October 2, 2 | 2012-10-02 |
Heterocyclic Aspartyl Protease Inhibitors App 20120231018 - Zhu; Zhaoning ;   et al. | 2012-09-13 |
Heterocyclic Aspartyl Protease Inhibitors App 20120231017 - ZHU; ZHAONING ;   et al. | 2012-09-13 |
Aspartyl Protease Inhibitors App 20120232064 - Wu; Yusheng ;   et al. | 2012-09-13 |
Heterocyclic aspartyl protease inhibitors Grant 8,242,112 - Zhu , et al. August 14, 2 | 2012-08-14 |
Pentafluorosulfur Imino Heterocyclic Compounds As Bace-1 Inhibitors, Compositions And Their Use App 20120195881 - Iserloh; Ulrich ;   et al. | 2012-08-02 |
Iminothiadiazine Dioxide Compounds As Bace Inhibitors, Compositions, And Their Use App 20120189642 - Scott; Jack D. ;   et al. | 2012-07-26 |
Iminothiadiazine Dioxide Compounds As Bace Inhibitors, Compositions And Their Use App 20120183563 - Scott; Jack D. ;   et al. | 2012-07-19 |
Pentafluorosulfur Imino Heterocyclic Compounds As Bace-1 Inhibitors, Compositions, And Their Use App 20120148603 - Stamford; Andrew W. ;   et al. | 2012-06-14 |
Heterocyclic aspartyl protease inhibitors Grant 8,183,252 - Zhu , et al. May 22, 2 | 2012-05-22 |
Heterocyclic aspartyl protease inhibitors Grant 8,178,513 - Zhu , et al. May 15, 2 | 2012-05-15 |
Aspartyl protease inhibitors Grant 8,168,641 - Wu , et al. May 1, 2 | 2012-05-01 |
Heterocyclic Aspartyl Protease Inhibitors App 20110218194 - Zhu; Zhaoning ;   et al. | 2011-09-08 |
Heterocyclic aspartyl protease inhibitors Grant 7,973,067 - Zhu , et al. July 5, 2 | 2011-07-05 |
Phenyl-substituted 2-imino-3-methyl Pyrrolo Pyrimidinone Compounds As Bace-1 Inhibitors, Compositions, And Their Use App 20110110957 - Stamford; Andrew W. ;   et al. | 2011-05-12 |
Heterocyclic Aspartyl Protease Inhibitors App 20100292203 - Zhu; Zhaoning ;   et al. | 2010-11-18 |
Heterocyclic aspartyl protease inhibitors Grant 7,763,609 - Zhu , et al. July 27, 2 | 2010-07-27 |
Cyclic Amine Bace-1 Inhibitors Having A Benzamide Substituent App 20100152138 - Cumming; Jared N. ;   et al. | 2010-06-17 |
Heterocyclic aspartyl protease inhibitors Grant 7,700,603 - Zhu , et al. April 20, 2 | 2010-04-20 |
Cyclic amine BACE-1 inhibitors having a benzamide substituent Grant 7,662,816 - Cumming , et al. February 16, 2 | 2010-02-16 |
Cyclic Amine Bace-1 Inhibitors Having A Heterocyclic Substituent App 20090312341 - Cumming; Jared N. ;   et al. | 2009-12-17 |
Heterocyclic Aspartyl Protease Inhibitors App 20090306047 - Zhu; Zhaoning ;   et al. | 2009-12-10 |
Heterocyclic Aspartyl Protease Inhibitors App 20090258868 - Zhu; Zhaoning ;   et al. | 2009-10-15 |
Cyclic amine BACE-1 inhibitors having a heterocyclic substituent Grant 7,598,250 - Cumming , et al. October 6, 2 | 2009-10-06 |
Heterocyclic aspartyl protease inhibitors Grant 7,592,348 - Zhu , et al. September 22, 2 | 2009-09-22 |
Heterocyclic aspartyl protease inhibitors App 20080200445 - Zhu; Zhaoning ;   et al. | 2008-08-21 |
Aspartyl Protease Inhibitors App 20070287692 - Wu; Yusheng ;   et al. | 2007-12-13 |
Heterocyclic aspartyl protease inhibitors App 20070072852 - Zhu; Zhaoning ;   et al. | 2007-03-29 |
Heterocyclic aspartyl protease inhibitors App 20060111370 - Zhu; Zhaoning ;   et al. | 2006-05-25 |
Cyclic amine bace-1 inhibitors having a benzamide substituent App 20050119227 - Cumming, Jared N. ;   et al. | 2005-06-02 |
Cyclic amine BACE-1 inhibitors having a heterocyclic substituent App 20050043290 - Cumming, Jared N. ;   et al. | 2005-02-24 |