Cragoe, Jr.; Edward J.

Patent Applications and Registrations

Patent applications and USPTO patent grants for Cragoe, Jr.; Edward J..The latest application filed is for "hydroxyl ions as novel therapeutic agents and compounds that modulate these ions, compositions employing these agents, therapeutic methods for using such agents".

Company Profile

0.104.0

Cragoe, Jr.; Edward J. - Nacogdoches TX
Cragoe, Jr.; Edward J. - Lansdale PA

*profile and listings may contain filings by different individuals or companies with the same name. Review application materials to confirm ownership/assignment.

Patent Activity

Patent	Date
Hydroxyl ions as novel therapeutic agents and compounds that modulate these ions, compositions employing these agents, therapeutic methods for using such agents Grant 5,679,711 - Carrell , et al. October 21, 1	1997-10-21
Hydroxyl ions as unique therapeutic agents and compounds that modulate these ions, compositions employing these agents, therapeutic methods for using such agents and processes for preparing them Grant 5,585,391 - Carrell , et al. December 17, 1	1996-12-17
Hydroxyl ions as unique therapeutic agents and processes for preparing them Grant 5,574,050 - Carrell , et al. November 12, 1	1996-11-12
Hydroxyl ions as unique therapeutic agents and compounds that modulate these ions Grant 5,514,808 - Carrell , et al. May 7, 1	1996-05-07
((5,6-dichloro-3-oxo-9,9a-d isubstituted-2,3,9,9a-tetrahydrofluoren-7-yl)oxy)alkanoic acids and alkanimidamides Grant 4,797,391 - Woltersdorf, Jr. , et al. January 10, 1	1989-01-10
(1,2-dichloro-8-oxo-5a-substituted-5a,6,7,8 -tetrahydrodibenzofuran-3-yl)alkanoic acids and alkanimidamides Grant 4,769,370 - Woltersdorf, Jr. , et al. September 6, 1	1988-09-06
Substituted (2,3-dihydro-1-oxo-1H-inden-5-yl)alkanoic acids, their derivatives and their salts Grant 4,754,061 - Cragoe, Jr. , et al. June 28, 1	1988-06-28
Compounds useful in treating sickle cell anemia Grant 4,751,244 - Abraham , et al. June 14, 1	1988-06-14
Method of treating a person for sickle cell anemia Grant 4,731,381 - Abraham , et al. March 15, 1	1988-03-15
(5,6-dichloro-3-oxo-9A-propyl-2,3,9,9A-tetrahydrofluoren-7-yl)alkanoic acids and alkanimidamides Grant 4,731,472 - Pietruszkiewicz , et al. March 15, 1	1988-03-15
(5,6-dichloro-3-oxo-2,3,9,9a-tetrahydrofluoren-7-yl)-alkanoic acids and alkanimidamides bearing novel functional 9a-substituents Grant 4,731,471 - Cragoe, Jr. , et al. March 15, 1	1988-03-15
Compounds useful in treating sickle cell anemia Grant 4,731,473 - Abraham , et al. March 15, 1	1988-03-15
[(5,6-dichloro-3-oxo-2,9a-alkano-2,3,9,9a-tetrahydro-1H-fluoren-7-yl)oxy] alkanoic acids and alkanimidamides Grant 4,731,470 - Pietruszkiewicz , et al. March 15, 1	1988-03-15
Anti-asthmatic tetrazolyl 6H-dibenz-[B,E]-[1,4]-oxathiepin derivatives, compositions, and method of use therefor Grant 4,699,917 - Cragoe, Jr. , et al. October 13, 1	1987-10-13
Substituted-3- (2,3-dihydro-1H-inden-5-yl)-4-hydroxy-1H-pyrrole-2,5-diones, useful for treating persons with gray matter edema Grant 4,634,717 - Cragoe, Jr. , et al. January 6, 1	1987-01-06
Substituted (2,3-dihydro-4-(3-oxo-1-cyclohexen-1-yl)phenoxy) alkanoic acids, their derivatives and their salts Grant 4,625,047 - Cragoe, Jr. , et al. November 25, 1	1986-11-25
Use of substituted-3-(2,3-dihydro-1H-inden-5-yl)-4-hydroxy-1H-pyrrole-2,5-dione s, for treatment of grey matter edema Grant 4,605,663 - Cragoe, Jr. , et al. August 12, 1	1986-08-12
[(2,3,9,9a-tetrahydro-3-oxo-9a-substituted-1H-fluoren-7-yl)oxy]ethanimida mides and [(2,3,9,9a-tetrahydro-3-oxo-9a-substituted-1H-fluoren-7-yl)oxy]ethanimid ic acid hydrazides, their derivatives and their salts Grant 4,604,396 - Cragoe, Jr. , et al. August 5, 1	1986-08-05
Treatment of gray matter edema with 3-(2,3-dihydro-1H-inden-5-yl)-4-hydroxy-1H-pyrrole-2,5-diones Grant 4,596,821 - Cragoe, Jr. , et al. June 24, 1	1986-06-24
Substituted pyranone inhibitors of cholesterol synthesis Grant 4,567,289 - Willard , et al. * January 28, 1	1986-01-28
4-Substituted-3-hydroxy-3-pyrroline-2,5-dione inhibitors of glycolic acid oxidase Grant 4,537,902 - Cragoe, Jr. , et al. August 27, 1	1985-08-27
Treatment of gray matter edema Grant 4,463,208 - Cragoe, Jr. , et al. July 31, 1	1984-07-31
Substituted pyranone inhibitors of cholesterol synthesis Grant 4,459,422 - Willard , et al. July 10, 1	1984-07-10
Pharmaceutical compositions of novel substituted pyrazinyl-1,2,4-oxadiazoles useful in the treatment of edema and hypertension Grant 4,454,132 - Bock , et al. June 12, 1	1984-06-12
4-Naphthyl and substituted naphthyl-3-hydroxy-3-pyrroline-2,5-diones and their use as inhibitors of glycolic acid oxidase Grant 4,448,786 - Cragoe, Jr. , et al. May 15, 1	1984-05-15
4-[5(and 4)-Substituted-2-thienyl]-3-hydroxy-3-pyrroline-2,5-dione inhibitors of glycolic acid oxidase Grant 4,432,992 - Cragoe, Jr. , et al. February 21, 1	1984-02-21
4-Alkylsubstituted-3-hydroxy-3-pyrroline-2,5-dione inhibitors of glycolic acid oxidase Grant 4,428,959 - Cragoe, Jr. , et al. January 31, 1	1984-01-31
10,11-Dihydro-11-oxodibenzo[b,f]thiepin compounds Grant 4,394,515 - Rokach , et al. July 19, 1	1983-07-19
1-(Substituted-aminoalkoxyphenyl)-2-methylene-1-alkanones, compositions and use Grant 4,390,537 - Cragoe, Jr. June 28, 1	1983-06-28
Treatment of gray matter edema Grant 4,389,417 - Bourke , et al. June 21, 1	1983-06-21
4-(Substituted thiazolyl)-3-hydroxy-3-pyrroline-2,5-dione inhibitors of glycolic acid oxidase Grant 4,379,791 - Cragoe, Jr. , et al. * April 12, 1	1983-04-12
4-(Substituted thiazolyl)-3-hydroxy-3-pyrroline-2,5-dione inhibitors of glycolic acid oxidase Grant 4,377,588 - Cragoe, Jr. , et al. March 22, 1	1983-03-22
[5,6,9A-Substituted-3-oxo-1,2,9,9a-tetrahydro-3H-fluoren-7-yl)oxy]alkanoi c and cycloalkanoic acids, their analogs, esters, salts, and derivatives Grant 4,356,314 - Cragoe, Jr. , et al. October 26, 1	1982-10-26
1-(Substituted-aminoalkoxyphenyl)-2-methylene-1-alkanones, compositions and use thereof Grant 4,342,782 - Cragoe, Jr. August 3, 1	1982-08-03
4-Substituted-3-hydroxy-3-pyrroline-2,5-dione inhibitors of glycolic acid oxidase Grant 4,342,776 - Cragoe, Jr. , et al. August 3, 1	1982-08-03
2,4-Dioxo-4-substituted-1-butanoic acid derivatives useful in treating urinary tract calcium oxalate lithiasis Grant 4,337,258 - Rooney , et al. June 29, 1	1982-06-29
2,4-Dioxo-4-substituted-1-butanoic acid derivatives useful in treating urinary tract calcium oxalate lithiasis Grant 4,336,397 - Cragoe, Jr. , et al. June 22, 1	1982-06-22
[(5,6,9a-Substituted-3-oxo-1,2,9,9a-tetrahy dro-3H-fluoren-7-yl)oxy]alkanoic and cycloalkanoic acids and their analogs, esters, salts and derivatives Grant 4,317,922 - Cragoe, Jr. , et al. March 2, 1	1982-03-02
Substituted pyrazinyl-1,2,4-oxadiazoles Grant 4,309,540 - Bock , et al. January 5, 1	1982-01-05
4-(Substituted phenyl thiazolyl)-3-hydroxy-3-pyrroline-2,5-diones Grant 4,298,743 - Cragoe, Jr. , et al. November 3, 1	1981-11-03
2,3-Dihydro-6,7-disubstituted-5-(acyl)benzofuran-2-carboxylic acids Grant 4,296,122 - Cragoe, Jr. , et al. October 20, 1	1981-10-20
4-(Pyridyl, piperazinyl and thiazolyl substituted thiazolyl)-3-hydroxy-3-pyrroline-2,5-diones Grant 4,296,237 - Cragoe, Jr. , et al. October 20, 1	1981-10-20
Dibenz[b,e]oxepin compounds Grant 4,282,365 - Rokach , et al. August 4, 1	1981-08-04
Process for preparing 2,3-substituted-1,2,-isothiazolium salt antimicrobials Grant 4,267,341 - Rokach , et al. May 12, 1	1981-05-12
10,11-Dihydrodibenzo[b,f][1,4]thiazepine carboxylic acids esters and amides thereof Grant 4,263,207 - Rokach , et al. April 21, 1	1981-04-21
Interphenylene 9-thia-11-oxo-12-azaprostanoic acid compounds Grant 4,260,771 - Cragoe, Jr. , et al. April 7, 1	1981-04-07
4-Substituted-3-hydroxy-3-pyrroline-2,5-dione inhibitors of glycolic acid oxidase Grant 4,256,758 - Cragoe, Jr. , et al. March 17, 1	1981-03-17
Indanacetic acid compounds Grant 4,249,021 - Cragoe, Jr. , et al. February 3, 1	1981-02-03
Heterocyclic substituted pyrazinoylguanidines Grant 4,246,406 - Cragoe, Jr. , et al. January 20, 1	1981-01-20
2,3-Dihydro-6,7-disubstituted-5-(substituted sulfonyl)benzofuran-2-carboxylic acids Grant 4,237,130 - Cragoe, Jr. , et al. December 2, 1	1980-12-02
3,3-Substituted spiro-1,2,4-benzothiadiazines Grant 4,226,867 - Cragoe, Jr. , et al. October 7, 1	1980-10-07
Interphenylene 9-thia-11-oxo-12-aza-prostanoic acids Grant 4,225,609 - Cragoe, Jr. , et al. Sept	1980-09-30
Substituted 2,2-dioxo-1,2,3-benzoxathiazines Grant 4,221,790 - Cragoe, Jr. , et al. September 9, 1	1980-09-09
Cyclic imidazole cyanoguanidines Grant 4,220,654 - Bolhofer , et al. September 2, 1	1980-09-02
N-Pyrazinecarbonyl-N'-alkoxycarbonyl and N',N"-bis(alkoxycarbonyl)guanidines and processes for preparing same Grant 4,208,413 - Cragoe, Jr. , et al. June 17, 1	1980-06-17
Derivatives of glycolic and glyoxylic acid as inhibitors of glycolic acid oxidase Grant 4,207,329 - Williams , et al. June 10, 1	1980-06-10
6-Substituted amiloride derivatives Grant 4,196,292 - Woltersdorf, Jr. , et al. April 1, 1	1980-04-01
2,3-Dihydro-5-thienylmethyl and furylmethyl-6-substituted and 6,7-disubstituted-benzofuran-2-carboxylic acid Grant 4,189,496 - Cragoe, Jr. , et al. * February 19, 1	1980-02-19
Tetrazole derivatives of [1-oxo-2-aryl or thienyl-2-substituted-5-indanyloxy(or thio)]alkanoic acids Grant 4,182,764 - Cragoe, Jr. , et al. January 8, 1	1980-01-08
2,3-Dihydro-6,7-disubstituted-5-acyl benzofuran-2-carboxylic acids Grant 4,181,727 - Cragoe, Jr. , et al. January 1, 1	1980-01-01
Inhibitors of glycolic acid oxidase Grant 4,178,386 - Williams , et al. December 11, 1	1979-12-11
[1-Oxo-2-thienyl-2-substituted-5-indanyloxy (or thio)]alkanoic acids and derivatives thereof Grant 4,177,285 - Cragoe, Jr. , et al. December 4, 1	1979-12-04
Substituted 2,2-dioxo-1,2,3-benzoxathiazines Grant 4,166,177 - Cragoe, Jr. , et al. August 28, 1	1979-08-28
Nuclear substituted 2-hydroxyphenylmethanesulfamic acids Grant 4,159,279 - Smith , et al. June 26, 1	1979-06-26
Certain 5-substituted or unsubstituted phenyl or furyl benzofuran 2-carboxylic acids Grant 4,154,742 - Cragoe, Jr. , et al. May 15, 1	1979-05-15
N-pyrazinecarbonyl-N'-acylguanidines Grant 4,140,776 - Cragoe, Jr. , et al. February 20, 1	1979-02-20
Substituted naphthyridinones Grant 4,133,885 - Bolhofer , et al. January 9, 1	1979-01-09
Interphenylene 8-aza-9-dioxothia-11,12-secoprostaglandins Grant 4,112,236 - Bicking , et al. September 5, 1	1978-09-05
3-Thiazolidinyl heptanoic acids Grant 4,102,888 - Smith , et al. July 25, 1	1978-07-25
11,12-Secoprostaglandins Grant 4,092,356 - Cragoe, Jr. , et al. May 30, 1	1978-05-30
8-Aza-9-oxo(and dioxo)-thia-11,12-secoprostaglandins Grant 4,091,107 - Cragoe, Jr. , et al. May 23, 1	1978-05-23
2,3-Dihydro-6,7-disubstituted-5-acyl benzofuran-2-carboxylic acids Grant 4,087,542 - Cragoe, Jr. , et al. May 2, 1	1978-05-02
6,7-Disubstituted-5-(acyl)benzofuran-2-carboxylic acids Grant 4,085,117 - Cragoe, Jr. , et al. April 18, 1	1978-04-18
Pyrazinecarboxamides and processes for preparing same Grant 4,085,211 - Cragoe, Jr. , et al. April 18, 1	1978-04-18
1-Oxo-2,2-disubstituted-5-indanyloxy(or thio)alkanoic acids Grant 4,085,219 - Cragoe, Jr. , et al. April 18, 1	1978-04-18
1-Oxo-2,2-disubstituted-5-indanyloxy(or thio)alkano acids Grant 4,081,554 - Cragoe, Jr. , et al. March 28, 1	1978-03-28
[1-Oxo-2-halo(or hydrogen) indanyloxy]-alkanoic acid Grant 4,070,539 - Cragoe, Jr. , et al. January 24, 1	1978-01-24
Spirobenzoxazinium salts, method of use and compositions thereof as antihypertensive agents Grant 4,067,980 - Cragoe, Jr. , et al. January 10, 1	1978-01-10
11,12-Secoprostaglandins Grant 4,066,692 - Cragoe, Jr. , et al. January 3, 1	1978-01-03
8-Halo-11,12-secoprostaglandins Grant 4,059,601 - Cragoe, Jr. , et al. November 22, 1	1977-11-22
Dihydro- and tetrahydro- iminothiazines Grant 4,054,652 - Rooney , et al. October 18, 1	1977-10-18
Antiinflammatory 2-aminomethyl-6-trihalomethylphenols Grant 4,044,153 - Schultz , et al. * August 23, 1	1977-08-23
8-Aza-9-oxo(and dioxo)-thia-11,12-secoprostaglandins Grant 4,033,996 - Cragoe, Jr. , et al. July 5, 1	1977-07-05
Substituted 2-aminomethyl-6-iodophenols Grant 4,029,816 - Cragoe, Jr. , et al. June 14, 1	1977-06-14
Method of treatment with 2-iminothiazolidines and thiazolines Grant 4,029,803 - Hunter , et al. June 14, 1	1977-06-14
Novel analogs of prostaglandins with 4-oxo-thiazolidinyl nucleus and method of preparation thereof Grant 4,022,794 - Smith , et al. May 10, 1	1977-05-10
[1,3-Dihydroxy-2-substituted and 2,2-disubstituted-indanyloxy(or thio)]alkanoic acids Grant 4,006,180 - Cragoe, Jr. , et al. February 1, 1	1977-02-01
8-Halo-11,12-secoprostaglandins Grant 3,991,087 - Cragoe, Jr. , et al. November 9, 1	1976-11-09
16-Ethers of 8-aza-9-dioxothia-11,12-seco-prostaglandins Grant 3,991,106 - Cragoe, Jr. , et al. November 9, 1	1976-11-09
11,12-Secoprostaglandins Grant 3,989,749 - Cragoe, Jr. , et al. November 2, 1	1976-11-02
11,12-Secoprostaglandins Grant 3,987,091 - Cragoe, Jr. , et al. October 19, 1	1976-10-19
6-Oxo-7-substituted and 7,7-disubstituted-6H-indeno-[5,4-b]furan (and thiophene) carboxylic acids Grant 3,984,552 - Cragoe, Jr. , et al. October 5, 1	1976-10-05
[1-Oxo-2,3-hydrocarbylene-5-indanyloxy(or thio)]alkanoic acids Grant 3,976,686 - Cragoe, Jr. , et al. August 24, 1	1976-08-24
[1,3-Dioxo-2-substituted and 2,2-disubstituted- indanyloxy (or thio] alkanoic acids Grant 3,976,681 - Cragoe, Jr. , et al. August 24, 1	1976-08-24
[1-Hydroximino-2,2-disubstituted-5-indanyloxy-(or thio)]alkanoic acids Grant 3,974,212 - Cragoe, Jr. , et al. August 10, 1	1976-08-10
Pharmaceutical compositions and method of treatment employing 1,3-dioxo-2,2-disubstituted indanyloxy alkanoic acids Grant 3,966,966 - Cragoe, Jr. , et al. June 29, 1	1976-06-29
Phenoxyacetic acid derivatives as uricosuric agents Grant 3,958,004 - Cragoe, Jr. , et al. May 18, 1	1976-05-18
6-Oxo-7-substituted-6H-indeno-[5,4-b]furan(and thiophene)-carboxylic acids Grant 3,931,239 - Cragoe, Jr. , et al. January 6, 1	1976-01-06
Indanacetic acid compounds Grant 3,929,872 - Cragoe, Jr. , et al. December 30, 1	1975-12-30
Phenol compounds in treating pain, fever and inflammation Grant 3,928,624 - Cragoe, Jr. , et al. December 23, 1	1975-12-23
5-Oxo-6-substituted-cyclopent-[f]-indole-2-carboxylic acids Grant 3,914,253 - Cragoe, Jr. , et al. October 21, 1	1975-10-21
Aryl-oxo-alkanoic acids Grant 3,894,065 - Cragoe, Jr. , et al. July 8, 1	1975-07-08
Methods Of Treating Edema And Hypertension Using Certain 2-aminoethylphenols Grant 3,794,734 - Cragoe, Jr. , et al. February 26, 1	1974-02-26
Substituted 1-oxoinden-5-yloxy Alkanoic Acids Grant 3,668,241 - Cragoe, Jr. , et al. June 6, 1	1972-06-06

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