| Patent | Date |
|---|
Nucleotide mimics and their prodrugs
Grant 7,807,653 - Cook , et al. October 5, 2 | 2010-10-05 |
Nucleotide mimics and their prodrugs
Grant 7,598,230 - Cook , et al. October 6, 2 | 2009-10-06 |
Nucleotide mimics and their prodrugs
App 20070265224 - Cook; Phillip D. ; et al. | 2007-11-15 |
Nucleotide mimics and their prodrugs
App 20070259832 - Cook; Phillip D. ; et al. | 2007-11-08 |
Nucleotide mimics and their prodrugs
Grant 7,285,658 - Cook , et al. October 23, 2 | 2007-10-23 |
Nucleoside 5'-monophosphate mimics and their prodrugs
App 20040023901 - Cook, Phillip D. ; et al. | 2004-02-05 |
Monomeric diols, phosphate linked oligomers formed therefrom and processes for preparing
App 20030065146 - Cook, Phillip D. ; et al. | 2003-04-03 |
Oligonucleotide mimics having nitrogen-containing linkages
Grant 6,271,357 - Cook , et al. August 7, 2 | 2001-08-07 |
Oligonucleotide mimics having nitrogen-containing linkages
Grant 5,783,682 - Cook , et al. July 21, 1 | 1998-07-21 |
Phosphoramidate and phosphorothioamidate oligomeric compounds
Grant 5,637,684 - Cook , et al. June 10, 1 | 1997-06-10 |
Compounds having phosphorodithioate linkages of high chiral purity
Grant 5,635,488 - Cook , et al. June 3, 1 | 1997-06-03 |
Method for removing unreacted electrophiles from a reaction mixture
Grant 5,632,898 - Jung , et al. May 27, 1 | 1997-05-27 |
Gapped 2' modified oligonucleotides
Grant 5,623,065 - Cook , et al. April 22, 1 | 1997-04-22 |
Heteroatomic oligonucleoside linkages
Grant 5,623,070 - Cook , et al. April 22, 1 | 1997-04-22 |
Oligonucleotides for modulating protein kinase C having phosphorothioate linkages of high chiral purity
Grant 5,620,963 - Cook , et al. April 15, 1 | 1997-04-15 |
Backbone-modified oligonucleotide analogs and preparation thereof through radical coupling
Grant 5,618,704 - Sanghvi , et al. April 8, 1 | 1997-04-08 |
Process for preparing oligonucleotides using silyl-containing diamino phosphorous reagents
Grant 5,614,621 - Ravikumar , et al. March 25, 1 | 1997-03-25 |
Backbone modified oligonucleotide analogues
Grant 5,610,289 - Cook , et al. March 11, 1 | 1997-03-11 |
Conjugated 4'-desmethyl nucleoside analog compounds
Grant 5,608,046 - Cook , et al. March 4, 1 | 1997-03-04 |
Oligonucleotides for modulating cytomegalovirus having phosphorothioate linkages of high chiral purity
Grant 5,607,923 - Cook , et al. March 4, 1 | 1997-03-04 |
Backbone modified oligonucleotide analogs
Grant 5,602,240 - De Mesmaeker , et al. February 11, 1 | 1997-02-11 |
Oligonucleotides having phosphorothioate linkages of high chiral purity
Grant 5,599,797 - Cook , et al. February 4, 1 | 1997-02-04 |
Oligonucleotides containing N-2 substituted purines
Grant 5,587,469 - Cook , et al. December 24, 1 | 1996-12-24 |
Method of making oligonucleotide libraries
Grant 5,587,471 - Cook , et al. December 24, 1 | 1996-12-24 |
Oligonucleotides having phosphorothioate linkages of high chiral purity
Grant 5,587,361 - Cook , et al. December 24, 1 | 1996-12-24 |
Thiol-derivatized nucleosides
Grant 5,578,718 - Cook , et al. November 26, 1 | 1996-11-26 |
Oligonucleotides for modulating hepatitis C virus having phosphorothioate linkages of high chiral purity
Grant 5,576,302 - Cook , et al. November 19, 1 | 1996-11-19 |
Covalently cross-linked oligonucleotides
Grant 5,543,507 - Cook , et al. August 6, 1 | 1996-08-06 |
Backbone modified oligonucleotide analogs and solid phase synthesis thereof
Grant 5,541,307 - Cook , et al. July 30, 1 | 1996-07-30 |
Peptide nucleic acid combinatorial libraries and improved methods of synthesis
Grant 5,539,083 - Cook , et al. July 23, 1 | 1996-07-23 |
Process for preparing oligonucleotides having chiral phosphorus linkages
Grant 5,521,302 - Cook May 28, 1 | 1996-05-28 |
Compositions for inhibiting RNA activity
Grant 5,514,786 - Cook , et al. May 7, 1 | 1996-05-07 |
Oligonucleotides with substantially chirally pure phosphorothioate linkages
Grant 5,506,212 - Hoke , et al. April 9, 1 | 1996-04-09 |
Oligonucleoside linkages containing adjacent oxygen and nitrogen atoms
Grant 5,489,677 - Sanghvi , et al. February 6, 1 | 1996-02-06 |
Backbone modified oligonucleotide analogs and preparation thereof through reductive coupling
Grant 5,386,023 - Sanghvi , et al. January 31, 1 | 1995-01-31 |
Compounds useful in the synthesis of nucleic acids capable of cleaning RNA
Grant 5,359,051 - Cook , et al. October 25, 1 | 1994-10-25 |
Cyclobutyl oligonucleotide surrogates
Grant 5,359,044 - Cook , et al. October 25, 1 | 1994-10-25 |
Monomers for preparation of oligonucleotides having chiral phosphorus linkages
Grant 5,212,295 - Cook May 18, 1 | 1993-05-18 |
Deoxyadenosine compounds and methods of making and using the same
Grant 4,908,441 - Cook , et al. March 13, 1 | 1990-03-13 |
Methods of using 2-chloro-2'-deoxyadenosine-5'-phosphate and its salts
Grant 4,826,823 - Cook , et al. May 2, 1 | 1989-05-02 |
Compound 2-iodo-2'-deoxyadenosine
Grant 4,719,295 - Cook , et al. January 12, 1 | 1988-01-12 |
4-amino-3-halo-2-pyridinone nucleoside and nucleotide compounds
Grant 4,681,873 - McNamara , et al. July 21, 1 | 1987-07-21 |
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