Patent | Date |
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Indazole compounds as MGLUR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction Grant 11,427,573 - Conn , et al. August 30, 2 | 2022-08-30 |
Indazole Compounds As Mglur4 Allosteric Potentiators, Compositions, And Methods Of Treating Neurological Dysfunction App 20220259190 - Conn; P. Jeffrey ;   et al. | 2022-08-18 |
Antagonists Of The Muscarinic Acetylcholine Receptor M4 App 20220213069 - Lindsley; Craig W. ;   et al. | 2022-07-07 |
Positive allosteric modulators of the muscarinic acetylcholine receptor M4 Grant 11,376,254 - Lindsley , et al. July 5, 2 | 2022-07-05 |
Antagonists of the muscarinic acetylcholine receptor M.sub.4 Grant 11,352,344 - Lindsley , et al. June 7, 2 | 2022-06-07 |
Antagonists of the muscarinic acetylcholine receptor M4 Grant 11,325,896 - Lindsley , et al. May 10, 2 | 2022-05-10 |
Pyridine quinoline compounds as MGLUR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction Grant 11,319,304 - Conn , et al. May 3, 2 | 2022-05-03 |
Antagonists of the muscarinic acetylcholine receptor M4 Grant 11,299,481 - Lindsley , et al. April 12, 2 | 2022-04-12 |
Antagonists Of The Muscarinic Acetylcholine Receptor M4 App 20220048913 - Lindsley; Craig W. ;   et al. | 2022-02-17 |
Positive Allosteric Modulators Of The Muscarinic Acetylcholine Receptor M1 App 20220041606 - Lindsley; Craig W. ;   et al. | 2022-02-10 |
Isoquinoline amine compounds as mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction Grant 11,242,342 - Conn , et al. February 8, 2 | 2022-02-08 |
Substituted octahydropyrrolo[3,4-b]pyrroles as antagonists of the muscarinic acetylcholine receptor M4 Grant 11,225,484 - Lindsley , et al. January 18, 2 | 2022-01-18 |
Positive Allosteric Modulators Of The Muscarinic Acetylcholine Receptor M1 App 20210355114 - Lindsley; Craig W. ;   et al. | 2021-11-18 |
Antagonists of the muscarinic acetylcholine receptor M4 Grant 11,149,022 - Lindsley , et al. October 19, 2 | 2021-10-19 |
Positive allosteric modulators of the muscarinic acetylcholine receptor M4 Grant 11,142,532 - Lindsley , et al. October 12, 2 | 2021-10-12 |
Positive allosteric modulators of the muscarinic acetylcholine receptor M.sub.1 Grant 11,111,251 - Lindsley , et al. September 7, 2 | 2021-09-07 |
Positive Allosteric Modulators Of The Muscarinic Acetylcholine Receptor M1 App 20210261526 - Lindsley; Craig W. ;   et al. | 2021-08-26 |
Positive Allosteric Modulators Of The Muscarinic Acetylcholine Receptor M1 App 20210230180 - Lindsley; Craig W. ;   et al. | 2021-07-29 |
Antagonists Of The Muscarinic Acetylcholine Receptor M4 App 20210188811 - Lindsley; Craig W. ;   et al. | 2021-06-24 |
Antagonists Of The Muscarinic Acetylcholine Receptor M4 App 20210188820 - Lindsley; Craig W. ;   et al. | 2021-06-24 |
Positive allosteric modulators of the muscarinic acetylcholine receptor M4 Grant 11,008,335 - Lindsley , et al. May 18, 2 | 2021-05-18 |
Positive Allosteric Modulators Of The Muscarinic Acetylcholine Receptor M1 App 20210130348 - Lindsley; Craig W. ;   et al. | 2021-05-06 |
Isoquinoline ether compounds as mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction Grant 10,968,227 - Conn , et al. April 6, 2 | 2021-04-06 |
Positive allosteric modulators of the muscarinic acetylcholine receptor M4 Grant 10,961,253 - Lindsley , et al. March 30, 2 | 2021-03-30 |
Positive allosteric modulators of the muscarinic acetylcholine receptor M.sub.4 Grant 10,934,276 - Lindsley , et al. March 2, 2 | 2021-03-02 |
Positive allosteric modulators of the muscarinic acetylcholine receptor M4 Grant 10,927,126 - Lindsley , et al. February 23, 2 | 2021-02-23 |
Positive allosteric modulators of the muscarinic acetylcholine receptor M1 Grant 10,899,759 - Lindsley , et al. January 26, 2 | 2021-01-26 |
Antagonists Of The Muscarinic Acetylcholine Receptor M4 App 20200392117 - Lindsley; Craig W. ;   et al. | 2020-12-17 |
Antagonists Of The Muscarinic Acetylcholine Receptor M4 App 20200369666 - Lindsley; Craig W. ;   et al. | 2020-11-26 |
Antagonists Of The Muscarinic Acetylcholine Receptor M4 App 20200369650 - Lindsley; Craig W. ;   et al. | 2020-11-26 |
Antagonists Of The Muscarinic Acetylcholine Receptor M4 App 20200339547 - Lindsley; Craig W. ;   et al. | 2020-10-29 |
Positive Allosteric Modulators Of The Muscarinic Acetylcholine Receptor M4 App 20200323857 - Lindsley; Craig W. ;   et al. | 2020-10-15 |
Indazole Compounds As Mglur4 Allosteric Potentiators, Compositions, And Methods Of Treating Neurological Dysfunction App 20200291019 - Conn; P. Jeffrey ;   et al. | 2020-09-17 |
Positive allosteric modulators of the muscarinic acetylcholine receptor M4 Grant 10,736,898 - Lindsley , et al. A | 2020-08-11 |
Substituted 2-(4-heterocyclylbenzyl)isoindolin-1-one Analogs As Positive Allosteric Modulators Of The Muscarinic Acetylcholine R App 20200231592 - Lindsley; Craig W. ;   et al. | 2020-07-23 |
Isoquinoline amide and isoquinoline amide-substituted compounds as mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction Grant 10,710,997 - Conn , et al. | 2020-07-14 |
Positive Allosteric Modulators Of The Muscarinic Acetylcholine Receptor M4 App 20200181166 - Lindsley; Craig W. ;   et al. | 2020-06-11 |
Pyridine Quinoline Compounds As Mglur4 Allosteric Potentiators, Compositions, And Methods Of Treating Neurological Dysfunction App 20200165232 - Conn; P. Jeffrey ;   et al. | 2020-05-28 |
Substituted 2-(4-heterocyclylbenzyl)isoindolin-1-one analogs as positive allosteric modulators of the muscarinic acetylcholine receptor M1 Grant 10,654,847 - Lindsley , et al. | 2020-05-19 |
Positive Allosteric Modulators Of The Muscarinic Acetylcholine Receptor M1 App 20200131159 - Lindsley; Craig W. ;   et al. | 2020-04-30 |
Positive Allosteric Modulators Of The Muscarinic Acetylcholine Receptor M1 App 20200131180 - Lindsley; Craig W. ;   et al. | 2020-04-30 |
Positive Allosteric Modulators Of The Muscarinic Acetylcholine Receptor M4 App 20200079756 - Lindsley; Craig W. ;   et al. | 2020-03-12 |
Positive Allosteric Modulators Of The Muscarinic Acetylcholine Receptor M1 App 20200024275 - Lindsley; Craig W. ;   et al. | 2020-01-23 |
4,5-substituted picolinamide and picolinonitrile metabotropic glutamate receptor 2 negative allosteric modulators Grant 10,538,491 - Conn , et al. Ja | 2020-01-21 |
Indazole and azaindazole substituted compounds as mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction Grant 10,526,323 - Conn , et al. J | 2020-01-07 |
Indazole compounds as mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction Grant 10,508,105 - Conn , et al. Dec | 2019-12-17 |
Isoquinoline Amine Compounds As Mglur4 Allosteric Potentiators, Compositions, And Methods Of Treating Neurological Dysfunction App 20190367506 - Conn; P. Jeffrey ;   et al. | 2019-12-05 |
Isoquinoline Ether Compounds As Mglur4 Allosteric Potentiators, Compositions, And Methods Of Treating Neurological Dysfunction App 20190359615 - Conn; P. Jeffrey ;   et al. | 2019-11-28 |
Positive Allosteric Modulators Of The Muscarinic Acetylcholine Receptor M4 App 20190330225 - Lindsley; Craig W. ;   et al. | 2019-10-31 |
Positive Allosteric Modulators Of The Muscarinic Acetylcholine Receptor M1 App 20190330226 - Lindsley; Craig W. ;   et al. | 2019-10-31 |
Positive Allosteric Modulators Of The Muscarinic Acetylcholine Receptor M4 App 20190330231 - Lindsley; Craig W. ;   et al. | 2019-10-31 |
Negative allosteric modulators of metabotropic glutamate receptor 3 Grant 10,399,948 - Conn , et al. Sep | 2019-09-03 |
Positive allosteric modulators of the muscarinic acetylcholine receptor M4 Grant 10,342,782 - Lindsley , et al. July 9, 2 | 2019-07-09 |
Positive Allosteric Modulators Of The Muscarinic Acetylcholine Receptor M4 App 20190167688 - Lindsley; Craig W. ;   et al. | 2019-06-06 |
Positive Allosteric Modulators Of The Muscarinic Acetylcholine Receptor M4 App 20190161498 - Lindsley; Craig W. ;   et al. | 2019-05-30 |
Benzomorpholine and benzomorpholine-substituted compounds as MGLUR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction Grant 10,294,222 - Conn , et al. | 2019-05-21 |
Positive allosteric modulators of the muscarinic acetylcholine receptor M4 Grant 10,239,887 - Lindsley , et al. | 2019-03-26 |
Isoquiniline and napthalene-substituted compounds as mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction Grant 10,227,343 - Conn , et al. | 2019-03-12 |
Substituted pyrrolo[3,4-e]indolizines, imidazo[1,2-a]pyrrolo[3,4-e]pyridines, pyrrolo[3,4-e][1,2,4]triazolo[1,5-a]pyridines and pyrrolo[3,4-e][1,2,4]triazolo[4,3-a]pyridines as positive allosteric modulators of muscarinic acetylcholine receptor M1 Grant 10,221,175 - Conn , et al. | 2019-03-05 |
Benzothiazole and benzisothiazole-substituted compounds as mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction Grant 10,221,172 - Conn , et al. | 2019-03-05 |
Indazole Compounds As Mglur4 Allosteric Potentiators, Compositions, And Methods Of Treating Neurological Dysfunction App 20190055225 - Conn; P. Jeffrey ;   et al. | 2019-02-21 |
Positive allosteric modulators of the muscarinic acetylcholine receptor M.sub.4 Grant 10,189,857 - Lindsley , et al. Ja | 2019-01-29 |
Substituted 2-(4-heterocyclylbenzyl)isoindolin-1-one Analogs As Positive Allosteric Modulators Of The Muscarinic Acetylcholine Receptor M1 App 20180179205 - Lindsley; Craig W. ;   et al. | 2018-06-28 |
Benzoisoxazole-substituted compounds as MGLUR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction Grant 9,980,945 - Conn , et al. May 29, 2 | 2018-05-29 |
Substituted Imidazopyridine And Triazolopyridine Analogs As Positive Allosteric Modulators Of Muscarinic Acetylcholine Receptor M1 App 20180118746 - Conn; P. Jeffrey ;   et al. | 2018-05-03 |
Positive Allosteric Modulators Of The Muscarinic Acetylcholine Receptor M4 App 20180086776 - Lindsley; Craig W. ;   et al. | 2018-03-29 |
Negative Allosteric Modulators Of Metabotropic Glutamate Receptor 2 App 20180072674 - Conn; P. Jeffrey ;   et al. | 2018-03-15 |
Benzomorpholine And Benzomorpholine-substituted Compounds As Mglur4 Allosteric Potentiators, Compositions, And Methods Of Treating Neurological Dysfunction App 20180057490 - Conn; P. Jeffrey ;   et al. | 2018-03-01 |
Isoquinoline Amide And Isoquinoline Amide-substituted Compounds As Mglur4 Allosteric Potentiators, Compositions, And Methods Of Treating Neurological Dysfunction App 20180057491 - Conn; P. Jeffrey ;   et al. | 2018-03-01 |
Positive Allosteric Modulators Of The Muscarinic Acetylcholine Receptor M4 App 20180028501 - Lindsley; Craig W. ;   et al. | 2018-02-01 |
Isoquiniline And Napthalene-substituted Compounds As Mglur4 Allosteric Potentiators, Compositions, And Methods Of Treating Neurological Dysfunction App 20180022745 - Conn; P. Jeffrey ;   et al. | 2018-01-25 |
Negative Allosteric Modulators Of Metabotropic Glutamate Receptor 3 App 20180022712 - Conn; P. Jeffrey ;   et al. | 2018-01-25 |
Benzoisoxazole-substituted Compounds As Mglur4 Allosteric Potentiators, Compositions, And Methods Of Treating Neurological Dysfunction App 20180021312 - Conn; P. Jeffrey ;   et al. | 2018-01-25 |
Benzothiazole And Benzisothiazole-substituted Compounds As Mglur4 Allosteric Potentiators, Compositions, And Methods Of Treating Neurological Dysfunction App 20180022744 - Conn; P. Jeffrey ;   et al. | 2018-01-25 |
Indazole And Azaindazole Substituted Compounds As Mglur4 Allosteric Potentiators, Compositions, And Methods Of Treating Neurological Dysfunction App 20180022746 - Conn; P. Jeffrey ;   et al. | 2018-01-25 |
Substituted 5-aminothieno[2,3-C]pyridazine-6-carboxamide analogs as positive allosteric modulators of the muscarinic acetylcholine receptor M4 Grant 9,868,746 - Lindsley , et al. January 16, 2 | 2018-01-16 |
Positive Allosteric Modulators Of The Muscarinic Acetylcholine Receptor M4 App 20170369505 - Lindsley; Craig W. ;   et al. | 2017-12-28 |
Substituted imidazopyridine and triazolopyridine compounds as negative allosteric modulators of mGluR5 Grant 9,844,542 - Emmitte , et al. December 19, 2 | 2017-12-19 |
Substituted 4-alkoxypicolinamide Analogs As Mglur5 Negative Allosteric Modulators And Methods Of Making And Using The Same App 20170247366 - EMMITTE; Kyle A. ;   et al. | 2017-08-31 |
Substituted 4-benzyl-3,4-dihydro-2H-benzo[B][1,4]oxazine-2-carboxamide analogs as positive allosteric modulators of muscarinic acetycholine receptor M1 Grant 9,708,278 - Lindsley , et al. July 18, 2 | 2017-07-18 |
Substituted pyrazolo[1,5-a]pyrazines as negative allosteric modulators of metabotropic glutamate receptor 3 Grant 9,676,782 - Conn , et al. June 13, 2 | 2017-06-13 |
Substituted 2-(4-heterocyclylbenzyl)isoindolin-1-one Analogs As Positive Allosteric Modulators Of The Muscarinic Acetylcholine Receptor M1 App 20170129889 - Lindsley; Craig W. ;   et al. | 2017-05-11 |
Substituted thieno[2,3-C]pyridazine-6-carboxamide analogs as positive allosteric modulators of the muscarinic acetylcholine receptor M4 Grant 9,637,498 - Lindsley , et al. May 2, 2 | 2017-05-02 |
Substituted 2-(4-heterocyclylbenzyl)isoindolin-1-one analogs as positive allosteric modulators of the muscarinic acetylcholine receptor M1 Grant 9,586,964 - Lindsley , et al. March 7, 2 | 2017-03-07 |
Substituted 5-aminothieno[2,3-c]pyridazine-6-carboxamide Analogs As Positive Allosteric Modulators Of The Muscarinic Acetylcholine Receptor M4 App 20170022216 - Lindsley; Craig W. ;   et al. | 2017-01-26 |
Substituted 4-benzyl-3,4-dihydro-2h-benzo[b][1,4]oxazine-2carboxamide Analogs As Positive Allosteric Modulators Of Muscarinic Acetycholine Receptor M1 App 20170022173 - Lindsley; Craig W. ;   et al. | 2017-01-26 |
Substituted 6-aryl-imidazopyridine and 6-aryl-triazolopyridine carboxamide analogs as negative allosteric modulators of mGluR5 Grant 9,550,778 - Emmitte , et al. January 24, 2 | 2017-01-24 |
Substituted quinazolin-4(3H)-ones, pyrido[3,4-d]pyrimidin-4(3H)-ones, pyrido[3,2-d]pyrimidin-4(3H)-ones and pyrido[2,3-d]pyrimidin-4(3H)-ones as positive allosteric modulators of muscarinic acetycholine receptor M1 Grant 9,540,371 - Lindsley , et al. January 10, 2 | 2017-01-10 |
Substituted bicyclic heteroaryl carboxamide analogs as mGluR5 negative allosteric modulators Grant 9,533,982 - Conn , et al. January 3, 2 | 2017-01-03 |
Substituted 1-benzylquinoxalin-2(1H)-one analogs as positive allosteric modulators of muscarinic acetylcholine receptor M1 Grant 9,527,834 - Lindsley , et al. December 27, 2 | 2016-12-27 |
Substituted 5-aminothieno[2,3--C]pyridazine-6-carboxamide analogs as positive allosteric modulators of the muscarinic acetylcholine receptor M4 Grant 9,493,481 - Lindsley , et al. November 15, 2 | 2016-11-15 |
Substituted Imidazopyridine And Triazolopyridine Compounds As Negative Allosteric Modulators Of Mglur5 App 20160289227 - Emmitte; Kyle A. ;   et al. | 2016-10-06 |
Negative Allosteric Modulators Of Metabotropic Glutamate Receptor 2 App 20160214940 - Conn; P. Jeffrey ;   et al. | 2016-07-28 |
Substituted Thieno[2,3-c]pyridazine-6-carboxamide Analogs As Positive Allosteric Modulators Of The Muscarinic Acetylcholine Receptor M4 App 20160207935 - Lindsley; Craig W. ;   et al. | 2016-07-21 |
Substituted Thieno[2,3-b]pyridine-2-carboxamide Analogs As Positive Allosteric Modulators Of The Muscarinic Acetylcholine Receptor M4 App 20160200733 - LINDSLEY; Craig W. ;   et al. | 2016-07-14 |
Negative allosteric modulators of metabotropic glutamate receptor 2 Grant 9,382,208 - Conn , et al. July 5, 2 | 2016-07-05 |
Substituted 3-benzylquinoxalin-4(3h)-one Analogs As Positive Allosteric Modulators Of Muscarinic Acetycholine Receptor M1 App 20160102090 - Lindsley; Craig W. ;   et al. | 2016-04-14 |
Substituted 6-aryl-imidazopyridine And 6-aryl-triazolopyridine Carboxamide Analogs As Negative Allosteric Modulators Of Mglur5 App 20160096833 - Emmitte; Kyle A. ;   et al. | 2016-04-07 |
Substituted 1-benzylquinoxalin-2(1h) Analogs As Positive Allosteric Modulators Of Muscarinic Acetylcholine Receptor M1 App 20160075690 - Lindsley; Craig W. ;   et al. | 2016-03-17 |
Substituted pyrazolo[1,5-a]pyrazines as mGluR5 receptor modulators Grant 9,255,103 - Conn , et al. February 9, 2 | 2016-02-09 |
Negative Allosteric Modulators Of Metabotropic Glutamate Receptor 3 App 20150361081 - Conn; P. Jeffrey ;   et al. | 2015-12-17 |
Heterocyclic sulfone mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction Grant 9,192,603 - Conn , et al. November 24, 2 | 2015-11-24 |
mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction Grant 9,180,192 - Conn , et al. November 10, 2 | 2015-11-10 |
Pyrazolopyridine, pyrarolopyrazine, pyrazolopyrimidine, pyrazolothiophene and pyrazolothiazole compounds as MGLUR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction Grant 9,163,015 - Conn , et al. October 20, 2 | 2015-10-20 |
Substituted Bicyclic Heteroaryl Carboxamide Analogs As Mglur5 Negative Allosteric Modulators App 20150266866 - Conn; P. Jeffrey ;   et al. | 2015-09-24 |
Pyrazolopyridine, pyrazolopyrazine, pyrazolopyrimidine, pyrazolothiophene and pyrazolothiazole compounds as MGLUR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction Grant 9,108,963 - Conn , et al. August 18, 2 | 2015-08-18 |
Substituted Bicyclic Alkoxy Pyrazole Analogs As Allosteric Modulators Of Mglur5 Receptors App 20150216863 - Conn; P. Jeffrey ;   et al. | 2015-08-06 |
Bicyclic oxazole and thiazole compounds and their use as allosteric modulators of mGluR5 receptors Grant 9,090,632 - Conn , et al. July 28, 2 | 2015-07-28 |
6-alkyl-N-(pyridin-2-yl)-4-aryloxypicolinamide analogs as mGluR5 negative allosteric modulators and methods of making and using the same Grant 9,085,562 - Conn , et al. July 21, 2 | 2015-07-21 |
Substituted benzylspiroindolin-2-one analogs as positive allosteric modulators of the muscarinic acetylcholine receptor M1 Grant 9,073,935 - Lindsley , et al. July 7, 2 | 2015-07-07 |
Substituted pyrazolo[3',4':4,5]thieno[2,3-C]pyridazin-3-amine analogs as positive allosteric modulators of the muscarinic acetylcholine receptor M4 Grant 9,056,875 - Lindsley , et al. June 16, 2 | 2015-06-16 |
Substituted 1-benzylindolin-2-one analogs as positive allosteric modulators of muscarinic acetylcholine M1 receptors Grant 9,029,563 - Lindsley , et al. May 12, 2 | 2015-05-12 |
Substituted bicyclic alkoxy pyrazole analogs as allosteric modulators of mGluR5 receptors Grant 9,029,366 - Conn , et al. May 12, 2 | 2015-05-12 |
Substituted 4-(1H-pyrazol-4-yl)benzyl analogues as positive allosteric modulators of mAChR M.sub.1 receptors Grant 9,012,445 - Lindsley , et al. April 21, 2 | 2015-04-21 |
Substituted 6-methylnicotinamides as mGluR5 positive allosteric modulators Grant 8,969,389 - Conn , et al. March 3, 2 | 2015-03-03 |
Substituted 5-aminothieno[2,3-c]pyridazine-6-carboxamide Analogs As Positive Allosteric Modulators Of The Muscarinic Acetylcholine Receptor M4 App 20150018309 - Lindsley; Craig W ;   et al. | 2015-01-15 |
Benzisoxazoles and azabenzisoxazoles as MGLUR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction Grant 8,916,584 - Conn , et al. December 23, 2 | 2014-12-23 |
Aryl and heteroaryl sulfones as mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction Grant 8,912,336 - Conn , et al. December 16, 2 | 2014-12-16 |
Substituted Pyrazolo[3',4':4,5]thieno[2,3-c]pyridazin-3-amine Analogs As Positive Allosteric Modulators Of The Muscarinic Acetylcholine Receptor M4 App 20140364409 - Lindsley; Craig W. ;   et al. | 2014-12-11 |
Substituted bicyclic alkoxy pyrazole analogs as allosteric modulators of mGluR5 receptors Grant 8,901,125 - Conn , et al. December 2, 2 | 2014-12-02 |
Substituted Imidazopyrimidin-5(6h)-ones As Allosteric Modulators Of Mglur5 Receptors App 20140329838 - Conn; P. Jeffrey ;   et al. | 2014-11-06 |
Substituted imidazopyrimidin-5(6H)-ones as allosteric modulators of MGLUR5 receptors Grant 8,865,725 - Conn , et al. October 21, 2 | 2014-10-21 |
Benzamide mGluR5 positive allosteric modulators and methods of making and using same Grant 8,853,392 - Conn , et al. October 7, 2 | 2014-10-07 |
Naphthyridinone analogs as mGluR5 positive allosteric modulators Grant 8,853,237 - Conn , et al. October 7, 2 | 2014-10-07 |
Substituted 2-(4-heterocyclylbenzyl)isoindolin-1-one Analogs As Positive Allosteric Modulators Of The Muscarinic Acetylcholine Receptor M1 App 20140288084 - Lindsley; Craig W. ;   et al. | 2014-09-25 |
Substituted benzamide analogs as mGluR5 negative allosteric modulators and methods of making and using the same Grant 8,796,295 - Conn , et al. August 5, 2 | 2014-08-05 |
Bicyclic Pyrazole Compounds As Allosteric Modulators Of Mglur5 Receptors App 20140213593 - Conn; P. Jeffrey ;   et al. | 2014-07-31 |
6-alkyl-n-(pyridin-2-yl)-4-aryloxypicolinamide Analogs As Mglur5 Negative Allosteric Modulators And Methods Of Making And Using The Same App 20140206707 - Conn; P. Jeffrey ;   et al. | 2014-07-24 |
Substituted 4-(1h-pyrazol-4-yl)benzyl Analogues As Positive Allosteric Modulators Of Machr M1 Receptors App 20140206676 - Lindsley; Craig W. ;   et al. | 2014-07-24 |
MGLUR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction Grant 8,779,157 - Conn , et al. July 15, 2 | 2014-07-15 |
Substituted 1-benzylindolin-2-one Analogs As Positive Allosteric Modulators Of Muscarinic Acetylcholine M1 Receptors App 20140194471 - Lindlsley; Craig W. ;   et al. | 2014-07-10 |
Indole compounds as positive allosteric modulators of the muscarinic receptor Grant 8,772,509 - Lindsley , et al. July 8, 2 | 2014-07-08 |
Substituted dioxopiperidines and dioxopyrrolidines as MGLUR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction Grant 8,759,377 - Conn , et al. June 24, 2 | 2014-06-24 |
Dihydronaphthyridinyl(organo)methanone analogs as positive allosteric mGluR5 modulators Grant 8,710,074 - Conn , et al. April 29, 2 | 2014-04-29 |
Substituted pyrazolo[1,5-A]pyrazine compounds as allosteric modulators of mGluR5 receptors Grant 8,703,946 - Conn , et al. April 22, 2 | 2014-04-22 |
Substituted (1-(methylsulfonyl)azetidin-3-yl)(heterocycloalkyl)methanone analogs as antagonists of muscarinic acetylcholine M.sub.1 receptors Grant 8,697,888 - Lindsley , et al. April 15, 2 | 2014-04-15 |
Alkyl 3-((2-amidoethyl)amino)-8-azabicyclo[3.2.1]octane-8-carboxylate analogs as selective M1 agonists and methods of making and using same Grant 8,697,691 - Conn , et al. April 15, 2 | 2014-04-15 |
Bicyclic Triazole And Pyrazole Lactams As Allosteric Modulators Of Mglur5 Receptors App 20140057870 - Conn; P. Jeffrey ;   et al. | 2014-02-27 |
Substituted 1,1,3,1-tetraoxidobenzo[D][1,3,2]dithiazoles as MGLUR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction Grant 8,658,650 - Conn , et al. February 25, 2 | 2014-02-25 |
Substituted Bicyclic Aralkyl Pyrazole Lactam Analogs As Allosteric Modulators Of Mglur5 Receptors App 20130345205 - Conn; P. Jeffrey ;   et al. | 2013-12-26 |
Substituted Bicyclic Cycloalkyl Pyrazole Lactam Analogs As Allosteric Modulators Of Mglur5 Receptors App 20130345204 - Conn; P. Jeffrey ;   et al. | 2013-12-26 |
Substituted Bicyclic Alkoxy Pyrazole Analogs As Allosteric Modulators Of Mglur5 Receptors App 20130345206 - Conn; P. Jeffrey ;   et al. | 2013-12-26 |
Substituted Bicyclic Alkoxy Pyrazole Analogs As Allosteric Modulators Of Mglur5 Receptors App 20130345203 - Conn; P. Jeffrey ;   et al. | 2013-12-26 |
Mglur4 Allosteric Potentiators, Compositions, And Methods Of Treating Neurological Dysfunction App 20130338154 - Conn; P. Jeffrey ;   et al. | 2013-12-19 |
Substituted heteroarylamide analogs as mGluR5 negative allosteric modulators and methods of making and using the same Grant 8,598,345 - Conn , et al. December 3, 2 | 2013-12-03 |
Bicyclic triazole and pyrazole lactams as allosteric modulators of mGluR5 receptors Grant 8,592,422 - Conn , et al. November 26, 2 | 2013-11-26 |
Substituted heteroarylamine carboxamide analogs as mGluR5 negative allosteric modulators and methods of making and using the same Grant 8,569,308 - Conn , et al. October 29, 2 | 2013-10-29 |
Bicyclic Oxazole And Thiazole Compounds And Their Use As Allosteric Modulators Of Mglur5 Receptors App 20130261107 - Conn; P. Jeffrey ;   et al. | 2013-10-03 |
Bicyclic Oxazole Lactams As Allosteric Modulators Of Mglur5 Receptors App 20130252943 - Conn; P. Jeffrey ;   et al. | 2013-09-26 |
Substituted Imidazopyrimidin-5(6h)-ones As Allosteric Modulators Of Mglur5 Receptors App 20130245043 - Conn; P. Jeffrey ;   et al. | 2013-09-19 |
Substituted phenylamine carboxamide analogs as mGluR5 negative allosteric modulators and methods of making and using the same Grant 8,501,757 - Conn , et al. August 6, 2 | 2013-08-06 |
Heterocyclyl-azabicyclo[3.2.1]octane Analogs As Selective M1 Agonists And Methods Of Making And Using Same App 20130197027 - Lindsley; Craig ;   et al. | 2013-08-01 |
3.1.0 bicyclic GlyT1 inhibitors and methods of making and using same Grant 8,497,289 - Lindsley , et al. July 30, 2 | 2013-07-30 |
Substituted (1-(methylsulfonyl)azetidin-3-yl)(heterocycloalkyl)methanone Analogs As Antagonists Of Muscarinic Acetylcholine M1 Receptors App 20130178458 - Lindsley; Craig W. ;   et al. | 2013-07-11 |
Heterocyclic Sulfone MGLUR4 Allosteric Potentiators, Compositions, and Methods of Treating Neurological Dysfunction App 20130158078 - Conn; P. Jeffrey ;   et al. | 2013-06-20 |
Substituted Benzylspiroindolin-2-one Analogs As Positive Allosteric Modulators Of The Muscarinic Acetylcholine Receptor M1 App 20130123236 - Lindsley; Craig W. ;   et al. | 2013-05-16 |
Sulfonyl-piperidin-4-yl methylamine amide analogs as GlyT1 inhibitors, methods for making same, and use of same in treating psychiatric disorders Grant 8,436,019 - Lindsley , et al. May 7, 2 | 2013-05-07 |
Alkylsulfonyl-2,3-dihydrospiro[indene-1,4'-piperidine] analogs as GlyT1 inhibitors, methods for making same, and use of same in treating psychiatric disorders Grant 8,431,700 - Lindsley , et al. April 30, 2 | 2013-04-30 |
Pyrazolopyridine, Pyrazolopyrazine, Pyrazolopyrimidine, Pyrazolothiophene and Pyrazolothiazole Compounds as MGLUR4 Allosteric Potentiators, Compositions, and Methods of Treating Neurological Dysfunction App 20130096110 - Conn; P. Jeffrey ;   et al. | 2013-04-18 |
Benzisoxazoles and Azabenzisoxazoles as MGLUR4 Allosteric Potentiators, Compositions, and Methods of Treating Neurological Dysfunction App 20130079366 - Conn; P. Jeffrey ;   et al. | 2013-03-28 |
Pyrazolopyridine, Pyrazolopyrazine, Pyrazolopyrimidine, Pyrazolothiophene and Pyrazolothiazole Compounds as MGLUR4 Allosteric Potentiators, Compositions, and Methods of Treating Neurological Dysfunction App 20130065895 - Conn; P. Jeffrey ;   et al. | 2013-03-14 |
Mglur4 Allosteric Potentiators, Compositions, And Methods Of Treating Neurological Dysfunction App 20130040944 - Conn; P. Jeffrey ;   et al. | 2013-02-14 |
Bicyclic Pyrazole Compounds As Allosteric Modulators Of Mglur5 Receptors App 20120295913 - Conn; P. Jeffrey ;   et al. | 2012-11-22 |
Mglur4 Allosteric Potentiators, Compositions, And Methods Of Treating Neurological Dysfunction App 20120245153 - Conn; P. Jeffrey ;   et al. | 2012-09-27 |
Aryl And Heteroaryl Sulfones As Mglur4 Allosteric Potentiators, Compositions, And Methods Of Treating Neurological Dysfunction App 20120245185 - Conn; P. Jeffrey ;   et al. | 2012-09-27 |
Bicyclic Triazole And Pyrazole Lactams As Allosteric Modulators Of Mglur5 Receptors App 20120225844 - Conn; P. Jeffrey ;   et al. | 2012-09-06 |
Substituted Enzoimidazolesulfonamides And Substituted Indolesulfonamides As Mglur4 Potentiators App 20120184556 - Conn; P. Jeffrey ;   et al. | 2012-07-19 |
Dihydronaphthyridinyl(organo)methanone Analogs As Positive Allosteric Mglur5 Modulators App 20120178776 - Conn; P. Jeffrey ;   et al. | 2012-07-12 |
Naphthyridinone Analogs As Mglur5 Positive Allosteric Modulators App 20120172391 - Conn; P. Jeffrey ;   et al. | 2012-07-05 |
3.3.0 bicyclic GlyT1 inhibitors and methods of making and using same Grant 8,211,933 - Lindsley , et al. July 3, 2 | 2012-07-03 |
Sulfonyl-azetidin-3-yl-methylamine amide analogs as GlyTl inhibitors, methods for making same, and use of same in treating psychiatric disorders Grant 8,207,155 - Lindsley , et al. June 26, 2 | 2012-06-26 |
Bicyclic Mglur5 Positive Allosteric Modulators And Methods Of Making And Using Same App 20120028956 - Conn; P. Jeffrey ;   et al. | 2012-02-02 |
Bicyclic Mglur5 Positive Allosteric Modulators And Methods Of Making And Using Same App 20120028955 - Conn; P. Jeffrey ;   et al. | 2012-02-02 |
Substituted 1,1,3,1-tetraoxidobenzo[d][1,3,2]dithiazoles As Mglur4 Allosteric Potentiators, Compositions, And Methods Of Treating Neurological Dysfunction App 20110319429 - Conn; P. Jeffrey ;   et al. | 2011-12-29 |
Substituted 6-methylnicotinamides As Mglur5 Positive Allosteric Modulators App 20110294858 - Conn; P. Jeffrey ;   et al. | 2011-12-01 |
Bicyclic mGluR5 positive allosteric modulators and methods of making and using same Grant 8,034,806 - Conn , et al. October 11, 2 | 2011-10-11 |
O-benzyl Nicotinamide Analogs As Mglur5 Positive Allosteric Modulators App 20110183980 - Conn; P. Jeffrey ;   et al. | 2011-07-28 |
Alkyl 3-((2-amidoethyl)amino)-8-azabicyclo[3.2.1]octane-8-carboxylate Analogs As Selective M1 Agonists And Methods Of Making And Using Same App 20110172227 - Conn; P. Jeffrey ;   et al. | 2011-07-14 |
Substituted Heteroarylamine Carboxamide Analogs As Mglur5 Negative Allosteric Modulators And Methods Of Making And Using The Same App 20110172247 - Conn; P. Jeffrey ;   et al. | 2011-07-14 |
Substituted Heteroarylamide Analogs As Mglur5 Negative Allosteric Modulators And Methods Of Making And Using The Same App 20110172248 - Conn; P. Jeffrey ;   et al. | 2011-07-14 |
Substituted Phenylamine Carboxamide Analogs As Mglur5 Negative Allosteric Modulators And Methods Of Making And Using The Same App 20110166158 - Conn; P. Jeffrey ;   et al. | 2011-07-07 |
Substituted Benzamide Analogs As Mglur5 Negative Allosteric Modulators And Methods Of Making And Using The Same App 20110152299 - Conn; P. Jeffrey ;   et al. | 2011-06-23 |
Substituted Dioxopiperidines And Dioxopyrrolidines As Mglur4 Allosteric Potentiators, Compositions, And Methods Of Treating Neurological Dysfunction App 20110124663 - Conn; P. Jeffrey ;   et al. | 2011-05-26 |
Sulfonyl-azetidin-3-yl-methylamine Amide Analogs As Glyt1 Inhibitors, Methods For Making Same, And Use Of Same In Treating Psychiatric Disorders App 20100261696 - Lindsley; Craig W. ;   et al. | 2010-10-14 |
3.3.0 BICYCLIC GlyT1 INHIBITORS AND METHODS OF MAKING AND USING SAME App 20100261773 - Lindsley; Craig W. ;   et al. | 2010-10-14 |
Sulfonyl-piperidin-4-yl Methylamine Amide Analogs As Glyt1 Inhibitors, Methods For Making Same, And Use Of Same In Treating Psychiatric Disorders App 20100256186 - Lindsley; Craig W. ;   et al. | 2010-10-07 |
3.1.0 Bicyclic Glyt1 Inhibitors And Methods Of Making And Using Same App 20100256192 - Lindsley; Craig W. ;   et al. | 2010-10-07 |
Alkylsulfonyl-2,3-dihydrospiro[indene-1,4'-piperidine] Analogs As Glyt1 Inhibitors, Methods For Making Same, And Use Of Same In Treating Psychiatric Disorders App 20100249167 - Lindsley; Craig W. ;   et al. | 2010-09-30 |
Treatment of movement disorders with a metabotropic glutamate 4 receptor positive allosteric modulator App 20100144858 - Conn; P. Jeffrey ;   et al. | 2010-06-10 |
Unnatural Dispyrin Analogues, Preparation And Uses Thereof App 20100035929 - Lindsley; Craig W. ;   et al. | 2010-02-11 |
Bicyclic Mglur5 Positive Allosteric Modulators And Methods Of Making And Using Same App 20090270362 - Conn; P. Jeffrey ;   et al. | 2009-10-29 |
Partial mGluR5 antagonists for treatment of anxiety and CNS disorders Grant 7,531,541 - Conn , et al. May 12, 2 | 2009-05-12 |
BENZAMIDE mGluR5 POSITIVE ALLOSTERIC MODULATORS AND METHODS OF MAKING AND USING SAME App 20090042855 - Conn; P. Jeffrey ;   et al. | 2009-02-12 |
Partial mGluR5 antagonists for treatment of anxiety and CNS disorders App 20070208028 - Conn; P. Jeffrey ;   et al. | 2007-09-06 |
Treatment of psychosis with a muscarinic m1 receptor ectopic activator App 20060233843 - Conn; P. Jeffrey ;   et al. | 2006-10-19 |
Treatment of movement disorders with a metabotropic glutamate 4 receptor positive allosteric modulator App 20060166972 - Conn; P. Jeffrey ;   et al. | 2006-07-27 |