Patent | Date |
---|
Novel Biomarkers For Detecting Senescent Cells App 20220228213 - GRILLARI; Johannes ;   et al. | 2022-07-21 |
Treating cognitive decline and other neurodegenerative conditions by selectively removing senescent cells from neurological tissue Grant 11,351,167 - Laberge , et al. June 7, 2 | 2022-06-07 |
Treatment Of Parkinson's Disease And Other Conditions Caused Or Mediated By Senescent Astrocytes Using Small Molecule Senolytic Agents App 20220096466 - Chinta; Shankar J. ;   et al. | 2022-03-31 |
Treating Cardiovascular Disease By Selectively Eliminating Senescent Cells App 20210169875 - Laberge; Remi-Martin ;   et al. | 2021-06-10 |
Treating Liver Disease By Selectively Eliminating Senescent Cells App 20210169876 - Laberge; Remi-Martin ;   et al. | 2021-06-10 |
Treating Cognitive Decline And Other Neurodegenerative Conditions By Selectively Removing Senescent Cells From Neurological Tissue App 20210030752 - Laberge; Remi-Martin ;   et al. | 2021-02-04 |
Biomarker For Senescent Cells App 20200371122 - Wiley; Christopher D. ;   et al. | 2020-11-26 |
Nucleic acid construct with a p16 promoter that causes a prodrug converting enzyme to be expressed specifically in senescent cells Grant 10,655,144 - Demaria , et al. | 2020-05-19 |
Treating Cognitive Decline And Other Neurodegenerative Conditions By Selectively Removing Senescent Cells From Neurological Tiss App 20200030323 - Laberge; Remi-Martin ;   et al. | 2020-01-30 |
Compositions of matter for treatment of ophthalmic conditions by selectively removing senescent cells from the eye Grant 10,478,432 - Laberge , et al. Nov | 2019-11-19 |
Unit dose of an aryl sulfonamide that is effective for treating eye disease and averting potential vision loss Grant 10,478,433 - Laberge , et al. Nov | 2019-11-19 |
Therapy For Removing Senescent Cells And Treating Senescence-associated Disease Using An Mdm2 Inhibitor App 20190343832 - Laberge; Remi-Martin ;   et al. | 2019-11-14 |
Treatment Of Parkinson's Disease And Other Conditions Caused Or Mediated By Senescent Astrocytes Using Small Molecule Senolytic App 20190269675 - Chinta; Shankar J. ;   et al. | 2019-09-05 |
Passive Vaccine For Elimination Of Senescent Cells App 20190201510 - Vasserot; Alain Philippe ;   et al. | 2019-07-04 |
Treating atherosclerosis by removing senescent foam cell macrophages from atherosclerotic plaques Grant 10,328,058 - Baker , et al. | 2019-06-25 |
Use of sulfonamide inhibitors of BCL-2 and BCL-xL to treat ophthalmic disease by selectively removing senescent cells Grant 10,328,073 - Laberge , et al. | 2019-06-25 |
Immunogenic compositions for inducing an immune response for elimination of senescent cells Grant 10,279,018 - Vasserot , et al. | 2019-05-07 |
Treating pulmonary conditions by selectively removing senescent cells from the lung using an intermittent dosing regimen Grant 10,258,618 - Laberge , et al. | 2019-04-16 |
Method of optimizing conditions for selectively removing a plurality of senescent cells from a tissue or a mixed cell population Grant 10,213,426 - Laberge , et al. Feb | 2019-02-26 |
Use Of Sulfonamide Inhibitors Of Bcl-2 And Bcl-xl To Treat Ophthalmic Disease By Selectively Removing Senescent Cells App 20190022090 - Laberge; Remi-Martin ;   et al. | 2019-01-24 |
Pharmaceutical Products and Drug Combinations for Treating Atherosclerosis by Stabilizing Atherosclerotic Plaques and Promoting Plaque Regression App 20190000846 - van Deursen; Jan M.A. ;   et al. | 2019-01-03 |
Treatment of joint pain Grant 10,130,628 - David , et al. November 20, 2 | 2018-11-20 |
Unit Dose of an MDM2 Inhibitor that Provides Long-Lasting Relief from Idiopathic Pulmonary Fibrosis and other Pulmonary Conditions by Selectively Removing Senescent Cells from the Lung App 20180303828 - Laberge; Remi-Martin ;   et al. | 2018-10-25 |
Methods and Compositions for Killing Senescent Cells and for Treating Senescence-Associated Diseases and Disorders App 20180256568 - Laberge; Remi-Martin ;   et al. | 2018-09-13 |
Treatment of Ophthalmic Conditions by Selectively Removing Senescent Cells from the Eye App 20180235957 - Laberge; Remi-Martin ;   et al. | 2018-08-23 |
Treating Pulmonary Conditions By Selectively Removing Senescent Cells From The Lung Using An Intermittent Dosing Regimen App 20180235956 - Laberge; Remi-Martin ;   et al. | 2018-08-23 |
Compositions And Methods For Treating Senescence-associated Diseases And Disorders App 20180193458 - Lopez-Dominguez; Jose Alberto ;   et al. | 2018-07-12 |
Treatment of ophthalmic conditions by selectively removing senescent cells from the eye Grant 10,010,546 - Laberge , et al. July 3, 2 | 2018-07-03 |
Treatment for osteoarthritis in a joint by administering a means for inhibiting MDM2 Grant 9,993,472 - Laberge , et al. June 12, 2 | 2018-06-12 |
Use of sulfonamide inhibitors of Bcl-2 to treat senescence-associated lung conditions such as pulmonary fibrosis and chronic obstructive pulmonary disease Grant 9,980,962 - Laberge , et al. May 29, 2 | 2018-05-29 |
Nucleic Acid Construct with a p16 Promoter that Causes a Prodrug Converting Enzyme to be Expressed Specifically in Senescent Cells App 20180139939 - Demaria; Marco ;   et al. | 2018-05-24 |
Treatment Of Ophthalmic Conditions By Selectively Removing Senescent Cells From The Eye App 20180117038 - Laberge; Remi-Martin ;   et al. | 2018-05-03 |
Transgenic mouse for determining the role of senescent cells in cancer Grant 9,901,081 - Campisi , et al. February 27, 2 | 2018-02-27 |
Transgenic mouse having a transgene that converts a prodrug into a cytotoxic compound in senescent cells Grant 9,901,080 - Campisi , et al. February 27, 2 | 2018-02-27 |
Inhibiting activity of senescent cells using a glucocorticoid Grant 9,884,065 - Campisi , et al. February 6, 2 | 2018-02-06 |
Treatment for osteoarthritis by intra-articular administration of a cis-imidazoline Grant 9,855,266 - Laberge , et al. January 2, 2 | 2018-01-02 |
Unit dose of a cis-imidazoline for treating an osteoarthritic joint by removing senescent cells Grant 9,849,128 - Laberge , et al. December 26, 2 | 2017-12-26 |
Methods And Compositions For Killing Senescent Cells And For Treating Senescence-associated Diseases And Disorders App 20170348307 - Laberge; Remi-Martin ;   et al. | 2017-12-07 |
Treatment of Pain App 20170326136 - David; Nathaniel ;   et al. | 2017-11-16 |
Methods And Compositions For Killing Senescent Cells And For Treating Senescence-associated Diseases And Disorders App 20170224680 - Laberge; Remi-Martin ;   et al. | 2017-08-10 |
Methods And Compositions For Killing Senescent Cells And For Treating Senescence-associated Diseases And Disorders App 20170209435 - Laberge; Remi-Martin ;   et al. | 2017-07-27 |
Methods And Compositions For Killing Senescent Cells And For Treating Senescence-associated Diseases And Disorders App 20170196858 - Laberge; Remi-Martin ;   et al. | 2017-07-13 |
Methods And Compositions For Killing Senescent Cells And For Treating Senescence-associated Diseases And Disorders App 20170196857 - Laberge; Remi-Martin ;   et al. | 2017-07-13 |
Methods And Compositions For Killing Senescent Cells And For Treating Senescence-associated Diseases And Disorders App 20170198253 - Laberge; Remi-Martin ;   et al. | 2017-07-13 |
Methods For Improving Medical Therapies App 20170119789 - Campisi; Judith ;   et al. | 2017-05-04 |
Animal Models For Cancer And Uses Thereof App 20170042129 - Campisi; Judith ;   et al. | 2017-02-16 |
Animal Models Of Age-related Disorders And Age-sensitive Traits Associated With Senescence-inducing Stimuli And Uses Thereof App 20170027139 - van Deursen; Jan M.A. ;   et al. | 2017-02-02 |
Methods And Compositions For Killing Senescent Cells And For Treating Senescence-associated Diseases And Disorders App 20160339019 - Laberge; Remi-Martin ;   et al. | 2016-11-24 |
Immunogenic Compositions For Inducing An Immune Response For Elimination Of Senescent Cells App 20160038576 - Vasserot; Alain Philippe ;   et al. | 2016-02-11 |
Methods For Improving Medical Therapies App 20140335074 - Campisi; Judith ;   et al. | 2014-11-13 |
Id-1 and Id-2 genes and products as therapeutic targets for treatment of breast cancer and other types of carcinoma Grant 8,846,629 - Desprez , et al. September 30, 2 | 2014-09-30 |
Id-1 gene and gene products as therapeutic targets for treatment of breast cancer and other types of carcinoma Grant 8,809,291 - Desprez , et al. August 19, 2 | 2014-08-19 |
Targeting Senescent Cells And Cancer Cells By Interference With Jnk And/or Foxo4 App 20130288981 - de KEIZER; Peterus Leonardus-Josephus ;   et al. | 2013-10-31 |
Targeting Senescent And Cancer Cells For Selective Killing By Interference With Foxo4 App 20130288980 - De Keizer; Peterus Leonardus-Josephus ;   et al. | 2013-10-31 |
Id-1 Gene and Gene Products as Therapeutic Targets for Treatment of Breast Cancer and Other Types of Carcinoma App 20120021047 - Desprez; Pierre-Yves ;   et al. | 2012-01-26 |
Id-1 and Id-2 genes and products as markers of epithelial cancer Grant 8,030,012 - Desprez , et al. October 4, 2 | 2011-10-04 |
Id-1 and Id-2 Genes and Products as Therapeutic Targets for Treatment of Breast Cancer and Other Types of Carcinoma App 20090180988 - Desprez; Pierre-Yves ;   et al. | 2009-07-16 |
Id-1 and Id-2 genes and products as markers of epithelial cancer Grant 7,429,457 - Desprez , et al. September 30, 2 | 2008-09-30 |
Method for sensitive measure of low level apoptosis in cells App 20060263809 - Campisi; Judith ;   et al. | 2006-11-23 |
Id-1 and Id-2 genes and products as markers of epithelial cancer App 20060234273 - Desprez; Pierre-Yves ;   et al. | 2006-10-19 |
Id-1 and Id-2 genes and products as diagnostic and prognostic markers and therapeutic targets for treatment of breast cancer and other types of carcinoma App 20020137064 - Desprez, Pierre-Yves ;   et al. | 2002-09-26 |
Biomarkers of cell senescence Grant 5,795,728 - Dimri , et al. August 18, 1 | 1998-08-18 |