Patent | Date |
---|
Spray-dried Dispersions, Formulations, And Polymorphs Of (s)-5-amino-3-(4-((5-fluoro-2-methoxybenzamido)methyl)phenyl)-1-(1,1,1-tr- Ifluoropropan-2-yl)-1h-pyrazole-4-carboxamide App 20210330643 - Brandhuber; Barbara J. ;   et al. | 2021-10-28 |
Substituted Pyrazolo[1,5-a]pyridine Compounds As Ret Kinase Inhibitors App 20210186959 - Andrews; Steven W. ;   et al. | 2021-06-24 |
Point Mutations In Trk Inhibitor-resistant Cancer And Methods Relating To The Same App 20210164055 - Nanda; Nisha ;   et al. | 2021-06-03 |
Substituted pyrazolo[1,5-a]pyridine compounds as RET kinase inhibitors Grant 10,953,005 - Andrews , et al. March 23, 2 | 2021-03-23 |
Point mutations in TRK inhibitor-resistant cancer and methods relating to the same Grant 10,907,215 - Nanda , et al. February 2, 2 | 2021-02-02 |
Bicyclic urea, thiourea, guanidine and cyanoguanidine compounds useful for the treatment of pain Grant 10,889,589 - Allen , et al. January 12, 2 | 2021-01-12 |
Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors Grant 10,881,652 - Andrews , et al. January 5, 2 | 2021-01-05 |
Substituted Pyrazolo[1,5-a]pyridine Compounds As Ret Kinase Inhibitors App 20200383966 - ANDREWS; Steven W. ;   et al. | 2020-12-10 |
Methods of treatment using pyrrolidinyl urea, thiourea, guanidine and cyanoguanidine compounds Grant 10,851,080 - Allen , et al. December 1, 2 | 2020-12-01 |
Point mutations in TRK inhibitor-resistant cancer and methods relating to the same Grant 10,724,102 - Nanda , et al. | 2020-07-28 |
Point mutations in TRK inhibitor-resistant cancer and methods relating to the same Grant 10,655,186 - Nanda , et al. | 2020-05-19 |
Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors Grant 10,555,944 - Andrews , et al. Feb | 2020-02-11 |
Substituted Pyrazolo[1,5-a]pyridine Compounds As Ret Kinase Inhibitors App 20200030311 - ANDREWS; Steven W. ;   et al. | 2020-01-30 |
Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors Grant 10,441,581 - Andrews , et al. Oc | 2019-10-15 |
Bicyclic Urea, Thiourea, Guanidine And Cyanoguanidine Compounds Useful For The Treatment Of Pain App 20190270749 - Allen; Shelley ;   et al. | 2019-09-05 |
Point mutations in TRK inhibitor-resistant cancer and methods relating to the same Grant 10,378,068 - Nanda , et al. A | 2019-08-13 |
Point mutations in TRK inhibitor-resistant cancer and methods relating to the same Grant 10,370,727 - Nanda , et al. | 2019-08-06 |
Bicyclic urea, thiourea, guanidine and cyanoguanidine compounds useful for the treatment of pain Grant 10,351,575 - Allen , et al. July 16, 2 | 2019-07-16 |
Substituted Pyrazolo[1,5-a]pyridine Compounds As Ret Kinase Inhibitors App 20190183886 - Andrews; Steven W. ;   et al. | 2019-06-20 |
Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors Grant 10,172,845 - Andrews , et al. J | 2019-01-08 |
Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors Grant 10,172,851 - Andrews , et al. J | 2019-01-08 |
Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors Grant 10,144,734 - Andrews , et al. De | 2018-12-04 |
Substituted pyrazolo[1,5-a]pyridine compounds as RET kinase inhibitors Grant 10,137,124 - Andrews , et al. November 27, 2 | 2018-11-27 |
Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors Grant 10,112,942 - Andrews , et al. October 30, 2 | 2018-10-30 |
Methods Of Treatment Using Pyrrolidinyl Urea, Thiourea, Guanidine And Cyanoguanidine Compounds App 20180179182 - Allen; Shelley ;   et al. | 2018-06-28 |
Substituted Pyrazolo[1,5-a]pyridine Compounds As Ret Kinase Inhibitors App 20180148445 - Andrews; Steven W. ;   et al. | 2018-05-31 |
Thiazolyl and oxazolyl urea, thiourea, guanidine and cyanoguanidine compounds as TrkA kinase inhibitors Grant 9,981,959 - Brandhuber , et al. May 29, 2 | 2018-05-29 |
Point Mutations In Trk Inhibitor-resistant Cancer And Methods Relating To The Same App 20180142306 - Nanda; Nisha ;   et al. | 2018-05-24 |
Substituted Pyrazolo[1,5-a]pyridine Compounds As Ret Kinase Inhibitors App 20180134703 - Andrews; Steven W. ;   et al. | 2018-05-17 |
Substituted Pyrazolo[1,5-a]pyridine Compounds As Ret Kinase Inhibitors App 20180134702 - Andrews; Steven W. ;   et al. | 2018-05-17 |
Substituted Pyrazolo[1,5-a]pyridine Compounds As Ret Kinase Inhibitors App 20180133207 - Andrews; Steven W. ;   et al. | 2018-05-17 |
Substituted Pyrazolo[1,5-a]pyridine Compounds As Ret Kinase Inhibitors App 20180133200 - Andrews; Steven W. ;   et al. | 2018-05-17 |
Substituted Pyrazolo[1,5-a]pyridine Compounds As Ret Kinase Inhibitors App 20180133213 - Andrews; Steven W. ;   et al. | 2018-05-17 |
N-(arylalkyl)-N'-pyrazolyl-urea, thiourea, guanidine and cyanoguanidine compounds as TrkA kinase inhibitors Grant 9,969,694 - Blake , et al. May 15, 2 | 2018-05-15 |
Point Mutations In Trk Inhibitor-resistant Cancer And Methods Relating To The Same App 20180119228 - Nanda; Nisha ;   et al. | 2018-05-03 |
N-pyrrolidinyl,N'-pyrazolyl-urea, thiourea, guanidine and cyanoguanidine compounds as TrkA kinase inhibitors Grant 9,896,435 - Allen , et al. February 20, 2 | 2018-02-20 |
Point Mutations In Trk Inhibitor-resistant Cancer And Methods Relating To The Same App 20180030549 - Nanda; Nisha ;   et al. | 2018-02-01 |
Point Mutations In Trk Inhibitor-resistant Cancer And Methods Relating To The Same App 20180030548 - Nanda; Nisha ;   et al. | 2018-02-01 |
Pyrrolidinyl urea, thiourea, guanidine and cyanoguanidine compounds as TrkA kinase inhibitors Grant 9,828,360 - Allen , et al. November 28, 2 | 2017-11-28 |
Bicyclic heteroaryl urea, thiourea, guanidine and cyanoguanidine compounds as TrkA kinase inhibitors Grant 9,822,118 - Allen , et al. November 21, 2 | 2017-11-21 |
Pyrazolyl urea, thiourea, guanidine and cyanoguanidine compounds as trkA kinase inhibitors Grant 9,809,578 - Brandhuber , et al. November 7, 2 | 2017-11-07 |
N-(monocyclic aryl),N'-pyrazolyl-urea, thiourea, guanidine and cyanoguanidine compounds as TrkA kinase inhibitors Grant 9,790,210 - Andrews , et al. October 17, 2 | 2017-10-17 |
Pyrrolidinyl urea, thiourea, guanidine and cyanoguanidine compounds as TrkA kinase inhibitors Grant 9,790,178 - Allen , et al. October 17, 2 | 2017-10-17 |
Point Mutations In Trk Inhibitor-resistant Cancer And Methods Relating To The Same App 20170260589 - Nanda; Nisha ;   et al. | 2017-09-14 |
N-bicyclic aryl,N'-pyrazolyl urea, thiourea, guanidine cyanoguanidine compounds as TrkA kinase inhibitors Grant 9,546,156 - Allen , et al. January 17, 2 | 2017-01-17 |
Bicyclic Urea, Thiourea, Guanidine And Cyanoguanidine Compounds Useful For The Treatment Of Pain App 20160355521 - Allen; Shelley ;   et al. | 2016-12-08 |
Bicyclic Heteroaryl Urea, Thiourea, Guanidine And Cyanoguanidine Compounds As Trka Kinase Inhibitors App 20160355517 - Allen; Shelley ;   et al. | 2016-12-08 |
Pyrrolidinyl Urea, Thiourea, Guanidine And Cyanoguanidine Compounds As Trka Kinase Inhibitors App 20160297796 - Allen; Shelley ;   et al. | 2016-10-13 |
Pyrrolidinyl Urea, Thiourea, Guanidine And Cyanoguanidine Compounds As Trka Kinase Inhibitors App 20160297758 - Allen; Shelley ;   et al. | 2016-10-13 |
N-(monocyclic Aryl),n'-pyrazolyl-urea, Thiourea, Guanidine And Cyanoguanidine Compounds As Trka Kinase Inhibitors App 20160280692 - Andrews; Steven Wade ;   et al. | 2016-09-29 |
N-pyrrolidinyl,n'-pyrazolyl-urea, Thiourea, Guanidine And Cyanoguanidine Compounds As Trka Kinase Inhibitors App 20160280682 - Allen; Shelley ;   et al. | 2016-09-29 |
Thiazolyl And Oxazolyl Urea, Thiourea, Guanidine And Cyanoguanidine Compounds As Trka Kinase Inhibitors App 20160280702 - Brandhuber; Barbara J. ;   et al. | 2016-09-29 |
Pyrazolyl Urea, Thiourea, Guanidine And Cyanoguanidine Compounds As Trka Kinase Inhibitors App 20160280690 - Brandhuber; Barbara J. ;   et al. | 2016-09-29 |
N-bicyclic Aryl,n'-pyrazolyl Urea, Thiourea, Guanidine And Cyanoguanidine Compounds As Trka Kinase Inhibitors App 20160280681 - Allen; Shelley ;   et al. | 2016-09-29 |
N-(arylalkyl)-n'-pyrazolyl-urea, Thiourea, Guanidine And Cyanoguanidine Compounds As Trka Kinase Inhibitors App 20160272592 - Blake; James F. ;   et al. | 2016-09-22 |
Method of structure-based drug design to create or improve modulators of IL-1 activity which bind to the interleukin-1 type 1 receptor Grant 7,144,988 - Brandhuber , et al. December 5, 2 | 2006-12-05 |
Method of structure-based drug design to create or improve modular of IL-1 activity which mind to the interleukin-1 type 1 receptor App 20040014643 - Brandhuber, Barbara J. ;   et al. | 2004-01-22 |