Bradner; James E.
Patent Applications and Registrations
Patent applications and USPTO patent grants for Bradner; James E..The latest application filed is for "bivalent bromodomain inhibitors and uses thereof".
Company Profile
27.38.58
- Bradner; James E. - Weston MA
- BRADNER; James E. - Cambridge MA US
Patent Activity
| Patent | Date |
|---|---|
| Combination therapy for cancer using bromodomain and extra-terminal (BET) protein inhibitors Grant 11,446,309 - Bradner , et al. September 20, 2 | 2022-09-20 |
| Acetamide thienotriazolodiazepines and uses thereof Grant 11,406,645 - Bradner , et al. August 9, 2 | 2022-08-09 |
| Bivalent Bromodomain Inhibitors And Uses Thereof App 20220119416 - Bradner; James E. ; et al. | 2022-04-21 |
| Cyano thienotriazolodiazepines and uses thereof Grant 11,306,105 - Bradner , et al. April 19, 2 | 2022-04-19 |
| EZH2 inhibitors and uses thereof Grant 11,236,082 - Bradner , et al. February 1, 2 | 2022-02-01 |
| Acetamide Thienotriazolodiazepines And Uses Thereof App 20210393647 - Bradner; James E. ; et al. | 2021-12-23 |
| Bivalent Bromodomain Inhibitors And Uses Thereof App 20210221826 - Bradner; James E. ; et al. | 2021-07-22 |
| Cyano Thienotriazolodiazepines And Uses Thereof App 20210206779 - Bradner; James E. ; et al. | 2021-07-08 |
| Combination Therapy For Cancer Using Bromodomain And Extra-terminal (bet) Protein Inhibitors App 20210100813 - Bradner; James E. ; et al. | 2021-04-08 |
| Acetamide Thienotriazolodiazepines And Uses Thereof App 20210093644 - Bradner; James E. ; et al. | 2021-04-01 |
| Bivalent bromodomain inhibitors and uses thereof Grant 10,913,752 - Bradner , et al. February 9, 2 | 2021-02-09 |
| Acetamide thienotriazolodiazepines and uses thereof Grant 10,881,668 - Bradner , et al. January 5, 2 | 2021-01-05 |
| Mechanism Of Resistance To Bet Bromodomain Inhibitors App 20200368248 - Polyak; Kornelia ; et al. | 2020-11-26 |
| Stabilized Peptide-mediated Targeted Protein Degradation App 20200354413 - Walensky; Loren D. ; et al. | 2020-11-12 |
| Compositions And Methods For Selective Protein Degradation App 20200339704 - Bradner; James E. ; et al. | 2020-10-29 |
| Uses of diazepane derivatives Grant 10,793,571 - Bradner , et al. October 6, 2 | 2020-10-06 |
| Diaminopyrimidine benzenesulfone derivatives and uses thereof Grant 10,730,860 - Bradner , et al. | 2020-08-04 |
| Cyano Thienotriazolodiazepines And Uses Thereof App 20200199150 - Bradner; James E. ; et al. | 2020-06-25 |
| Method for preparing largazole analogs and uses thereof Grant 10,676,504 - Williams , et al. | 2020-06-09 |
| Bivalent Bromodomain Inhibitors And Uses Thereof App 20200172553 - Bradner; James E. ; et al. | 2020-06-04 |
| EZH2 inhibitors and uses thereof Grant 10,633,371 - Bradner , et al. | 2020-04-28 |
| Ezh2 Inhibitors And Uses Thereof App 20200039968 - Bradner; James E. ; et al. | 2020-02-06 |
| Reverse Amide Compounds As Protein Deacetylase Inhibitors And Methods Of Use Thereof App 20200030325 - van Duzer; John H. ; et al. | 2020-01-30 |
| Synthesis and utility of new capgroup largazole analogs Grant 10,538,534 - Williams , et al. Ja | 2020-01-21 |
| Combination Therapy Of Bromodomain Inhibitors And Checkpoint Blockade App 20190192532 - Bradner; James E. ; et al. | 2019-06-27 |
| Diazepane derivatives and uses thereof Grant 10,308,653 - Bradner , et al. | 2019-06-04 |
| Ezh2 Inhibitors And Uses Thereof App 20190135796 - Bradner; James E. ; et al. | 2019-05-09 |
| Diaminopyrimidine Benzenesulfone Derivatives And Uses Thereof App 20190135790 - Bradner; James E. ; et al. | 2019-05-09 |
| Acetamide Thienotriazolodiazepines And Uses Thereof App 20190046541 - Bradner; James E. ; et al. | 2019-02-14 |
| Treatment of protein degradation disorders Grant 10,172,905 - Anderson , et al. J | 2019-01-08 |
| Use Of Compositions Modulating Chromatin Structure For Graft Versus Host Disease (gvhd) App 20190000860 - Bradner; James E. ; et al. | 2019-01-03 |
| Bivalent Bromodomain Inhibitors And Uses Thereof App 20180354973 - Bradner; James E. ; et al. | 2018-12-13 |
| Diaminopyrimidine benzenesulfone derivatives and uses thereof Grant 10,150,756 - Bradner , et al. Dec | 2018-12-11 |
| Ezh2 Inhibitors And Uses Thereof App 20180297993 - Bradner; James E. ; et al. | 2018-10-18 |
| Selective histone deacetylase 8 inhibitors Grant 10,087,149 - Beeler , et al. October 2, 2 | 2018-10-02 |
| Class-and isoform-specific HDAC inhibitors and uses thereof Grant 10,059,657 - Mazitschek , et al. August 28, 2 | 2018-08-28 |
| Inhibitors of transcription factors and uses thereof Grant 9,975,896 - Marineau , et al. May 22, 2 | 2018-05-22 |
| Dihydropteridinone derivatives and uses thereof Grant 9,951,074 - Bradner , et al. April 24, 2 | 2018-04-24 |
| Synthesis and Utility of New Capgroup Largazole Analogs App 20180057510 - Williams; Robert M. ; et al. | 2018-03-01 |
| Method for Preparing Largazole Analogs and Uses Thereof App 20180044376 - Williams; Robert M. ; et al. | 2018-02-15 |
| Plasmids Comprising Internal Ribosomal Entry Sites And Uses Thereof App 20170292959 - Kaelin; William G. ; et al. | 2017-10-12 |
| Class-and Isoform-specific Hdac Inhibitors And Uses Thereof App 20170267630 - Mazitschek; Ralph ; et al. | 2017-09-21 |
| Diagnostic and treatment methods in subjects having or at risk of developing resistance to cancer therapy Grant 9,763,956 - Bernstein , et al. September 19, 2 | 2017-09-19 |
| Bromodomain binding reagents and uses thereof Grant 9,714,946 - Bradner , et al. July 25, 2 | 2017-07-25 |
| Diazepane derivatives and uses thereof Grant 9,695,172 - Bradner , et al. July 4, 2 | 2017-07-04 |
| Diazepane Derivatives And Uses Thereof App 20170145023 - Bradner; James E. ; et al. | 2017-05-25 |
| Dihydropteridinone Derivatives And Uses Thereof App 20170145013 - Bradner; James E. ; et al. | 2017-05-25 |
| Treatment of protein degradation disorders Grant 9,572,854 - Anderson , et al. February 21, 2 | 2017-02-21 |
| Pyrrol-1-yl benzoic acid derivatives useful as myc inhibitors Grant 9,567,301 - Bradner , et al. February 14, 2 | 2017-02-14 |
| Uses Of Diazepane Derivatives App 20170008895 - Bradner; James E. ; et al. | 2017-01-12 |
| Class- and isoform-specific HDAC inhibitors and uses thereof Grant 9,540,317 - Mazitschek , et al. January 10, 2 | 2017-01-10 |
| DOT1L probes Grant 9,535,067 - Bradner , et al. January 3, 2 | 2017-01-03 |
| Reverse Amide Compounds As Protein Deacetylase Inhibitors And Methods Of Use Thereof App 20160375021 - van Duzer; John H. ; et al. | 2016-12-29 |
| Dihydropteridinone Derivatives And Uses Thereof App 20160347750 - Bradner; James E. ; et al. | 2016-12-01 |
| Diazepane Derivatives And Uses Thereof App 20160347749 - Bradner; James E. ; et al. | 2016-12-01 |
| Diaminopyrimidine Benzenesulfone Derivatives And Uses Thereof App 20160332993 - BRADNER; James E. ; et al. | 2016-11-17 |
| DOT1L inhibitors Grant 9,458,165 - Bradner , et al. October 4, 2 | 2016-10-04 |
| Combination Therapy For Cancer Using Bromodomain And Extra-terminal (bet) Protein Inhibitors App 20160279141 - Bradner; James E. ; et al. | 2016-09-29 |
| Deacetylase inhibitors and uses thereof Grant 9,434,686 - Tang , et al. September 6, 2 | 2016-09-06 |
| Inhibitors Of Transcription Factors And Uses Thereof App 20160168154 - Marineau; Jason J. ; et al. | 2016-06-16 |
| Dot1l Probes App 20160146817 - Bradner; James E. ; et al. | 2016-05-26 |
| Bet Inhibition Therapy For Heart Disease App 20160095867 - Haldar; Saptarsi M. ; et al. | 2016-04-07 |
| DOT1L Inhibitors App 20160060269 - Bradner; James E. ; et al. | 2016-03-03 |
| Treatment Of Protein Degradation Disorders App 20160051619 - Anderson; Kenneth C. ; et al. | 2016-02-25 |
| Bromodomain Binding Reagents And Uses Thereof App 20160033519 - Bradner; James E. ; et al. | 2016-02-04 |
| Selective Histone Deacetylase 8 Inhibitors App 20150352079 - BEELER; Aaron Beaty ; et al. | 2015-12-10 |
| Method for preparing largazole analogs and uses thereof Grant 9,186,402 - Williams , et al. November 17, 2 | 2015-11-17 |
| Class- And Isoform-specific Hdac Inhibitors And Uses Thereof App 20150307444 - Mazitschek; Ralph ; et al. | 2015-10-29 |
| Pyrrol-1-yl Benzoic Acid Derivatives Useful As Myc Inhibitors App 20150291521 - Bradner; James E. ; et al. | 2015-10-15 |
| Selective Inhibitors Of Histone Deacetylase Isoform 6 And Methods Thereof App 20150197497 - Abeywickrama; Chandima ; et al. | 2015-07-16 |
| Diagnostic And Treatment Methods In Subjects Having Or At Risk Of Developing Resistance To Cancer Therapy App 20150174138 - Bernstein; Bradley E. ; et al. | 2015-06-25 |
| Genome-wide Method of Assessing Interactions Between Chemical Entities And Their Target Molecules App 20150167062 - Young; Richard A. ; et al. | 2015-06-18 |
| Treatment of protein degradation disorders Grant 8,999,289 - Anderson , et al. April 7, 2 | 2015-04-07 |
| Reverse Amide Compounds As Protein Deacetylase Inhibitors And Methods Of Use Thereof App 20150045380 - van Duzer; John H. ; et al. | 2015-02-12 |
| Reverse Amide Compounds As Protein Deacetylase Inhibitors And Methods Of Use Thereof App 20140142117 - van Duzer; John H. ; et al. | 2014-05-22 |
| Histone Deacetylase Inhibitors And Methods Of Use Thereof App 20140107166 - Mazitschek; Ralph ; et al. | 2014-04-17 |
| Method for Preparing Largazole Analogs and Uses Thereof App 20140093449 - Williams; Robert M. ; et al. | 2014-04-03 |
| Reverse amide compounds as protein deacetylase inhibitors and methods of use thereof Grant 8,609,678 - Van Duzer , et al. December 17, 2 | 2013-12-17 |
| Method for preparing largazole analogs and uses thereof Grant 8,513,290 - Williams , et al. August 20, 2 | 2013-08-20 |
| Reverse amide compounds as protein deacetylase inhibitors and methods of use thereof Grant 8,394,810 - van Duzer , et al. March 12, 2 | 2013-03-12 |
| Method for Preparing Largazole Analogs and Uses Thereof App 20120264794 - Williams; Robert M. ; et al. | 2012-10-18 |
| Reverse Amide Compounds As Protein Deacetylase Inhibitors And Methods Of Use Thereof App 20120190693 - van Duzer; John H. ; et al. | 2012-07-26 |
| Method for preparing largazole analogs and uses thereof Grant 8,217,076 - Williams , et al. July 10, 2 | 2012-07-10 |
| Reverse Amide Compounds As Protein Deacetylase Inhibitors And Methods Of Use Thereof App 20120083504 - van Duzer; John H. ; et al. | 2012-04-05 |
| Reverse amide compounds as protein deacetylase inhibitors and methods of use thereof Grant 8,148,526 - van Duzer , et al. April 3, 2 | 2012-04-03 |
| Reverse Amide Compounds As Protein Deacetylase Inhibitors And Methods Of Use Thereof App 20110300134 - van Duzer; John H. ; et al. | 2011-12-08 |
| Method for preparing largazole analogs and uses thereof App 20100029731 - Williams; Robert M. ; et al. | 2010-02-04 |
| Small Molecule Printing App 20090221433 - Barnes; David W. ; et al. | 2009-09-03 |
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