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Compounds For The Modulation Of Proprotein Convertase Subtilisin/kexin Type 9 (pcsk9) App 20220267269 - Bowers; Simeon ;   et al. | 2022-08-25 |
Compounds For The Modulation Of Proprotein Convertase Subtilisin/kexin Type 9 (pcsk9) App 20220193058 - Bowers; Simeon ;   et al. | 2022-06-23 |
Inhibitors Of Jun N-terminal Kinase App 20220081427 - SHAM; Hing L. ;   et al. | 2022-03-17 |
Composition And Methods Of Use Of Tetrahydroisoquinoline Small Molecules To Bind And Modulate Pcsk9 Protein Activity App 20210309613 - Barta; Thomas E. ;   et al. | 2021-10-07 |
Composition And Methods Of Use Of Novel Phenylalanine Small Organic Compounds To Directly Modulate Pcsk9 Protein Activity App 20210236481 - Barta; Thomas E. ;   et al. | 2021-08-05 |
Tripeptide epoxy ketone protease inhibitors Grant 11,078,233 - McMinn , et al. August 3, 2 | 2021-08-03 |
Phenylpiperazine proprotein convertase subtilisin/kexin type 9 (PCSK9) modulators and their use Grant 10,980,801 - Barta , et al. April 20, 2 | 2021-04-20 |
Compounds For Binding Proprotein Convertase Subtilisin/kexin Type 9 App 20210032214 - Pandey; Anjali ;   et al. | 2021-02-04 |
Composition and methods of use of tetrahydroisoquinoline small molecules to bind and modulate PCSK9 protein activity Grant 10,865,185 - Barta , et al. December 15, 2 | 2020-12-15 |
Composition and methods of use of novel phenylalanine small organic compounds to directly modulate PCSK9 protein activity Grant 10,821,106 - Barta , et al. November 3, 2 | 2020-11-03 |
Inhibitors Of Jun N-terminal Kinase App 20200277285 - SHAM; Hing L. ;   et al. | 2020-09-03 |
Phenylpiperazine Proprotein Convertase Subtilisin/kexin Type 9 (pcsk9) Modulators And Their Use App 20200253958 - Kind Code | 2020-08-13 |
Tripeptide Epoxy Ketone Protease Inhibitors App 20200207809 - McMinn; Dustin ;   et al. | 2020-07-02 |
Tripeptide epoxy ketone protease inhibitors Grant 10,647,744 - McMinn , et al. | 2020-05-12 |
Phenylpiperazine proprotein convertase subtilisin/kexin type 9 (PCSK9) modulators and their use Grant 10,568,882 - Barta , et al. Feb | 2020-02-25 |
Inhibitors Of Jun N-terminal Kinase App 20200039972 - SHAM; Hing L. ;   et al. | 2020-02-06 |
Novel Antibody-drug Conjugates And Related Compounds, Compositions And Methods Of Use App 20190209704 - JACKSON; David Y. ;   et al. | 2019-07-11 |
Inhibitors Of Jun N-terminal Kinase App 20190194176 - SHAM; Hing L. ;   et al. | 2019-06-27 |
Compounds For Binding Proprotein Convertase Subtilisin/kexin Type 9 (pcsk9) App 20190119236 - Pandey; Anjali ;   et al. | 2019-04-25 |
Peptide epoxyketone immunoproteasome inhibitors Grant RE47,302 - McMinn , et al. | 2019-03-19 |
Inhibitors Of Jun N-terminal Kinase App 20180319780 - SHAM; Hing L. ;   et al. | 2018-11-08 |
Composition And Methods Of Use Of Novel Phenylalanine Small Organic Compounds To Directly Modulate Pcsk9 Protein Activity App 20180250291 - Barta; Thomas E. ;   et al. | 2018-09-06 |
Composition And Methods Of Use Of Novel Phenylalanine Small Organic Compounds To Directly Modulate Pcsk9 Protein Activity App 20180237381 - Barta; Thomas E. ;   et al. | 2018-08-23 |
Inhibitors Of Jun N-terminal Kinase App 20180037577 - SHAM; Hing L. ;   et al. | 2018-02-08 |
Substituted cinnolines as inhibitors of LRRK2 kinase activity Grant 9,884,828 - Aubele , et al. February 6, 2 | 2018-02-06 |
Inhibitors of Jun N-terminal kinase Grant 9,796,706 - Sham , et al. October 24, 2 | 2017-10-24 |
Inhibitors Of Jun N-terminal Kinase App 20170107209 - SHAM; Hing L. ;   et al. | 2017-04-20 |
Tripeptide Epoxy Ketone Protease Inhibitors App 20160368946 - McMinn; Dustin ;   et al. | 2016-12-22 |
Spirocyclic dihydro-thiazine and dihydro-oxazine BACE inhibitors, and compositions and uses thereof Grant 9,493,485 - Xu , et al. November 15, 2 | 2016-11-15 |
Spirocyclic Dihydro-thiazine And Dihydro-oxazine Bace Inhibitors, And Compositions And Uses Thereof App 20160272654 - XU; Ying-Zi ;   et al. | 2016-09-22 |
Tripeptide epoxy ketone protease inhibitors Grant 9,434,761 - McMinn , et al. September 6, 2 | 2016-09-06 |
Spirocyclic Dihydro-thiazine And Dihydro-oxazine Bace Inhibitors, And Compositions And Uses Thereof App 20150307518 - Xu; Ying-Zi ;   et al. | 2015-10-29 |
Inhibitors Of Lrrk2 Kinase Activity App 20150284337 - Aubele; Danielle L. ;   et al. | 2015-10-08 |
Inhibitors Of Jun N-terminal Kinase App 20150259330 - SHAM; Hing L. ;   et al. | 2015-09-17 |
Inhibitors of Jun N-terminal kinase Grant 9,073,891 - Sham , et al. July 7, 2 | 2015-07-07 |
Inhibitors Of Polo-like Kinase App 20150126502 - GALEMMO; Robert A. ;   et al. | 2015-05-07 |
Spirocyclic Digydro-thiazine And Dihydro-oxazine Bace Inhibitors, And Compositions And Uses Thereof App 20150087825 - Xu; Ying-Zi ;   et al. | 2015-03-26 |
Spirocyclic Digydro-thiazine And Dihydro-oxazine Bace Inhibitors, And Compositions And Uses Thereof App 20150087826 - Xu; Ying-Zi ;   et al. | 2015-03-26 |
Tripeptide Epoxy Ketone Protease Inhibitors App 20140336106 - McMinn; Dustin ;   et al. | 2014-11-13 |
Inhibitors Of Polo-like Kinase App 20130331376 - Galemmo; Robert A. ;   et al. | 2013-12-12 |
Inhibitors of polo-like kinase Grant 8,541,418 - Galemmo , et al. September 24, 2 | 2013-09-24 |
Inhibitors Of Polo-like Kinase App 20130231335 - Galemmo; Robert A. ;   et al. | 2013-09-05 |
Inhibitors of Jun N-terminal kinase Grant 8,450,363 - Sham , et al. May 28, 2 | 2013-05-28 |
Inhibitors of polo-like kinase Grant 8,445,503 - Galemmo , et al. May 21, 2 | 2013-05-21 |
Inhibitors Of Jun N-terminal Kinase App 20130072494 - SHAM; Hing L. ;   et al. | 2013-03-21 |
N-sulfonamido polycyclic pyrazolyl compounds Grant 8,283,358 - Konradi , et al. October 9, 2 | 2012-10-09 |
Inhibitors of Polo-Like Kinase App 20120115848 - Galemmo, JR.; Robert A. ;   et al. | 2012-05-10 |
Inhibitors Of Polo-like Kinase App 20110212942 - Galemmo; Robert A. ;   et al. | 2011-09-01 |
Inhibitors Of Polo-like Kinase App 20110207716 - Galemmo; Robert A. ;   et al. | 2011-08-25 |
Pyrazolopyrrolidines as inhibitors of gamma secretase Grant 7,977,368 - Dressen , et al. July 12, 2 | 2011-07-12 |
Bridged N-Cyclic Sulfonamido Inhibitors of Gamma Secretase App 20110003802 - Bowers; Simeon ;   et al. | 2011-01-06 |
Inhibitors of Jun N-Terminal Kinase App 20100331335 - Sham; Hing L. ;   et al. | 2010-12-30 |
Substituted hydroxyethylamine aspartyl protease inhibitors Grant 7,858,642 - John , et al. December 28, 2 | 2010-12-28 |
Bridged N-cyclic sulfonamido inhibitors of gamma secretase Grant 7,754,712 - Bowers , et al. July 13, 2 | 2010-07-13 |
N-sulfonamido Polycyclic Pyrazolyl Compounds App 20100081680 - Konradi; Andrei W. ;   et al. | 2010-04-01 |
Substituted Hydroxyethylamine Aspartyl Protease Inhibitors App 20090270367 - JOHN; Varghese ;   et al. | 2009-10-29 |
Pyrazolopyrrolidines as Inhibitors of Gamma Secretase App 20090099235 - Dressen; Darren ;   et al. | 2009-04-16 |
Bridged N-Cyclic Sulfonamido Inhibitors of Gamma Secretase App 20080090817 - Bowers; Simeon ;   et al. | 2008-04-17 |
Bridged N-cyclic sulfonamido inhibitors of gamma secretase Grant 7,345,056 - Bowers , et al. March 18, 2 | 2008-03-18 |
Methods of treating amyloidosis using aryl-cyclopropyl derivative aspartyl protease inhibitors App 20070149525 - Hom; Roy ;   et al. | 2007-06-28 |
Bridged N-Cyclic Sulfonamido Inhibitors of Gamma Secretase App 20070049612 - Bowers; Simeon ;   et al. | 2007-03-01 |
Methods of treatment of amyloidosis using bi-cyclic aspartyl protease inhibitors App 20050239832 - John, Varghese ;   et al. | 2005-10-27 |
Substituted hydroxyethylamine aspartyl protease inhibitors App 20050239836 - John, Varghese ;   et al. | 2005-10-27 |