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Substituted dihydroimidazopyridinediones as MKNK1 and MKNK2 inhibitors Grant 11,311,520 - Klar , et al. April 26, 2 | 2022-04-26 |
Substituted Dihydroimidazopyridinediones As Mknk1 And Mknk2 Inhibitors App 20210085656 - KLAR; Ulrich ;   et al. | 2021-03-25 |
Substituted Dihydroimidazopyridinediones As Mknk1 And Mknk2 Inhibitors App 20190350910 - KLAR; Ulrich ;   et al. | 2019-11-21 |
4-aryl-N-phenyl-1,3,5-triazin-2-amines containing a sulfoximine group Grant 9,962,389 - Lucking , et al. May 8, 2 | 2018-05-08 |
5-fluoro-N-(pyridin-2-yl)pyridin-2-amine derivatives containing a sulfoximine group Grant 9,877,954 - Lucking , et al. January 30, 2 | 2018-01-30 |
Disubstituted 5-fluoro pyrimidine derivatives containing a sulfondiimine group Grant 9,790,189 - Lucking , et al. October 17, 2 | 2017-10-17 |
4-aryl-n-phenyl-1,3,5-triazin-2-amines Containing A Sulfoximine Group App 20170217949 - LUCKING; Ulrich ;   et al. | 2017-08-03 |
5-fluoro-n-(pyridin-2-yl)pyridin-2-amine Derivatives Containing A Sulfoximine Group App 20170202815 - LUCKING; Ulrich ;   et al. | 2017-07-20 |
N-(pyridin-2-yl)pyrimidin-4-amine derivatives containing a sulfone group Grant 9,708,293 - Lucking , et al. July 18, 2 | 2017-07-18 |
5-fluoro-N-(pyridin-2-yl)pyridin-2-amine derivatives containing a sulfone group Grant 9,670,161 - Lucking , et al. June 6, 2 | 2017-06-06 |
4-aryl-N-phenyl-1,3,5-triazin-2-amines containing a sulfoximine group Grant 9,669,034 - Lucking , et al. June 6, 2 | 2017-06-06 |
5-fluoro-N-(pyridin-2-yl)pyridin-2-amine derivatives containing a sulfoximine group Grant 9,650,340 - Lucking , et al. May 16, 2 | 2017-05-16 |
N-(pyridin-2-yl)pyrimidin-4-amine derivatives containing a sulfoximine group Grant 9,650,361 - Lucking , et al. May 16, 2 | 2017-05-16 |
Disubstituted 5-fluoro Pyrimidine Derivatives Containing A Sulfondiimine Group App 20170015634 - LUCKING; Ulrich ;   et al. | 2017-01-19 |
4-(ortho)-fluorophenyl-5-fluoropyrimidin-2-yl amines containing a sulfoximine group Grant 9,499,492 - Lucking , et al. November 22, 2 | 2016-11-22 |
Imidazopyrazines Grant 9,468,642 - Klar , et al. October 18, 2 | 2016-10-18 |
Substituted imidazo[1,2-a]pyrazines as MPS-1 inhibitors Grant 9,284,317 - Koppitz , et al. March 15, 2 | 2016-03-15 |
Substituted imidazopyridazines Grant 9,255,100 - Klar , et al. February 9, 2 | 2016-02-09 |
6-thio-substituted imidazo[1,2-a]pyrazines as Mps-1 inhibitors Grant 9,212,184 - Koppitz , et al. December 15, 2 | 2015-12-15 |
Substituted imidazopyrazines Grant 9,199,999 - Klar , et al. December 1, 2 | 2015-12-01 |
4-(ortho)-fluorophenyl-5-fluoropyrimidin-2-yl Amines Containing A Sulfoximine Group App 20150291537 - Lucking; Ulrich ;   et al. | 2015-10-15 |
5-fluoro-n-(pyridin-2-yl)pyridin-2-amine Derivatives Containing A Sulfoximine Group App 20150291528 - Lucking; Ulrich ;   et al. | 2015-10-15 |
N-(pyridin-2-yl)pyrimidin-4-amine Derivatives Containing A Sulfoximine Group App 20150291559 - Lucking; Ulrich ;   et al. | 2015-10-15 |
5-fluoro-n-(pyridin-2-yl)pyridin-2-amine Derivatives Containing A Sulfone Group App 20150274666 - Lucking; Ulrich ;   et al. | 2015-10-01 |
N-(pyridin-2-yl)pyrimidin-4-amine Derivatives Containing A Sulfone Group App 20150274695 - Lucking; Ulrich ;   et al. | 2015-10-01 |
4-(ortho)-fluorophenyl-5-fluoropyrimidin-2-yl Amines Containing A Sulfone Group App 20150259300 - Lucking; Ulrich ;   et al. | 2015-09-17 |
Disubstituted 5-fluoro pyrimidine derivatives containing a sulfoximine group Grant 9,133,171 - Lucking , et al. September 15, 2 | 2015-09-15 |
Disubstituted 5-fluoro-pyrimidines Grant 9,108,926 - Lucking , et al. August 18, 2 | 2015-08-18 |
17-(1'propenyl)-17-3'-oxidoestra-4-en-3-one derivative, use thereof, and medicament containing said derivative Grant 9,034,856 - Klar , et al. May 19, 2 | 2015-05-19 |
19-nor-steroid derivatives with a 15.alpha.,16.alpha.-methylene group and a saturated 17,17-spirolactone ring, use thereof, and medicaments containing said derivatives Grant 8,987,239 - Klar , et al. March 24, 2 | 2015-03-24 |
6,7-Dihydro-5H-benzo[7]annulene derivatives, processes for their preparation, pharmaceutical products comprising them and their use for preparing medicaments App 20150080438 - Wintermantel; Tim ;   et al. | 2015-03-19 |
17-hydroxy-19-nor-21-carboxylic acid-steroid .gamma.-lactone derivative, use thereof, and medicament containing the derivative Grant 8,937,058 - Klar , et al. January 20, 2 | 2015-01-20 |
Disubstituted 5-fluoro Pyrimidine Derivatives Containing A Sulfoximine Group App 20150005329 - Lucking; Ulrich ;   et al. | 2015-01-01 |
Substituted 4-Aryl-N-phenyl-1,3,5-triazin-2-amines Grant 8,916,557 - Lucking , et al. December 23, 2 | 2014-12-23 |
4-aryl-n-phenyl-1,3,5-triazin-2-amines Containing A Sulfoximine Group App 20140315906 - Lucking; Ulrich ;   et al. | 2014-10-23 |
18-methyl-6,7-methylene-3-oxo-17-pregn-4-ene-21,17b-carbolactones, Pharmaceutical Preparations Comprising Said Compounds And Use Thereof In The Treatment Of Endometriosis App 20140288035 - Hubner; Jan ;   et al. | 2014-09-25 |
Disubstituted 5-fluoro-pyrimidines App 20140228387 - Lucking; Ulrich ;   et al. | 2014-08-14 |
6 Substituted Imidazopyrazines For Use As Mps-1 And Tkk Inhibitors In The Treatment Of Hyperproliferative Disorders App 20140187548 - Koppitz; Marcus ;   et al. | 2014-07-03 |
6-substituted Imidazopyrazines For Use As Mps-1 And Tkk Inhibitors In The Treatment Of Hyperproliferative Disorders App 20140135319 - Koppitz; Marcus ;   et al. | 2014-05-15 |
Substituted 4-aryl-n-phenyl-1,3,5-triazin-2-amines App 20140045852 - Lucking; Ulrich ;   et al. | 2014-02-13 |
15, 16-methylene-17-(1'-propenyl)-17,3'-oxidoestra-4-en-3-one derivative, use thereof, and medicament containing said derivative Grant 8,623,850 - Klar , et al. January 7, 2 | 2014-01-07 |
Substituted Imidazopyridazines App 20130338133 - Klar; Ulrich ;   et al. | 2013-12-19 |
Imidazopyrazines For Use As Mps-1 And Tkk Inhibitors In The Treatment Hyperproliferative Disorders App 20130303532 - Koppitz; Marcus ;   et al. | 2013-11-14 |
6-thio-substituted Imidazopyrazines For Use As Mps-1 And Tkk Inhibitors In The Treatment Of Hyperproliferative Disorders App 20130281460 - Koppitz; Marcus ;   et al. | 2013-10-24 |
Substituted 6-imidazopyrazines For Use As Mps-1 And Tkk Inhibitors In The Treatment Of Hyperproliferative Disorders App 20130267527 - Koppitz; Marcus ;   et al. | 2013-10-10 |
6,7-dihydro-5h-benzo[7]annulene Derivatives, Process For Preparation Thereof, Pharmaceutical Preparations Comprising Them, And The Use Thereof For Production Of Medicaments App 20130252890 - Wintermantel; Tim ;   et al. | 2013-09-26 |
Substituted Imidazopyrazines App 20130210815 - Klar; Ulrich ;   et al. | 2013-08-15 |
Imidazopyrazines App 20130195848 - Klar; Ulrich ;   et al. | 2013-08-01 |
18-methyl-19-nor-17-pregn-4-ene-21,17-carbolactones, as well as pharmaceutical preparations that contain the latter Grant 8,445,469 - Bohlmann , et al. May 21, 2 | 2013-05-21 |
19-NOR-STEROID DERIVATIVES WITH A 15a,16a-METHYLENE GROUP AND A SATURATED 17,17-SPIROLACTONE RING, USE THEREOF, AND MEDICAMENTS CONTAINING SAID DERIVATIVES App 20130123219 - KLAR; Ulrich ;   et al. | 2013-05-16 |
17.beta.-cyano-19-nor-androst-4-ene derivative, its use and medicaments comprising the derivative Grant 8,207,150 - Kuhnke , et al. June 26, 2 | 2012-06-26 |
17Beta-Alkyl-17Alpha-oxy-estratrienes App 20120157421 - Bohlmann; Rolf ;   et al. | 2012-06-21 |
C-ring-substituted pregn-4-ene-21,17-carbolactones, and pharmaceutical preparations comprising the same App 20110130371 - Ring; Sven ;   et al. | 2011-06-02 |
Novel Anthranilamide Pyridinureas As Vascular Endothelial Growth Factor (vegf) Receptor Kinase Inhibitors App 20110124680 - BOHLMANN; Rolf ;   et al. | 2011-05-26 |
Nicotinamide pyridinureas as vascular endothelial growth factor (VEGF) receptor kinase inhibitors Grant 7,906,533 - Bohlmann , et al. March 15, 2 | 2011-03-15 |
Anthranilamide pyridinureas as vascular endothelial growth factor (VEGF) receptor kinase inhibitors Grant 7,902,229 - Bohlmann , et al. March 8, 2 | 2011-03-08 |
17-hydroxy-19-nor-21-carboxylic Acid-steroid Y-lactone Derivative, Use Thereof, And Medicament Containing The Derivative App 20110021472 - Klar; Ulrich ;   et al. | 2011-01-27 |
15,16-Methylene-17-hydroxy-19-nor-21-carboxylic acid-steroid Y-lactone derivative, use thereof and medicinal products containing the derivative App 20110015162 - Klar; Ulrich ;   et al. | 2011-01-20 |
11b-fluoro-3-acetoxyestra-3,5-dien-17-one And Method For The Production Thereof App 20110009654 - Petrov; Orlin ;   et al. | 2011-01-13 |
15, 16-methylene-17-(1'-propenyl)-17,3'-oxidoestra-4-en-3-one Derivative , Use Thereof, And Medicament Containing Said Derivative App 20110003779 - Klar; Ulrich ;   et al. | 2011-01-06 |
17-(1'propenyl)-17-3'-oxidoestra-4-en-3-one Derivative, Use Thereof, And Medicament Containing Said Derivative App 20100317632 - Klar; Ulrich ;   et al. | 2010-12-16 |
19-nor-steroid Derivatives With A 15alpha, 16alpha-methylene Group And A Saturated 17, 17-spiro-lactone Ring, Use Thereof, And Medicaments Containing Said Derivatives App 20100311702 - Klar; Ulrich ;   et al. | 2010-12-09 |
18-Methyl-19-norandrost-4-ene 17, 17-spiro ether (18-methyl-19-nor-20-spirox-4-en-3-one), and pharmaceutical products comprising the same Grant 7,846,917 - Bohlmann , et al. December 7, 2 | 2010-12-07 |
17beta-cyano-19-androst-4-ene Derivative, Its Use And Medicaments Comprising The Derivative App 20100292184 - Kuhnke; Joachim ;   et al. | 2010-11-18 |
Anthranilamide pyridinureas as vascular endothelial growth factor (VEGF) receptor kinase inhibitors Grant 7,572,794 - Bohlmann , et al. August 11, 2 | 2009-08-11 |
17.alpha.-alkyl-17.beta.-oxy-estratrienes and intermediate products for their production, use of the 17.alpha.-alkyl-17.beta.-oxy-estratrienes for the production of pharmaceutical agents as well as pharmaceutical preparations Grant 7,538,100 - Bohlmann , et al. May 26, 2 | 2009-05-26 |
Benzocycloheptene Derivatives As Estrogens Having Selective Activity App 20090099250 - WYRWA; Ralf ;   et al. | 2009-04-16 |
17Beta-CYANO-19-NOR-ANDROST-4-ENE DERIVATIVE, ITS USE AND MEDICAMENTS COMPRISING THE DERIVATIVE App 20090048217 - KUHNKE; Joachim ;   et al. | 2009-02-19 |
17Beta-CYANO-18A-HOMO-19-NOR-ANDROST-4-ENE DERIVATIVE, ITS USE AND MEDICAMENTS COMPRISING THE DERIVATIVE App 20090048218 - KUHNKE; JOACHIM ;   et al. | 2009-02-19 |
18-methyl-19-nor-17-pregn-4-ene-21,17-carbolactones, As Well As Pharmaceutical Preparations That Contain The Latter App 20090029953 - Bohlmann; Rolf ;   et al. | 2009-01-29 |
Process For Preparing 17alpha-acetoxy-6-methylenepregn-4-ene-3,20-dione, Medroxyprogesterone Acetate And Megestrol Acetate App 20090012321 - ANNEN; Klaus ;   et al. | 2009-01-08 |
18-Methyl-19-norandrost-4-ene 17, 17-spiro ether (18-methyl-19-nor-20-spirox-4-en-3-one), and pharmaceutical products comprising the same App 20080153787 - BOHLMANN; Rolf ;   et al. | 2008-06-26 |
8.beta.-vinyl-11.beta.-(.omega.-substituted)alkyl-estra-1,3,5(10)-trienes Grant 7,375,098 - Braeuer , et al. May 20, 2 | 2008-05-20 |
Androgenic 7-substituted 11-halogen steroids Grant 7,361,645 - Bohlmann , et al. April 22, 2 | 2008-04-22 |
Microbiological process for the production of 7-substitued 11-hydroxy steroids, 7,17-substituted 11-halogen steroids, and uses thereof App 20070298456 - Zorn; Lud-wig ;   et al. | 2007-12-27 |
Use of 8-Prenylnaringenin for Hormone Replacement Therapy App 20070276032 - Huempel; Michael ;   et al. | 2007-11-29 |
Microbiological process for the production of 7-substituted 11-hydroxy steroids, 7,17-substituted 11-Halogen steroids and uses thereof Grant 7,262,023 - Zorn , et al. August 28, 2 | 2007-08-28 |
Vegfr-2 and vegfr-3 inhibitory anthranilamide pyridones App 20070135489 - Huth; Andreas ;   et al. | 2007-06-14 |
VEGFR-2 and VEGFR-3 inhibitory anthranilamide pyridones Grant 7,202,260 - Huth , et al. April 10, 2 | 2007-04-10 |
Benzocycloheptenes, process for their production, pharmaceutical preparations that contain that latter as well as their use for the production of pharmaceutical agents Grant 7,145,015 - Bohlmann , et al. December 5, 2 | 2006-12-05 |
Novel anthranilamide pyridinureas as vascular endothelial growth factor (VEGF) receptor kinase inhibitors App 20060264425 - Bohlmann; Rolf ;   et al. | 2006-11-23 |
18-Methyl-19-nor-17-pregn-4-ene-21,17-carbolactones, as well as pharmaceutical preparations that contain the latter App 20060252737 - Bohlmann; Rolf ;   et al. | 2006-11-09 |
Novel nicotinamide pyridinureas as vascular endothelial growth factor (VEGF) receptor kinase inhibitors App 20060160861 - Bohlmann; Rolf ;   et al. | 2006-07-20 |
Antiestrogens, process for their production and their pharmaceutical use Grant 7,074,829 - Klar , et al. July 11, 2 | 2006-07-11 |
Novel anthranilamide pyridinureas as vascular endothelial growth factor (VEGF) receptor kinase inhibitors App 20060116380 - Bohlmann; Rolf ;   et al. | 2006-06-01 |
Composition containing an androgenous 11b-halogen steroid and a progestational hormone, and male contraceptive based on said composition App 20060100180 - Nubbemeyer; Reinhard ;   et al. | 2006-05-11 |
17.alpha.-ALKYL-17.beta.-OXY-ESTRATRIENES AND INTERMEDIATE PRODUCTS FOR THEIR PRODUCTION, USE OF THE 17.alpha.-ALKYL-17.beta.-OXY-ESTRATRIENES FOR THE PRODUCTION OF PHARMACEUTICAL AGENTS AS WELL AS PHARMACEUTICAL PREPARATIONS Grant 7,018,994 - Bohlmann , et al. March 28, 2 | 2006-03-28 |
17alpha-alkyl-17beta-oxy-estratrienes and intermediate products for their production, use of the 17alpha-alkyl-17beta-oxy-estratrienes for the production of pharmaceutical agents as well as pharmaceutical preparations App 20060009436 - Bohlmann; Rolf ;   et al. | 2006-01-12 |
11.beta.-Substituted 19-nor-17-.alpha.-pregna-1,3,5(10)-trien-17.beta.-ols with a 21,16.alpha.-lactone ring Grant 6,956,031 - Hillisch , et al. October 18, 2 | 2005-10-18 |
Benzocycloheptenes, process for their production, pharmaceutical preparations that contain the latter as well as their use for the production of pharmaceutical agents App 20050182081 - Bohlmann, Rolf ;   et al. | 2005-08-18 |
Microbiological process for the production of 7-substituted 11-hydroxy steroids, 7,17-substituted 11-halogen steroids that can be produced therefrom, their process for production and use as well as pharmaceutical prepartions that contain these compounds, as well as 7-substituted estra-1,3,5(10)-trie App 20050090477 - Zorn, Ludwig ;   et al. | 2005-04-28 |
Benzocycloheptenes, process for their production, pharmaceutical preparations that contain the latter as well as their use for the production of pharmaceutical agents Grant 6,878,750 - Bohlmann , et al. April 12, 2 | 2005-04-12 |
Androgenic 7-substituted 11-halogen steroids App 20050075322 - Bohlmann, Rolf ;   et al. | 2005-04-07 |
8beta-Vinyl-11beta-(omega-substituted)alkyl-estra-1,3,5(10)-trienes App 20050065135 - Braeuer, Nico ;   et al. | 2005-03-24 |
VEGFR-2 and VEGFR-3 inhibitory anthranilamide pyridones App 20050049281 - Huth, Andreas ;   et al. | 2005-03-03 |
11.beta. LONG-CHAIN SUBSTITUTED ESTRATRIENES, METHOD FOR THEIR PRODUCTION, PHARMACEUTICAL PREPARATIONS CONTAINING SAID 11.beta. LONG-CHAIN SUBSTITUTED ESTATRIENES, AND THEIR USE FOR PRODUCING MEDICAMENTS Grant 6,790,842 - Bohlmann , et al. September 14, 2 | 2004-09-14 |
11.beta.-HALOGEN-7.alpha.-SUBSTITUTED ESTRATRIENES, PROCESS FOR THE PRODUCTION OF PHARMACEUTICAL PREPARATIONS THAT CONTAIN THESE 11.beta.-HALOGEN-7.alpha.-SUBSTITUTED ESTRATRIENES AS WELL AS THEIR USE FOR THE PRODUCTION OF PHARMACEUTICAL AGENTS Grant 6,780,855 - Bohlmann , et al. August 24, 2 | 2004-08-24 |
11-Beta substituted 19-nor-17-alpha-pregna-1,3,5(10)-trien-17beta-ols with a 21,16alpha-lactone ring App 20040014735 - Hillisch, Alexander ;   et al. | 2004-01-22 |
17alpha-alkyl-17beta-oxy-estratrienes and intermediate products for their production, use of the 17alpha-alkyl-17beta-oxy-estratrienes for the production of pharmaceutical agents as well as pharmaceutical preparations App 20030191099 - Bohlmann, Rolf ;   et al. | 2003-10-09 |
New antiestrogens, process for their production and their pharmaceutical use App 20030162830 - Klar, Ulrich ;   et al. | 2003-08-28 |
11beta-halogen-7alpha-substituted Estratrienes, Metod For Producing Pharmaceutical Preparations Containing Said 11beta-halogen-7alpha- Substituted Estratrienes And Use Of The Same For Producing Medicaments App 20030069434 - BOHLMANN, ROLF ;   et al. | 2003-04-10 |
Benzocycloheptenes, process for their production, pharmaceutical preparations that contain the latter as well as their use for the production of pharmaceutical agents App 20030050324 - Bohlmann, Rolf ;   et al. | 2003-03-13 |
Benzocycloheptenes, process for their production, pharmaceutical preparations that contain the latter as well as their use for the production of pharmaceutical agents Grant 6,495,607 - Bohlmann , et al. December 17, 2 | 2002-12-17 |
Benzocycloheptenes, Process For Their Production, Pharmaceutical Preparations That Contain The Latter As Well As Their Use For The Production Of Pharmaceutical Agents App 20020068765 - BOHLMANN, ROLF ;   et al. | 2002-06-06 |
7 .alpha.-(5-methylaminopentyl)-estratrienes, process for their production, pharmaceutical preparations that contain these 7 .alpha.(5-methylaminopentyl)-estratrienes as well as their use for the production of pharmaceutical agents Grant 6,288,051 - Bittler , et al. September 11, 2 | 2001-09-11 |
7.alpha.-(xi-aminoalkyl)-estratrienes, process for their production, pharmaceutical preparations which contain these 7.alpha.-(xi-aminoalkyl-estratrienes as well as their use for the production of pharmaceutical agents Grant 6,271,403 - Bohlmann , et al. August 7, 2 | 2001-08-07 |
7.alpha.-(.xi.-aminoalkyl)-estratrienes, process for their production, pharmaceutical preparations which contain these 7.alpha.-(.xi.-aminoalkyl)-estratrienes as well as their use for the production of pharmaceutical agents Grant 5,866,560 - Bohlmann , et al. February 2, 1 | 1999-02-02 |
Triphenylethylenes, process for their production, pharmaceutical preparations that contain these triphenylethylenes as well as their use for the production of pharmaceutical agents Grant 5,807,899 - Bohlmann , et al. September 15, 1 | 1998-09-15 |
11.beta.-substituted 14,17-ethanoestratrienes, process for their production and their use as pharmaceutical agents Grant 5,502,046 - Bohlmann , et al. March 26, 1 | 1996-03-26 |
N-substituted imidazoles, as well as their use in pharmaceutical agents Grant 5,021,434 - Strehlke , et al. June 4, 1 | 1991-06-04 |
3-methylene-4-androsten-17-ones, process for their production and pharmaceutical preparations containing them Grant 4,925,834 - Bohlmann , et al. May 15, 1 | 1990-05-15 |
N-substituted imidazoles as aromatase inhibitors Grant 4,916,144 - Strehlke , et al. April 10, 1 | 1990-04-10 |