Patent | Date |
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Crystal Forms of (S)-4-(8-amino-3-(1-(but-2-ynoyl)-pyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1- -yl)-n-(pyridin-2-yl)benzamide App 20220177476 - Blatter; Frtiz ;   et al. | 2022-06-09 |
Therapeutic Combinations of a BTK Inhibitor, a PI3K Inhibitor, a JAK-2 Inhibitor, and/or a BCL-2 Inhibitor App 20220088013 - Hamdy; Ahmed ;   et al. | 2022-03-24 |
BTK Inhibitors to Treat Solid Tumors Through Modulation of the Tumor Microenvironment App 20210346382 - Hamdy; Ahmed ;   et al. | 2021-11-11 |
Therapeutic combinations of a BTK inhibitor, a PI3K inhibitor, a JAK-2 inhibitor, and/or a BCL-2 inhibitor Grant 11,166,951 - Hamdy , et al. November 9, 2 | 2021-11-09 |
Imidazopyrazine inhibitors of Bruton's tyrosine kinase Grant 11,110,088 - Barf , et al. September 7, 2 | 2021-09-07 |
Methods of treating chronic lymphocytic leukemia and small lymphocytic leukemia using a BTK inhibitor Grant 11,090,302 - Hamdy , et al. August 17, 2 | 2021-08-17 |
Crystal forms of (S)-4-(8-amino-3-(1-(but-2-ynoyl)pyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1-- yl)-N-(pyridin-2-yl)benzamide maleate Grant 11,059,829 - Blatter , et al. July 13, 2 | 2021-07-13 |
Imidazopyrazine Inhibitors of Bruton's Tyrosine Kinase App 20200330461 - Barf; Tjeerd ;   et al. | 2020-10-22 |
Crystal Forms of (S)-4-(8-amino-3-(1-(but-2-ynoyl)-pyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1- -yl)-N-(pyridin-2-yl)benzamide malea App 20200255437 - Kind Code | 2020-08-13 |
Imidazopyrazine inhibitors of Bruton's tyrosine kinase Grant 10,736,893 - Barf , et al. A | 2020-08-11 |
Pharmaceutical composition comprising a crystal form of (S)-4-(8-amino-3-(1-(but-2-ynoyl)pyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1-- yl)-N-(pyridin-2-yl)benzamide for treating diffuse large B-cell lymphoma Grant 10,640,509 - Blatter , et al. | 2020-05-05 |
Therapeutic Combinations of an IRAK4 Inhibitor and a BTK Inhibitor App 20200069668 - Lannutti; Brian ;   et al. | 2020-03-05 |
Therapeutic Combinations of a BTK Inhibitor, a PI3K Inhibitor, a JAK-2 Inhibitor, a PD-1 Inhibitor, and/or a PD-L1 Inhibitor App 20200069796 - Hamdy; Ahmed ;   et al. | 2020-03-05 |
BTK Inhibitors to Treat Solid Tumors Through Modulation of the Tumor Microenvironment App 20190381044 - Hamdy; Ahmed ;   et al. | 2019-12-19 |
Compositions and Methods for the Assessment of Drug Target Occupancy for Bruton's Tyrosine Kinase App 20190376971 - Barf; Tjeerd ;   et al. | 2019-12-12 |
Therapeutic Combination of a PI3K Inhibitor and a BTK Inhibitor App 20190358235 - HAMDY; Ahmed ;   et al. | 2019-11-28 |
Solid Forms and Formulations of Imidazopyrazine Compound App 20190337949 - Blatter; Fritz ;   et al. | 2019-11-07 |
Methods of Treating Chronic Lymphocytic Leukemia and Small Lymphocytic Leukemia Using a BTK Inhibitor App 20190290644 - Hamdy; Ahmed ;   et al. | 2019-09-26 |
Therapeutic combination of PI3K inhibitor and a BTK inhibitor Grant 10,328,080 - Hamdy , et al. | 2019-06-25 |
Methods of treating chronic lymphocytic leukemia and small lymphocytic leukemia using a BTK inhibitor Grant 10,272,083 - Hamdy , et al. | 2019-04-30 |
Pharmaceutical composition comprising a crystal form of (S)-4-(8-amino-3-(1-(but-2-ynoyl) pyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1-yl)-N-(pyridin-2-yl)benzamide Grant 10,167,291 - Blatter , et al. J | 2019-01-01 |
BTK Inhibitors to Treat Solid Tumors Through Modulation of the Tumor Microenvironment App 20180369244 - Hamdy; Ahmed ;   et al. | 2018-12-27 |
Imidazopyrazine Inhibitors of Bruton's Tyrosine Kinase App 20180318297 - Barf; Tjeerd ;   et al. | 2018-11-08 |
Therapeutic Combinations of a BTK Inhibitor, a PI3K Inhibitor, a JAK-2 Inhibitor, and/or a BCL-2 Inhibitor App 20180250298 - Hamdy; Ahmed ;   et al. | 2018-09-06 |
Therapeutic Combinations of a BTK Inhibitor, a PI3K Inhibitor, a JAK-2 Inhibitor, and/or a CDK4/6 Inhibitor App 20180250400 - Hamdy; Ahmed ;   et al. | 2018-09-06 |
Solid Forms and Formulations of Imidazopyrazine Compound App 20180208596 - Blatter; Fritz ;   et al. | 2018-07-26 |
Therapeutic Combinations of a BTK Inhibitor, a PI3K Inhibitor and/or a JAK-2 Inhibitor App 20180207154 - Hamdy; Ahmed ;   et al. | 2018-07-26 |
Therapeutic combinations of a BTK inhibitor, a PI3K inhibitor and/or a JAK-2 inhibitor Grant 9,949,971 - Hamdy , et al. April 24, 2 | 2018-04-24 |
Crystal forms of (S)-4-(8-amino-3-(1-(but-2-ynoyl)pyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1-- yl)-N-(pyridin-2-yl)benzamide Grant 9,796,721 - Blatter , et al. October 24, 2 | 2017-10-24 |
Therapeutic Combination of PI3K Inhibitor and a BTK Inhibitor App 20170266191 - Hamdy; Ahmed ;   et al. | 2017-09-21 |
Therapeutic Combinations of a BTK Inhibitor, a PI3K Inhibitor, a JAK-2 Inhibitor, a PD-1 Inhibitor, and/or a PD-L1 Inhibitor App 20170239351 - Hamdy; Ahmed ;   et al. | 2017-08-24 |
BTK Inhibitors to Treat Solid Tumors Through Modulation of the Tumor Microenvironment App 20170231995 - Hamdy; Ahmed ;   et al. | 2017-08-17 |
Therapeutic Combinations of a BTK Inhibitor, a PI3K Inhibitor, a JAK-2 Inhibitor, and/or a BCL-2 Inhibitor App 20170231986 - Hamdy; Ahmed ;   et al. | 2017-08-17 |
Therapeutic Combinations of a BTK Inhibitor, a PI3K Inhibitor, a JAK-2 Inhibitor, and/or a CDK 4/6 Inhibitor App 20170224819 - Hamdy; Ahmed ;   et al. | 2017-08-10 |
Therapeutic Combinations of a BTK Inhibitor, a PI3K Inhibitor and/or a JAK-2 Inhibitor App 20170136014 - Hamdy; Ahmed ;   et al. | 2017-05-18 |
Methods of Treating Chronic Lymphocytic Leukemia and Small Lymphocytic Leukemia Using a BTK Inhibitor App 20170095471 - Ahmed; Hamdy ;   et al. | 2017-04-06 |
Therapeutic Combinations of an IRAK4 Inhibitor and a BTK Inhibitor App 20170035881 - Lannutti; Brian ;   et al. | 2017-02-09 |
Solid Forms and Formulations of Imidazopyrazine Compound App 20170029428 - Blatter; Fritz ;   et al. | 2017-02-02 |
Inhibitors Of 11-beta-hydroxy Steriod Dehydrogenase Type 1 App 20100113435 - BARF; Tjeerd ;   et al. | 2010-05-06 |
Inhibitors of 11-.beta.-hydroxy steroid dehydrogenase type 1 Grant 7,671,051 - Barf , et al. March 2, 2 | 2010-03-02 |
Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 Grant 7,618,961 - Barf , et al. November 17, 2 | 2009-11-17 |
New compounds App 20070004765 - Graffner-Nordberg; Malin ;   et al. | 2007-01-04 |
Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 App 20060287374 - Barf; Tjeerd ;   et al. | 2006-12-21 |
Inhibitors of 11-.beta.-hydroxy steroid dehydrogenase type 1 Grant 7,125,900 - Barf , et al. October 24, 2 | 2006-10-24 |
Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 Grant 7,094,792 - Barf , et al. August 22, 2 | 2006-08-22 |
Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 App 20060160797 - Nilsson; Marianne ;   et al. | 2006-07-20 |
Inhibitors of 11-.beta.-hydroxy steroid dehydrogenase type 1 Grant 7,030,135 - Nilsson , et al. April 18, 2 | 2006-04-18 |
Inhibitors of 11-beta-hydroxy steriod dehydrogenase type 1 App 20050250776 - Barf, Tjeerd ;   et al. | 2005-11-10 |
New compounds App 20050239853 - Barf, Tjeerd ;   et al. | 2005-10-27 |
Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 App 20040224996 - Barf, Tjeerd ;   et al. | 2004-11-11 |
Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 App 20030199501 - Nilsson, Marianne ;   et al. | 2003-10-23 |
Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 App 20030176476 - Barf, Tjeerd ;   et al. | 2003-09-18 |
Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 App 20030130318 - Barf, Tjeerd ;   et al. | 2003-07-10 |
Inhibitors of protein tyrosine phosphatase Grant 6,410,585 - Larsen , et al. June 25, 2 | 2002-06-25 |