Patent | Date |
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Compounds And Methods Useful For Modulating Gene Splicing App 20220282249 - Agrawal; Sudhir | 2022-09-08 |
Ube3a Antisense Therapeutics App 20220259601 - Fink; James ;   et al. | 2022-08-18 |
Therapeutic Compositions For Treating Pain Via Multiple Targets App 20220112496 - Dempsey; Graham T. ;   et al. | 2022-04-14 |
Immune Modulation With Tlr9 Agonists For Cancer Treatment App 20220088054 - AGRAWAL; Sudhir ;   et al. | 2022-03-24 |
Antisense Oligonucleotides For Allele Specificity App 20220073932 - Agrawal; Sudhir | 2022-03-10 |
Immune modulation with TLR9 agonists for cancer treatment Grant 11,224,611 - Agrawal , et al. January 18, 2 | 2022-01-18 |
Immune Modulation With Tlr9 Agonists For Cancer Treatment App 20210052625 - AGRAWAL; Sudhir ;   et al. | 2021-02-25 |
Immune Modulation With Tlr9 Agonists For Cancer Treatment App 20210038630 - AGRAWAL; Sudhir ;   et al. | 2021-02-11 |
Immune modulation with TLR9 agonists for cancer treatment Grant 10,835,550 - Agrawal , et al. November 17, 2 | 2020-11-17 |
Immune modulation with TLR9 agonists for cancer treatment Grant 10,772,907 - Agrawal , et al. Sept | 2020-09-15 |
Immune Modulation With Tlr9 Agonists For Cancer Treatment App 20200138848 - AGRAWAL; Sudhir ;   et al. | 2020-05-07 |
Treatment Of Cancer Using Tlr9 Agonist With Checkpoint Inhibitors App 20200101102 - WANG; Daqing ;   et al. | 2020-04-02 |
Immune Modulation With Tlr9 Agonists For Cancer Treatment App 20200054663 - AGRAWAL; Sudhir ;   et al. | 2020-02-20 |
Immune modulation with TLR9 agonists for cancer treatment Grant 10,463,686 - Agrawal , et al. No | 2019-11-05 |
Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response Grant 10,066,230 - Kandimalla , et al. September 4, 2 | 2018-09-04 |
Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response Grant 10,041,076 - Kandimalla , et al. August 7, 2 | 2018-08-07 |
Immune Modulation With Tlr9 Agonists For Cancer Treatment App 20180125877 - AGRAWAL; Sudhir ;   et al. | 2018-05-10 |
Compositions For Inhibiting Checkpoint Gene Expression And Uses Thereof App 20180044669 - AGRAWAL; Sudhir ;   et al. | 2018-02-15 |
Immune Regulatory Oligonucleotide (iro) Compounds To Modulate Toll-like Receptor Based Immune Response App 20180023085 - Kandimalla; Ekambar R. ;   et al. | 2018-01-25 |
Compositions for inhibiting checkpoint gene expression and uses thereof Grant 9,828,601 - Agrawal , et al. November 28, 2 | 2017-11-28 |
Treatment Of Cancer Using Tlr9 Agonist With Checkpoint Inhibitors App 20170274004 - Wang; Daqing ;   et al. | 2017-09-28 |
Toll-like Receptor 9 Antagonist And Methods Of Use Thereof App 20170268006 - Agrawal; Sudhir ;   et al. | 2017-09-21 |
Immune Regulatory Oligonucleotide (iro) Compounds To Modulate Toll-like Receptor Based Immune Response App 20170233741 - Kandimalla; Ekambar R. ;   et al. | 2017-08-17 |
Toll-like receptor 9 antagonist and methods of use thereof Grant 9,688,993 - Agrawal , et al. June 27, 2 | 2017-06-27 |
Immune Regulatory Oligonucleotide (iro) Compounds To Modulate Toll-like Receptor Based Immune Response App 20170145417 - Kandimalla; Ekambar R. ;   et al. | 2017-05-25 |
Compositions For Inhibiting Nlrp3 Gene Expression And Uses Thereof App 20170145412 - Jiang; Weiwen ;   et al. | 2017-05-25 |
Compositions For Inhibiting Dux4 Gene Expression And Uses Thereof App 20170009230 - Agrawal; Sudhir ;   et al. | 2017-01-12 |
Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response Grant 9,540,651 - Kandimalla , et al. January 10, 2 | 2017-01-10 |
Immune Regulatory Oligonucleotide (iro) Compounds To Modulate Toll-like Receptor Based Immune Response App 20160312225 - Kandimalla; Ekambar R. ;   et al. | 2016-10-27 |
Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response Grant 9,453,228 - Kandimalla , et al. September 27, 2 | 2016-09-27 |
Compositions For Inhibiting Checkpoint Gene Expression And Uses Thereof App 20160251652 - Agrawal; Sudhir ;   et al. | 2016-09-01 |
Toll-like Receptor 9 Antagonist And Methods Of Use Thereof App 20160237437 - Agrawal; Sudhir ;   et al. | 2016-08-18 |
Immune Regulatory Oligonucleotide (iro) Compounds To Modulate Toll-like Receptor Based Immune Response App 20160215287 - Kandimalla; Ekambar R. ;   et al. | 2016-07-28 |
Immune Regulatory Oligonucleotide (iro) Compounds To Modulate Toll-like Receptor Based Immune Response App 20160201060 - Kandimalla; Ekambar ;   et al. | 2016-07-14 |
Immune Regulatory Oligonucleotide (iro) Compounds To Modulate Toll-like Receptor Based Immune Response App 20160138022 - Kandimalla; Ekambar R. ;   et al. | 2016-05-19 |
Treatment Of Cancer Using Tlr9 Agonist With Checkpoint Inhibitors App 20160101128 - Wang; Daqing ;   et al. | 2016-04-14 |
Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response Grant 9,260,719 - Kandimalla , et al. February 16, 2 | 2016-02-16 |
Stabilized immune modulatory RNA (SIMRA) compounds for TLR7 and TLR8 Grant 9,243,050 - Kandimalla , et al. January 26, 2 | 2016-01-26 |
Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response Grant 9,206,430 - Kandimalla , et al. December 8, 2 | 2015-12-08 |
Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response Grant 9,096,858 - Kandimalla , et al. August 4, 2 | 2015-08-04 |
Potentiation of autoimmune and inflammatory disease treatments by immune regulatory oligonucleotide (IRO) antagonists of TLR7 and TLR9 Grant 8,987,221 - Zhu , et al. March 24, 2 | 2015-03-24 |
Compositions for Inhibiting Gene Expression and Uses Thereof App 20150044196 - Agrawal; Sudhir ;   et al. | 2015-02-12 |
Stabilized immunomodulatory oligonucleotides Grant 8,946,175 - Kandimalla , et al. February 3, 2 | 2015-02-03 |
Compositions for inhibiting gene expression and uses thereof Grant 8,877,722 - Agrawal , et al. November 4, 2 | 2014-11-04 |
Stabilized Immune Modulatory Rna (simra) Compounds For Tlr7 And Tlr8 App 20140308300 - Kandimalla; Ekambar R. ;   et al. | 2014-10-16 |
Use of inhibitors of toll-like receptors in the prevention and treatment of hypercholesterolemia and hyperlipidemia and diseases related thereto Grant 8,853,177 - Zhu , et al. October 7, 2 | 2014-10-07 |
Toll like receptor modulators Grant 8,853,375 - Kandimalla , et al. October 7, 2 | 2014-10-07 |
Immune Regulatory Oligonucleotide (iro) Compounds To Modulate Toll-like Receptor Based Immune Response App 20140193396 - Kandimalla; Ekambar R. ;   et al. | 2014-07-10 |
Stabilized immune modulatory RNA (SIMRA) compounds for TLR7 and TLR8 Grant 8,759,310 - Kandimalla , et al. June 24, 2 | 2014-06-24 |
Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes Grant 8,716,253 - Kandimalla , et al. May 6, 2 | 2014-05-06 |
Immune Regulatory Oligonucleotide (iro) Compounds To Modulate Toll-like Receptor Based Immune Response App 20140004100 - Kandimalla; Ekambar R. ;   et al. | 2014-01-02 |
Immune Regulatory Oligonucleotide (iro) Compounds To Modulate Toll-like Receptor Based Immune Response App 20130267583 - Kandimalla; Ekambar R. ;   et al. | 2013-10-10 |
Stabilized Immune Modulatory Rna (simra) Compounds For Tlr7 And Tlr8 App 20130202584 - Kandimalla; Ekambar R. ;   et al. | 2013-08-08 |
Agonists of toll-like receptor 3 and methods of their use Grant 8,492,358 - Kandimalla , et al. July 23, 2 | 2013-07-23 |
Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response Grant 8,486,908 - Kandimalla , et al. July 16, 2 | 2013-07-16 |
Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes Grant 8,476,416 - Kandimalla , et al. July 2, 2 | 2013-07-02 |
Compositions For Inhibiting Gene Expression And Uses Thereof App 20130142778 - AGRAWAL; SUDHIR ;   et al. | 2013-06-06 |
Compositions for inhibiting gene expression and uses thereof Grant 8,431,544 - Agrawal , et al. April 30, 2 | 2013-04-30 |
Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response Grant 8,426,375 - Kandimalla , et al. April 23, 2 | 2013-04-23 |
Immunostimulatory oligonucleotide multimers Grant 8,420,615 - Agrawal , et al. April 16, 2 | 2013-04-16 |
Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response Grant 8,399,423 - Kandimalla , et al. March 19, 2 | 2013-03-19 |
Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response Grant 8,383,598 - Kandimalla , et al. February 26, 2 | 2013-02-26 |
Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response Grant 8,377,898 - Kandimalla , et al. February 19, 2 | 2013-02-19 |
Stabilized immune modulatory RNA (SIMRA) compounds Grant 8,362,233 - Kandimalla , et al. January 29, 2 | 2013-01-29 |
Synthetic agonists of TLR9 Grant 8,361,986 - Kandimalla , et al. January 29, 2 | 2013-01-29 |
Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response Grant 8,357,665 - Kandimalla , et al. January 22, 2 | 2013-01-22 |
Modulation Of Immunostimulatory Properties Of Oligonucleotide-based Compounds By Utilizing Modified Immunostimulatory Dinucleotides App 20120201807 - Agrawal; Sudhir ;   et al. | 2012-08-09 |
Stabilized Immune Modulatory Rna (simra) Compounds App 20120183530 - Kandimalla; Ekambar ;   et al. | 2012-07-19 |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5' ends Grant 8,202,850 - Agrawal , et al. June 19, 2 | 2012-06-19 |
Synthetic RNA-based agonists of TLR7 Grant 8,202,974 - Lan , et al. June 19, 2 | 2012-06-19 |
Stabilized immune modulatory RNA (SIMRA) compounds Grant 8,188,261 - Kandimalla , et al. May 29, 2 | 2012-05-29 |
Immune Regulatory Oligonucleotide (iro) Compounds To Modulate Toll-like Receptor Based Immune Response App 20120128699 - Kandimalla; Ekambar R. ;   et al. | 2012-05-24 |
Synergistic Treatment Of Cancer Using Immunomers In Conjunction With Chemotherapeutic Agents App 20120107303 - Kandimalla; Ekambar R. ;   et al. | 2012-05-03 |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by utilizing modified immunostimulatory dinucleotides Grant 8,153,608 - Agrawal , et al. April 10, 2 | 2012-04-10 |
Modulation of toll-like receptor 3 expression by antisense oligonucleotides Grant 8,153,605 - Kandimalla , et al. April 10, 2 | 2012-04-10 |
Modulation of toll-like receptor 5 expression by antisense oligonucleotides Grant 8,153,777 - Kandimalla , et al. April 10, 2 | 2012-04-10 |
Novel Agonists Of Toll-like Receptor 3 And Methods Of Their Use App 20120034248 - KANDIMALLA; EKAMBAR R. ;   et al. | 2012-02-09 |
Stabilized immune modulatory RNA (SIMRA) compounds for TLR7 and TLR8 Grant 8,106,173 - Kandimalla , et al. January 31, 2 | 2012-01-31 |
Compositions For Inhibiting Gene Expression And Uses Thereof App 20120016004 - AGRAWAL; SUDHIR ;   et al. | 2012-01-19 |
Novel Synthetic Agonists Of Tlr9 App 20110311518 - KANDIMALLA; EKAMBAR R. ;   et al. | 2011-12-22 |
Immunostimulatory Properties Of Oligonucleotide-based Compounds Comprising Modified Immunostimulatory Dinucleotides App 20110305684 - Agrawal; Sudhir ;   et al. | 2011-12-15 |
Novel Synthetic Agonists Of Tlr9 App 20110293565 - Kandimalla; Ekambar ;   et al. | 2011-12-01 |
Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes Grant 8,030,462 - Kandimalla , et al. October 4, 2 | 2011-10-04 |
Modulation Of Immunostimulatory Properties Of Oligonucleotide-based Compounds By Optimal Presentation Of 5' Ends App 20110229456 - AGRAWAL; SUDHIR ;   et al. | 2011-09-22 |
Stabilized immunomodulatory oligonucleotides Grant 8,008,267 - Kandimalla , et al. August 30, 2 | 2011-08-30 |
Potentiation of Autoimmune and Inflammatory Disease Treatments by Immune Regulatory Oligonucleotide (IRO) Antagonists of TLR7 and TLR9 App 20110171209 - Zhu; Fu-Gang ;   et al. | 2011-07-14 |
Synergistic Stimulation Of The Immune System Using Immunostimulatory Oligonucleotides And/or Immunomer Compounds In Conjunction With Cytokines And/or Chemotherapeutic Agents Or Radiation Therapy App 20110158937 - Kandimalla; Ekambar ;   et al. | 2011-06-30 |
Modulation Of Immunostimulatory Properties Of Oligonucleotide-based Compounds By Utilizing Modified Immunostimulatory Dinucleotides App 20110150863 - Agrawal; Sudhir ;   et al. | 2011-06-23 |
Synthetic agonists of TLR9 Grant 7,960,362 - Kandimalla , et al. June 14, 2 | 2011-06-14 |
Synthetic Agonists Of Tlr9 App 20110135669 - KANDIMALLA; EKAMBAR ;   et al. | 2011-06-09 |
Potent Mucosal Immune Response Induced By Modified Immunomodulatory Oligonucleotides App 20110123540 - Wang; Daqing ;   et al. | 2011-05-26 |
Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes Grant 7,932,367 - Kandimalla , et al. April 26, 2 | 2011-04-26 |
Compositions For Inhibiting Gene Expression And Uses Thereof App 20110082186 - Agrawal; Sudhir ;   et al. | 2011-04-07 |
Modulation Of Oligonucleotide Cpg-mediated Immune Stimulation By Positional Modification Of Nucleosides App 20110059067 - AGRAWAL; SUDHIR | 2011-03-10 |
Synthetic agonists of TLR9 Grant 7,884,197 - Kandimalla , et al. February 8, 2 | 2011-02-08 |
Synergistic treatment of cancer using immunomers in conjunction with chemotherapeutic agents Grant 7,875,594 - Kandimalla , et al. January 25, 2 | 2011-01-25 |
Oligonucleotide-based Compounds As Inhibitors Of Toll-like Receptors App 20110009477 - Yu; Dong ;   et al. | 2011-01-13 |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by utilizing modified immunostimulatory dinucleotides Grant 7,863,250 - Agrawal , et al. January 4, 2 | 2011-01-04 |
Methods And Compositons For Antisense Vegf Oligonucleotides App 20100330152 - Gill; Parkash ;   et al. | 2010-12-30 |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by utilizing modified immunostimulatory dinucleotides Grant 7,851,453 - Agrawal , et al. December 14, 2 | 2010-12-14 |
Short immunomodulatory oligonucleotides Grant 7,851,454 - Agrawal , et al. December 14, 2 | 2010-12-14 |
Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes Grant 7,833,538 - Kandimalla , et al. November 16, 2 | 2010-11-16 |
Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes Grant 7,824,696 - Kandimalla , et al. November 2, 2 | 2010-11-02 |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5' ends Grant 7,812,000 - Agrawal , et al. October 12, 2 | 2010-10-12 |
Modulation of Immunostimulatory Properties of Oligonucleotide-Based Compounds by Optimal Presentation of 5' Ends App 20100254974 - Agrawal; Sudhir ;   et al. | 2010-10-07 |
Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes Grant 7,790,168 - Kandimalla , et al. September 7, 2 | 2010-09-07 |
Immunostimulatory activity of immune modulatory oligonucleotides (IMO.TM.) containing different lengths of palindromic segments Grant 7,786,089 - Kandimalla , et al. August 31, 2 | 2010-08-31 |
Synthetic Rna-based Agonists Of Tlr7 App 20100215642 - Lan; Tao ;   et al. | 2010-08-26 |
Immunostimulatory Activity Of Palindromic Immune Modulatory Oligonucleotides (imo) Containing Different Lengths Of Palindromic Segments App 20100215646 - Kandimalla; Ekambar R. ;   et al. | 2010-08-26 |
Immunostimulatory properties of oligonucleotide-based compounds comprising modified immunostimulatory dinucleotides Grant 7,776,834 - Agrawal , et al. August 17, 2 | 2010-08-17 |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5' ends Grant 7,749,975 - Agrawal , et al. July 6, 2 | 2010-07-06 |
Immunostimulatory Oligonucleotide Multimers App 20100166736 - Agrawal; Sudhir ;   et al. | 2010-07-01 |
Modulation of immunostimulatory properties by small oligonucleotide-based compounds App 20100166805 - Agrawal; Sudhir ;   et al. | 2010-07-01 |
Immunostimulatory Properties Of Oligonucleotide-based Compounds Comprising Modified Immunostimulatory Dinucleotides App 20100143328 - Agrawal; Sudhir ;   et al. | 2010-06-10 |
Modulation of immunostimulatory properties by small oligonucleotide-based compounds Grant 7,713,535 - Agrawal , et al. May 11, 2 | 2010-05-11 |
Modulation of Toll-Like Receptor 4 Expression by Antisense Oligonucleotides App 20100111936 - Putta; Mallikarjuna ;   et al. | 2010-05-06 |
Modulation of Toll-Like Receptor 2 Expression By Antisense Oligonucleotides App 20100111935 - Bhagat; Lakshmi ;   et al. | 2010-05-06 |
Modulation of Toll-Like Receptor 5 Expression by Antisense Oligonucleotides App 20100111937 - Kandimalla; Ekambar ;   et al. | 2010-05-06 |
Synergistic stimulation of the immune system using immunostimulatory oligonucleotides and/or immunomer compounds in conjunction with cytokines and/or chemotherapeutic agents or radiation therapy Grant 7,709,617 - Kandimalla , et al. May 4, 2 | 2010-05-04 |
Use of Inhibitors of Toll-Like Receptors in the Prevention and Treatment of Hypercholesterolemia and Hyperlipidemia and Diseases Related Thereto App 20100098685 - Zhu; Fu-Gang ;   et al. | 2010-04-22 |
Oligonucleotide mediated specific cytokine induction and prophylaxis and treatment of viral infection in a mammal Grant 7,700,570 - Agrawal , et al. April 20, 2 | 2010-04-20 |
Modulation Of Myeloid Differentation Primary Response Gene 88 (myd88) Expression By Antisense Oligonucleotides App 20100092486 - Kandimalla; Ekambar ;   et al. | 2010-04-15 |
Epidermal growth factor receptor antisense oligonucleotides Grant 7,671,035 - Agrawal , et al. March 2, 2 | 2010-03-02 |
Modulation Of Toll-like Receptor 8 Expression By Antisense Oligonucleotides App 20100047188 - Kandimalla; Ekambar ;   et al. | 2010-02-25 |
Modulation Of Toll-like Receptor 7 Expression By Antisense Oligonucleotides App 20100041734 - Kandimalla; Ekambar ;   et al. | 2010-02-18 |
Modulation Of Toll-like Receptor 3 Expression By Antisense Oligonucleotides App 20100041735 - Kandimalla; Ekambar ;   et al. | 2010-02-18 |
Modulation Of Toll-like Receptor 9 Expression By Antisense Oligonucleotides App 20100035967 - Kandimalla; Ekambar ;   et al. | 2010-02-11 |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by utilizing modified immunostimulatory dinucleotides Grant 7,632,822 - Agrawal , et al. December 15, 2 | 2009-12-15 |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by utilizing modified immunostimulatory dinucleotides Grant 7,595,305 - Agrawal , et al. September 29, 2 | 2009-09-29 |
Synergistic treatment of cancer using immunomers in conjunction with therapeutic agents Grant 7,569,554 - Kandimalla , et al. August 4, 2 | 2009-08-04 |
Immunostimulatory oligonucleotide multimers Grant 7,566,702 - Agrawal , et al. July 28, 2 | 2009-07-28 |
Immune Regulatory Oligonucleotide (iro) Compounds To Modulate Toll-like Receptor Based Immune Response App 20090098063 - Kandimalla; Ekambar R. ;   et al. | 2009-04-16 |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5' ends Grant 7,517,862 - Agrawal , et al. April 14, 2 | 2009-04-14 |
Immune Regulatory Oligonucleotide (iro) Compounds To Modulate Toll-like Receptor Based Immune Response App 20090087388 - Kandimalla; Ekambar ;   et al. | 2009-04-02 |
Immune Regulatory Oligonucleotide (iro) Compounds To Modulate Toll-like Receptor Based Immune Response App 20090081198 - Kandimalla; Ekambar ;   et al. | 2009-03-26 |
Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response App 20090060898 - Kandimalla; Ekambar R. ;   et al. | 2009-03-05 |
Immunostimulatory oligonucleotide multimers Grant 7,498,426 - Agrawal , et al. March 3, 2 | 2009-03-03 |
Immunostimulatory oligonucleotide multimers Grant 7,498,425 - Agrawal , et al. March 3, 2 | 2009-03-03 |
Stabilized Immune Modulatory Rna (simra) Compounds App 20090053205 - Kandimalla; Ekambar ;   et al. | 2009-02-26 |
Toll Like Receptor Modulators App 20090053148 - Kandimalla; Ekambar ;   et al. | 2009-02-26 |
Novel Synthetic Agonists Of Tlr9 App 20090053206 - Kandimalla; Ekambar R. ;   et al. | 2009-02-26 |
Short Immunomodulatory Oligonucleotides App 20090010938 - Agrawal; Sudhir ;   et al. | 2009-01-08 |
Immunostimulatory properties of oligonucleotide-based compounds comprising modified immunostimulatory dinucleotides Grant 7,470,674 - Agrawal , et al. December 30, 2 | 2008-12-30 |
Synthetic Agonists Of Tlr9 App 20080292648 - Kandimalla; Ekambar ;   et al. | 2008-11-27 |
Novel synthetic agonists of toll-like receptors containing CG dinucleotide modifications App 20080279785 - Kandimalla; Ekambar R. ;   et al. | 2008-11-13 |
Immunostimulatory oligonucleotide multimers Grant 7,427,405 - Agrawal , et al. September 23, 2 | 2008-09-23 |
Synergistic Treatment Of Cancer Using Immunomers In Conjunction With Chemotherapeutic Agents App 20080206265 - Kandimalla; Ekambar R. ;   et al. | 2008-08-28 |
Immunostimulatory Oligonucleotide Multimers App 20080193437 - Agrawal; Sudhir ;   et al. | 2008-08-14 |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5' ends Grant 7,407,944 - Agrawal , et al. August 5, 2 | 2008-08-05 |
Immunostimulatory oligonucleotide multimers Grant 7,405,285 - Agrawal , et al. July 29, 2 | 2008-07-29 |
Stabilized Immune Modulatory Rna (simra) Compounds For Tlr7 And Tlr8 App 20080171712 - Kandimalla; Ekambar R. ;   et al. | 2008-07-17 |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5' ends App 20080152662 - Agrawal; Sudhir ;   et al. | 2008-06-26 |
Immune Regulatory Oligonucleotide (iro) Compounds To Modulate Toll-like Receptor Based Immune Response App 20080089883 - Kandimalla; Ekambar R. ;   et al. | 2008-04-17 |
Short immunomodulatory oligonucleotides Grant 7,354,907 - Agrawal , et al. April 8, 2 | 2008-04-08 |
Modulation of oligonucleotide CpG-mediated immune stimulation by positional modification of nucleosides Grant 7,329,648 - Agrawal February 12, 2 | 2008-02-12 |
Modulation of immunostimulatory activity of immunostimulatory Oligonucleotide analogs by positional chemical changes App 20080027214 - Kandimalla; Ekambar R. ;   et al. | 2008-01-31 |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5' ends Grant 7,276,489 - Agrawal , et al. October 2, 2 | 2007-10-02 |
Immunostimulatory activity of immune modulatory oligonucleotides (IMOtm) containing different lengths of palindromic segments App 20070219153 - Kandimalla; Ekambar R. ;   et al. | 2007-09-20 |
Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes Grant 7,262,286 - Kandimalla , et al. August 28, 2 | 2007-08-28 |
Immunostimulatory oligonucleotide multimers App 20070179103 - Agrawal; Sudhir ;   et al. | 2007-08-02 |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5' ends App 20070173469 - Agrawal; Sudhir ;   et al. | 2007-07-26 |
Immunostimulatory properties of oligonucleotide-based compounds comprising modified immunostimulatory dinucleotides App 20070105801 - Agrawal; Sudhir ;   et al. | 2007-05-10 |
Immunostimulatory properties of oligonucleotide-based compounds comprising modified immunostimulatory dinucleotides App 20070105800 - Agrawal; Sudhir ;   et al. | 2007-05-10 |
Short immunomodulatory oligonucleotides App 20070093439 - Agrawal; Sudhir ;   et al. | 2007-04-26 |
Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes App 20070072198 - Kandimalla; Ekambar R. ;   et al. | 2007-03-29 |
Modulation of oligonucleotide CpG-mediated immune stimulation by positional modification of nucleosides Grant 7,176,296 - Agrawal , et al. February 13, 2 | 2007-02-13 |
HIV-specific synthetic oligonucleotides and methods of their use Grant 7,173,014 - Agrawal February 6, 2 | 2007-02-06 |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by utilizing modified immunostimulatory dinucleotides App 20060287261 - Agrawal; Sudhir ;   et al. | 2006-12-21 |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5' ends App 20060287262 - Agrawal; Sudhir ;   et al. | 2006-12-21 |
Modulation of oligonucleotide CpG-mediated immune stimulation by positional modification of nucleosides Grant 7,115,579 - Agrawal , et al. October 3, 2 | 2006-10-03 |
Synergisitic stimulation of the immune system using immunostimulatory oligonucleotides and/or immunomer compounds in conjunction with cytokines and/or chemotherapeutic agents or radiation therapy App 20060217328 - Kandimalla; Ekambar R. ;   et al. | 2006-09-28 |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by utilizing modified immunostimulatory dinucleotides App 20060211641 - Agrawal; Sudhir ;   et al. | 2006-09-21 |
Modulation of oligonucleotide CpG-mediated immune stimulation by positional modification of nucleosides Grant 7,105,495 - Agrawal , et al. September 12, 2 | 2006-09-12 |
Modified protein kinase A-specific oligonucleotides and methods of their use Grant 7,074,768 - Agrawal July 11, 2 | 2006-07-11 |
Modulation of oligonucleotide CpG-mediated immune stimulation by positional modification of nucleosides App 20060142556 - Agrawal; Sudhir | 2006-06-29 |
Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes App 20060142224 - Kandimalla; Ekambar R. ;   et al. | 2006-06-29 |
Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes App 20060135454 - Kandimalla; Ekambar R. ;   et al. | 2006-06-22 |
Synergistic inhibition of VEGF and modulation of the immune response App 20060105979 - Agrawal; Sudhir ;   et al. | 2006-05-18 |
Hybrid oligonucleotide phosphorothioates Grant 7,045,609 - Metelev , et al. May 16, 2 | 2006-05-16 |
Immunostimulatory oligonucleotide multimers App 20060094680 - Agrawal; Sudhir ;   et al. | 2006-05-04 |
Immunostimulatory oligonucleotide multimers App 20060094681 - Agrawal; Sudhir ;   et al. | 2006-05-04 |
Synergistic stimulation of the immune system using immunostimulatory oligonucleotides and/or immunomer compounds in conjunction with cytokines and/or chemotherapeutic agents or radiation therapy App 20060074040 - Kandimalla; Ekambar R. ;   et al. | 2006-04-06 |
Sensitization of cells to cytotoxic agents using oligonucleotides directed to nucleotide excision repair or transcritpion coupled repair genes App 20060052319 - Agrawal; Sudhir ;   et al. | 2006-03-09 |
Immunostimulatory oligonucleotide multimers App 20060025365 - Agrawal; Sudhir ;   et al. | 2006-02-02 |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by utilizing modified immunostimulatory dinucleotides App 20060019918 - Agrawal; Sudhir ;   et al. | 2006-01-26 |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5' ends App 20060019909 - Agrawal; Sudhir ;   et al. | 2006-01-26 |
Immunostimulatory oligonucleotide multimers App 20060019919 - Agrawal; Sudhir ;   et al. | 2006-01-26 |
Immunostimulatory oligonucleotide multimers App 20060014713 - Agrawal; Sudhir ;   et al. | 2006-01-19 |
Enhanced activity of HIV vaccine using a second generation immunomodulatory oligonucleotide App 20050266015 - Clerici, Mario ;   et al. | 2005-12-01 |
Potent mucosal immune response induced by modified immunomodulatory oligonucleotides App 20050222072 - Wang, Daqing ;   et al. | 2005-10-06 |
MDM2-specific antisense oligonucleotides Grant 6,946,447 - Chen , et al. September 20, 2 | 2005-09-20 |
Method of down-regulating gene expression Grant 6,936,593 - Agrawal , et al. August 30, 2 | 2005-08-30 |
Modulation of immunostimulatory properties by small oligonucleotide-based compounds App 20050130918 - Agrawal, Sudhir ;   et al. | 2005-06-16 |
Hybridization-based fluorescence assay App 20050089915 - Kandimalla, Ekambar R. ;   et al. | 2005-04-28 |
Modified protein kinase a-specific oligonucleotides and methods of their use App 20050054600 - Agrawal, Sudhir | 2005-03-10 |
Stabilized immunomodulatory oligonucleotides App 20050026861 - Kandimalla, Ekambar R. ;   et al. | 2005-02-03 |
Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes App 20050026858 - Kandimalla, Ekambar R. ;   et al. | 2005-02-03 |
Synergistic treatment of cancer using immunomers in conjunction with therapeutic agents App 20050009773 - Kandimalla, Ekambar R. ;   et al. | 2005-01-13 |
Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes App 20040266709 - Kandimalla, Ekambar R. ;   et al. | 2004-12-30 |
Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes App 20040266710 - Kandimalla, Ekambar R. ;   et al. | 2004-12-30 |
Modulation of oligonucleotide CpG-mediated immune stimulation by positional modification of nucleosides Grant 6,815,429 - Agrawal November 9, 2 | 2004-11-09 |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by utilizing modified immunostimulatory dinucleotides App 20040198685 - Agrawal, Sudhir ;   et al. | 2004-10-07 |
Short immunomodulatory oligonucleotides App 20040156825 - Agrawal, Sudhir ;   et al. | 2004-08-12 |
Modified protein kinase A-specifc oligonucleotides and methods of their use App 20040106570 - Agrawal, Sudhir | 2004-06-03 |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5' ends App 20040097719 - Agrawal, Sudhir ;   et al. | 2004-05-20 |
Method of down-regulating gene expression App 20040033980 - Agrawal, Sudhir ;   et al. | 2004-02-19 |
Hybrid oligonucleotide phosphorothioates Grant 6,683,167 - Metelev , et al. January 27, 2 | 2004-01-27 |
Modulation of oligonucleotide CpG-mediated immune stimulation by positional modification of nucleosides App 20030236211 - Agrawal, Sudhir ;   et al. | 2003-12-25 |
Use of cyclodextrins to modulate gene expression with reduced immunostimulatory response Grant 6,667,293 - Zhao , et al. December 23, 2 | 2003-12-23 |
Sensitization of cells to cytotoxic agents using oligonucleotides directed to nucleotide excision repair or transcritpion coupled repair genes App 20030232767 - Agrawal, Sudhir ;   et al. | 2003-12-18 |
Mixed backbone oligonucleotides containing pops blocks to obtain reduced phosphorothioate content App 20030220486 - Zhou, Wen-Qiang ;   et al. | 2003-11-27 |
Modulation of oligonucleotides CpG-mediated immune stimulation by positional modification of nucleosides App 20030212029 - Agrawal, Sudhir ;   et al. | 2003-11-13 |
Method of down-regulating gene expression Grant 6,645,943 - Agrawal , et al. November 11, 2 | 2003-11-11 |
Inhibition of infectious agents by exogenous oligonucleotides App 20030191078 - Goodchild, John ;   et al. | 2003-10-09 |
Modulation of oligonucleotide CpG-mediated immune stimulation by positional modification of nucleosides App 20030186912 - Agrawal, Sudhir | 2003-10-02 |
Inhibition of infectious agents by exogenous oligonucleotides App 20030186911 - Goodchild, John ;   et al. | 2003-10-02 |
Modified protein kinase A-specific oligonucleotides and methods of their use Grant 6,624,293 - Agrawal September 23, 2 | 2003-09-23 |
Method of down-regulating gene expression Grant 6,608,035 - Agrawal , et al. August 19, 2 | 2003-08-19 |
Building blocks with carbamate internucleoside linkages and oligonucleotides derived therefrom Grant 6,605,708 - Habus , et al. August 12, 2 | 2003-08-12 |
Use of cyclodextrins to modulate gene expression with reduced immunostimulatory response App 20030148981 - Zhao, Qiuyan ;   et al. | 2003-08-07 |
Hybrid oligonucleotide phosphorothioates App 20030148980 - Metelev, Valeri ;   et al. | 2003-08-07 |
Immunostimulatory activity of CpG oligonucleotides containing non-ionic methylphosophonate linkages App 20030129605 - Yu, Dong ;   et al. | 2003-07-10 |
Antisense oligonucleotides and methods to induce tumor cell death App 20030125287 - Kandimalla, Ekambar R. ;   et al. | 2003-07-03 |
MDM2-specific antisense oligonucleotides App 20030119765 - Chen, Jiandong ;   et al. | 2003-06-26 |
Hyperstructure-forming carriers App 20030109479 - Agrawal, Sudhir | 2003-06-12 |
Modified Protein Kinase A-specific Oligonucleotides And Methods Of Their Use App 20030105035 - AGRAWAL, SUDHIR | 2003-06-05 |
Novel HIV-specific synthetic oligonucleotides and methods of their use App 20030100521 - Agrawal, Sudhir | 2003-05-29 |
Cooperative oligonucleotides App 20030099959 - Kandimalla, Ekambar R. ;   et al. | 2003-05-29 |
Epidermal growth factor receptor antisense oligonucleotides App 20030045494 - Agrawal, Sudhir ;   et al. | 2003-03-06 |
Method For Using Oligonucleotides Having Modified Cpg Dinucleotides App 20030036516 - AGRAWAL, SUDHIR | 2003-02-20 |
Branched oligonucleotides as pathogen-inhibitory agents Grant 6,489,464 - Agrawal , et al. December 3, 2 | 2002-12-03 |
Novel HIV-specific synthetic oligonucleotides and methods of their use App 20020168340 - Agrawal, Sudhir | 2002-11-14 |
Modulation of oligonucleotide CpG-mediated immune stimulation by positional modification of nucleosides Grant 6,476,000 - Agrawal November 5, 2 | 2002-11-05 |
Oligonucleotide mediated specific sytokine induction and reduction of tumor growth in a mammal App 20020151518 - Agrawal, Sudhir ;   et al. | 2002-10-17 |
Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes App 20020137714 - Kandimalla, Ekambar R. ;   et al. | 2002-09-26 |
Modulation of oligonucleotide CpG-mediated immune stimulation by positional modification of nucleosides App 20020132995 - Agrawal, Sudhir ;   et al. | 2002-09-19 |
Oligonucleotide mediated specific cytokine induction and reduction of tumor growth in a mammal Grant 6,426,334 - Agrawal , et al. July 30, 2 | 2002-07-30 |
Hybrid oligonucleotide phosphorothioates App 20020099192 - Metelev, Valeri ;   et al. | 2002-07-25 |
Modulation of oligonucleotide CpG-mediated immune stimulation by positional modification of nucleosides App 20020055475 - Agrawal, Sudhir | 2002-05-09 |
Pseudo-cyclic oligonucleobases Grant 6,383,752 - Agrawal , et al. May 7, 2 | 2002-05-07 |
Cooperative oligonucleotides Grant 6,372,427 - Kandimalla , et al. April 16, 2 | 2002-04-16 |
Hybrid oligonucleotide phosphorothioates Grant 6,346,614 - Metelev , et al. February 12, 2 | 2002-02-12 |
Mixed-backbone Oligonucleotides Containing Pops Blocks To Obtain Reduced Phosphorothioate Content App 20010049436 - ZHOU, WEN-QIANG ;   et al. | 2001-12-06 |
Hyperstructure-forming Carriers App 20010006945 - AGRAWAL, SUDHIR | 2001-07-05 |
Hybrid oligonucleotide phosphorothioates Grant 6,143,881 - Metelev , et al. November 7, 2 | 2000-11-07 |
Primary phosphoramidate internucleoside linkages and oligonucleotides containing the same Grant 6,140,482 - Iyer , et al. October 31, 2 | 2000-10-31 |
MDM2-specific antisense oligonucleotides Grant 6,013,786 - Chen , et al. January 11, 2 | 2000-01-11 |
Inverted chimeric oligonucleotides Grant 5,973,136 - Agrawal October 26, 1 | 1999-10-26 |
Method of modulating gene expression with reduced immunostimulatory response Grant 5,968,909 - Agrawal , et al. October 19, 1 | 1999-10-19 |
Synthesis of oligonucleotides containing alkylphosphonate internucleoside linkages Grant 5,962,674 - Iyer , et al. October 5, 1 | 1999-10-05 |
Process for making oligonucleotides containing o- and s- methylphosphotriester internucleoside linkages Grant 5,955,599 - Iyer , et al. September 21, 1 | 1999-09-21 |
Antisense oligonucleotide alkylphosphonothioates and arylphospohonothioates Grant 5,929,226 - Padmapriya , et al. July 27, 1 | 1999-07-27 |
Affinity-based purification of oligonucleotides using soluble multimeric oligonucleotides Grant 5,912,332 - Agrawal , et al. June 15, 1 | 1999-06-15 |
Mixed backbone antisense oligonucleotides containing 2'-5'-ribonucleotide- and 3'-5'-deoxyribonucleotides segments Grant 5,886,165 - Kandimalla , et al. March 23, 1 | 1999-03-23 |
Oligonucleotides having modified CpG dinucleosides Grant 5,856,462 - Agrawal January 5, 1 | 1999-01-05 |
Detritylation of DMT-oligonucleotides using cationic ion-exchange resin Grant 5,808,042 - Iyer , et al. September 15, 1 | 1998-09-15 |
CAPL-specific oligonucleotides and method of inhibiting metastatic cancer Grant 5,789,248 - Fodstad , et al. August 4, 1 | 1998-08-04 |
Inverted chimeric and hybrid oligonucleotides Grant 5,773,601 - Agrawal June 30, 1 | 1998-06-30 |
Methods and compounds for the stereoselective enrichment of oligonucleotide diastereomers and oligonucleotides thereby produced Grant 5,750,674 - Iyer , et al. May 12, 1 | 1998-05-12 |
Integrated oligonucleotides Grant 5,739,308 - Kandimalla , et al. April 14, 1 | 1998-04-14 |
Triplex-forming antisense oligonucleotides having abasic linkers targeting nucleic acids comprising mixed sequences of purines and pyrimidines Grant 5,693,773 - Kandimalla , et al. December 2, 1 | 1997-12-02 |
Cyclodextrin cellular delivery system for oligonucleotides Grant 5,691,316 - Agrawal , et al. November 25, 1 | 1997-11-25 |
Therapeutic anti-HIV anti-viral oligonucleotides and pharmaceutical formulations thereof Grant 5,684,147 - Agrawal , et al. November 4, 1 | 1997-11-04 |
Hybrid oligonucleotide phosphorothioates Grant 5,652,355 - Metelev , et al. July 29, 1 | 1997-07-29 |
Inverted chimeric and hybrid oligonucleotides Grant 5,652,356 - Agrawal July 29, 1 | 1997-07-29 |
Influenza virus replication inhibiting oligonucleotide analogues and their pharmaceutical compositions Grant 5,637,573 - Agrawal , et al. June 10, 1 | 1997-06-10 |
Method of site-specific alteration of RNA and production of encoded polypeptides Grant 5,635,377 - Pederson , et al. June 3, 1 | 1997-06-03 |
Method of synthesizing radioisotopically labeled oligonucleotides by direct solid-phase 5' phosphitylation Grant 5,631,361 - Tan , et al. May 20, 1 | 1997-05-20 |
5-pentenoyl moiety as a nucleoside-amino protecting group, 4-pentenoyl-protected nucleotide synthons, and related oligonucleotide syntheses Grant 5,614,622 - Iyer , et al. March 25, 1 | 1997-03-25 |
Cyclodextrin cellular delivery system for oligonucleotides Grant 5,605,890 - Agrawal , et al. February 25, 1 | 1997-02-25 |
Method of down-regulating gene expression Grant 5,591,721 - Agrawal , et al. January 7, 1 | 1997-01-07 |
Linear aminoalkylphosphoramidate oligonucleotide derivatives Grant 5,563,253 - Agrawal , et al. October 8, 1 | 1996-10-08 |
Aminoalkylphosphotriester oligonucleotide derivatives Grant 5,541,306 - Agrawal , et al. July 30, 1 | 1996-07-30 |
Aminoalkylphosphorothioamidate oligonucleotide deratives Grant 5,536,821 - Agrawal , et al. July 16, 1 | 1996-07-16 |
Oligonucleotide multiple reporter precursors Grant 5,510,475 - Agrawal , et al. April 23, 1 | 1996-04-23 |
Method for sequencing synthetic oligonucleotides containing non-phosphodiester internucleotide linkages Grant 5,403,709 - Agrawal , et al. April 4, 1 | 1995-04-04 |
Method of site-specific alteration of RNA and production of encoded polypeptides Grant 5,366,878 - Pederson , et al. November 22, 1 | 1994-11-22 |
Site-specific functionalization of oligodeoxynucleotides for non-radioactive labelling Grant 5,321,131 - Agrawal , et al. June 14, 1 | 1994-06-14 |
Method of site-specific alteration of RNA and production of encoded polypeptides Grant 5,220,007 - Pederson , et al. June 15, 1 | 1993-06-15 |
Inhibition of influenza virus replication by oligonucleotide phosphorothioates Grant 5,194,428 - Agrawal , et al. March 16, 1 | 1993-03-16 |
Process for synthesizing oligonucleotides and their analogs adaptable to large scale syntheses Grant 5,149,798 - Agrawal , et al. September 22, 1 | 1992-09-22 |
Method of site-specific alteration of RNA and production of encoded polypeptides Grant 5,149,797 - Pederson , et al. September 22, 1 | 1992-09-22 |