| Patent | Date |
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Crystal Forms of (S)-4-(8-amino-3-(1-(but-2-ynoyl)-pyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1- -yl)-n-(pyridin-2-yl)benzamide
App 20220177476 - Blatter; Frtiz ; et al. | 2022-06-09 |
PROCESSES FOR THE PREPARATION OF 4-{8-AMINO-3-[(2S)-1-(BUT-2-YNOYL)-PYRROLIDIN-2-YL]IMIDAZO[1,5-a]-PYRAZIN- -1-YL}N-(PYRIDIN-2-YL)-BENZAMIDE
App 20220127270 - BETHEL; Paul Allen ; et al. | 2022-04-28 |
Therapeutic Combinations of a BTK Inhibitor, a PI3K Inhibitor, a JAK-2 Inhibitor, and/or a BCL-2 Inhibitor
App 20220088013 - Hamdy; Ahmed ; et al. | 2022-03-24 |
BTK Inhibitors to Treat Solid Tumors Through Modulation of the Tumor Microenvironment
App 20210346382 - Hamdy; Ahmed ; et al. | 2021-11-11 |
Therapeutic combinations of a BTK inhibitor, a PI3K inhibitor, a JAK-2 inhibitor, and/or a BCL-2 inhibitor
Grant 11,166,951 - Hamdy , et al. November 9, 2 | 2021-11-09 |
Therapeutic combinations of a MEK inhibitor and a BTK inhibitor
Grant 11,154,554 - Rothbaum , et al. October 26, 2 | 2021-10-26 |
Methods of Treating Cancers, Immune and Autoimmune Diseases, and Inflammatory Diseases Based on BTK Occupancy and BTK Resynthesis Rate
App 20210322408 - Lannutti; Brian ; et al. | 2021-10-21 |
Imidazopyrazine inhibitors of Bruton's tyrosine kinase
Grant 11,110,088 - Barf , et al. September 7, 2 | 2021-09-07 |
Methods of treating chronic lymphocytic leukemia and small lymphocytic leukemia using a BTK inhibitor
Grant 11,090,302 - Hamdy , et al. August 17, 2 | 2021-08-17 |
Crystal forms of (S)-4-(8-amino-3-(1-(but-2-ynoyl)pyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1-- yl)-N-(pyridin-2-yl)benzamide maleate
Grant 11,059,829 - Blatter , et al. July 13, 2 | 2021-07-13 |
Imidazopyrazine inhibitors of Bruton's tyrosine kinase
Grant 10,858,364 - Podoll , et al. December 8, 2 | 2020-12-08 |
Imidazopyrazine Inhibitors of Bruton's Tyrosine Kinase
App 20200330461 - Barf; Tjeerd ; et al. | 2020-10-22 |
Crystal Forms of (S)-4-(8-amino-3-(1-(but-2-ynoyl)-pyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1- -yl)-N-(pyridin-2-yl)benzamide malea
App 20200255437 - Kind Code | 2020-08-13 |
Imidazopyrazine inhibitors of Bruton's tyrosine kinase
Grant 10,736,893 - Barf , et al. A | 2020-08-11 |
Pharmaceutical composition comprising a crystal form of (S)-4-(8-amino-3-(1-(but-2-ynoyl)pyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1-- yl)-N-(pyridin-2-yl)benzamide for treating diffuse large B-cell lymphoma
Grant 10,640,509 - Blatter , et al. | 2020-05-05 |
Therapeutic Combinations of an IRAK4 Inhibitor and a BTK Inhibitor
App 20200069668 - Lannutti; Brian ; et al. | 2020-03-05 |
Therapeutic Combinations of a BTK Inhibitor, a PI3K Inhibitor, a JAK-2 Inhibitor, a PD-1 Inhibitor, and/or a PD-L1 Inhibitor
App 20200069796 - Hamdy; Ahmed ; et al. | 2020-03-05 |
BTK Inhibitors to Treat Solid Tumors Through Modulation of the Tumor Microenvironment
App 20190381044 - Hamdy; Ahmed ; et al. | 2019-12-19 |
Therapeutic Combinations of a MEK Inhibitor and a BTK Inhibitor
App 20190374539 - Rothbaum; Wayne ; et al. | 2019-12-12 |
Compositions and Methods for the Assessment of Drug Target Occupancy for Bruton's Tyrosine Kinase
App 20190376971 - Barf; Tjeerd ; et al. | 2019-12-12 |
Therapeutic Combinations of an Antifolate and a BTK Inhibitor
App 20190374543 - Kaptein; Allard ; et al. | 2019-12-12 |
Therapeutic Combination of a PI3K Inhibitor and a BTK Inhibitor
App 20190358235 - HAMDY; Ahmed ; et al. | 2019-11-28 |
Imidazopyrazine Inhibitors of Bruton's Tyrosine Kinase
App 20190345164 - Podoll; Terry ; et al. | 2019-11-14 |
Solid Forms and Formulations of Imidazopyrazine Compound
App 20190337949 - Blatter; Fritz ; et al. | 2019-11-07 |
Methods And Compositions For Use Of Therapeutic T Cells In Combination With Kinase Inhibitors
App 20190328786 - PORTS; Michael ; et al. | 2019-10-31 |
Methods of Treating Cancers, Immune and Autoimmune Diseases, and Inflammatory Diseases Based on BTK Occupancy and BTK Resynthesi
App 20190314369 - Lannutti; Brian ; et al. | 2019-10-17 |
Methods of Treating Chronic Lymphocytic Leukemia and Small Lymphocytic Leukemia Using a BTK Inhibitor
App 20190290644 - Hamdy; Ahmed ; et al. | 2019-09-26 |
Methods of Blocking the CXCR-4/SDF-1 Signaling Pathway With Inhibitors of Bruton's Tyrosine Kinase
App 20190231775 - Izumi; Raquel ; et al. | 2019-08-01 |
Therapeutic Combinations of a Proteasome Inhibitor and a BTK Inhibitor
App 20190209591 - Lannutti; Brian ; et al. | 2019-07-11 |
Therapeutic combination of PI3K inhibitor and a BTK inhibitor
Grant 10,328,080 - Hamdy , et al. | 2019-06-25 |
Methods of treating chronic lymphocytic leukemia and small lymphocytic leukemia using a BTK inhibitor
Grant 10,272,083 - Hamdy , et al. | 2019-04-30 |
Therapeutic Combinations of a BTK Inhibitor and a GITR Binding Molecule, a 4-1BB Agonist, or an OX40 Agonist
App 20190022092 - Rothbaum; Wayne ; et al. | 2019-01-24 |
Therapeutic Combinations of an Antifolate and a BTK Inhibitor
App 20190008869 - Kaptein; Allard ; et al. | 2019-01-10 |
Therapeutic Combinations of a MEK Inhibitor and a BTK Inhibitor
App 20190008859 - Rothbaum; Wayne ; et al. | 2019-01-10 |
Pharmaceutical composition comprising a crystal form of (S)-4-(8-amino-3-(1-(but-2-ynoyl) pyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1-yl)-N-(pyridin-2-yl)benzamide
Grant 10,167,291 - Blatter , et al. J | 2019-01-01 |
BTK Inhibitors to Treat Solid Tumors Through Modulation of the Tumor Microenvironment
App 20180369244 - Hamdy; Ahmed ; et al. | 2018-12-27 |
Imidazopyrazine Inhibitors of Bruton's Tyrosine Kinase
App 20180318297 - Barf; Tjeerd ; et al. | 2018-11-08 |
Methods of Using BTK Inhibitors to Treat Dermatoses
App 20180318304 - Krejsa; Cecile M. | 2018-11-08 |
Therapeutic Combinations of a BTK Inhibitor, a PI3K Inhibitor, a JAK-2 Inhibitor, and/or a CDK4/6 Inhibitor
App 20180250400 - Hamdy; Ahmed ; et al. | 2018-09-06 |
Therapeutic Combinations of a BTK Inhibitor, a PI3K Inhibitor, a JAK-2 Inhibitor, and/or a BCL-2 Inhibitor
App 20180250298 - Hamdy; Ahmed ; et al. | 2018-09-06 |
Solid Forms and Formulations of Imidazopyrazine Compound
App 20180208596 - Blatter; Fritz ; et al. | 2018-07-26 |
Therapeutic Combinations of a BTK Inhibitor, a PI3K Inhibitor and/or a JAK-2 Inhibitor
App 20180207154 - Hamdy; Ahmed ; et al. | 2018-07-26 |
Methods of Blocking the CXCR-4/SDF-1 Signaling Pathway With Inhibitors of Bruton's Tyrosine Kinase
App 20180193337 - Izumi; Raquel ; et al. | 2018-07-12 |
Therapeutic combinations of a BTK inhibitor, a PI3K inhibitor and/or a JAK-2 inhibitor
Grant 9,949,971 - Hamdy , et al. April 24, 2 | 2018-04-24 |
Methods of blocking the CXCR-4/SDF-1 signaling pathway with inhibitors of bruton's tyrosine kinase
Grant 9,937,171 - Izumi , et al. April 10, 2 | 2018-04-10 |
Crystal forms of (S)-4-(8-amino-3-(1-(but-2-ynoyl)pyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1-- yl)-N-(pyridin-2-yl)benzamide
Grant 9,796,721 - Blatter , et al. October 24, 2 | 2017-10-24 |
Therapeutic Combination of PI3K Inhibitor and a BTK Inhibitor
App 20170266191 - Hamdy; Ahmed ; et al. | 2017-09-21 |
Therapeutic Combinations of a BTK Inhibitor, a PI3K Inhibitor, a JAK-2 Inhibitor, a PD-1 Inhibitor, and/or a PD-L1 Inhibitor
App 20170239351 - Hamdy; Ahmed ; et al. | 2017-08-24 |
BTK Inhibitors to Treat Solid Tumors Through Modulation of the Tumor Microenvironment
App 20170231995 - Hamdy; Ahmed ; et al. | 2017-08-17 |
Therapeutic Combinations of a BTK Inhibitor, a PI3K Inhibitor, a JAK-2 Inhibitor, and/or a BCL-2 Inhibitor
App 20170231986 - Hamdy; Ahmed ; et al. | 2017-08-17 |
Therapeutic Combinations of a BTK Inhibitor, a PI3K Inhibitor, a JAK-2 Inhibitor, and/or a CDK 4/6 Inhibitor
App 20170224819 - Hamdy; Ahmed ; et al. | 2017-08-10 |
Methods of Using BTK Inhibitors to Treat Dermatoses
App 20170224688 - Krejsa; Cecile M. | 2017-08-10 |
Methods of Treating Cancers, Immune and Autoimmune Diseases, and Inflammatory Diseases Based on BTK Occupancy and BTK Resynthesis Rate
App 20170143712 - Lannutti; Brian ; et al. | 2017-05-25 |
Therapeutic Combinations of a BTK Inhibitor, a PI3K Inhibitor and/or a JAK-2 Inhibitor
App 20170136014 - Hamdy; Ahmed ; et al. | 2017-05-18 |
Methods of Treating Chronic Lymphocytic Leukemia and Small Lymphocytic Leukemia Using a BTK Inhibitor
App 20170095471 - Ahmed; Hamdy ; et al. | 2017-04-06 |
Therapeutic Combinations of a Proteasome Inhibitor and a BTK Inhibitor
App 20170071962 - Lannutti; Brian ; et al. | 2017-03-16 |
Therapeutic Combinations of an IRAK4 Inhibitor and a BTK Inhibitor
App 20170035881 - Lannutti; Brian ; et al. | 2017-02-09 |
Methods Of Blocking The Cxcr-4/sdf-1 Signaling Pathway With Inhibitors Of Bruton's Tyrosine Kinase
App 20170035756 - IZUMI; Raquel ; et al. | 2017-02-09 |
Solid Forms and Formulations of Imidazopyrazine Compound
App 20170029428 - Blatter; Fritz ; et al. | 2017-02-02 |
Bruton's tyrosine kinase inhibitors for hematopoietic mobilization
Grant 9,522,917 - Izumi , et al. December 20, 2 | 2016-12-20 |
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