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Conjugated complement cascade inhibitors
Grant 7,482,376 - Subasinghe , et al. January 27, 2 | 2009-01-27 |
C-fms kinase inhibitors
Grant 7,429,603 - Player , et al. September 30, 2 | 2008-09-30 |
Thiophene amidines, compositions thereof, and methods of treating complement-mediated diseases and conditions
Grant 7,138,530 - Subasinghe , et al. November 21, 2 | 2006-11-21 |
Methods of using analogs of human basic fibroblast growth factor mutated at one or more of the positions glutamate 89, asparate 101 or leucine 137
Grant 7,138,374 - Springer , et al. November 21, 2 | 2006-11-21 |
Thiophene amidines, compositions thereof, and methods of treating complement-mediated diseases and conditions
Grant 7,109,354 - Subasinghe , et al. September 19, 2 | 2006-09-19 |
Quinazolinones
Grant 7,060,706 - Mederski , et al. June 13, 2 | 2006-06-13 |
Substituted indoles and their use as integrin antagonists
App 20050250771 - Lu, Tianbo ; et al. | 2005-11-10 |
Azacycloalkanone serine protease inhibitors
Grant 6,962,942 - Miller , et al. November 8, 2 | 2005-11-08 |
Substituted benzofurans and benzothiophenes, methods of making and methods of use as integrin antagonists
App 20050228011 - Anaclerio, Beth M. ; et al. | 2005-10-13 |
Substituted indoles and their use as integrin antagonists
App 20050209225 - Lu, Tianbao ; et al. | 2005-09-22 |
Substituted benzofurans and benzothiophenes, methods of making and methods of use as integrin antagonists
App 20050165036 - Anaclerio, Beth M. ; et al. | 2005-07-28 |
Analogs of human basic fibroblast growth factor mutated at one or more of the positions glutamate 89, asparate 101 or leucine 137
App 20050159350 - Springer, Barry A. ; et al. | 2005-07-21 |
Aminopyridyl-substituted phenyl acetamides as protease inhibitors
Grant 6,900,231 - Pan , et al. May 31, 2 | 2005-05-31 |
Quinazolinones
Grant 6,890,930 - Mederski , et al. May 10, 2 | 2005-05-10 |
Substituted benzofurans and benzothiophenes, methods of making and methods of use as integrin antagonists
Grant 6,872,730 - Anaclerio , et al. March 29, 2 | 2005-03-29 |
Analogs of human basic fibroblast growth factor mutated at one or more of the positions glutamate 89, Aspartate 101 or Leucine 137
Grant 6,767,722 - Springer , et al. July 27, 2 | 2004-07-27 |
Heteroaryl aminoguanidines and alkoxyguanidines and their use as protease inhibitors
App 20040106633 - Lu, Tianbao ; et al. | 2004-06-03 |
Methods of using analogs of human basic fibroblast growth factor mutated at one or more of the positions glutamate 89, aspartate 101 or leucine 137
Grant 6,737,404 - Springer , et al. May 18, 2 | 2004-05-18 |
Process for preparing aminoguanidines and alkoxyguanidines as protease inhibitors
Grant 6,730,783 - Tomczuk , et al. May 4, 2 | 2004-05-04 |
Aminoguanidines and alkoxyguanidines as protease inhibitors
Grant 6,706,765 - Tomczuk , et al. March 16, 2 | 2004-03-16 |
Heteroaryl aminoguanidines and alkoxyguanidines and their use as protease inhibitors
Grant 6,706,021 - Lu , et al. March 16, 2 | 2004-03-16 |
Novel thiophene amidines, compositions thereof, and methods of treating complement-mediated diseases and conditions
App 20040009995 - Subasinghe, Nalin ; et al. | 2004-01-15 |
Process for preparing aminoguanidines and alkoxyguanidines as protease inhibitors
App 20040002539 - Tomczuk, Bruce E. ; et al. | 2004-01-01 |
Heteroaryl aminoguanidines and alkoxyguanidines and their use as protease inhibitors
App 20030225115 - Lu, Tianbao ; et al. | 2003-12-04 |
Substituted thiazoles and the use thereof as inhibitors of plasminogen activator inhibitor-1
App 20030220380 - Dhanoa, Dale S. ; et al. | 2003-11-27 |
Aminoguanidines and alkoxyguanidines as protease inhibitors
Grant 6,638,931 - Tomczuk , et al. October 28, 2 | 2003-10-28 |
Microplate thermal shift assay for ligand development using 5- (4"-dimethylaminophenyl) -2- (4' -phenyl) oxazole derivative fluorescent dyes
App 20030175813 - Pantoliano, Michael W. ; et al. | 2003-09-18 |
Aminoguanidines and alkoxyguanidines as protease inhibitors
App 20030158252 - Tomczuk, Bruce E. ; et al. | 2003-08-21 |
Substituted thiazoles and the use thereof as inhibitors of plasminogen activator inhibitor-1
Grant 6,586,453 - Dhanoa , et al. July 1, 2 | 2003-07-01 |
Azacycloalkanone serine protease inhibitors
App 20030109517 - Miller, Scott C. ; et al. | 2003-06-12 |
Substituted diphenyloxazoles, the synthesis thereof, and the use thereof as fluorescence probes
App 20030105111 - Carver, Theodore E. JR. ; et al. | 2003-06-05 |
Method, system and computer program product for non-linear mapping of multi-dimensional data
Grant 6,571,227 - Agrafiotis , et al. May 27, 2 | 2003-05-27 |
Microplate thermal shift assay for ligand development using 5-(4"dimethylaminophenyl)-2-(4'-phenyl)oxazole derivative fluorescent dyes
Grant 6,569,631 - Pantoliano , et al. May 27, 2 | 2003-05-27 |
Heteroaryl aminoguanidines and alkoxyguanidines and their use as protease inhibitors
App 20030087921 - Lu, Tianbao ; et al. | 2003-05-08 |
Aminopyridyl-substituted phenyl acetamides as protease inhibitors
App 20030073833 - Pan, Wenxi ; et al. | 2003-04-17 |
Cyclic oxyguanidine pyrazinones as protease inhibitors
App 20030073702 - Wang, Aihua ; et al. | 2003-04-17 |
Conductive microtiter plate
App 20030064508 - Kwasnoski, Joseph ; et al. | 2003-04-03 |
Compounds and compositions for treating C1s-mediated diseases and conditions
Grant 6,515,002 - Illig , et al. February 4, 2 | 2003-02-04 |
Substituted benzofurans and benzothiophenes, methods of making and methods of use as integrin antagonists
App 20030018064 - Anaclerio, Beth M. ; et al. | 2003-01-23 |
System, method and computer program product for identifying chemical compounds having desired properties
App 20030014191 - Agrafiotis, Dimitris K. ; et al. | 2003-01-16 |
Use of 1,3-substituted pyrazol-5-yl sulfonates as pesticides
Grant 6,506,784 - Dhanoa , et al. January 14, 2 | 2003-01-14 |
Microtiter plate with integral heater
App 20020179590 - Kwasnoski, Joseph ; et al. | 2002-12-05 |
System, method, and computer program product for representing proximity data in a multi-dimensional space
Grant 6,453,246 - Agrafiotis , et al. September 17, 2 | 2002-09-17 |
Method of generating chemical compounds having desired properties
Grant 6,434,490 - Agrafiotis , et al. August 13, 2 | 2002-08-13 |
Method, system, and computer program product for representing object relationships in a multidimensional space
App 20020099675 - Agrafiotis, Dimitris K. ; et al. | 2002-07-25 |
Microtiter plate with integral heater
Grant 6,423,948 - Kwasnoski , et al. July 23, 2 | 2002-07-23 |
Heteroaryl protease inhibitors and diagnostic imaging agents
Grant 6,420,397 - Pan , et al. July 16, 2 | 2002-07-16 |
System, method and computer program product for identifying chemical compounds having desired properties
Grant 6,421,612 - Agrafiotis , et al. July 16, 2 | 2002-07-16 |
Amidino protease inhibitors
Grant 6,414,020 - Lu , et al. July 2, 2 | 2002-07-02 |
Microtiter Plate With Integral Heater
App 20020070208 - Kwasnoski, Joseph ; et al. | 2002-06-13 |
Heteroaryl amidines, methylamidines and guanidines, and use thereof as protease inhibitors
Grant 6,403,633 - Illig , et al. June 11, 2 | 2002-06-11 |
Cyclic oxyguanidine pyrazinones as protease inhibitors
App 20020052357 - Wang, Aihua ; et al. | 2002-05-02 |
Tetrahydroisoquinoline-3-carboxylic acid alkoxyguanidines as integrin antagonists
App 20020037897 - Wang, Aihua | 2002-03-28 |
Compounds and compositons for treating C1s-mediated diseases and conditions
App 20020037915 - Illig, Carl R. ; et al. | 2002-03-28 |
Cyclic oxyguanidine protease inhibitors
App 20020022615 - Wang, Aihua ; et al. | 2002-02-21 |
Substituted thiazoles and the use thereof as inhibitors of plasminogen activator inhibitor-1
App 20010044545 - Dhanoa, Dale S. ; et al. | 2001-11-22 |
Aminoguanidines and alkoxyguanidines as protease inhibitors
App 20010037039 - Tomczuk, Bruce E. ; et al. | 2001-11-01 |
Method for identifying lead compounds
Grant 6,303,322 - Pantoliano , et al. October 16, 2 | 2001-10-16 |
Method and computer program product for designing combinatorial arrays
App 20010029026 - Agrafiotis, Dimitris K. ; et al. | 2001-10-11 |
Amidino protease inhibitors
App 20010025041 - Lu, Tianbao ; et al. | 2001-09-27 |
Method, system, and computer program product for representing similarity/dissimilarity between chemical compounds
Grant 6,295,514 - Agrafiotis , et al. September 25, 2 | 2001-09-25 |
Method for identifying conditions that facilitate recombinant protein folding
Grant 6,291,192 - Pantoliano , et al. September 18, 2 | 2001-09-18 |
Analogs of human basic fibroblast growth factor
App 20010020004 - Springer, Barry A. ; et al. | 2001-09-06 |
Analogs of human basic fibroblast growth factor mutated at one or more of the positions glutamute 89, aspartate 101 or leucine 137
Grant 6,274,712 - Springer , et al. August 14, 2 | 2001-08-14 |
Method for determining conditions that facilitate protein crystallization
Grant 6,268,158 - Pantoliano , et al. July 31, 2 | 2001-07-31 |
Method for sensing and processing fluorescence data from multiple samples
Grant 6,268,218 - Pantoliano , et al. July 31, 2 | 2001-07-31 |
Heteroaryl aminoguanidines and alkoxyguanidines and their use as protease inhibitors
Grant 6,245,763 - Lu , et al. June 12, 2 | 2001-06-12 |
Microplate thermal shift assay apparatus for ligand development and multi-variable protein chemistry optimization
Grant 6,214,293 - Pantoliano , et al. April 10, 2 | 2001-04-10 |
Aminobenzenedicarboxylic acid-based combinatorial libraries
Grant 6,127,191 - Graybill , et al. October 3, 2 | 2000-10-03 |
Microplate thermal shift assay apparatus for ligand development and multi-variable protein chemistry optimization
Grant 6,036,920 - Pantoliano , et al. March 14, 2 | 2000-03-14 |
Heteroaryl aminoguanidines and alkoxyguanidines and their use as protease inhibitors
Grant 6,037,356 - Lu , et al. March 14, 2 | 2000-03-14 |
Microplate thermal shift assay for ligand development and multi-variable protein chemistry optimization
Grant 6,020,141 - Pantoliano , et al. February 1, 2 | 2000-02-01 |
System, method, and computer program product for at least partially automatically generating chemical compounds with desired properties from a list of potential chemical compounds to synthesize
Grant 5,901,069 - Agrafiotis , et al. May 4, 1 | 1999-05-04 |
Amidinohydrazones as protease inhibitors
Grant 5,891,909 - Soll , et al. April 6, 1 | 1999-04-06 |
Guanidino protease inhibitors
Grant 5,792,769 - Lu , et al. August 11, 1 | 1998-08-11 |
Arylsulfonylaminobenzene derivatives and the use thereof as factor Xa inhibitors
Grant 5,741,819 - Illig , et al. April 21, 1 | 1998-04-21 |
System, method, and computer program for at least partially automatically generating chemical compounds having desired properties
Grant 5,684,711 - Agrafiotis , et al. November 4, 1 | 1997-11-04 |
Thrombin inhibitors
Grant 5,612,369 - Bone , et al. March 18, 1 | 1997-03-18 |
System and method of automatically generating chemical compounds with desired properties
Grant 5,574,656 - Agrafiotis , et al. November 12, 1 | 1996-11-12 |
N,N-disulfonylated aminobenzene carboxlic acids and the use thereof as thrombin inhibitors
Grant 5,559,150 - Soll September 24, 1 | 1996-09-24 |
System and method of automatically generating chemical compounds with desired properties
Grant 5,463,564 - Agrafiotis , et al. October 31, 1 | 1995-10-31 |
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